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Items: 1 to 50 of 251

1.

National trends in prescription drug expenditures and projections for 2019.

Schumock GT, Stubbings J, Hoffman JM, Wiest MD, Suda KJ, Rim MH, Tadrous M, Tichy EM, Cuellar S, Clark JS, Matusiak LM, Hunkler RJ, Vermeulen LC.

Am J Health Syst Pharm. 2019 Jun 14. pii: zxz109. doi: 10.1093/ajhp/zxz109. [Epub ahead of print]

PMID:
31199861
2.

CD31-positive microvessel density within adenomas of Lynch Syndrome patients is similar compared to adenomas of non-Lynch patients.

Vleugels JLA, van Neerven SM, van Leerdam ME, Wanders LK, de Wit M, Carvalho B, Delis-van Diemen PM, Kallenberg FGJ, Vermeulen L, Beliën JA, East JE, Meijer GA, Dekker E.

Endosc Int Open. 2019 May;7(5):E701-E707. doi: 10.1055/a-0832-8283. Epub 2019 May 8.

3.

Stem cells in homeostasis and cancer of the gut.

van der Heijden M, Vermeulen L.

Mol Cancer. 2019 Mar 30;18(1):66. doi: 10.1186/s12943-019-0962-x. Review.

4.

Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts.

van der Heijden M, Miedema DM, Waclaw B, Veenstra VL, Lecca MC, Nijman LE, van Dijk E, van Neerven SM, Lodestijn SC, Lenos KJ, de Groot NE, Prasetyanti PR, Arricibita Varea A, Winton DJ, Medema JP, Morrissey E, Ylstra B, Nowak MA, Bijlsma MF, Vermeulen L.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6140-6145. doi: 10.1073/pnas.1813417116. Epub 2019 Mar 8.

5.

Prognostic value of low CDX2 expression in colorectal cancers with a high stromal content - a short report.

Sandberg TP, Sweere I, van Pelt GW, Putter H, Vermeulen L, Kuppen PJ, Tollenaar RAEM, Mesker WE.

Cell Oncol (Dordr). 2019 Jun;42(3):397-403. doi: 10.1007/s13402-019-00436-0. Epub 2019 Mar 8.

PMID:
30847807
6.

The interplay between intrinsic and extrinsic Wnt signaling in controlling intestinal transformation.

van Neerven SM, Vermeulen L.

Differentiation. 2019 Feb 14. pii: S0301-4681(18)30168-3. doi: 10.1016/j.diff.2019.02.002. [Epub ahead of print] Review.

7.

Cancer stem cells: here, there, and everywhere.

Lodestijn SC, Lenos KJ, Miedema DM, Bijlsma MF, Vermeulen L.

Mol Cell Oncol. 2018 Dec 4;6(1):1540235. doi: 10.1080/23723556.2018.1540235. eCollection 2019.

PMID:
30788417
8.

Integrative network biology analysis identifies miR-508-3p as the determinant for the mesenchymal identity and a strong prognostic biomarker of ovarian cancer.

Zhao L, Wang W, Xu L, Yi T, Zhao X, Wei Y, Vermeulen L, Goel A, Zhou S, Wang X.

Oncogene. 2019 Mar;38(13):2305-2319. doi: 10.1038/s41388-018-0577-5. Epub 2018 Nov 26.

PMID:
30478449
9.

Cryptosporidium concentrations in rivers worldwide.

Vermeulen LC, van Hengel M, Kroeze C, Medema G, Spanier JE, van Vliet MTH, Hofstra N.

Water Res. 2019 Feb 1;149:202-214. doi: 10.1016/j.watres.2018.10.069. Epub 2018 Oct 30.

10.

Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data.

Trinh A, Lädrach C, Dawson HE, Ten Hoorn S, Kuppen PJK, Reimers MS, Koopman M, Punt CJA, Lugli A, Vermeulen L, Zlobec I.

Br J Cancer. 2018 Nov;119(10):1244-1251. doi: 10.1038/s41416-018-0230-7. Epub 2018 Nov 2.

PMID:
30385823
11.

ASHP Foundation Pharmacy Forecast 2019: Strategic Planning Advice for Pharmacy Departments in Hospitals and Health Systems.

Vermeulen LC, Eddington ND, Gourdine MA, Jorgenson J, Kvancz DA, Nesbit SA, Bicket MC, Zellmer WA, Hine A, Belford S, Peters SG, Hoffman JM, Schwab WE, Knoer S, Cosgrove DT, Kent SS, Clark JS.

Am J Health Syst Pharm. 2019 Jan 16;76(2):71-100. doi: 10.2146/sp180010. No abstract available.

PMID:
30373935
12.
13.

What Will We Expect From Novel Therapies to Esophageal and Gastric Malignancies?

De Mello RA, Castelo-Branco L, Castelo-Branco P, Pozza DH, Vermeulen L, Palacio S, Salzberg M, Lockhart AC.

Am Soc Clin Oncol Educ Book. 2018 May 23;38:249-261. doi: 10.1200/EDBK_198805. Review.

PMID:
30231398
14.

Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.

Lenos KJ, Miedema DM, Lodestijn SC, Nijman LE, van den Bosch T, Romero Ros X, Lourenço FC, Lecca MC, van der Heijden M, van Neerven SM, van Oort A, Leveille N, Adam RS, de Sousa E Melo F, Otten J, Veerman P, Hypolite G, Koens L, Lyons SK, Stassi G, Winton DJ, Medema JP, Morrissey E, Bijlsma MF, Vermeulen L.

Nat Cell Biol. 2018 Oct;20(10):1193-1202. doi: 10.1038/s41556-018-0179-z. Epub 2018 Sep 3.

15.

Photothermally Triggered Endosomal Escape and Its Influence on Transfection Efficiency of Gold-Functionalized JetPEI/pDNA Nanoparticles.

Vermeulen LMP, Fraire JC, Raes L, De Meester E, De Keulenaer S, Van Nieuwerburgh F, De Smedt S, Remaut K, Braeckmans K.

Int J Mol Sci. 2018 Aug 14;19(8). pii: E2400. doi: 10.3390/ijms19082400.

16.

Community orientation of general practitioners in 34 countries.

Vermeulen L, Schäfer W, Pavlic DR, Groenewegen P.

Health Policy. 2018 Oct;122(10):1070-1077. doi: 10.1016/j.healthpol.2018.06.012. Epub 2018 Jun 30.

PMID:
30041912
17.

Exploration Strategies for Discovery of Interactivity in Visualizations.

Blascheck T, Vermeulen LM, Vermeulen J, Perin C, Willett W, Ertl T, Carpendale S.

IEEE Trans Vis Comput Graph. 2019 Feb;25(2):1407-1420. doi: 10.1109/TVCG.2018.2802520. Epub 2018 Feb 5.

PMID:
29993602
18.

The proton sponge hypothesis: Fable or fact?

Vermeulen LMP, De Smedt SC, Remaut K, Braeckmans K.

Eur J Pharm Biopharm. 2018 Aug;129:184-190. doi: 10.1016/j.ejpb.2018.05.034. Epub 2018 May 30. Review.

PMID:
29859281
19.

Itraconazole targets cell cycle heterogeneity in colorectal cancer.

Buczacki SJA, Popova S, Biggs E, Koukorava C, Buzzelli J, Vermeulen L, Hazelwood L, Francies H, Garnett MJ, Winton DJ.

J Exp Med. 2018 Jul 2;215(7):1891-1912. doi: 10.1084/jem.20171385. Epub 2018 May 31.

20.

Young GI angle: how to write a good conference abstract.

Krajewska J, Vermeulen L.

United European Gastroenterol J. 2018 Apr;6(3):482-484. doi: 10.1177/2050640618765848. Epub 2018 Mar 22. No abstract available.

21.

National trends in prescription drug expenditures and projections for 2018.

Schumock GT, Stubbings J, Wiest MD, Li EC, Suda KJ, Matusiak LM, Hunkler RJ, Vermeulen LC.

Am J Health Syst Pharm. 2018 Jul 15;75(14):1023-1038. doi: 10.2146/ajhp180138. Epub 2018 May 10.

PMID:
29748254
22.

Turning Cold Tumors Hot by Blocking TGF-β.

Ros XR, Vermeulen L.

Trends Cancer. 2018 May;4(5):335-337. doi: 10.1016/j.trecan.2018.03.005. Epub 2018 Mar 30.

PMID:
29709256
23.

Classification of Colorectal Cancer in Molecular Subtypes by Immunohistochemistry.

Ten Hoorn S, Trinh A, de Jong J, Koens L, Vermeulen L.

Methods Mol Biol. 2018;1765:179-191. doi: 10.1007/978-1-4939-7765-9_11.

PMID:
29589308
24.

Endosomal Size and Membrane Leakiness Influence Proton Sponge-Based Rupture of Endosomal Vesicles.

Vermeulen LMP, Brans T, Samal SK, Dubruel P, Demeester J, De Smedt SC, Remaut K, Braeckmans K.

ACS Nano. 2018 Mar 27;12(3):2332-2345. doi: 10.1021/acsnano.7b07583. Epub 2018 Mar 9.

PMID:
29505236
25.

Quantifying the Average Number of Nucleic Acid Therapeutics per Nanocarrier by Single Particle Tracking Microscopy.

Zagato E, Vermeulen L, Dewitte H, Van Imschoot G, Vandenbroucke RE, Demeester J, De Smedt SC, Neyts K, Remaut K, Braeckmans K.

Mol Pharm. 2018 Mar 5;15(3):1142-1149. doi: 10.1021/acs.molpharmaceut.7b00999. Epub 2018 Feb 19.

PMID:
29433310
26.

Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models.

Linnekamp JF, Hooff SRV, Prasetyanti PR, Kandimalla R, Buikhuisen JY, Fessler E, Ramesh P, Lee KAST, Bochove GGW, de Jong JH, Cameron K, Leersum RV, Rodermond HM, Franitza M, Nürnberg P, Mangiapane LR, Wang X, Clevers H, Vermeulen L, Stassi G, Medema JP.

Cell Death Differ. 2018 Mar;25(3):616-633. doi: 10.1038/s41418-017-0011-5. Epub 2018 Jan 5.

27.

ASHP Foundation Pharmacy Forecast 2018: Strategic Planning Advice for Pharmacy Departments in Hospitals and Health Systems.

Vermeulen LC, Kolesar J, Crismon ML, Flynn AJ, Stevenson JG, Almeter PJ, Heath WM, Short GT, Enright SM, Ploetz P, Swarthout MD, Zellmer WA, Saenz R, Devereaux DS, Zilz DA, Hoffman JM, Evans WE, Knoer SJ, Ray MD.

Am J Health Syst Pharm. 2018 Jan 15;75(2):23-54. doi: 10.2146/sp180001. Epub 2017 Nov 20. Review. No abstract available.

28.

Scleral Lenses Reduce the Need for Corneal Transplants in Severe Keratoconus.

Koppen C, Kreps EO, Anthonissen L, Van Hoey M, Dhubhghaill SN, Vermeulen L.

Am J Ophthalmol. 2018 Jan;185:43-47. doi: 10.1016/j.ajo.2017.10.022. Epub 2017 Nov 16.

29.

Immunogenomic Classification of Colorectal Cancer and Therapeutic Implications.

Roelands J, Kuppen PJK, Vermeulen L, Maccalli C, Decock J, Wang E, Marincola FM, Bedognetti D, Hendrickx W.

Int J Mol Sci. 2017 Oct 24;18(10). pii: E2229. doi: 10.3390/ijms18102229. Review.

30.

Intelligent dynamic clinical checklists improved checklist compliance in the intensive care unit.

De Bie AJR, Nan S, Vermeulen LRE, Van Gorp PME, Bouwman RA, Bindels AJGH, Korsten HHM.

Br J Anaesth. 2017 Aug 1;119(2):231-238. doi: 10.1093/bja/aex129.

31.

Neoadjuvant chemotherapy affects molecular classification of colorectal tumors.

Trumpi K, Ubink I, Trinh A, Djafarihamedani M, Jongen JM, Govaert KM, Elias SG, van Hooff SR, Medema JP, Lacle MM, Vermeulen L, Borel Rinkes IHM, Kranenburg O.

Oncogenesis. 2017 Jul 10;6(7):e357. doi: 10.1038/oncsis.2017.48.

32.

Stem Cells: All that Is Solid Melts into Air.

van der Heijden M, Vermeulen L.

Cell Stem Cell. 2017 Jul 6;21(1):5-7. doi: 10.1016/j.stem.2017.06.009. Review.

33.

Global Cryptosporidium Loads from Livestock Manure.

Vermeulen LC, Benders J, Medema G, Hofstra N.

Environ Sci Technol. 2017 Aug 1;51(15):8663-8671. doi: 10.1021/acs.est.7b00452. Epub 2017 Jul 11.

34.

National trends in prescription drug expenditures and projections for 2017.

Schumock GT, Li EC, Wiest MD, Suda KJ, Stubbings J, Matusiak LM, Hunkler RJ, Vermeulen LC.

Am J Health Syst Pharm. 2017 Aug 1;74(15):1158-1173. doi: 10.2146/ajhp170164. Epub 2017 May 22.

PMID:
28533252
35.

Palliative care for people with dementia in the terminal phase: a mixed-methods qualitative study to inform service development.

van der Steen JT, Lemos Dekker N, Gijsberts MHE, Vermeulen LH, Mahler MM, The BA.

BMC Palliat Care. 2017 Apr 28;16(1):28. doi: 10.1186/s12904-017-0201-4.

36.

Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study.

Domingo E, Freeman-Mills L, Rayner E, Glaire M, Briggs S, Vermeulen L, Fessler E, Medema JP, Boot A, Morreau H, van Wezel T, Liefers GJ, Lothe RA, Danielsen SA, Sveen A, Nesbakken A, Zlobec I, Lugli A, Koelzer VH, Berger MD, Castellví-Bel S, Muñoz J; Epicolon consortium, de Bruyn M, Nijman HW, Novelli M, Lawson K, Oukrif D, Frangou E, Dutton P, Tejpar S, Delorenzi M, Kerr R, Kerr D, Tomlinson I, Church DN.

Lancet Gastroenterol Hepatol. 2016 Nov;1(3):207-216. doi: 10.1016/S2468-1253(16)30014-0. Epub 2016 Jul 20.

PMID:
28404093
37.

Molecular subtypes in cancers of the gastrointestinal tract.

Bijlsma MF, Sadanandam A, Tan P, Vermeulen L.

Nat Rev Gastroenterol Hepatol. 2017 Jun;14(6):333-342. doi: 10.1038/nrgastro.2017.33. Epub 2017 Apr 12. Review.

PMID:
28400627
38.

Transcending borders, surpassing boundaries.

Vermeulen LC.

Am J Health Syst Pharm. 2017 Apr 15;74(8):593-597. doi: 10.2146/ajhp161024. No abstract available.

PMID:
28389459
39.

Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer.

Dienstmann R, Vermeulen L, Guinney J, Kopetz S, Tejpar S, Tabernero J.

Nat Rev Cancer. 2017 Mar 23;17(4):268. doi: 10.1038/nrc.2017.24. No abstract available.

PMID:
28332502
40.

Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition.

Ebbing EA, Steins A, Fessler E, Stathi P, Lesterhuis WJ, Krishnadath KK, Vermeulen L, Medema JP, Bijlsma MF, van Laarhoven HWM.

Gastroenterology. 2017 Jul;153(1):63-76.e14. doi: 10.1053/j.gastro.2017.03.004. Epub 2017 Mar 9.

PMID:
28286209
41.

CFTR is a tumor suppressor gene in murine and human intestinal cancer.

Than BLN, Linnekamp JF, Starr TK, Largaespada DA, Rod A, Zhang Y, Bruner V, Abrahante J, Schumann A, Luczak T, Walter J, Niemczyk A, O'Sullivan MG, Medema JP, Fijneman RJA, Meijer GA, Van den Broek E, Hodges CA, Scott PM, Vermeulen L, Cormier RT.

Oncogene. 2017 Jun 15;36(24):3504. doi: 10.1038/onc.2017.3. Epub 2017 Feb 13.

PMID:
28192405
42.

Balancing signals in the intestinal niche.

van Neerven SM, Vermeulen L.

EMBO J. 2017 Feb 15;36(4):389-391. doi: 10.15252/embj.201796431. Epub 2017 Feb 3. No abstract available.

43.

Cancer stem cells don't waste their time cleaning-low proteasome activity, a marker for cancer stem cell function.

Lenos KJ, Vermeulen L.

Ann Transl Med. 2016 Dec;4(24):519. doi: 10.21037/atm.2016.11.81.

44.

Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer.

Dienstmann R, Vermeulen L, Guinney J, Kopetz S, Tejpar S, Tabernero J.

Nat Rev Cancer. 2017 Feb;17(2):79-92. doi: 10.1038/nrc.2016.126. Epub 2017 Jan 4. Review. Erratum in: Nat Rev Cancer. 2017 Mar 23;17 (4):268.

PMID:
28050011
45.

The Rising Cost of Prescription Drugs: Causes and Solutions.

Schumock GT, Vermeulen LC.

Pharmacotherapy. 2017 Jan;37(1):9-11. doi: 10.1002/phar.1873. Epub 2016 Dec 9. No abstract available.

PMID:
27943363
46.

From tumour heterogeneity to advances in precision treatment of colorectal cancer.

Punt CJ, Koopman M, Vermeulen L.

Nat Rev Clin Oncol. 2017 Apr;14(4):235-246. doi: 10.1038/nrclinonc.2016.171. Epub 2016 Dec 6. Review.

PMID:
27922044
47.

Sire line of pigs affects weaning weight, growth performance, and carcass characteristics of offspring.

Vermeulen L, Van Beirendonck S, Bulens A, Van Thielen J, Driessen B.

J Anim Sci. 2016 Oct;94(10):4360-4368. doi: 10.2527/jas.2016-0591.

PMID:
27898873
48.

Loss of KCNQ1 expression in stage II and stage III colon cancer is a strong prognostic factor for disease recurrence.

den Uil SH, Coupé VM, Linnekamp JF, van den Broek E, Goos JA, Delis-van Diemen PM, Belt EJ, van Grieken NC, Scott PM, Vermeulen L, Medema JP, Bril H, Stockmann HB, Cormier RT, Meijer GA, Fijneman RJ.

Br J Cancer. 2016 Dec 6;115(12):1565-1574. doi: 10.1038/bjc.2016.376. Epub 2016 Nov 17.

49.

Impacts of population growth, urbanisation and sanitation changes on global human Cryptosporidium emissions to surface water.

Hofstra N, Vermeulen LC.

Int J Hyg Environ Health. 2016 Oct;219(7 Pt A):599-605. doi: 10.1016/j.ijheh.2016.06.005. Epub 2016 Jun 15.

PMID:
27358259
50.

The Use of Targeted Therapies for Precision Medicine in Oncology.

White Al-Habeeb N, Kulasingam V, Diamandis EP, Yousef GM, Tsongalis GJ, Vermeulen L, Zhu Z, Kamel-Reid S.

Clin Chem. 2016 Dec;62(12):1556-1564. Epub 2016 Sep 27. No abstract available.

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