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Items: 23

1.

Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin.

Kim DE, Dollé MET, Vermeij WP, Gyenis A, Vogel K, Hoeijmakers JHJ, Wiley CD, Davalos AR, Hasty P, Desprez PY, Campisi J.

Aging Cell. 2019 Nov 18:e13072. doi: 10.1111/acel.13072. [Epub ahead of print]

2.

DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering.

Milanese C, Bombardieri CR, Sepe S, Barnhoorn S, Payán-Goméz C, Caruso D, Audano M, Pedretti S, Vermeij WP, Brandt RMC, Gyenis A, Wamelink MM, de Wit AS, Janssens RC, Leen R, van Kuilenburg ABP, Mitro N, Hoeijmakers JHJ, Mastroberardino PG.

Nat Commun. 2019 Oct 25;10(1):4887. doi: 10.1038/s41467-019-12640-5.

3.

Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling.

Alyodawi K, Vermeij WP, Omairi S, Kretz O, Hopkinson M, Solagna F, Joch B, Brandt RMC, Barnhoorn S, van Vliet N, Ridwan Y, Essers J, Mitchell R, Morash T, Pasternack A, Ritvos O, Matsakas A, Collins-Hooper H, Huber TB, Hoeijmakers JHJ, Patel K.

J Cachexia Sarcopenia Muscle. 2019 Jun;10(3):662-686. doi: 10.1002/jcsm.12404. Epub 2019 Mar 27.

4.

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1 -/Δ7 mice.

van der Lugt B, van Beek AA, Aalvink S, Meijer B, Sovran B, Vermeij WP, Brandt RMC, de Vos WM, Savelkoul HFJ, Steegenga WT, Belzer C.

Immun Ageing. 2019 Mar 8;16:6. doi: 10.1186/s12979-019-0145-z. eCollection 2019.

5.

Vitamin E Supplementation Reduces Cellular Loss in the Brain of a Premature Aging Mouse Model.

La Fata G, van Vliet N, Barnhoorn S, Brandt RMC, Etheve S, Chenal E, Grunenwald C, Seifert N, Weber P, Hoeijmakers JHJ, Mohajeri MH, Vermeij WP.

J Prev Alzheimers Dis. 2017;4(4):226-235. doi: 10.14283/jpad.2017.30.

6.

Dietary restriction but not angiotensin II type 1 receptor blockade improves DNA damage-related vasodilator dysfunction in rapidly aging Ercc1Δ/- mice.

Wu H, van Thiel BS, Bautista-Niño PK, Reiling E, Durik M, Leijten FPJ, Ridwan Y, Brandt RMC, van Steeg H, Dollé MET, Vermeij WP, Hoeijmakers JHJ, Essers J, van der Pluijm I, Danser AHJ, Roks AJM.

Clin Sci (Lond). 2017 Jul 13;131(15):1941-1953. doi: 10.1042/CS20170026. Print 2017 Aug 1.

PMID:
28620011
7.

Cellular senescence drives age-dependent hepatic steatosis.

Ogrodnik M, Miwa S, Tchkonia T, Tiniakos D, Wilson CL, Lahat A, Day CP, Burt A, Palmer A, Anstee QM, Grellscheid SN, Hoeijmakers JHJ, Barnhoorn S, Mann DA, Bird TG, Vermeij WP, Kirkland JL, Passos JF, von Zglinicki T, Jurk D.

Nat Commun. 2017 Jun 13;8:15691. doi: 10.1038/ncomms15691.

8.

Supplementation with Lactobacillus plantarum WCFS1 Prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1-/Δ7 Mice.

van Beek AA, Sovran B, Hugenholtz F, Meijer B, Hoogerland JA, Mihailova V, van der Ploeg C, Belzer C, Boekschoten MV, Hoeijmakers JH, Vermeij WP, de Vos P, Wells JM, Leenen PJ, Nicoletti C, Hendriks RW, Savelkoul HF.

Front Immunol. 2016 Oct 7;7:408. eCollection 2016.

9.

Menopause: Genome stability as new paradigm.

Laven JSE, Visser JA, Uitterlinden AG, Vermeij WP, Hoeijmakers JHJ.

Maturitas. 2016 Oct;92:15-23. doi: 10.1016/j.maturitas.2016.07.006. Epub 2016 Jul 9. Review.

PMID:
27621233
10.

Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice.

Vermeij WP, Dollé ME, Reiling E, Jaarsma D, Payan-Gomez C, Bombardieri CR, Wu H, Roks AJ, Botter SM, van der Eerden BC, Youssef SA, Kuiper RV, Nagarajah B, van Oostrom CT, Brandt RM, Barnhoorn S, Imholz S, Pennings JL, de Bruin A, Gyenis Á, Pothof J, Vijg J, van Steeg H, Hoeijmakers JH.

Nature. 2016 Sep 15;537(7620):427-431. doi: 10.1038/nature19329. Epub 2016 Aug 24.

11.

Frontline Science: Tryptophan restriction arrests B cell development and enhances microbial diversity in WT and prematurely aging Ercc1-/Δ7 mice.

van Beek AA, Hugenholtz F, Meijer B, Sovran B, Perdijk O, Vermeij WP, Brandt RM, Barnhoorn S, Hoeijmakers JH, de Vos P, Leenen PJ, Hendriks RW, Savelkoul HF.

J Leukoc Biol. 2017 Apr;101(4):811-821. doi: 10.1189/jlb.1HI0216-062RR. Epub 2016 Jul 14.

12.

Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging.

Visser WE, Bombardieri CR, Zevenbergen C, Barnhoorn S, Ottaviani A, van der Pluijm I, Brandt R, Kaptein E, van Heerebeek R, van Toor H, Garinis GA, Peeters RP, Medici M, van Ham W, Vermeij WP, de Waard MC, de Krijger RR, Boelen A, Kwakkel J, Kopchick JJ, List EO, Melis JP, Darras VM, Dollé ME, van der Horst GT, Hoeijmakers JH, Visser TJ.

PLoS One. 2016 Mar 8;11(3):e0149941. doi: 10.1371/journal.pone.0149941. eCollection 2016.

13.

Genome Integrity in Aging: Human Syndromes, Mouse Models, and Therapeutic Options.

Vermeij WP, Hoeijmakers JH, Pothof J.

Annu Rev Pharmacol Toxicol. 2016;56:427-45. doi: 10.1146/annurev-pharmtox-010814-124316. Epub 2015 Oct 28. Review.

PMID:
26514200
14.

Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency.

Barnhoorn S, Uittenboogaard LM, Jaarsma D, Vermeij WP, Tresini M, Weymaere M, Menoni H, Brandt RM, de Waard MC, Botter SM, Sarker AH, Jaspers NG, van der Horst GT, Cooper PK, Hoeijmakers JH, van der Pluijm I.

PLoS Genet. 2014 Oct 9;10(10):e1004686. doi: 10.1371/journal.pgen.1004686. eCollection 2014 Oct.

15.

Aging: not all DNA damage is equal.

Vermeij WP, Hoeijmakers JH, Pothof J.

Curr Opin Genet Dev. 2014 Jun;26:124-30. doi: 10.1016/j.gde.2014.06.006. Epub 2014 Sep 15. Review.

PMID:
25222498
16.

Reactive oxygen species (ROS) protection via cysteine oxidation in the epidermal cornified cell envelope.

Vermeij WP, Backendorf C.

Methods Mol Biol. 2014;1195:157-69. doi: 10.1007/7651_2013_51.

PMID:
24281873
17.

Spatio-temporal analysis of molecular determinants of neuronal degeneration in the aging mouse cerebellum.

de Graaf EL, Vermeij WP, de Waard MC, Rijksen Y, van der Pluijm I, Hoogenraad CC, Hoeijmakers JH, Altelaar AF, Heck AJ.

Mol Cell Proteomics. 2013 May;12(5):1350-62. doi: 10.1074/mcp.M112.024950. Epub 2013 Feb 11.

18.

Proteomic identification of in vivo interactors reveals novel function of skin cornification proteins.

Vermeij WP, Florea BI, Isenia S, Alia A, Brouwer J, Backendorf C.

J Proteome Res. 2012 Jun 1;11(6):3068-76. doi: 10.1021/pr300310b. Epub 2012 May 11.

PMID:
22519520
19.

ROS quenching potential of the epidermal cornified cell envelope.

Vermeij WP, Alia A, Backendorf C.

J Invest Dermatol. 2011 Jul;131(7):1435-41. doi: 10.1038/jid.2010.433. Epub 2011 Jan 20.

20.

Skin cornification proteins provide global link between ROS detoxification and cell migration during wound healing.

Vermeij WP, Backendorf C.

PLoS One. 2010 Aug 3;5(8):e11957. doi: 10.1371/journal.pone.0011957.

21.

Selective DNA damage responses in murine Xpa-/-, Xpc-/- and Csb-/- keratinocyte cultures.

Stout GJ, Oosten Mv, Acherrat FZ, Wit Jd, Vermeij WP, Mullenders LH, Gruijl FR, Backendorf C.

DNA Repair (Amst). 2005 Nov 21;4(11):1337-44. Epub 2005 Sep 22.

PMID:
16182614
22.

RT-PCR analysis of p73 splice variants, ease or tease?

Niemantsverdriet M, Vermeij WP, Backendorf C.

Leukemia. 2005 Sep;19(9):1685-6. No abstract available.

PMID:
16034465
23.

Distinct functional interactions of human Skn-1 isoforms with Ese-1 during keratinocyte terminal differentiation.

Cabral A, Fischer DF, Vermeij WP, Backendorf C.

J Biol Chem. 2003 May 16;278(20):17792-9. Epub 2003 Mar 6.

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