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Items: 1 to 50 of 421


Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer.

Zhu Q, Hoong N, Aslanian A, Hara T, Benner C, Heinz S, Miga KH, Ke E, Verma S, Soroczynski J, Yates JR 3rd, Hunter T, Verma IM.

Mol Cell. 2018 Jun 7;70(5):842-853.e7. doi: 10.1016/j.molcel.2018.04.023. Epub 2018 May 31.


Autologous and Heterologous Cell Therapy for Hemophilia B toward Functional Restoration of Factor IX.

Ramaswamy S, Tonnu N, Menon T, Lewis BM, Green KT, Wampler D, Monahan PE, Verma IM.

Cell Rep. 2018 May 1;23(5):1565-1580. doi: 10.1016/j.celrep.2018.03.121.


Glioblastoma Model Using Human Cerebral Organoids.

Ogawa J, Pao GM, Shokhirev MN, Verma IM.

Cell Rep. 2018 Apr 24;23(4):1220-1229. doi: 10.1016/j.celrep.2018.03.105.


Targeting CREB Pathway Suppresses Small Cell Lung Cancer.

Xia Y, Zhan C, Feng M, Leblanc M, Ke E, Yeddula N, Verma IM.

Mol Cancer Res. 2018 May;16(5):825-832. doi: 10.1158/1541-7786.MCR-17-0576. Epub 2018 Mar 9.


Transparency in authors' contributions and responsibilities to promote integrity in scientific publication.

McNutt MK, Bradford M, Drazen JM, Hanson B, Howard B, Jamieson KH, Kiermer V, Marcus E, Pope BK, Schekman R, Swaminathan S, Stang PJ, Verma IM.

Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2557-2560. doi: 10.1073/pnas.1715374115. Epub 2018 Feb 27.


EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis.

Yang W, Xia Y, Cao Y, Zheng Y, Bu W, Zhang L, You MJ, Koh MY, Cote G, Aldape K, Li Y, Verma IM, Chiao PJ, Lu Z.

Mol Cell. 2018 Jan 18;69(2):347. doi: 10.1016/j.molcel.2017.12.034. No abstract available.


Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence.

Sulli G, Rommel A, Wang X, Kolar MJ, Puca F, Saghatelian A, Plikus MV, Verma IM, Panda S.

Nature. 2018 Jan 18;553(7688):351-355. doi: 10.1038/nature25170. Epub 2018 Jan 10.


Preprint servers facilitate scientific discourse.

Verma IM.

Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):12630. doi: 10.1073/pnas.1716857114. Epub 2017 Oct 19. No abstract available.


Dovitinib enhances temozolomide efficacy in glioblastoma cells.

Thanasupawat T, Natarajan S, Rommel A, Glogowska A, Bergen H, Krcek J, Pitz M, Beiko J, Krawitz S, Verma IM, Ghavami S, Klonisch T, Hombach-Klonisch S.

Mol Oncol. 2017 Aug;11(8):1078-1098. doi: 10.1002/1878-0261.12076. Epub 2017 Jun 5.


Systemic delivery of factor IX messenger RNA for protein replacement therapy.

Ramaswamy S, Tonnu N, Tachikawa K, Limphong P, Vega JB, Karmali PP, Chivukula P, Verma IM.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):E1941-E1950. doi: 10.1073/pnas.1619653114. Epub 2017 Feb 15.


Celebrating our 20th digital anniversary.

Verma IM.

Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):3-6. doi: 10.1073/pnas.1619741114. Epub 2016 Dec 20. No abstract available.


Structural Basis for the Activation of IKK1/α.

Polley S, Passos DO, Huang DB, Mulero MC, Mazumder A, Biswas T, Verma IM, Lyumkis D, Ghosh G.

Cell Rep. 2016 Nov 15;17(8):1907-1914. doi: 10.1016/j.celrep.2016.10.067.


Lentiviral vectors, two decades later.

Naldini L, Trono D, Verma IM.

Science. 2016 Sep 9;353(6304):1101-2. doi: 10.1126/science.aah6192. No abstract available.


PNAS at 101: Heading into the next century.

Verma IM.

Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):3702-3. doi: 10.1073/pnas.1602165113. Epub 2016 Mar 1. No abstract available.


Establishment of human iPSC-based models for the study and targeting of glioma initiating cells.

Sancho-Martinez I, Nivet E, Xia Y, Hishida T, Aguirre A, Ocampo A, Ma L, Morey R, Krause MN, Zembrzycki A, Ansorge O, Vazquez-Ferrer E, Dubova I, Reddy P, Lam D, Hishida Y, Wu MZ, Esteban CR, O'Leary D, Wahl GM, Verma IM, Laurent LC, Izpisua Belmonte JC.

Nat Commun. 2016 Feb 22;7:10743. doi: 10.1038/ncomms10743.


Spatially- and temporally-controlled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation.

Hirbe AC, Dahiya S, Friedmann-Morvinski D, Verma IM, Clapp DW, Gutmann DH.

Oncotarget. 2016 Feb 16;7(7):7403-14. doi: 10.18632/oncotarget.7232.


Targeting NF-κB in glioblastoma: A therapeutic approach.

Friedmann-Morvinski D, Narasimamurthy R, Xia Y, Myskiw C, Soda Y, Verma IM.

Sci Adv. 2016 Jan 8;2(1):e1501292. doi: 10.1126/sciadv.1501292. eCollection 2016 Jan.


Antiapoptotic Role for Lifeguard in T Cell Mediated Immune Response.

Hurtado de Mendoza T, Liu F, Verma IM.

PLoS One. 2015 Nov 13;10(11):e0142161. doi: 10.1371/journal.pone.0142161. eCollection 2015.


Screening for tumor suppressors: Loss of ephrin receptor A2 cooperates with oncogenic KRas in promoting lung adenocarcinoma.

Yeddula N, Xia Y, Ke E, Beumer J, Verma IM.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6476-85. doi: 10.1073/pnas.1520110112. Epub 2015 Nov 5.


Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs.

Firth AL, Menon T, Parker GS, Qualls SJ, Lewis BM, Ke E, Dargitz CT, Wright R, Khanna A, Gage FH, Verma IM.

Cell Rep. 2015 Sep 1;12(9):1385-90. doi: 10.1016/j.celrep.2015.07.062. Epub 2015 Aug 20.


Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer.

Font-Burgada J, Shalapour S, Ramaswamy S, Hsueh B, Rossell D, Umemura A, Taniguchi K, Nakagawa H, Valasek MA, Ye L, Kopp JL, Sander M, Carter H, Deisseroth K, Verma IM, Karin M.

Cell. 2015 Aug 13;162(4):766-79. doi: 10.1016/j.cell.2015.07.026.


Impact, not impact factor.

Verma IM.

Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):7875-6. doi: 10.1073/pnas.1509912112. Epub 2015 Jun 15. No abstract available.


Identification of therapeutic targets for glioblastoma by network analysis.

Friedmann-Morvinski D, Bhargava V, Gupta S, Verma IM, Subramaniam S.

Oncogene. 2016 Feb 4;35(5):608-20. doi: 10.1038/onc.2015.119. Epub 2015 May 11.


Lentiviral vectors for retrograde delivery of recombinases and transactivators.

Wickersham IR, Sullivan HA, Pao GM, Hamanaka H, Goosens KA, Verma IM, Seung HS.

Cold Spring Harb Protoc. 2015 Apr 1;2015(4):368-74. doi: 10.1101/pdb.prot075879.


Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.

Xia Y, Yeddula N, Leblanc M, Ke E, Zhang Y, Oldfield E, Shaw RJ, Verma IM.

Nat Cell Biol. 2015 Apr;17(4):532. doi: 10.1038/ncb3145. No abstract available.


Lymphoid regeneration from gene-corrected SCID-X1 subject-derived iPSCs.

Menon T, Firth AL, Scripture-Adams DD, Galic Z, Qualls SJ, Gilmore WB, Ke E, Singer O, Anderson LS, Bornzin AR, Alexander IE, Zack JA, Verma IM.

Cell Stem Cell. 2015 Apr 2;16(4):367-72. doi: 10.1016/j.stem.2015.02.005. Epub 2015 Mar 12.


A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin.

Xia Y, Liu YL, Xie Y, Zhu W, Guerra F, Shen S, Yeddula N, Fischer W, Low W, Zhou X, Zhang Y, Oldfield E, Verma IM.

Sci Transl Med. 2014 Nov 19;6(263):263ra161. doi: 10.1126/scitranslmed.3010382.


Simplifying the Direct Submission process.

Verma IM.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14311. doi: 10.1073/pnas.1417688111. Epub 2014 Sep 22. No abstract available.


Editorial expression of concern: Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules.

Verma IM.

Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13241. doi: 10.1073/pnas.1415649111. Epub 2014 Sep 2. No abstract available.


NF-κB, an active player in human cancers.

Xia Y, Shen S, Verma IM.

Cancer Immunol Res. 2014 Sep;2(9):823-30. doi: 10.1158/2326-6066.CIR-14-0112. Review.


Astrocytes contribute to gamma oscillations and recognition memory.

Lee HS, Ghetti A, Pinto-Duarte A, Wang X, Dziewczapolski G, Galimi F, Huitron-Resendiz S, Piña-Crespo JC, Roberts AJ, Verma IM, Sejnowski TJ, Heinemann SF.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3343-52. doi: 10.1073/pnas.1410893111. Epub 2014 Jul 28.


Editorial expression of concern: Experimental evidence of massive-scale emotional contagion through social networks.

Verma IM.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10779. doi: 10.1073/pnas.1412469111. Epub 2014 Jul 3. No abstract available.


Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells.

Firth AL, Dargitz CT, Qualls SJ, Menon T, Wright R, Singer O, Gage FH, Khanna A, Verma IM.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):E1723-30. doi: 10.1073/pnas.1403470111. Epub 2014 Mar 24.


Role of BRCA1 in brain development.

Pao GM, Zhu Q, Perez-Garcia CG, Chou SJ, Suh H, Gage FH, O'Leary DD, Verma IM.

Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):E1240-8. doi: 10.1073/pnas.1400783111. Epub 2014 Mar 17.


Dedifferentiation and reprogramming: origins of cancer stem cells.

Friedmann-Morvinski D, Verma IM.

EMBO Rep. 2014 Mar;15(3):244-53. doi: 10.1002/embr.201338254. Epub 2014 Feb 14. Review.


Medicine. Gene therapy that works.

Verma IM.

Science. 2013 Aug 23;341(6148):853-5. doi: 10.1126/science.1242551. No abstract available.


A structural basis for IκB kinase 2 activation via oligomerization-dependent trans auto-phosphorylation.

Polley S, Huang DB, Hauenstein AV, Fusco AJ, Zhong X, Vu D, Schröfelbauer B, Kim Y, Hoffmann A, Verma IM, Ghosh G, Huxford T.

PLoS Biol. 2013;11(6):e1001581. doi: 10.1371/journal.pbio.1001581. Epub 2013 Jun 11.


Mechanisms of neovascularization and resistance to anti-angiogenic therapies in glioblastoma multiforme.

Soda Y, Myskiw C, Rommel A, Verma IM.

J Mol Med (Berl). 2013 Apr;91(4):439-48. doi: 10.1007/s00109-013-1019-z. Epub 2013 Mar 20. Review.


PNAS introduces new magazine section.

Verma IM, Harris DJ.

Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2427. doi: 10.1073/pnas.1300186110. Epub 2013 Jan 30. No abstract available. Erratum in: Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4148. Verman, Inder M [corrected to Verma, Inder M].


Light-sheet Bayesian microscopy enables deep-cell super-resolution imaging of heterochromatin in live human embryonic stem cells.

Hu YS, Zhu Q, Elkins K, Tse K, Li Y, Fitzpatrick JA, Verma IM, Cang H.

Opt Nanoscopy. 2013;2(1). pii: 7. Epub 2013 Nov 20.


The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle.

Holland AJ, Fachinetti D, Zhu Q, Bauer M, Verma IM, Nigg EA, Cleveland DW.

Genes Dev. 2012 Dec 15;26(24):2684-9. doi: 10.1101/gad.207027.112.


EGFR-induced and PKCε monoubiquitylation-dependent NF-κB activation upregulates PKM2 expression and promotes tumorigenesis.

Yang W, Xia Y, Cao Y, Zheng Y, Bu W, Zhang L, You MJ, Koh MY, Cote G, Aldape K, Li Y, Verma IM, Chiao PJ, Lu Z.

Mol Cell. 2012 Dec 14;48(5):771-84. doi: 10.1016/j.molcel.2012.09.028. Epub 2012 Nov 1. Erratum in: Mol Cell. 2018 Jan 18;69(2):347.


Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice.

Friedmann-Morvinski D, Bushong EA, Ke E, Soda Y, Marumoto T, Singer O, Ellisman MH, Verma IM.

Science. 2012 Nov 23;338(6110):1080-4. doi: 10.1126/science.1226929. Epub 2012 Oct 18.


PNAS Plus: Refining a successful experiment.

Verma IM.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13469. doi: 10.1073/pnas.1212313109. Epub 2012 Aug 7. No abstract available.


Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines.

Narasimamurthy R, Hatori M, Nayak SK, Liu F, Panda S, Verma IM.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12662-7. doi: 10.1073/pnas.1209965109. Epub 2012 Jul 9.


Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis.

Holland AJ, Fachinetti D, Da Cruz S, Zhu Q, Vitre B, Lince-Faria M, Chen D, Parish N, Verma IM, Bettencourt-Dias M, Cleveland DW.

Mol Biol Cell. 2012 May;23(10):1838-45. doi: 10.1091/mbc.E11-12-1043. Epub 2012 Mar 28.


Renato Dulbecco (1914-2012).

Verma IM.

Nature. 2012 Mar 21;483(7390):408. doi: 10.1038/483408a. No abstract available.


IKK biology.

Liu F, Xia Y, Parker AS, Verma IM.

Immunol Rev. 2012 Mar;246(1):239-53. doi: 10.1111/j.1600-065X.2012.01107.x. Review.


Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.

Xia Y, Yeddula N, Leblanc M, Ke E, Zhang Y, Oldfield E, Shaw RJ, Verma IM.

Nat Cell Biol. 2012 Feb 12;14(3):257-65. doi: 10.1038/ncb2428. Erratum in: Nat Cell Biol. 2015 Apr;17(4):532.


QnAs with Inder M. Verma. Interview by Prashant Nair.

Verma IM.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20300. doi: 10.1073/pnas.1118850109. Epub 2011 Nov 30. No abstract available.

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