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Items: 1 to 50 of 124

1.

Integrative analysis of dysregulated microRNAs and mRNAs in multiple recurrent synchronized renal tumors from patients with von Hippel-Lindau disease.

Gattolliat CH, Couvé S, Meurice G, Oréar C, Droin N, Chiquet M, Ferlicot S, Verkarre V, Vasiliu V, Molinié V, Méjean A, Dessen P, Giraud S, Bressac-De-Paillerets B, Gardie B, Tean Teh B, Richard S, Gad S.

Int J Oncol. 2018 Oct;53(4):1455-1468. doi: 10.3892/ijo.2018.4490. Epub 2018 Jul 19.

2.

Sunitinib Prior to Planned Nephrectomy in Metastatic Renal Cell Carcinoma: Angiogenesis Biomarkers Predict Clinical Outcome in the Prospective Phase II PREINSUT Trial.

Mauge L, Mejean A, Fournier L, Pereira H, Etienne-Grimaldi MC, Levionnois E, Caty A, Abadie-Lacourtoisie S, Culine S, Le Moulec S, Linassier C, Théodore C, Ravaud A, Albiges L, Grine A, Tartour E, Milano G, Gille AS, Verkarre V, Helley D, Oudard S; PREINSUT study group.

Clin Cancer Res. 2018 Jul 30. doi: 10.1158/1078-0432.CCR-18-1045. [Epub ahead of print]

PMID:
30061359
3.

Contemporary assessment of the correlation between Bosniak classification and histological characteristics of surgically removed atypical renal cysts (UroCCR-12 study).

Nouhaud FX, Bernhard JC, Bigot P, Khene ZE, Audenet F, Lang H, Bergerat S, Fraisse G, Grenier N, Cornelis F, Nedelcu C, Béjar S, Fromont-Hankard G, Allory Y, Lindner V, Verkarre V, Daniel L, Yacoub M, Correas JM, Méjean A, Rioux-Leclercq N, Bensalah K.

World J Urol. 2018 Oct;36(10):1643-1649. doi: 10.1007/s00345-018-2307-6. Epub 2018 May 5.

PMID:
29730837
4.

Nephron sparing surgery in tumours greater than 7cm.

de Saint Aubert N, Audenet F, Mccaig F, Delavaud C, Verkarre V, Le Guilchet T, Dariane C, Pettenati C, Slaoui H, Mejean A, Timsit MO.

Prog Urol. 2018 May;28(6):336-343. doi: 10.1016/j.purol.2018.03.009. Epub 2018 Apr 23.

PMID:
29699856
5.

Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells.

Granier C, Vinatier E, Colin E, Mandavit M, Dariane C, Verkarre V, Biard L, El Zein R, Lesaffre C, Galy-Fauroux I, Roussel H, De Guillebon E, Blanc C, Saldmann A, Badoual C, Gey A, Tartour É.

J Vis Exp. 2018 Feb 8;(132). doi: 10.3791/56606.

PMID:
29553498
6.

[Tim-3: a novel biomarker and therapeutic target in oncology].

Granier C, Gey A, Dariane C, Mejean A, Timsit MO, Blanc C, Verkarre V, Radulescu C, Fabre E, Vano Y, Oudard S, Badoual C, Tartour É.

Med Sci (Paris). 2018 Mar;34(3):231-237. doi: 10.1051/medsci/20183403011. Epub 2018 Mar 16. Review. French.

PMID:
29547109
7.

Polymorphisms in the Von Hippel-Lindau Gene Are Associated With Overall Survival in Metastatic Clear-Cell Renal-Cell Carcinoma Patients Treated With VEGFR Tyrosine Kinase Inhibitors.

Verbiest A, Lambrechts D, Van Brussel T, Couchy G, Wozniak A, Méjean A, Lerut E, Oudard S, Verkarre V, Job S, de Reynies A, Machiels JP, Patard JJ, Zucman-Rossi J, Beuselinck B.

Clin Genitourin Cancer. 2018 Aug;16(4):266-273. doi: 10.1016/j.clgc.2018.01.013. Epub 2018 Feb 5.

PMID:
29503246
8.

Simple and complex renal cysts in adults: Classification system for renal cystic masses.

Hélénon O, Crosnier A, Verkarre V, Merran S, Méjean A, Correas JM.

Diagn Interv Imaging. 2018 Apr;99(4):189-218. doi: 10.1016/j.diii.2017.10.005. Epub 2018 Feb 23.

PMID:
29482969
9.

[Sporadic kidney cancer of young subjects: Study of the clinical and pathological features of a bicentric cohort].

Cohen J, Timsit MO, Zerbib OD, Rouprêt M, Verkarre V, Comperat E, Mejean A, Bitker MO.

Prog Urol. 2018 Feb;28(2):94-106. doi: 10.1016/j.purol.2017.10.007. Epub 2017 Nov 21. French.

PMID:
29170016
10.

Pro-angiogenic gene expression is associated with better outcome on sunitinib in metastatic clear-cell renal cell carcinoma.

Beuselinck B, Verbiest A, Couchy G, Job S, de Reynies A, Meiller C, Albersen M, Verkarre V, Lerut E, Méjean A, Patard JJ, Laguerre B, Rioux-Leclercq N, Schöffski P, Oudard S, Zucman-Rossi J.

Acta Oncol. 2018 Apr;57(4):498-508. doi: 10.1080/0284186X.2017.1388927. Epub 2017 Nov 2.

PMID:
29095068
11.

Pathological heterogeneity in sporadic synchronous renal tumors: Is the histological concordance predictable?

Beaugerie A, Audenet F, Verkarre V, Delavaud C, Le Guilchet T, Hurel S, de Saint Aubert N, Correas JM, Fontaine E, Richard S, Méjean A, Timsit MO.

Urol Oncol. 2018 Jan;36(1):11.e7-11.e12. doi: 10.1016/j.urolonc.2017.09.002. Epub 2017 Oct 6.

PMID:
28993058
12.

Successful Use of Sirolimus in Children With Large Mesenteric Lymphatic Lesions.

Gastineau S, Paolella G, Talbotec C, Verkarre V, Sauvat F, Goulet O, Fraitag S, Lacaille F.

J Pediatr Gastroenterol Nutr. 2018 Jan;66(1):e24-e25. doi: 10.1097/MPG.0000000000001703. No abstract available.

PMID:
28777125
13.

Biphasic Squamoid Alveolar Renal Cell Carcinoma: 2 Cases in a Family Supporting a Continuous Spectrum With Papillary Type I Renal Cell Carcinoma.

Chartier S, Méjean A, Richard S, Thiounn N, Vasiliu V, Verkarre V.

Am J Surg Pathol. 2017 Jul;41(7):1011-1012. doi: 10.1097/PAS.0000000000000870. No abstract available.

PMID:
28498286
14.

[Quiz: Ready, study, score!]

Roussel H, Gibault L, Verkarre V, Lantuejoul S, Badoual C.

Ann Pathol. 2017 Feb;37(1):7-10. doi: 10.1016/j.annpat.2016.12.014. Epub 2017 Feb 1. French. No abstract available.

PMID:
28161002
15.

[Immunotherapy in uropathology].

Verkarre V, Roussel H, Granier C, Tartour E, Allory Y.

Ann Pathol. 2017 Feb;37(1):90-100. doi: 10.1016/j.annpat.2016.12.015. Epub 2017 Jan 19. Review. French.

PMID:
28111042
16.

Sunitinib in kidney cancer: 10 years of experience and development.

Nassif E, Thibault C, Vano Y, Fournier L, Mauge L, Verkarre V, Timsit MO, Mejean A, Tartour E, Oudard S.

Expert Rev Anticancer Ther. 2017 Feb;17(2):129-142. doi: 10.1080/14737140.2017.1272415. Epub 2016 Dec 27. Review.

PMID:
27967249
17.

Vitamin D3 Prevents Calcium-Induced Progression of Early-Stage Prostate Tumors by Counteracting TRPC6 and Calcium Sensing Receptor Upregulation.

Bernichtein S, Pigat N, Barry Delongchamps N, Boutillon F, Verkarre V, Camparo P, Reyes-Gomez E, Méjean A, Oudard SM, Lepicard EM, Viltard M, Souberbielle JC, Friedlander G, Capiod T, Goffin V.

Cancer Res. 2017 Jan 15;77(2):355-365. doi: 10.1158/0008-5472.CAN-16-0687. Epub 2016 Nov 22.

18.

Tim-3 Expression on Tumor-Infiltrating PD-1+CD8+ T Cells Correlates with Poor Clinical Outcome in Renal Cell Carcinoma.

Granier C, Dariane C, Combe P, Verkarre V, Urien S, Badoual C, Roussel H, Mandavit M, Ravel P, Sibony M, Biard L, Radulescu C, Vinatier E, Benhamouda N, Peyromaure M, Oudard S, Méjean A, Timsit MO, Gey A, Tartour E.

Cancer Res. 2017 Mar 1;77(5):1075-1082. doi: 10.1158/0008-5472.CAN-16-0274. Epub 2016 Nov 21.

19.

Unique Transcriptomic Profile of Collecting Duct Carcinomas Relative to Upper Tract Urothelial Carcinomas and other Kidney Carcinomas.

Malouf GG, Compérat E, Yao H, Mouawad R, Lindner V, Rioux-Leclercq N, Verkarre V, Leroy X, Dainese L, Classe M, Descotes JL, Barthelemy P, Yacoub M, Rouprêt M, Bernhard JC, Creighton CJ, Spano JP, Su X, Khayat D.

Sci Rep. 2016 Aug 3;6:30988. doi: 10.1038/srep30988.

20.

[Innovations in medical undergraduate pathology education: The Paris Descartes medicine faculty experience].

Just PA, Verkarre V, Mansuet-Lupo A, Rabant M, Daniliuc C, Radenen B, Harent M, Cassanelli L, Cherel É, Javaux H, Tesniere A, Terris B, Badoual C.

Ann Pathol. 2016 Aug;36(4):252-7. doi: 10.1016/j.annpat.2016.04.006. Epub 2016 Jul 27. French.

PMID:
27475003
21.

[Cancer genetic screening for patient with multiple renal tumors: What is the current practice for what results?].

Beaugerie A, Verkarre V, Audenet F, Le Guilchet T, Hurel S, Richard S, Corréas JM, Fontaine E, Méjean A, Timsit MO.

Prog Urol. 2016 Jun;26(8):442-9. doi: 10.1016/j.purol.2016.06.001. Epub 2016 Jul 26. French.

PMID:
27473786
22.

Calcified Renal Angiomyolipoma: A Case Report.

Cholet C, Eiss D, Cohen D, Verkarre V, Hélénon O.

Urology. 2016 Nov;97:e7-e8. doi: 10.1016/j.urology.2016.07.011. Epub 2016 Jul 18.

PMID:
27443470
23.

Validation of VEGFR1 rs9582036 as predictive biomarker in metastatic clear-cell renal cell carcinoma patients treated with sunitinib.

Beuselinck B, Jean-Baptiste J, Schöffski P, Couchy G, Meiller C, Rolland F, Allory Y, Joniau S, Verkarre V, Elaidi R, Lerut E, Roskams T, Patard JJ, Oudard S, Méjean A, Lambrechts D, Zucman-Rossi J.

BJU Int. 2016 Dec;118(6):890-901. doi: 10.1111/bju.13585. Epub 2016 Aug 12.

24.

Prostate cancer characteristics and outcome in renal transplant recipients: results from a contemporary single center study.

Pettenati C, Jannot AS, Hurel S, Verkarre V, Kreis H, Housset M, Legendre C, Méjean A, Timsit MO.

Clin Transplant. 2016 Aug;30(8):964-71. doi: 10.1111/ctr.12773. Epub 2016 Jul 5.

PMID:
27251769
25.

Multimodal management of primary adenocarcinoma of the female urethra: About four cases.

Deberne M, Timsit MO, Verkarre V, Eiss D, Kreps S, Dupont S, Housset M.

Cancer Radiother. 2016 May;20(3):169-75. doi: 10.1016/j.canrad.2015.11.005. Epub 2016 Apr 11.

PMID:
27080576
26.

Impact of Obliterative Portal Venopathy Associated With Human Immunodeficiency Virus.

Hollande C, Mallet V, Darbeda S, Vallet-Pichard A, Fontaine H, Verkarre V, Sogni P, Terris B, Gouya H, Pol S.

Medicine (Baltimore). 2016 Mar;95(11):e3081. doi: 10.1097/MD.0000000000003081.

27.

Comparaison des résultats de la chirurgie conservatrice vs totale dans le traitement des carcinomes à cellules rénales classés cT2.

De Saint Aubert N, Méjean A, Verkarre V, Fontaine E, Ariane M, Audenet F, Timsit M.

Prog Urol. 2015 Nov;25(13):825-6. doi: 10.1016/j.purol.2015.08.218. French. No abstract available.

PMID:
26544412
28.

RANK/OPG ratio of expression in primary clear-cell renal cell carcinoma is associated with bone metastasis and prognosis in patients treated with anti-VEGFR-TKIs.

Beuselinck B, Jean-Baptiste J, Couchy G, Job S, De Reynies A, Wolter P, Théodore C, Gravis G, Rousseau B, Albiges L, Joniau S, Verkarre V, Lerut E, Patard JJ, Schöffski P, Méjean A, Elaidi R, Oudard S, Zucman-Rossi J.

Br J Cancer. 2015 Nov 3;113(9):1313-22. doi: 10.1038/bjc.2015.352. Epub 2015 Oct 13.

29.

Le cancer de prostate du transplante rénal n'impose pas de prise en charge spécifique.

Pettenati C, Jannot A, Verkarre V, Hurel S, Fournier C, Legendre C, Mejean A, Timsit M.

Prog Urol. 2014 Nov;24(13):855. doi: 10.1016/j.purol.2014.08.161. Epub 2014 Oct 30. French. No abstract available.

PMID:
26461686
30.

Étude anatomo-clinique rétrospective d'une série de 17 cas de carcinomes rénaux à stroma leiomyomateux identifiant une association forte avec la Sclérose Tubéreuse de Bourneville.

Verkarre V, Leroy X, Sibony M, Mensah A, Timsit M, Richard S, Joly D, Malinge M, Correas J, Mejean A.

Prog Urol. 2014 Nov;24(13):835-6. doi: 10.1016/j.purol.2014.08.115. Epub 2014 Oct 30. French. No abstract available.

PMID:
26461640
31.

Tumeurs du rein multiples sporadiques : quelle concordance histologique ?

Beaugerie A, Verkarre V, Ariane M, Audenet F, Corréas J, Vasiliu V, Richard S, Méjean A, Timsit M.

Prog Urol. 2014 Nov;24(13):834. doi: 10.1016/j.purol.2014.08.112. Epub 2014 Oct 30. French. No abstract available.

PMID:
26461639
32.

Dépistage oncogénétique dans les tumeurs du rein multiples : quelle pratique ? Quels résultats ?

Beaugerie A, Verkarre V, Ariane M, Audenet F, Corréas J, Vasiliu V, Richard S, Méjean A, Timsit M.

Prog Urol. 2014 Nov;24(13):834-5. doi: 10.1016/j.purol.2014.08.113. Epub 2014 Oct 30. French. No abstract available.

PMID:
26461638
33.

Validation d'une signature de 16 gènes pour prédire la récidive après néphrectomie pour carcinome à cellules claires stade I-III.

Mejean A, Lebret T, Verkarre V, Radulescu C, Timsit M, Neuzillet Y, Koscielny S, Hemmerlé I, Guilmy S, Escudier B.

Prog Urol. 2014 Nov;24(13):833. doi: 10.1016/j.purol.2014.08.110. Epub 2014 Oct 30. French. No abstract available.

PMID:
26461636
34.

Tubulocystic renal cell carcinoma: a new radiological entity.

Cornelis F, Hélénon O, Correas JM, Lemaitre L, André M, Meuwly JY, Sengel C, Derchi L, Yacoub M, Verkarre V, Grenier N.

Eur Radiol. 2016 Apr;26(4):1108-15. doi: 10.1007/s00330-015-3923-9. Epub 2015 Jul 24. Review.

PMID:
26201293
35.

Gastrointestinal Disorder Associated with Olmesartan Mimics Autoimmune Enteropathy.

Scialom S, Malamut G, Meresse B, Guegan N, Brousse N, Verkarre V, Derrieux C, Macintyre E, Seksik P, Savoye G, Cadiot G, Vuitton L, Marthey L, Carbonnel F, Cerf-Bensussan N, Cellier C.

PLoS One. 2015 Jun 23;10(6):e0125024. doi: 10.1371/journal.pone.0125024. eCollection 2015.

36.

A 16-gene assay to predict recurrence after surgery in localised renal cell carcinoma: development and validation studies.

Rini B, Goddard A, Knezevic D, Maddala T, Zhou M, Aydin H, Campbell S, Elson P, Koscielny S, Lopatin M, Svedman C, Martini JF, Williams JA, Verkarre V, Radulescu C, Neuzillet Y, Hemmerlé I, Timsit MO, Tsiatis AC, Bonham M, Lebret T, Mejean A, Escudier B.

Lancet Oncol. 2015 Jun;16(6):676-85. doi: 10.1016/S1470-2045(15)70167-1. Epub 2015 May 12.

PMID:
25979595
37.

High milk consumption does not affect prostate tumor progression in two mouse models of benign and neoplastic lesions.

Bernichtein S, Pigat N, Capiod T, Boutillon F, Verkarre V, Camparo P, Viltard M, Méjean A, Oudard S, Souberbielle JC, Friedlander G, Goffin V.

PLoS One. 2015 May 4;10(5):e0125423. doi: 10.1371/journal.pone.0125423. eCollection 2015.

38.

Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer.

Giraldo NA, Becht E, Pagès F, Skliris G, Verkarre V, Vano Y, Mejean A, Saint-Aubert N, Lacroix L, Natario I, Lupo A, Alifano M, Damotte D, Cazes A, Triebel F, Freeman GJ, Dieu-Nosjean MC, Oudard S, Fridman WH, Sautès-Fridman C.

Clin Cancer Res. 2015 Jul 1;21(13):3031-40. doi: 10.1158/1078-0432.CCR-14-2926. Epub 2015 Feb 16.

39.

Molecular subtypes of clear cell renal cell carcinoma are associated with sunitinib response in the metastatic setting.

Beuselinck B, Job S, Becht E, Karadimou A, Verkarre V, Couchy G, Giraldo N, Rioux-Leclercq N, Molinié V, Sibony M, Elaidi R, Teghom C, Patard JJ, Méjean A, Fridman WH, Sautès-Fridman C, de Reyniès A, Oudard S, Zucman-Rossi J.

Clin Cancer Res. 2015 Mar 15;21(6):1329-39. doi: 10.1158/1078-0432.CCR-14-1128. Epub 2015 Jan 12.

40.

Double-echo gradient chemical shift MR imaging fails to differentiate minimal fat renal angiomyolipomas from other homogeneous solid renal tumors.

Ferré R, Cornelis F, Verkarre V, Eiss D, Correas JM, Grenier N, Hélénon O.

Eur J Radiol. 2015 Mar;84(3):360-365. doi: 10.1016/j.ejrad.2014.11.040. Epub 2014 Dec 15.

PMID:
25547327
41.

Renal cell tumour characteristics in patients with the Birt-Hogg-Dubé cancer susceptibility syndrome: a retrospective, multicentre study.

Benusiglio PR, Giraud S, Deveaux S, Méjean A, Correas JM, Joly D, Timsit MO, Ferlicot S, Verkarre V, Abadie C, Chauveau D, Leroux D, Avril MF, Cordier JF, Richard S; French National Cancer Institute Inherited Predisposition to Kidney Cancer Network.

Orphanet J Rare Dis. 2014 Oct 29;9:163. doi: 10.1186/s13023-014-0163-z.

42.

Renal papillary carcinoma: CT and MRI features.

Couvidat C, Eiss D, Verkarre V, Merran S, Corréas JM, Méjean A, Hélénon O.

Diagn Interv Imaging. 2014 Nov;95(11):1055-63.

43.

Human pancreas endocrine cell populations and activating ABCC8 mutations.

Busiah K, Verkarre V, Cavé H, Scharfmann R, Polak M.

Horm Res Paediatr. 2014;82(1):59-64. doi: 10.1159/000360004. Epub 2014 Jun 14.

PMID:
24941889
44.

Pulmonary alveolar proteinosis in children on La Réunion Island: a new inherited disorder?

Enaud L, Hadchouel A, Coulomb A, Berteloot L, Lacaille F, Boccon-Gibod L, Boulay V, Darcel F, Griese M, Linard M, Louha M, Renouil M, Rivière JP, Toupance B, Verkarre V, Delacourt C, de Blic J.

Orphanet J Rare Dis. 2014 Jun 14;9:85. doi: 10.1186/1750-1172-9-85.

45.

Efflux pump ABCB1 single nucleotide polymorphisms and dose reductions in patients with metastatic renal cell carcinoma treated with sunitinib.

Beuselinck B, Lambrechts D, Van Brussel T, Wolter P, Cardinaels N, Joniau S, Lerut E, Karadimou A, Couchy G, Sebe P, Ravaud A, Zerbib M, Caty A, Paridaens R, Schöffski P, Verkarre V, Berger J, Patard JJ, Zucman-Rossi J, Oudard S.

Acta Oncol. 2014 Oct;53(10):1413-22. doi: 10.3109/0284186X.2014.918276. Epub 2014 May 30.

PMID:
24874929
46.

MET is a potential target across all papillary renal cell carcinomas: result from a large molecular study of pRCC with CGH array and matching gene expression array.

Albiges L, Guegan J, Le Formal A, Verkarre V, Rioux-Leclercq N, Sibony M, Bernhard JC, Camparo P, Merabet Z, Molinie V, Allory Y, Orear C, Couvé S, Gad S, Patard JJ, Escudier B.

Clin Cancer Res. 2014 Jul 1;20(13):3411-21. doi: 10.1158/1078-0432.CCR-13-2173. Epub 2014 Mar 21.

47.

MYO5B and bile salt export pump contribute to cholestatic liver disorder in microvillous inclusion disease.

Girard M, Lacaille F, Verkarre V, Mategot R, Feldmann G, Grodet A, Sauvat F, Irtan S, Davit-Spraul A, Jacquemin E, Ruemmele F, Rainteau D, Goulet O, Colomb V, Chardot C, Henrion-Caude A, Debray D.

Hepatology. 2014 Jul;60(1):301-10. doi: 10.1002/hep.26974. Epub 2014 May 27.

PMID:
24375397
48.

Small intestinal CD4+ T-cell lymphoma is a heterogenous entity with common pathology features.

Malamut G, Meresse B, Kaltenbach S, Derrieux C, Verkarre V, Macintyre E, Ruskone-Fourmestraux A, Fabiani B, Radford-Weiss I, Brousse N, Hermine O, Cerf-Bensussan N, Cellier C.

Clin Gastroenterol Hepatol. 2014 Apr;12(4):599-608.e1. doi: 10.1016/j.cgh.2013.11.028. Epub 2013 Dec 4.

PMID:
24316103
49.

Clinicopathological characteristics of incidental prostate cancer discovered from radical cystoprostatectomy specimen: a multicenter French study.

Pignot G, Salomon L, Neuzillet Y, Masson-Lecomte A, Lebacle C, Patard JJ, Lunardi P, Rischmann P, Pasticier G, Bernhard JC, Cohen J, Timsit MO, Verkarre V, Peyronnet B, Verhoest G, Le Goux C, Zerbib M, Brecheteau F, Bigot P, Larre S, Murez T, Thuret R, Lacarriere E, Champy C, Roupret M, Comperat E, Berger J, Descazeaud A, Toledano H, Bastide C, Lavilledieu S, Avances C, Delage F, Valeri A, Molimard B, Houlgatte A, Gres P, Donnaint A, Kleinclauss F, Legal S, Doerfler A, Koutlidis N, Cormier L, Hetet JF, Colls P, Arvin-Berod A, Rambeaud JJ, Quintens H, Soulie M, Pfister C; Oncologic Committee of the French Association of Urology.

Ann Surg Oncol. 2014 Feb;21(2):684-90. doi: 10.1245/s10434-013-3340-8. Epub 2013 Oct 30.

PMID:
24170436
50.

Mucormycosis as a rare cause of severe gastrointestinal bleeding after multivisceral transplantation.

Irtan S, Lamerain M, Lesage F, Verkarre V, Bougnoux ME, Lanternier F, Zahar JR, Salvi N, Talbotec C, Lortholary O, Lacaille F, Chardot C.

Transpl Infect Dis. 2013 Dec;15(6):E235-8. doi: 10.1111/tid.12147. Epub 2013 Sep 18.

PMID:
24103142

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