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Items: 1 to 50 of 142

1.

Inhibition of histone methyltransferase EZH2 in Schistosoma mansoni in vitro by GSK343 reduces egg laying and decreases the expression of genes implicated in DNA replication and noncoding RNA metabolism.

Pereira ASA, Amaral MS, Vasconcelos EJR, Pires DS, Asif H, daSilva LF, Morales-Vicente DA, Carneiro VC, Angeli CB, Palmisano G, Fantappie MR, Pierce RJ, Setubal JC, Verjovski-Almeida S.

PLoS Negl Trop Dis. 2018 Oct 26;12(10):e0006873. doi: 10.1371/journal.pntd.0006873. eCollection 2018 Oct.

2.

Atlas of Schistosoma mansoni long non-coding RNAs and their expression correlation to protein-coding genes.

Vasconcelos EJR, Mesel VC, daSilva LF, Pires DS, Lavezzo GM, Pereira ASA, Amaral MS, Verjovski-Almeida S.

Database (Oxford). 2018 Jan 1;2018. doi: 10.1093/database/bay068.

3.

Chromatin Landscape Distinguishes the Genomic Loci of Hundreds of Androgen-Receptor-Associated LincRNAs From the Loci of Non-associated LincRNAs.

daSilva LF, Beckedorff FC, Ayupe AC, Amaral MS, Mesel V, Videira A, Reis EM, Setubal JC, Verjovski-Almeida S.

Front Genet. 2018 Apr 25;9:132. doi: 10.3389/fgene.2018.00132. eCollection 2018.

4.

Publisher Correction: Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells.

Caires-Júnior LC, Goulart E, Melo US, Araujo BHS, Alvizi L, Soares-Schanoski A, de Oliveira DF, Kobayashi GS, Griesi-Oliveira K, Musso CM, Amaral MS, daSilva LF, Astray RM, Suárez-Patiño SF, Ventini DC, da Silva SG, Yamamoto GL, Ezquina S, Naslavsky MS, Telles-Silva KA, Weinmann K, van der Linden V, van der Linden H, de Oliveira JRM, Arrais NMR, Melo A, Figueiredo T, Santos S, Meira JGC, Passos SD, de Almeida RP, Bispo AJB, Cavalheiro EA, Kalil J, Cunha-Neto E, Nakaya H, Andreata-Santos R, de Souza Ferreira LC, Verjovski-Almeida S, Ho PL, Passos-Bueno MR, Zatz M.

Nat Commun. 2018 Mar 13;9(1):1114. doi: 10.1038/s41467-018-03497-1.

5.

Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells.

Caires-Júnior LC, Goulart E, Melo US, Araujo BHS, Alvizi L, Soares-Schanoski A, de Oliveira DF, Kobayashi GS, Griesi-Oliveira K, Musso CM, Amaral MS, daSilva LF, Astray RM, Suárez-Patiño SF, Ventini DC, Gomes da Silva S, Yamamoto GL, Ezquina S, Naslavsky MS, Telles-Silva KA, Weinmann K, van der Linden V, van der Linden H, de Oliveira JRM, Arrais NMR, Melo A, Figueiredo T, Santos S, Meira JGC, Passos SD, de Almeida RP, Bispo AJB, Cavalheiro EA, Kalil J, Cunha-Neto E, Nakaya H, Andreata-Santos R, de Souza Ferreira LC, Verjovski-Almeida S, Ho PL, Passos-Bueno MR, Zatz M.

Nat Commun. 2018 Feb 2;9(1):475. doi: 10.1038/s41467-017-02790-9. Erratum in: Nat Commun. 2018 Mar 13;9(1):1114.

6.

Effects of proteasome inhibitor MG-132 on the parasite Schistosoma mansoni.

Morais ER, Oliveira KC, Paula RG, Ornelas AMM, Moreira ÉBC, Badoco FR, Magalhães LG, Verjovski-Almeida S, Rodrigues V.

PLoS One. 2017 Sep 12;12(9):e0184192. doi: 10.1371/journal.pone.0184192. eCollection 2017.

7.

The Schistosoma mansoni genome encodes thousands of long non-coding RNAs predicted to be functional at different parasite life-cycle stages.

Vasconcelos EJR, daSilva LF, Pires DS, Lavezzo GM, Pereira ASA, Amaral MS, Verjovski-Almeida S.

Sci Rep. 2017 Sep 5;7(1):10508. doi: 10.1038/s41598-017-10853-6.

8.

Repression of phosphatidylinositol transfer protein α ameliorates the pathology of Duchenne muscular dystrophy.

Vieira NM, Spinazzola JM, Alexander MS, Moreira YB, Kawahara G, Gibbs DE, Mead LC, Verjovski-Almeida S, Zatz M, Kunkel LM.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):6080-6085. doi: 10.1073/pnas.1703556114. Epub 2017 May 22.

9.

Histone deacetylase inhibition modulates histone acetylation at gene promoter regions and affects genome-wide gene transcription in Schistosoma mansoni.

Anderson L, Gomes MR, daSilva LF, Pereira ADSA, Mourão MM, Romier C, Pierce R, Verjovski-Almeida S.

PLoS Negl Trop Dis. 2017 Apr 13;11(4):e0005539. doi: 10.1371/journal.pntd.0005539. eCollection 2017 Apr.

10.

Corrigendum: HIPSTR and thousands of lncRNAs are heterogeneously expressed in human embryos, primordial germ cells and stable cell lines.

Yunusov D, Anderson L, DaSilva LF, Wysocka J, Ezashi T, Roberts RM, Verjovski-Almeida S.

Sci Rep. 2017 Mar 16;7:44632. doi: 10.1038/srep44632. No abstract available.

11.

Vulnerability of primitive human placental trophoblast to Zika virus.

Sheridan MA, Yunusov D, Balaraman V, Alexenko AP, Yabe S, Verjovski-Almeida S, Schust DJ, Franz AW, Sadovsky Y, Ezashi T, Roberts RM.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1587-E1596. doi: 10.1073/pnas.1616097114. Epub 2017 Feb 13.

12.

A Regulatory miRNA-mRNA Network Is Associated with Tissue Repair Induced by Mesenchymal Stromal Cells in Acute Kidney Injury.

de Almeida DC, Bassi ÊJ, Azevedo H, Anderson L, Origassa CS, Cenedeze MA, de Andrade-Oliveira V, Felizardo RJ, da Silva RC, Hiyane MI, Semedo P, Dos Reis MA, Moreira-Filho CA, Verjovski-Almeida S, Pacheco-Silva Á, Câmara NO.

Front Immunol. 2017 Jan 3;7:645. doi: 10.3389/fimmu.2016.00645. eCollection 2016.

13.

Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathway.

Roversi FM, Pericole FV, Machado-Neto JA, da Silva Santos Duarte A, Longhini AL, Corrocher FA, Palodetto B, Ferro KP, Rosa RG, Baratti MO, Verjovski-Almeida S, Traina F, Molinari A, Botta M, Saad ST.

Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):450-461. doi: 10.1016/j.bbadis.2016.11.013. Epub 2016 Nov 11.

14.

Retraction: Long non-coding RNA INXS is a critical mediator of BCL-XS induced apoptosis.

DeOcesano-Pereira C, Amaral MS, Parreira KS, Ayupe AC, Jacysyn JF, Amarante-Mendes GP, Reis EM, Verjovski-Almeida S.

Nucleic Acids Res. 2016 Nov 2;44(19):9518. Epub 2016 Aug 9. No abstract available.

15.

Interaction of an esophageal MEG protein from schistosomes with a human S100 protein involved in inflammatory response.

Orcia D, Zeraik AE, Lopes JLS, Macedo JNA, Santos CRD, Oliveira KC, Anderson L, Wallace BA, Verjovski-Almeida S, Araujo APU, DeMarco R.

Biochim Biophys Acta Gen Subj. 2017 Jan;1861(1 Pt A):3490-3497. doi: 10.1016/j.bbagen.2016.09.015. Epub 2016 Sep 15.

PMID:
27639541
16.

HIPSTR and thousands of lncRNAs are heterogeneously expressed in human embryos, primordial germ cells and stable cell lines.

Yunusov D, Anderson L, DaSilva LF, Wysocka J, Ezashi T, Roberts RM, Verjovski-Almeida S.

Sci Rep. 2016 Sep 8;6:32753. doi: 10.1038/srep32753. Erratum in: Sci Rep. 2017 Mar 16;7:44632.

17.

Identification of novel biomarkers associated with poor patient outcomes in invasive breast carcinoma.

Canevari RA, Marchi FA, Domingues MA, de Andrade VP, Caldeira JR, Verjovski-Almeida S, Rogatto SR, Reis EM.

Tumour Biol. 2016 Oct;37(10):13855-13870. Epub 2016 Aug 2.

PMID:
27485113
18.

Schistosoma mansoni Egg, Adult Male and Female Comparative Gene Expression Analysis and Identification of Novel Genes by RNA-Seq.

Anderson L, Amaral MS, Beckedorff F, Silva LF, Dazzani B, Oliveira KC, Almeida GT, Gomes MR, Pires DS, Setubal JC, DeMarco R, Verjovski-Almeida S.

PLoS Negl Trop Dis. 2015 Dec 31;9(12):e0004334. doi: 10.1371/journal.pntd.0004334. eCollection 2015 Dec.

19.

Jagged 1 Rescues the Duchenne Muscular Dystrophy Phenotype.

Vieira NM, Elvers I, Alexander MS, Moreira YB, Eran A, Gomes JP, Marshall JL, Karlsson EK, Verjovski-Almeida S, Lindblad-Toh K, Kunkel LM, Zatz M.

Cell. 2015 Nov 19;163(5):1204-1213. doi: 10.1016/j.cell.2015.10.049. Epub 2015 Nov 12.

20.

Human TNF-α induces differential protein phosphorylation in Schistosoma mansoni adult male worms.

Oliveira KC, Carvalho ML, Bonatto JM, Schechtman D, Verjovski-Almeida S.

Parasitol Res. 2016 Feb;115(2):817-28. doi: 10.1007/s00436-015-4812-5. Epub 2015 Nov 7.

PMID:
26547565
21.

Synergy of Omeprazole and Praziquantel In Vitro Treatment against Schistosoma mansoni Adult Worms.

Almeida GT, Lage RC, Anderson L, Venancio TM, Nakaya HI, Miyasato PA, Rofatto HK, Zerlotini A, Nakano E, Oliveira G, Verjovski-Almeida S.

PLoS Negl Trop Dis. 2015 Sep 24;9(9):e0004086. doi: 10.1371/journal.pntd.0004086. eCollection 2015.

22.

Global analysis of biogenesis, stability and sub-cellular localization of lncRNAs mapping to intragenic regions of the human genome.

Ayupe AC, Tahira AC, Camargo L, Beckedorff FC, Verjovski-Almeida S, Reis EM.

RNA Biol. 2015;12(8):877-92. doi: 10.1080/15476286.2015.1062960.

23.

Long non-coding RNA INXS is a critical mediator of BCL-XS induced apoptosis.

DeOcesano-Pereira C, Amaral MS, Parreira KS, Ayupe AC, Jacysyn JF, Amarante-Mendes GP, Reis EM, Verjovski-Almeida S.

Nucleic Acids Res. 2014 Jul;42(13):8343-55. doi: 10.1093/nar/gku561. Epub 2014 Jul 3. Retraction in: Nucleic Acids Res. 2016 Nov 2;44(19):9518.

24.

Imatinib treatment causes substantial transcriptional changes in adult Schistosoma mansoni in vitro exhibiting pleiotropic effects.

Buro C, Beckmann S, Oliveira KC, Dissous C, Cailliau K, Marhöfer RJ, Selzer PM, Verjovski-Almeida S, Grevelding CG.

PLoS Negl Trop Dis. 2014 Jun 12;8(6):e2923. doi: 10.1371/journal.pntd.0002923. eCollection 2014 Jun.

25.

Combinatory microarray and SuperSAGE analyses identify pairing-dependently transcribed genes in Schistosoma mansoni males, including follistatin.

Leutner S, Oliveira KC, Rotter B, Beckmann S, Buro C, Hahnel S, Kitajima JP, Verjovski-Almeida S, Winter P, Grevelding CG.

PLoS Negl Trop Dis. 2013 Nov 7;7(11):e2532. doi: 10.1371/journal.pntd.0002532. eCollection 2013 Nov.

26.

Expression analysis and in silico characterization of intronic long noncoding RNAs in renal cell carcinoma: emerging functional associations.

Fachel AA, Tahira AC, Vilella-Arias SA, Maracaja-Coutinho V, Gimba ER, Vignal GM, Campos FS, Reis EM, Verjovski-Almeida S.

Mol Cancer. 2013 Nov 15;12(1):140. doi: 10.1186/1476-4598-12-140.

27.

The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation.

Beckedorff FC, Ayupe AC, Crocci-Souza R, Amaral MS, Nakaya HI, Soltys DT, Menck CF, Reis EM, Verjovski-Almeida S.

PLoS Genet. 2013;9(8):e1003705. doi: 10.1371/journal.pgen.1003705. Epub 2013 Aug 22.

28.

Loss of caspase 7 expression is associated with poor prognosis in renal cell carcinoma clear cell subtype.

Vilella-Arias SA, Rocha RM, da Costa WH, Zequi Sde C, Guimarães GC, Verjovski-Almeida S, Soares FA, Reis EM.

Urology. 2013 Oct;82(4):974.e1-7. doi: 10.1016/j.urology.2013.06.026. Epub 2013 Aug 3.

PMID:
23920448
29.

Long non-coding RNAs and their implications in cancer epigenetics.

Beckedorff FC, Amaral MS, Deocesano-Pereira C, Verjovski-Almeida S.

Biosci Rep. 2013 Aug 30;33(4). pii: e00061. doi: 10.1042/BSR20130054. Review.

30.

Transcriptome analyses of inhibitor-treated schistosome females provide evidence for cooperating Src-kinase and TGFβ receptor pathways controlling mitosis and eggshell formation.

Buro C, Oliveira KC, Lu Z, Leutner S, Beckmann S, Dissous C, Cailliau K, Verjovski-Almeida S, Grevelding CG.

PLoS Pathog. 2013;9(6):e1003448. doi: 10.1371/journal.ppat.1003448. Epub 2013 Jun 13.

31.

Protein-coding genes and long noncoding RNAs are differentially expressed in dasatinib-treated chronic myeloid leukemia patients with resistance to imatinib.

Silveira RA, Fachel AA, Moreira YB, De Souza CA, Costa FF, Verjovski-Almeida S, Pagnano KB.

Hematology. 2014 Jan;19(1):31-41. doi: 10.1179/1607845413Y.0000000094. Epub 2013 Nov 25.

PMID:
23676950
32.

Immunization with tegument nucleotidases associated with a subcurative praziquantel treatment reduces worm burden following Schistosoma mansoni challenge.

Rofatto HK, Araujo-Montoya BO, Miyasato PA, Levano-Garcia J, Rodriguez D, Nakano E, Verjovski-Almeida S, Farias LP, Leite LC.

PeerJ. 2013 Apr 2;1:e58. doi: 10.7717/peerj.58. Print 2013.

33.

Metagenomic analysis of a tropical composting operation at the são paulo zoo park reveals diversity of biomass degradation functions and organisms.

Martins LF, Antunes LP, Pascon RC, de Oliveira JC, Digiampietri LA, Barbosa D, Peixoto BM, Vallim MA, Viana-Niero C, Ostroski EH, Telles GP, Dias Z, da Cruz JB, Juliano L, Verjovski-Almeida S, da Silva AM, Setubal JC.

PLoS One. 2013 Apr 24;8(4):e61928. doi: 10.1371/journal.pone.0061928. Print 2013. Erratum in: PLoS One. 2013;8(6). doi:10.1371/annotation/2cca811e-d45b-4854-a420-d0405309ef43.

34.

Effects of curcumin on the parasite Schistosoma mansoni: a transcriptomic approach.

Morais ER, Oliveira KC, Magalhães LG, Moreira EB, Verjovski-Almeida S, Rodrigues V.

Mol Biochem Parasitol. 2013 Feb;187(2):91-7. doi: 10.1016/j.molbiopara.2012.11.006. Epub 2012 Dec 29.

35.

ARHGAP21 is a RhoGAP for RhoA and RhoC with a role in proliferation and migration of prostate adenocarcinoma cells.

Lazarini M, Traina F, Machado-Neto JA, Barcellos KS, Moreira YB, Brandão MM, Verjovski-Almeida S, Ridley AJ, Saad ST.

Biochim Biophys Acta. 2013 Feb;1832(2):365-74. doi: 10.1016/j.bbadis.2012.11.010. Epub 2012 Nov 28.

36.

Schistosoma mansoni histones: from transcription to chromatin regulation; an in silico analysis.

Anderson L, Pierce RJ, Verjovski-Almeida S.

Mol Biochem Parasitol. 2012 Jun;183(2):105-14. doi: 10.1016/j.molbiopara.2012.03.001. Epub 2012 Mar 10. Review.

PMID:
22414701
37.

Perspectives of Long Non-Coding RNAs in Cancer Diagnostics.

Reis EM, Verjovski-Almeida S.

Front Genet. 2012 Mar 8;3:32. doi: 10.3389/fgene.2012.00032. eCollection 2012.

38.

Effect of human TGF-β on the gene expression profile of Schistosoma mansoni adult worms.

Oliveira KC, Carvalho ML, Verjovski-Almeida S, LoVerde PT.

Mol Biochem Parasitol. 2012 Jun;183(2):132-9. doi: 10.1016/j.molbiopara.2012.02.008. Epub 2012 Feb 25.

39.

Non-coding transcription characterization and annotation: a guide and web resource for non-coding RNA databases.

Paschoal AR, Maracaja-Coutinho V, Setubal JC, Simões ZL, Verjovski-Almeida S, Durham AM.

RNA Biol. 2012 Mar;9(3):274-82. doi: 10.4161/rna.19352. Epub 2012 Mar 1. Review.

PMID:
22336709
40.

Long noncoding intronic RNAs are differentially expressed in primary and metastatic pancreatic cancer.

Tahira AC, Kubrusly MS, Faria MF, Dazzani B, Fonseca RS, Maracaja-Coutinho V, Verjovski-Almeida S, Machado MC, Reis EM.

Mol Cancer. 2011 Nov 13;10:141. doi: 10.1186/1476-4598-10-141.

41.

Schistosoma mansoni: molecular characterization of Alkaline Phosphatase and expression patterns across life cycle stages.

Araujo-Montoya BO, Rofatto HK, Tararam CA, Farias LP, Oliveira KC, Verjovski-Almeida S, Wilson RA, Leite LC.

Exp Parasitol. 2011 Nov;129(3):284-91. doi: 10.1016/j.exppara.2011.07.008. Epub 2011 Jul 18.

42.

Curupira-1 and Curupira-2, two novel Mutator-like DNA transposons from the genomes of human parasites Schistosoma mansoni and Schistosoma japonicum.

Jacinto DS, Muniz Hdos S, Venancio TM, Wilson RA, Verjovski-Almeida S, Demarco R.

Parasitology. 2011 Aug;138(9):1124-33. doi: 10.1017/S0031182011000886. Epub 2011 Jul 15.

PMID:
21756422
43.

Exploring the Schistosoma mansoni adult male transcriptome using RNA-seq.

Almeida GT, Amaral MS, Beckedorff FC, Kitajima JP, DeMarco R, Verjovski-Almeida S.

Exp Parasitol. 2012 Sep;132(1):22-31. doi: 10.1016/j.exppara.2011.06.010. Epub 2011 Jul 2.

44.

Systems medicine and integrated care to combat chronic noncommunicable diseases.

Bousquet J, Anto JM, Sterk PJ, Adcock IM, Chung KF, Roca J, Agusti A, Brightling C, Cambon-Thomsen A, Cesario A, Abdelhak S, Antonarakis SE, Avignon A, Ballabio A, Baraldi E, Baranov A, Bieber T, Bockaert J, Brahmachari S, Brambilla C, Bringer J, Dauzat M, Ernberg I, Fabbri L, Froguel P, Galas D, Gojobori T, Hunter P, Jorgensen C, Kauffmann F, Kourilsky P, Kowalski ML, Lancet D, Pen CL, Mallet J, Mayosi B, Mercier J, Metspalu A, Nadeau JH, Ninot G, Noble D, Oztürk M, Palkonen S, Préfaut C, Rabe K, Renard E, Roberts RG, Samolinski B, Schünemann HJ, Simon HU, Soares MB, Superti-Furga G, Tegner J, Verjovski-Almeida S, Wellstead P, Wolkenhauer O, Wouters E, Balling R, Brookes AJ, Charron D, Pison C, Chen Z, Hood L, Auffray C.

Genome Med. 2011 Jul 6;3(7):43. doi: 10.1186/gm259.

45.

Non-coding RNAs in schistosomes: an unexplored world.

Oliveira KC, Carvalho ML, Maracaja-Coutinho V, Kitajima JP, Verjovski-Almeida S.

An Acad Bras Cienc. 2011 Jun;83(2):673-94. Review.

46.

E Schistosoma mansoni at the molecular and cellular biology of helminth parasites VI meeting.

Verjovski-Almeida S.

An Acad Bras Cienc. 2011 Jun;83(2):355-6. No abstract available.

47.

Gene structure and splicing in schistosomes.

Verjovski-Almeida S, DeMarco R.

J Proteomics. 2011 Aug 24;74(9):1515-8. doi: 10.1016/j.jprot.2011.03.022. Epub 2011 Apr 1. Review.

PMID:
21440689
48.

Screening the Schistosoma mansoni transcriptome for genes differentially expressed in the schistosomulum stage in search for vaccine candidates.

Farias LP, Tararam CA, Miyasato PA, Nishiyama MY Jr, Oliveira KC, Kawano T, Verjovski-Almeida S, Leite LC.

Parasitol Res. 2011 Jan;108(1):123-35. doi: 10.1007/s00436-010-2045-1. Epub 2010 Sep 18.

PMID:
20852890
49.

Identification of protein-coding and non-coding RNA expression profiles in CD34+ and in stromal cells in refractory anemia with ringed sideroblasts.

Baratti MO, Moreira YB, Traina F, Costa FF, Verjovski-Almeida S, Olalla-Saad ST.

BMC Med Genomics. 2010 Jul 15;3:30. doi: 10.1186/1755-8794-3-30.

50.

Protein variation in blood-dwelling schistosome worms generated by differential splicing of micro-exon gene transcripts.

DeMarco R, Mathieson W, Manuel SJ, Dillon GP, Curwen RS, Ashton PD, Ivens AC, Berriman M, Verjovski-Almeida S, Wilson RA.

Genome Res. 2010 Aug;20(8):1112-21. doi: 10.1101/gr.100099.109. Epub 2010 Jul 6.

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