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Development of a casemix classification to predict costs of home care in the Netherlands: a study protocol.

Elissen AMJ, Verhoeven GS, de Korte MH, van den Bulck AOE, Metzelthin SF, van der Weij LC, Stam J, Ruwaard D, Mikkers MC.

BMJ Open. 2020 Feb 17;10(2):e035683. doi: 10.1136/bmjopen-2019-035683.


Surfaces from the Visual Past: Recovering High-Resolution Terrain Data from Historic Aerial Imagery for Multitemporal Landscape Analysis.

Sevara C, Verhoeven G, Doneus M, Draganits E.

J Archaeol Method Theory. 2018;25(2):611-642. doi: 10.1007/s10816-017-9348-9. Epub 2017 Aug 21.


Intraobserver and interobserver agreement on the radiographical diagnosis of canine cranial cruciate ligament rupture.

Bogaerts E, Van der Vekens E, Verhoeven G, de Rooster H, Van Ryssen B, Samoy Y, Putcuyps I, Van Tilburg J, Devriendt N, Weekers F, Bertal M, Houdellier B, Scheemaeker S, Versteken J, Lamerand M, Feenstra L, Peelman L, Nieuwerburgh FV, Saunders JH, Broeckx BJG.

Vet Rec. 2018 Apr 28;182(17):484. doi: 10.1136/vr.104523. Epub 2018 Feb 9.



Coppieters E, Van Ryssen B, van Bree H, Verhoeven G, Broeckx B, de Bakker E, Deforce D, Gielen I.

Vet Radiol Ultrasound. 2016 Nov;57(6):572-581. doi: 10.1111/vru.12425. Epub 2016 Oct 4.


Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male.

Navarro G, Xu W, Jacobson DA, Wicksteed B, Allard C, Zhang G, De Gendt K, Kim SH, Wu H, Zhang H, Verhoeven G, Katzenellenbogen JA, Mauvais-Jarvis F.

Cell Metab. 2016 May 10;23(5):837-51. doi: 10.1016/j.cmet.2016.03.015. Epub 2016 Apr 28.


Arthroscopic, Computed Tomography, and Radiographic Findings in 25 Dogs With Lameness After Arthroscopic Treatment of Medial Coronoid Disease.

Coppieters E, Seghers H, Verhoeven G, Gielen I, Samoy Y, de Bakker E, Van Ryssen B.

Vet Surg. 2016 Feb;45(2):246-53. doi: 10.1111/vsu.12443. Epub 2016 Jan 15.


Toward the most ideal case-control design with related and unrelated dogs in whole-exome sequencing studies.

Broeckx BJ, Coopman F, Verhoeven GE, De Keulenaer S, De Meester E, Bavegems V, Smets P, Van Ryssen B, Van Nieuwerburgh F, Deforce D.

Anim Genet. 2016 Apr;47(2):200-7. doi: 10.1111/age.12400. Epub 2015 Dec 22.


An heuristic filtering tool to identify phenotype-associated genetic variants applied to human intellectual disability and canine coat colors.

Broeckx BJ, Coopman F, Verhoeven G, Bosmans T, Gielen I, Dingemanse W, Saunders JH, Deforce D, Van Nieuwerburgh F.

BMC Bioinformatics. 2015 Nov 19;16:391. doi: 10.1186/s12859-015-0822-7.


Improved canine exome designs, featuring ncRNAs and increased coverage of protein coding genes.

Broeckx BJ, Hitte C, Coopman F, Verhoeven GE, De Keulenaer S, De Meester E, Derrien T, Alfoldi J, Lindblad-Toh K, Bosmans T, Gielen I, Van Bree H, Van Ryssen B, Saunders JH, Van Nieuwerburgh F, Deforce D.

Sci Rep. 2015 Aug 3;5:12810. doi: 10.1038/srep12810.


Sertoli cell androgen receptor signalling in adulthood is essential for post-meiotic germ cell development.

Willems A, Roesl C, Mitchell RT, Milne L, Jeffery N, Smith S, Verhoeven G, Brown P, Smith LB.

Mol Reprod Dev. 2015 Sep;82(9):626-7. doi: 10.1002/mrd.22506. Epub 2015 Jun 9. No abstract available.


The androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female mice.

Fagman JB, Wilhelmson AS, Motta BM, Pirazzi C, Alexanderson C, De Gendt K, Verhoeven G, Holmäng A, Anesten F, Jansson JO, Levin M, Borén J, Ohlsson C, Krettek A, Romeo S, Tivesten Å.

FASEB J. 2015 Apr;29(4):1540-50. doi: 10.1096/fj.14-259234. Epub 2014 Dec 30.


Intra- and interobserver agreement on radiographic phenotype in the diagnosis of canine hip dysplasia.

Fortrie RR, Verhoeven G, Broeckx B, Duchateau L, Janssens L, Samoy Y, Schreurs E, Saunders J, van Bree H, Vandekerckhove P, Coopman F.

Vet Surg. 2015 May;44(4):467-73. doi: 10.1111/j.1532-950X.2014.12309.x. Epub 2014 Nov 20.


Erosion of the medial compartment of the canine elbow: occurrence, diagnosis and currently available treatment options.

Coppieters E, Gielen I, Verhoeven G, Van Vynckt D, Van Ryssen B.

Vet Comp Orthop Traumatol. 2015;28(1):9-18. doi: 10.3415/VCOT-13-12-0147. Epub 2014 Nov 14.


TTA Rapid: Description of the Technique and Short Term Clinical Trial Results of the First 50 Cases.

Samoy Y, Verhoeven G, Bosmans T, Van der Vekens E, de Bakker E, Verleyen P, Van Ryssen B.

Vet Surg. 2015 May;44(4):474-84. doi: 10.1111/j.1532-950X.2014.12298.x. Epub 2014 Oct 20.


The ligaments of the canine hip joint revisited.

Casteleyn C, den Ouden I, Coopman F, Verhoeven G, Van Cruchten S, Van Ginneken C, Van Ryssen B, Simoens P.

Anat Histol Embryol. 2015 Dec;44(6):433-40. doi: 10.1111/ahe.12155. Epub 2014 Oct 12.


Combined prevalence of inherited skeletal disorders in dog breeds in Belgium.

Coopman F, Broeckx B, Verelst E, Deforce D, Saunders J, Duchateau L, Verhoeven G.

Vet Comp Orthop Traumatol. 2014;27(5):395-7. doi: 10.3415/VCOT-13-11-0140. Epub 2014 Jul 31.


Development and performance of a targeted whole exome sequencing enrichment kit for the dog (Canis Familiaris Build 3.1).

Broeckx BJ, Coopman F, Verhoeven GE, Bavegems V, De Keulenaer S, De Meester E, Van Niewerburgh F, Deforce D.

Sci Rep. 2014 Jul 7;4:5597. doi: 10.1038/srep05597.


The effects of positioning, reason for screening and the referring veterinarian on prevalence estimates of canine hip dysplasia.

Broeckx BJ, Verhoeven G, Coopman F, Van Haeringen W, Bosmans T, Gielen I, Henckens S, Saunders JH, van Bree H, Van Ryssen B, Verbeke V, Van Steendam K, Van Nieuwerburgh F, Deforce D.

Vet J. 2014 Sep;201(3):378-84. doi: 10.1016/j.tvjl.2014.05.023. Epub 2014 May 22.


Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells.

Kilcoyne KR, Smith LB, Atanassova N, Macpherson S, McKinnell C, van den Driesche S, Jobling MS, Chambers TJ, De Gendt K, Verhoeven G, O'Hara L, Platts S, Renato de Franca L, Lara NL, Anderson RA, Sharpe RM.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1924-32. doi: 10.1073/pnas.1320735111. Epub 2014 Apr 21.


Genome-wide identification of AR-regulated genes translated in Sertoli cells in vivo using the RiboTag approach.

De Gendt K, Verhoeven G, Amieux PS, Wilkinson MF.

Mol Endocrinol. 2014 Apr;28(4):575-91. doi: 10.1210/me.2013-1391. Epub 2014 Feb 25.


Comparing Norberg angle, linear femoral overlap and surface femoral overlap in radiographic assessment of  the canine hip joint.

Janssens L, De Ridder M, Verhoeven G, Gielen I, van Bree H.

J Small Anim Pract. 2014 Mar;55(3):135-8. doi: 10.1111/jsap.12171. Epub 2013 Dec 24.


The prevalence of nine genetic disorders in a dog population from Belgium, the Netherlands and Germany.

Broeckx BJ, Coopman F, Verhoeven GE, Van Haeringen W, van de Goor L, Bosmans T, Gielen I, Saunders JH, Soetaert SS, Van Bree H, Van Neste C, Van Nieuwerburgh F, Van Ryssen B, Verelst E, Van Steendam K, Deforce D.

PLoS One. 2013 Sep 19;8(9):e74811. doi: 10.1371/journal.pone.0074811. eCollection 2013.


Anaesthetic arthrography of the shoulder joint in dogs.

Van Vynckt D, Verhoeven G, Samoy Y, Polis I, van Bree H, Van Ryssen B.

Vet Comp Orthop Traumatol. 2013;26(4):291-7. doi: 10.3415/VCOT-12-03-0041. Epub 2013 Apr 24.


Absence of long-range diffusion of OmpA in E. coli is not caused by its peptidoglycan binding domain.

Verhoeven GS, Dogterom M, den Blaauwen T.

BMC Microbiol. 2013 Mar 23;13:66. doi: 10.1186/1471-2180-13-66.


Worldwide screening for canine hip dysplasia: where are we now?

Verhoeven G, Fortrie R, Van Ryssen B, Coopman F.

Vet Surg. 2012 Jan;41(1):10-9. doi: 10.1111/j.1532-950X.2011.00929.x. Review.


A role for selective androgen response elements in the development of the epididymis and the androgen control of the 5α reductase II gene.

Kerkhofs S, Dubois V, De Gendt K, Helsen C, Clinckemalie L, Spans L, Schuit F, Boonen S, Vanderschueren D, Saunders PT, Verhoeven G, Claessens F.

FASEB J. 2012 Oct;26(10):4360-72. doi: 10.1096/fj.11-202283. Epub 2012 Jul 13.


Diagnostic intra-articular anaesthesia of the elbow in dogs with medial coronoid disease.

Van Vynckt D, Verhoeven G, Saunders J, Polis I, Samoy Y, Verschooten F, Van Ryssen B.

Vet Comp Orthop Traumatol. 2012;25(4):307-13. doi: 10.3415/VCOT-11-11-0166. Epub 2012 Jun 13.


The development of an inducible androgen receptor knockout model in mouse to study the postmeiotic effects of androgens on germ cell development.

Willems A, De Gendt K, Deboel L, Swinnen JV, Verhoeven G.

Spermatogenesis. 2011 Oct;1(4):341-353. Epub 2011 Oct 1.


Cryptorchidism in mice with an androgen receptor ablation in gubernaculum testis.

Kaftanovskaya EM, Huang Z, Barbara AM, De Gendt K, Verhoeven G, Gorlov IP, Agoulnik AI.

Mol Endocrinol. 2012 Apr;26(4):598-607. doi: 10.1210/me.2011-1283. Epub 2012 Feb 9.


Tissue- and cell-specific functions of the androgen receptor revealed through conditional knockout models in mice.

De Gendt K, Verhoeven G.

Mol Cell Endocrinol. 2012 Apr 16;352(1-2):13-25. doi: 10.1016/j.mce.2011.08.008. Epub 2011 Aug 18. Review.


Expression of Tubb3, a beta-tubulin isotype, is regulated by androgens in mouse and rat Sertoli cells.

De Gendt K, Denolet E, Willems A, Daniels VW, Clinckemalie L, Denayer S, Wilkinson MF, Claessens F, Swinnen JV, Verhoeven G.

Biol Reprod. 2011 Nov;85(5):934-45. doi: 10.1095/biolreprod.110.090704. Epub 2011 Jul 6.


Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal.

Memarzadeh S, Cai H, Janzen DM, Xin L, Lukacs R, Riedinger M, Zong Y, DeGendt K, Verhoeven G, Huang J, Witte ON.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7962-7. doi: 10.1073/pnas.1105243108. Epub 2011 Apr 25.


Selective ablation of the androgen receptor in mouse sertoli cells affects sertoli cell maturation, barrier formation and cytoskeletal development.

Willems A, Batlouni SR, Esnal A, Swinnen JV, Saunders PT, Sharpe RM, França LR, De Gendt K, Verhoeven G.

PLoS One. 2010 Nov 30;5(11):e14168. doi: 10.1371/journal.pone.0014168.


Targeted inactivation of the androgen receptor gene in murine proximal epididymis causes epithelial hypotrophy and obstructive azoospermia.

Krutskikh A, De Gendt K, Sharp V, Verhoeven G, Poutanen M, Huhtaniemi I.

Endocrinology. 2011 Feb;152(2):689-96. doi: 10.1210/en.2010-0768. Epub 2010 Nov 17.


The effect of a technical quality assessment of hip-extended radiographs on interobserver agreement in the diagnosis of canine hip dysplasia.

Verhoeven GE, Fortrie RR, Duchateau L, Saunders JH, Van Ryssen B, Van Bree H, Coopman F.

Vet Radiol Ultrasound. 2010 Sep-Oct;51(5):498-503.


Aberrant activation of fatty acid synthesis suppresses primary cilium formation and distorts tissue development.

Willemarck N, Rysman E, Brusselmans K, Van Imschoot G, Vanderhoydonc F, Moerloose K, Lerut E, Verhoeven G, van Roy F, Vleminckx K, Swinnen JV.

Cancer Res. 2010 Nov 15;70(22):9453-62. doi: 10.1158/0008-5472.CAN-10-2324. Epub 2010 Oct 1.


De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation.

Rysman E, Brusselmans K, Scheys K, Timmermans L, Derua R, Munck S, Van Veldhoven PP, Waltregny D, Daniëls VW, Machiels J, Vanderhoydonc F, Smans K, Waelkens E, Verhoeven G, Swinnen JV.

Cancer Res. 2010 Oct 15;70(20):8117-26. doi: 10.1158/0008-5472.CAN-09-3871. Epub 2010 Sep 28.


Androgen receptor-dependent and independent atheroprotection by testosterone in male mice.

Bourghardt J, Wilhelmson AS, Alexanderson C, De Gendt K, Verhoeven G, Krettek A, Ohlsson C, Tivesten A.

Endocrinology. 2010 Nov;151(11):5428-37. doi: 10.1210/en.2010-0663. Epub 2010 Sep 22.


Direct interactions of early and late assembling division proteins in Escherichia coli cells resolved by FRET.

Alexeeva S, Gadella TW Jr, Verheul J, Verhoeven GS, den Blaauwen T.

Mol Microbiol. 2010 Jul;77(2):384-98. doi: 10.1111/j.1365-2958.2010.07211.x. Epub 2010 May 19.


Androgens and spermatogenesis: lessons from transgenic mouse models.

Verhoeven G, Willems A, Denolet E, Swinnen JV, De Gendt K.

Philos Trans R Soc Lond B Biol Sci. 2010 May 27;365(1546):1537-56. doi: 10.1098/rstb.2009.0117. Review.


Direct action through the sertoli cells is essential for androgen stimulation of spermatogenesis.

O'Shaughnessy PJ, Verhoeven G, De Gendt K, Monteiro A, Abel MH.

Endocrinology. 2010 May;151(5):2343-8. doi: 10.1210/en.2009-1333. Epub 2010 Mar 12.


Androgen-induced Rhox homeobox genes modulate the expression of AR-regulated genes.

Hu Z, Dandekar D, O'Shaughnessy PJ, De Gendt K, Verhoeven G, Wilkinson MF.

Mol Endocrinol. 2010 Jan;24(1):60-75. doi: 10.1210/me.2009-0303. Epub 2009 Nov 9.


Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors.

O'Shaughnessy PJ, Monteiro A, Verhoeven G, De Gendt K, Abel MH.

Reproduction. 2010 Jan;139(1):177-84. doi: 10.1530/REP-09-0377.


Androgen receptor disruption increases the osteogenic response to mechanical loading in male mice.

Callewaert F, Bakker A, Schrooten J, Van Meerbeek B, Verhoeven G, Boonen S, Vanderschueren D.

J Bone Miner Res. 2010 Jan;25(1):124-31. doi: 10.1359/jbmr.091001.


Occurrence of testicular microlithiasis in androgen insensitive hypogonadal mice.

O'Shaughnessy PJ, Monteiro A, Verhoeven G, De Gendt K, Abel MH.

Reprod Biol Endocrinol. 2009 Aug 27;7:88. doi: 10.1186/1477-7827-7-88.


Differential bacterial surface display of peptides by the transmembrane domain of OmpA.

Verhoeven GS, Alexeeva S, Dogterom M, den Blaauwen T.

PLoS One. 2009 Aug 25;4(8):e6739. doi: 10.1371/journal.pone.0006739.


Organotypic cultures of prepubertal mouse testes: a method to study androgen action in sertoli cells while preserving their natural environment.

De Gendt K, McKinnell C, Willems A, Saunders PT, Sharpe RM, Atanassova N, Swinnen JV, Verhoeven G.

Biol Reprod. 2009 Dec;81(6):1083-92. doi: 10.1095/biolreprod.109.078360. Epub 2009 Jul 8.


Interobserver agreement on the assessability of standard ventrodorsal hip-extended radiographs and its effect on agreement in the diagnosis of canine hip dysplasia and on routine FCI scoring.

Verhoeven GE, Coopman F, Duchateau L, Bosmans T, Van Ryssen B, Van Bree H.

Vet Radiol Ultrasound. 2009 May-Jun;50(3):259-63.


Early effects of Sertoli cell-selective androgen receptor ablation on testicular gene expression.

Willems A, De Gendt K, Allemeersch J, Smith LB, Welsh M, Swinnen JV, Verhoeven G.

Int J Androl. 2010 Jun 1;33(3):507-17. doi: 10.1111/j.1365-2605.2009.00964.x. Epub 2009 Apr 12.


Conditional inactivation of androgen receptor gene in the nervous system: effects on male behavioral and neuroendocrine responses.

Raskin K, de Gendt K, Duittoz A, Liere P, Verhoeven G, Tronche F, Mhaouty-Kodja S.

J Neurosci. 2009 Apr 8;29(14):4461-70. doi: 10.1523/JNEUROSCI.0296-09.2009.

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