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A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals.

Deelen J, Kettunen J, Fischer K, van der Spek A, Trompet S, Kastenmüller G, Boyd A, Zierer J, van den Akker EB, Ala-Korpela M, Amin N, Demirkan A, Ghanbari M, van Heemst D, Ikram MA, van Klinken JB, Mooijaart SP, Peters A, Salomaa V, Sattar N, Spector TD, Tiemeier H, Verhoeven A, Waldenberger M, Würtz P, Davey Smith G, Metspalu A, Perola M, Menni C, Geleijnse JM, Drenos F, Beekman M, Jukema JW, van Duijn CM, Slagboom PE.

Nat Commun. 2019 Aug 20;10(1):3346. doi: 10.1038/s41467-019-11311-9.


Statin treatment increases lipoprotein(a) levels in subjects with low molecular weight apolipoprotein(a) phenotype.

Yahya R, Berk K, Verhoeven A, Bos S, van der Zee L, Touw J, Erhart G, Kronenberg F, Timman R, Sijbrands E, Roeters van Lennep J, Mulder M.

Atherosclerosis. 2019 Jul 3. pii: S0021-9150(19)31392-9. doi: 10.1016/j.atherosclerosis.2019.07.001. [Epub ahead of print]


Platelet storage properties are associated with donor age: in vitro quality of platelets from young donors and older donors with and without Type 2 diabetes.

Bontekoe IJ, van der Meer PF, Verhoeven AJ, de Korte D.

Vox Sang. 2019 Feb;114(2):129-136. doi: 10.1111/vox.12739. Epub 2018 Dec 10.


A field portable method for the semi-quantitative estimation of dehydration tolerance of photosynthetic tissues across distantly related land plants.

López-Pozo M, Flexas J, Gulías J, Carriquí M, Nadal M, Perera-Castro AV, Clemente-Moreno MJ, Gago J, Núñez-Olivera E, Martínez-Abaigar J, Hernández A, Artetxe U, Bentley J, Farrant JM, Verhoeven A, García-Plazaola JI, Fernández-Marín B.

Physiol Plant. 2018 Dec 4. doi: 10.1111/ppl.12890. [Epub ahead of print]


KIMBLE: A versatile visual NMR metabolomics workbench in KNIME.

Verhoeven A, Giera M, Mayboroda OA.

Anal Chim Acta. 2018 Dec 31;1044:66-76. doi: 10.1016/j.aca.2018.07.070. Epub 2018 Jul 30.


Lowering hospital walls to achieve health equity.

Matheson A, Bourke C, Verhoeven A, Khan MI, Nkunda D, Dahar Z, Ellison-Loschmann L.

BMJ. 2018 Sep 20;362:k3597. doi: 10.1136/bmj.k3597. No abstract available.


Use of monomeric and oligomeric flavanols in the dietary management of patients with type 2 diabetes mellitus and microalbuminuria (FLAVA trial): study protocol for a randomized controlled trial.

Rashid M, Verhoeven AJM, Mulder MT, Timman R, van Beek-Nieuwland Y, Athumani AA, Zandbergen AAM, van der Wiel HE, Sijbrands EJG, Berk KA.

Trials. 2018 Jul 16;19(1):379. doi: 10.1186/s13063-018-2762-9.


Shifting the balance between goals and habits: Five failures in experimental habit induction.

de Wit S, Kindt M, Knot SL, Verhoeven AAC, Robbins TW, Gasull-Camos J, Evans M, Mirza H, Gillan CM.

J Exp Psychol Gen. 2018 Jul;147(7):1043-1065. doi: 10.1037/xge0000402.


Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation.

Held NM, Kuipers EN, van Weeghel M, van Klinken JB, Denis SW, Lombès M, Wanders RJ, Vaz FM, Rensen PCN, Verhoeven AJ, Boon MR, Houtkooper RH.

Sci Rep. 2018 Jun 22;8(1):9562. doi: 10.1038/s41598-018-27875-3.


Metabolic liver inflammation in obesity does not robustly decrease hepatic and circulating CETP.

Blauw LL, Li Z, Rensen SS, Greve JWM, Verhoeven A, Derks RJ, Giera M, Wang Y, Rensen PCN.

Atherosclerosis. 2018 Aug;275:149-155. doi: 10.1016/j.atherosclerosis.2018.06.004. Epub 2018 Jun 7.


Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans.

Fleurbaaij F, Henneman AA, Corver J, Knetsch CW, Smits WK, Nauta ST, Giera M, Dragan I, Kumar N, Lawley TD, Verhoeven A, van Leeuwen HC, Kuijper EJ, Hensbergen PJ.

Sci Rep. 2018 May 25;8(1):8181. doi: 10.1038/s41598-018-26079-z.


Improved oxygenation dramatically alters metabolism and gene expression in cultured primary mouse hepatocytes.

Gilglioni EH, Chang JC, Duijst S, Go S, Adam AAA, Hoekstra R, Verhoeven AJ, Ishii-Iwamoto EL, Oude Elferink RPJ.

Hepatol Commun. 2018 Feb 9;2(3):299-312. doi: 10.1002/hep4.1140. eCollection 2018 Mar.


HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution.

Tol MJ, van der Lienden MJC, Gabriel TL, Hagen JJ, Scheij S, Veenendaal T, Klumperman J, Donker-Koopman WE, Verhoeven AJ, Overkleeft H, Aerts JM, Argmann CA, van Eijk M.

Autophagy. 2018;14(3):437-449. doi: 10.1080/15548627.2017.1419118. Epub 2018 Feb 17.


First evidence of freezing tolerance in a resurrection plant: insights into molecular mobility and zeaxanthin synthesis in the dark.

Fernández-Marín B, Neuner G, Kuprian E, Laza JM, García-Plazaola JI, Verhoeven A.

Physiol Plant. 2018 Aug;163(4):472-489. doi: 10.1111/ppl.12694. Epub 2018 Mar 25. No abstract available.


Iterative design of diffractive elements made of lossy materials.

Verhoeven AD, Wyrowski F, Turunen J.

J Opt Soc Am A Opt Image Sci Vis. 2018 Jan 1;35(1):45-54. doi: 10.1364/JOSAA.35.000045.


Group cognitive behavioural therapy and weight regain after diet in type 2 diabetes: results from the randomised controlled POWER trial.

Berk KA, Buijks HIM, Verhoeven AJM, Mulder MT, Özcan B, van 't Spijker A, Timman R, Busschbach JJ, Sijbrands EJ.

Diabetologia. 2018 Apr;61(4):790-799. doi: 10.1007/s00125-017-4531-9. Epub 2018 Jan 9.


Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies.

van der Lee SJ, Teunissen CE, Pool R, Shipley MJ, Teumer A, Chouraki V, Melo van Lent D, Tynkkynen J, Fischer K, Hernesniemi J, Haller T, Singh-Manoux A, Verhoeven A, Willemsen G, de Leeuw FA, Wagner H, van Dongen J, Hertel J, Budde K, Willems van Dijk K, Weinhold L, Ikram MA, Pietzner M, Perola M, Wagner M, Friedrich N, Slagboom PE, Scheltens P, Yang Q, Gertzen RE, Egert S, Li S, Hankemeier T, van Beijsterveldt CEM, Vasan RS, Maier W, Peeters CFW, Jörgen Grabe H, Ramirez A, Seshadri S, Metspalu A, Kivimäki M, Salomaa V, Demirkan A, Boomsma DI, van der Flier WM, Amin N, van Duijn CM.

Alzheimers Dement. 2018 Jun;14(6):707-722. doi: 10.1016/j.jalz.2017.11.012. Epub 2018 Jan 6. Erratum in: Alzheimers Dement. 2019 Feb;15(2):319.


Failing to pay heed to health warnings in a food-associated environment.

Verhoeven AAC, Watson P, de Wit S.

Appetite. 2018 Jan 1;120:616-626. doi: 10.1016/j.appet.2017.10.020. Epub 2017 Oct 18.


Role of the bicarbonate-responsive soluble adenylyl cyclase in cholangiocyte apoptosis in primary biliary cholangitis; a new hypothesis.

Chang JC, Go S, Verhoeven AJ, Beuers U, Oude Elferink RPJ.

Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1232-1239. doi: 10.1016/j.bbadis.2017.09.022. Epub 2017 Sep 28. Review.


Lipoprotein Lipase Maintains Microglial Innate Immunity in Obesity.

Gao Y, Vidal-Itriago A, Kalsbeek MJ, Layritz C, García-Cáceres C, Tom RZ, Eichmann TO, Vaz FM, Houtkooper RH, van der Wel N, Verhoeven AJ, Yan J, Kalsbeek A, Eckel RH, Hofmann SM, Yi CX.

Cell Rep. 2017 Sep 26;20(13):3034-3042. doi: 10.1016/j.celrep.2017.09.008.


A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose, and Type 2 Diabetes.

Liu J, van Klinken JB, Semiz S, van Dijk KW, Verhoeven A, Hankemeier T, Harms AC, Sijbrands E, Sheehan NA, van Duijn CM, Demirkan A.

Diabetes. 2017 Nov;66(11):2915-2926. doi: 10.2337/db17-0199. Epub 2017 Aug 28.


Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study.

Liu J, Semiz S, van der Lee SJ, van der Spek A, Verhoeven A, van Klinken JB, Sijbrands E, Harms AC, Hankemeier T, van Dijk KW, van Duijn CM, Demirkan A.

Metabolomics. 2017;13(9):104. doi: 10.1007/s11306-017-1239-2. Epub 2017 Jul 28.


Platelet storage performance is consistent by donor: a pilot study comparing "good" and "poor" storing platelets.

Bontekoe IJ, van der Meer PF, van den Hurk K, Verhoeven AJ, de Korte D.

Transfusion. 2017 Oct;57(10):2373-2380. doi: 10.1111/trf.14238. Epub 2017 Jul 13.


Soluble LR11 associates with aortic root calcification in asymptomatic treated male patients with familial hypercholesterolemia.

Vongpromek R, Bos S, Ten Kate GR, Bujo H, Jiang M, Nieman K, Schneider W, Roeters van Lennep JE, Verhoeven AJM, Sijbrands EJG, Mulder MT.

Atherosclerosis. 2017 Oct;265:299-304. doi: 10.1016/j.atherosclerosis.2017.06.018. Epub 2017 Jun 9.


Automated quantification of metabolites in blood-derived samples by NMR.

Verhoeven A, Slagboom E, Wuhrer M, Giera M, Mayboroda OA.

Anal Chim Acta. 2017 Jul 11;976:52-62. doi: 10.1016/j.aca.2017.04.013. Epub 2017 Apr 13.


A comparison of pine and spruce in recovery from winter stress; changes in recovery kinetics, and the abundance and phosphorylation status of photosynthetic proteins during winter.

Merry R, Jerrard J, Frebault J, Verhoeven A.

Tree Physiol. 2017 Sep 1;37(9):1239-1250. doi: 10.1093/treephys/tpx065.


An experimental investigation of breaking learnt habits with verbal implementation intentions.

Verhoeven AAC, Kindt M, Zomer CL, de Wit S.

Acta Psychol (Amst). 2018 Mar;184:124-136. doi: 10.1016/j.actpsy.2017.05.008. Epub 2017 May 26.


Diet-induced weight loss and markers of endothelial dysfunction and inflammation in treated patients with type 2 diabetes.

Berk KA, Oudshoorn TP, Verhoeven AJM, Mulder MT, Roks AJM, Dik WA, Timman R, Sijbrands EJG.

Clin Nutr ESPEN. 2016 Oct;15:101-106. doi: 10.1016/j.clnesp.2016.06.011. Epub 2016 Jul 25.


The emerging role of skeletal muscle extracellular matrix remodelling in obesity and exercise.

Martinez-Huenchullan S, McLennan SV, Verhoeven A, Twigg SM, Tam CS.

Obes Rev. 2017 Jul;18(7):776-790. doi: 10.1111/obr.12548. Epub 2017 May 5. Review.


The anti-inflammatory function of high-density lipoprotein in type II diabetes: A systematic review.

Lemmers RFH, van Hoek M, Lieverse AG, Verhoeven AJM, Sijbrands EJG, Mulder MT.

J Clin Lipidol. 2017 May - Jun;11(3):712-724.e5. doi: 10.1016/j.jacl.2017.03.013. Epub 2017 Mar 31. Review.


Novel protein biomarkers associated with coronary artery disease in statin-treated patients with familial hypercholesterolemia.

Bos S, Phillips M, Watts GF, Verhoeven AJM, Sijbrands EJG, Ward NC.

J Clin Lipidol. 2017 May - Jun;11(3):682-693. doi: 10.1016/j.jacl.2017.03.014. Epub 2017 Apr 4.


Effect of diet-induced weight loss on lipoprotein(a) levels in obese individuals with and without type 2 diabetes.

Berk KA, Yahya R, Verhoeven AJM, Touw J, Leijten FP, van Rossum EF, Wester VL, Lips MA, Pijl H, Timman R, Erhart G, Kronenberg F, Roeters van Lennep JE, Sijbrands EJG, Mulder MT.

Diabetologia. 2017 Jun;60(6):989-997. doi: 10.1007/s00125-017-4246-y. Epub 2017 Apr 6.


Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels.

den Hoedt S, Janssen CIF, Astarita G, Piomelli D, Leijten FPJ, Crivelli SM, Verhoeven AJM, de Vries HE, Walter J, Martinez-Martinez P, Sijbrands EJG, Kiliaan AJ, Mulder MT.

J Alzheimers Dis. 2017;60(3):769-781. doi: 10.3233/JAD-160739.


Carotid artery plaques and intima medial thickness in familial hypercholesteraemic patients on long-term statin therapy: A case control study.

Bos S, Duvekot MH, Ten Kate GR, Verhoeven AJ, Mulder MT, Schinkel AF, Nieman K, Watts GF, Sijbrands EJ, Roeters van Lennep JE.

Atherosclerosis. 2017 Jan;256:62-66. doi: 10.1016/j.atherosclerosis.2016.12.005. Epub 2016 Dec 2.


Upper bound of signal-relevant efficiency of constrained diffractive elements.

Verhoeven AD, Aagedal H, Wyrowski F, Turunen J.

J Opt Soc Am A Opt Image Sci Vis. 2016 Dec 1;33(12):2425-2430. doi: 10.1364/JOSAA.33.002425.


Metabolomic changes in CSF of migraine patients measured with 1H-NMR spectroscopy.

Zielman R, Postma R, Verhoeven A, Bakels F, van Oosterhout WP, Meissner A, van den Maagdenberg AM, Terwindt GM, Mayboroda OA, Ferrari MD.

Mol Biosyst. 2016 Nov 15;12(12):3674-3682.


Levels of the soluble LDL receptor-relative LR11 decrease in overweight individuals with type 2 diabetes upon diet-induced weight loss.

Berk KA, Vongpromek R, Jiang M, Schneider WJ, Timman R, Verhoeven AJ, Bujo H, Sijbrands EJ, Mulder MT.

Atherosclerosis. 2016 Nov;254:67-72. doi: 10.1016/j.atherosclerosis.2016.09.066. Epub 2016 Sep 22.


Predictors of Diet-Induced Weight Loss in Overweight Adults with Type 2 Diabetes.

Berk KA, Mulder MT, Verhoeven AJ, van Wietmarschen H, Boessen R, Pellis LP, van T Spijker A, Timman R, Ozcan B, Sijbrands EJ.

PLoS One. 2016 Aug 5;11(8):e0160774. doi: 10.1371/journal.pone.0160774. eCollection 2016.


A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity.

Tol MJ, Ottenhoff R, van Eijk M, Zelcer N, Aten J, Houten SM, Geerts D, van Roomen C, Bierlaagh MC, Scheij S, Hoeksema MA, Aerts JM, Bogan JS, Dorn GW 2nd, Argmann CA, Verhoeven AJ.

Diabetes. 2016 Sep;65(9):2591-605. doi: 10.2337/db16-0243. Epub 2016 Jun 20.


Analytical pitfalls and challenges in clinical metabolomics.

Kohler I, Verhoeven A, Derks RJ, Giera M.

Bioanalysis. 2016 Jul;8(14):1509-32. doi: 10.4155/bio-2016-0090. Epub 2016 Jun 21. Review.


Lomitapide affects HDL composition and function.

Yahya R, Favari E, Calabresi L, Verhoeven AJM, Zimetti F, Adorni MP, Gomaraschi M, Averna M, Cefalù AB, Bernini F, Sijbrands EJG, Mulder MT, Roeters van Lennep JE.

Atherosclerosis. 2016 Aug;251:15-18. doi: 10.1016/j.atherosclerosis.2016.05.005. Epub 2016 May 11.


HDL functionality in South Asians as compared to white Caucasians.

Bakker LE, Boon MR, Annema W, Dikkers A, van Eyk HJ, Verhoeven A, Mayboroda OA, Jukema JW, Havekes LM, Meinders AE, Willems van Dijk K, Jazet IM, Tietge UJ, Rensen PC.

Nutr Metab Cardiovasc Dis. 2016 Aug;26(8):697-705. doi: 10.1016/j.numecd.2016.02.010. Epub 2016 Feb 19.


Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

Kettunen J, Demirkan A, Würtz P, Draisma HH, Haller T, Rawal R, Vaarhorst A, Kangas AJ, Lyytikäinen LP, Pirinen M, Pool R, Sarin AP, Soininen P, Tukiainen T, Wang Q, Tiainen M, Tynkkynen T, Amin N, Zeller T, Beekman M, Deelen J, van Dijk KW, Esko T, Hottenga JJ, van Leeuwen EM, Lehtimäki T, Mihailov E, Rose RJ, de Craen AJ, Gieger C, Kähönen M, Perola M, Blankenberg S, Savolainen MJ, Verhoeven A, Viikari J, Willemsen G, Boomsma DI, van Duijn CM, Eriksson J, Jula A, Järvelin MR, Kaprio J, Metspalu A, Raitakari O, Salomaa V, Slagboom PE, Waldenberger M, Ripatti S, Ala-Korpela M.

Nat Commun. 2016 Mar 23;7:11122. doi: 10.1038/ncomms11122.


Implementation intention and planning interventions in Health Psychology: Recommendations from the Synergy Expert Group for research and practice.

Hagger MS, Luszczynska A, de Wit J, Benyamini Y, Burkert S, Chamberland PE, Chater A, Dombrowski SU, van Dongen A, French DP, Gauchet A, Hankonen N, Karekla M, Kinney AY, Kwasnicka D, Hing Lo S, López-Roig S, Meslot C, Marques MM, Neter E, Plass AM, Potthoff S, Rennie L, Scholz U, Stadler G, Stolte E, Ten Hoor G, Verhoeven A, Wagner M, Oettingen G, Sheeran P, Gollwitzer PM.

Psychol Health. 2016 Jul;31(7):814-39. doi: 10.1080/08870446.2016.1146719. Epub 2016 Mar 16.


Characterization of light-dependent regulation of state transitions in gymnosperms.

Verhoeven AS, Kertho A, Nguyen M.

Tree Physiol. 2016 Mar;36(3):325-34. doi: 10.1093/treephys/tpv140. Epub 2016 Jan 22.


[Universal healthcare in a mixed public-private system: the Australian experience].

Verhoeven A, Partel K, Thurecht L.

World Hosp Health Serv. 2016;52(4):28-30.


Discriminative Ability of Plasma Branched-Chain Amino Acid Levels for Glucose Intolerance in Families At Risk for Type 2 Diabetes.

Jainandunsing S, Wattimena JL, Verhoeven AJ, Langendonk JG, Rietveld T, Isaacs AJ, Sijbrands EJ, de Rooij FW.

Metab Syndr Relat Disord. 2016 Apr;14(3):175-81. doi: 10.1089/met.2015.0102. Epub 2015 Dec 14.


LR11/SorLA links triglyceride-rich lipoproteins to risk of developing cardiovascular disease in FH patients.

Vongpromek R, Bujo H, Hoekstra M, Schneider WJ, van der Zee L, Schinkel AF, Korporaal SJ, Dik WA, Ebinuma H, Jiang M, Verhoeven AJ, Sijbrands EJ, Mulder MT.

Atherosclerosis. 2015 Dec;243(2):429-37. doi: 10.1016/j.atherosclerosis.2015.10.009. Epub 2015 Oct 13.


Pharmacological Modulation of Photoreceptor Outer Segment Degradation in a Human iPS Cell Model of Inherited Macular Degeneration.

Singh R, Kuai D, Guziewicz KE, Meyer J, Wilson M, Lu J, Smith M, Clark E, Verhoeven A, Aguirre GD, Gamm DM.

Mol Ther. 2015 Nov;23(11):1700-1711. doi: 10.1038/mt.2015.141. Epub 2015 Aug 24.

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