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Items: 1 to 50 of 72

1.

Quantification of epicardial adipose tissue in patients undergoing hybrid ablation for atrial fibrillation.

Vroomen M, Olsthoorn JR, Maesen B, L'Espoir V, La Meir M, Das M, Maessen JG, Crijns HJGM, Verheule S, Pison L.

Eur J Cardiothorac Surg. 2019 Jul 1;56(1):79-86. doi: 10.1093/ejcts/ezy472.

PMID:
30753389
2.

Effect of Na+-channel blockade on the three-dimensional substrate of atrial fibrillation in a model of endo-epicardial dissociation and transmural conduction.

Gharaviri A, Verheule S, Eckstein J, Potse M, Krause R, Auricchio A, Kuijpers NHL, Schotten U.

Europace. 2018 Nov 1;20(suppl_3):iii69-iii76. doi: 10.1093/europace/euy236.

PMID:
30476060
3.

Rotors Detected by Phase Analysis of Filtered, Epicardial Atrial Fibrillation Electrograms Colocalize With Regions of Conduction Block.

Podziemski P, Zeemering S, Kuklik P, van Hunnik A, Maesen B, Maessen J, Crijns HJ, Verheule S, Schotten U.

Circ Arrhythm Electrophysiol. 2018 Oct;11(10):e005858. doi: 10.1161/CIRCEP.117.005858.

4.

Loss of Side-to-Side Connections Affects the Relative Contributions of the Sodium and Calcium Current to Transverse Propagation Between Strands of Atrial Myocytes.

Zhao J, Schotten U, Smaill B, Verheule S.

Front Physiol. 2018 Sep 4;9:1212. doi: 10.3389/fphys.2018.01212. eCollection 2018.

5.

Stationary Atrial Fibrillation Properties in the Goat Do Not Entail Stable or Recurrent Conduction Patterns.

van Hunnik A, Zeemering S, Podziemski P, Simons J, Gatta G, Hannink L, Maesen B, Kuiper M, Verheule S, Schotten U.

Front Physiol. 2018 Jul 27;9:947. doi: 10.3389/fphys.2018.00947. eCollection 2018.

6.

Arterial hypertension drives arrhythmia progression via specific structural remodeling in a porcine model of atrial fibrillation.

Manninger M, Zweiker D, van Hunnik A, Alogna A, Prassl AJ, Schipke J, Zeemering S, Zirngast B, Schönleitner P, Schwarzl M, Herbst V, Thon-Gutschi E, Huber S, Rohrer U, Ebner J, Brussee H, Pieske BM, Heinzel FR, Verheule S, Antoons G, Lueger A, Mühlfeld C, Plank G, Schotten U, Post H, Scherr D.

Heart Rhythm. 2018 Sep;15(9):1328-1336. doi: 10.1016/j.hrthm.2018.05.016. Epub 2018 May 23.

PMID:
29803020
7.

Cardioversion of persistent atrial fibrillation is associated with a 24-hour relapse gap: Observations from prolonged postcardioversion rhythm monitoring.

Weijs B, Limantoro I, Delhaas T, de Vos CB, Blaauw Y, Houben RPM, Verheule S, Pisters R, Crijns HJGM.

Clin Cardiol. 2018 Mar;41(3):366-371. doi: 10.1002/clc.22877. Epub 2018 Mar 22.

8.

The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models.

Ji Y, Varkevisser R, Opacic D, Bossu A, Kuiper M, Beekman JDM, Yang S, Khan AP, Dobrev D, Voigt N, Wang MZ, Verheule S, Vos MA, van der Heyden MAG.

Br J Pharmacol. 2017 Aug;174(15):2576-2590. doi: 10.1111/bph.13869. Epub 2017 Jun 28.

9.

Vernakalant does not alter early repolarization or contractility in normal and electrically remodelled atria.

van Hunnik A, Nasrallah H, Lau DH, Kuiper M, Verheule S, Schotten U.

Europace. 2018 Jan 1;20(1):140-148. doi: 10.1093/europace/eux025.

PMID:
28449044
10.

How disruption of endo-epicardial electrical connections enhances endo-epicardial conduction during atrial fibrillation.

Gharaviri A, Verheule S, Eckstein J, Potse M, Kuklik P, Kuijpers NH, Schotten U.

Europace. 2017 Feb 1;19(2):308-318. doi: 10.1093/europace/euv445.

PMID:
28175261
11.

Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase.

Reilly SN, Liu X, Carnicer R, Recalde A, Muszkiewicz A, Jayaram R, Carena MC, Wijesurendra R, Stefanini M, Surdo NC, Lomas O, Ratnatunga C, Sayeed R, Krasopoulos G, Rajakumar T, Bueno-Orovio A, Verheule S, Fulga TA, Rodriguez B, Schotten U, Casadei B.

Sci Transl Med. 2016 May 25;8(340):340ra74. doi: 10.1126/scitranslmed.aac4296.

12.

Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation.

Spronk HM, De Jong AM, Verheule S, De Boer HC, Maass AH, Lau DH, Rienstra M, van Hunnik A, Kuiper M, Lumeij S, Zeemering S, Linz D, Kamphuisen PW, Ten Cate H, Crijns HJ, Van Gelder IC, van Zonneveld AJ, Schotten U.

Eur Heart J. 2017 Jan 1;38(1):38-50. doi: 10.1093/eurheartj/ehw119. Epub 2016 Apr 12.

PMID:
27071821
13.

Cathepsin A mediates susceptibility to atrial tachyarrhythmia and impairment of atrial emptying function in Zucker diabetic fatty rats.

Linz D, Hohl M, Dhein S, Ruf S, Reil JC, Kabiri M, Wohlfart P, Verheule S, Böhm M, Sadowski T, Schotten U.

Cardiovasc Res. 2016 Jun 1;110(3):371-80. doi: 10.1093/cvr/cvw071. Epub 2016 Mar 31.

PMID:
27032673
14.

Mutual Regulation of Epicardial Adipose Tissue and Myocardial Redox State by PPAR-γ/Adiponectin Signalling.

Antonopoulos AS, Margaritis M, Verheule S, Recalde A, Sanna F, Herdman L, Psarros C, Nasrallah H, Coutinho P, Akoumianakis I, Brewer AC, Sayeed R, Krasopoulos G, Petrou M, Tarun A, Tousoulis D, Shah AM, Casadei B, Channon KM, Antoniades C.

Circ Res. 2016 Mar 4;118(5):842-55. doi: 10.1161/CIRCRESAHA.115.307856. Epub 2016 Jan 21.

15.

Atrial metabolism and tissue perfusion as determinants of electrical and structural remodelling in atrial fibrillation.

Opacic D, van Bragt KA, Nasrallah HM, Schotten U, Verheule S.

Cardiovasc Res. 2016 Apr 1;109(4):527-41. doi: 10.1093/cvr/cvw007. Epub 2016 Jan 19. Review.

PMID:
26786160
16.

Antiarrhythmic effect of vernakalant in electrically remodeled goat atria is caused by slowing of conduction and prolongation of postrepolarization refractoriness.

van Hunnik A, Lau DH, Zeemering S, Kuiper M, Verheule S, Schotten U.

Heart Rhythm. 2016 Apr;13(4):964-72. doi: 10.1016/j.hrthm.2015.12.009. Epub 2015 Dec 8.

PMID:
26681610
17.

The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results.

Schotten U, Hatem S, Ravens U, Jaïs P, Müller FU, Goette A, Rohr S, Antoons G, Pieske B, Scherr D, Oto A, Casadei B, Verheule S, Cartlidge D, Steinmeyer K, Götsche T, Dobrev D, Kockskämper J, Lendeckel U, Fabritz L, Kirchhof P, Camm AJ; EUTRAF investigators.

Europace. 2015 Oct;17(10):1457-66. doi: 10.1093/europace/euv252. Epub 2015 Sep 12. Review.

PMID:
26364316
18.

Evaluation of the role of miR-31-dependent reduction in dystrophin and nNOS on atrial-fibrillation-induced electrical remodelling in man.

Reilly S, Liu X, Carnicer R, Rajakumar T, Sayeed R, Krasopoulos G, Verheule S, Fulga T, Schotten U, Casadei B.

Lancet. 2015 Feb 26;385 Suppl 1:S82. doi: 10.1016/S0140-6736(15)60397-X.

PMID:
26312904
19.

Atrial fibrillation and rapid acute pacing regulate adipocyte/adipositas-related gene expression in the atria.

Chilukoti RK, Giese A, Malenke W, Homuth G, Bukowska A, Goette A, Felix SB, Kanaan J, Wollert HG, Evert K, Verheule S, Jais P, Hatem SN, Lendeckel U, Wolke C.

Int J Cardiol. 2015;187:604-13. doi: 10.1016/j.ijcard.2015.03.072. Epub 2015 Mar 23.

PMID:
25863735
20.

Indices of bipolar complex fractionated atrial electrograms correlate poorly with each other and atrial fibrillation substrate complexity.

Lau DH, Maesen B, Zeemering S, Kuklik P, van Hunnik A, Lankveld TA, Bidar E, Verheule S, Nijs J, Maessen J, Crijns H, Sanders P, Schotten U.

Heart Rhythm. 2015 Jul;12(7):1415-23. doi: 10.1016/j.hrthm.2015.03.017. Epub 2015 Mar 12.

PMID:
25771914
21.

Catheter-based renal denervation reduces atrial nerve sprouting and complexity of atrial fibrillation in goats.

Linz D, van Hunnik A, Hohl M, Mahfoud F, Wolf M, Neuberger HR, Casadei B, Reilly SN, Verheule S, Böhm M, Schotten U.

Circ Arrhythm Electrophysiol. 2015 Apr;8(2):466-74. doi: 10.1161/CIRCEP.114.002453. Epub 2015 Feb 23.

PMID:
25713217
22.

Dynamic regulation of atrial coronary blood flow in healthy adult pigs.

van Bragt KA, Nasrallah HM, Kuiper M, van Hunnik A, Kuijpers NH, Schotten U, Verheule S.

Heart Rhythm. 2015 May;12(5):991-1000. doi: 10.1016/j.hrthm.2015.01.016. Epub 2015 Jan 13.

PMID:
25595927
23.

Effects of renal denervation on atrial arrhythmogenesis.

Linz D, Hunnik Av, Ukena C, Mahfoud F, Ewen S, Verheule S, Böhm M, Schotten U.

Future Cardiol. 2014 Nov;10(6):813-22. doi: 10.2217/fca.14.43. Review.

PMID:
25495822
24.

Tachycardia-induced silencing of subcellular Ca2+ signaling in atrial myocytes.

Greiser M, Kerfant BG, Williams GS, Voigt N, Harks E, Dibb KM, Giese A, Meszaros J, Verheule S, Ravens U, Allessie MA, Gammie JS, van der Velden J, Lederer WJ, Dobrev D, Schotten U.

J Clin Invest. 2014 Nov;124(11):4759-72. doi: 10.1172/JCI70102. Epub 2014 Oct 20.

25.

Reconstruction of instantaneous phase of unipolar atrial contact electrogram using a concept of sinusoidal recomposition and Hilbert transform.

Kuklik P, Zeemering S, Maesen B, Maessen J, Crijns HJ, Verheule S, Ganesan AN, Schotten U.

IEEE Trans Biomed Eng. 2015 Jan;62(1):296-302. doi: 10.1109/TBME.2014.2350029. Epub 2014 Aug 20.

PMID:
25148659
26.

Role of endo-epicardial dissociation of electrical activity and transmural conduction in the development of persistent atrial fibrillation.

Verheule S, Eckstein J, Linz D, Maesen B, Bidar E, Gharaviri A, Schotten U.

Prog Biophys Mol Biol. 2014 Aug;115(2-3):173-85. doi: 10.1016/j.pbiomolbio.2014.07.007. Epub 2014 Jul 30. Review.

PMID:
25086270
27.

A prospective randomized controlled trial on the incidence and predictors of late-phase postoperative atrial fibrillation up to 30 days and the preventive value of biatrial pacing.

Bidar E, Maesen B, Nieman F, Verheule S, Schotten U, Maessen JG.

Heart Rhythm. 2014 Jul;11(7):1156-62. doi: 10.1016/j.hrthm.2014.03.040. Epub 2014 Mar 21.

PMID:
24657803
28.

Catheter Ablation Targeting Complex Fractionated Atrial Electrogram in Atrial Fibrillation.

Lau DH, Zeemering S, Maesen B, Kuklik P, Verheule S, Schotten U.

J Atr Fibrillation. 2013 Oct 31;6(3):907. doi: 10.4022/jafib.907. eCollection 2013 Oct-Nov. Review.

29.

Atrial supply-demand balance in healthy adult pigs: coronary blood flow, oxygen extraction, and lactate production during acute atrial fibrillation.

van Bragt KA, Nasrallah HM, Kuiper M, Luiken JJ, Schotten U, Verheule S.

Cardiovasc Res. 2014 Jan 1;101(1):9-19. doi: 10.1093/cvr/cvt239. Epub 2013 Oct 18.

PMID:
24142429
30.

Identification of recurring wavefront propagation patterns in atrial fibrillation using basis pursuit.

Zeemering S, Peeters R, van Hunnik A, Verheule S, Schotten U.

Conf Proc IEEE Eng Med Biol Soc. 2013;2013:2928-31. doi: 10.1109/EMBC.2013.6610153.

PMID:
24110340
31.

Rearrangement of atrial bundle architecture and consequent changes in anisotropy of conduction constitute the 3-dimensional substrate for atrial fibrillation.

Maesen B, Zeemering S, Afonso C, Eckstein J, Burton RA, van Hunnik A, Stuckey DJ, Tyler D, Maessen J, Grau V, Verheule S, Kohl P, Schotten U.

Circ Arrhythm Electrophysiol. 2013 Oct;6(5):967-75. doi: 10.1161/CIRCEP.113.000050. Epub 2013 Aug 22.

PMID:
23969531
32.

Connexin diversity in the heart: insights from transgenic mouse models.

Verheule S, Kaese S.

Front Pharmacol. 2013 Jun 27;4:81. doi: 10.3389/fphar.2013.00081. Print 2013.

33.

The ECG in cardiovascular-relevant animal models of electrophysiology.

Kaese S, Frommeyer G, Verheule S, van Loon G, Gehrmann J, Breithardt G, Eckardt L.

Herzschrittmacherther Elektrophysiol. 2013 Jun;24(2):84-91. doi: 10.1007/s00399-013-0260-z. Epub 2013 Jun 6.

PMID:
23740318
34.

Transmural conduction is the predominant mechanism of breakthrough during atrial fibrillation: evidence from simultaneous endo-epicardial high-density activation mapping.

Eckstein J, Zeemering S, Linz D, Maesen B, Verheule S, van Hunnik A, Crijns H, Allessie MA, Schotten U.

Circ Arrhythm Electrophysiol. 2013 Apr;6(2):334-41. doi: 10.1161/CIRCEP.113.000342. Epub 2013 Mar 19.

PMID:
23512204
35.

Loss of continuity in the thin epicardial layer because of endomysial fibrosis increases the complexity of atrial fibrillatory conduction.

Verheule S, Tuyls E, Gharaviri A, Hulsmans S, van Hunnik A, Kuiper M, Serroyen J, Zeemering S, Kuijpers NH, Schotten U.

Circ Arrhythm Electrophysiol. 2013 Feb;6(1):202-11. doi: 10.1161/CIRCEP.112.975144. Epub 2013 Feb 6.

PMID:
23390124
36.

Automated quantification of atrial fibrillation complexity by probabilistic electrogram analysis and fibrillation wave reconstruction.

Zeemering S, Maesen B, Nijs J, Lau DH, Granier M, Verheule S, Schotten U.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:6357-60. doi: 10.1109/EMBC.2012.6347448.

PMID:
23367383
37.

A computer model of endo-epicardial electrical dissociation and transmural conduction during atrial fibrillation.

Gharaviri A, Verheule S, Eckstein J, Potse M, Kuijpers NH, Schotten U.

Europace. 2012 Nov;14 Suppl 5:v10-v16. doi: 10.1093/europace/eus270.

PMID:
23104905
38.

Cardiac electrophysiology in mice: a matter of size.

Kaese S, Verheule S.

Front Physiol. 2012 Sep 5;3:345. doi: 10.3389/fphys.2012.00345. eCollection 2012.

39.

Stability of complex fractionated atrial electrograms: a systematic review.

Lau DH, Maesen B, Zeemering S, Verheule S, Crijns HJ, Schotten U.

J Cardiovasc Electrophysiol. 2012 Sep;23(9):980-7. doi: 10.1111/j.1540-8167.2012.02335.x. Epub 2012 May 3. Review.

PMID:
22554025
40.

Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice.

Kirchhof P, Marijon E, Fabritz L, Li N, Wang W, Wang T, Schulte K, Hanstein J, Schulte JS, Vogel M, Mougenot N, Laakmann S, Fortmueller L, Eckstein J, Verheule S, Kaese S, Staab A, Grote-Wessels S, Schotten U, Moubarak G, Wehrens XH, Schmitz W, Hatem S, Müller FU.

Int J Cardiol. 2013 Jun 20;166(2):366-74. doi: 10.1016/j.ijcard.2011.10.057. Epub 2011 Nov 16. Erratum in: Int J Cardiol. 2014 Apr 1;172(3):631.

PMID:
22093963
41.

Stimulation of the intra-cardiac vagal nerves innervating the AV-node to control ventricular rate during AF: specificity, parameter optimization and chronic use up to 3 months.

Kornet L, van Hunnik A, Michels K, Verheule S, Della Scala A, West T, Kessels R, Cornelussen R.

J Interv Card Electrophysiol. 2012 Jan;33(1):7-18. doi: 10.1007/s10840-011-9619-4. Epub 2011 Oct 4.

PMID:
21969125
42.

Atrial sources of reactive oxygen species vary with the duration and substrate of atrial fibrillation: implications for the antiarrhythmic effect of statins.

Reilly SN, Jayaram R, Nahar K, Antoniades C, Verheule S, Channon KM, Alp NJ, Schotten U, Casadei B.

Circulation. 2011 Sep 6;124(10):1107-17. doi: 10.1161/CIRCULATIONAHA.111.029223. Epub 2011 Aug 15.

PMID:
21844076
43.

Leaky ryanodine receptors in the failing heart: the root of all evil?

Kerfant BG, Verheule S, Schotten U.

Cardiovasc Res. 2011 Jun 1;90(3):399-401. doi: 10.1093/cvr/cvr086. Epub 2011 Mar 29. No abstract available.

PMID:
21447705
44.

PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression.

Kirchhof P, Kahr PC, Kaese S, Piccini I, Vokshi I, Scheld HH, Rotering H, Fortmueller L, Laakmann S, Verheule S, Schotten U, Fabritz L, Brown NA.

Circ Cardiovasc Genet. 2011 Apr;4(2):123-33. doi: 10.1161/CIRCGENETICS.110.958058. Epub 2011 Jan 31.

PMID:
21282332
45.

Pathophysiological mechanisms of atrial fibrillation: a translational appraisal.

Schotten U, Verheule S, Kirchhof P, Goette A.

Physiol Rev. 2011 Jan;91(1):265-325. doi: 10.1152/physrev.00031.2009. Review. Erratum in: Physiol Rev. 2011 Oct;91(4):1533.

46.

Mechanoelectrical coupling enhances initiation and affects perpetuation of atrial fibrillation during acute atrial dilation.

Kuijpers NH, Potse M, van Dam PM, ten Eikelder HM, Verheule S, Prinzen FW, Schotten U.

Heart Rhythm. 2011 Mar;8(3):429-36. doi: 10.1016/j.hrthm.2010.11.020. Epub 2010 Nov 12.

PMID:
21075218
47.

Time course and mechanisms of endo-epicardial electrical dissociation during atrial fibrillation in the goat.

Eckstein J, Maesen B, Linz D, Zeemering S, van Hunnik A, Verheule S, Allessie M, Schotten U.

Cardiovasc Res. 2011 Mar 1;89(4):816-24. doi: 10.1093/cvr/cvq336. Epub 2010 Oct 26.

PMID:
20978006
48.

Fibrillatory conduction in the atrial free walls of goats in persistent and permanent atrial fibrillation.

Verheule S, Tuyls E, van Hunnik A, Kuiper M, Schotten U, Allessie M.

Circ Arrhythm Electrophysiol. 2010 Dec;3(6):590-9. doi: 10.1161/CIRCEP.109.931634. Epub 2010 Oct 11.

PMID:
20937721
49.

Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability.

Blana A, Kaese S, Fortmüller L, Laakmann S, Damke D, van Bragt K, Eckstein J, Piccini I, Kirchhefer U, Nattel S, Breithardt G, Carmeliet P, Carmeliet E, Schotten U, Verheule S, Kirchhof P, Fabritz L.

Heart Rhythm. 2010 Dec;7(12):1862-9. doi: 10.1016/j.hrthm.2010.08.016. Epub 2010 Aug 19.

PMID:
20728579
50.

Enhanced late na(+) currents in atrial fibrillation new drug target or just an epiphenomenon?

Schotten U, Verheule S, Kerfant BG, Greiser M.

J Am Coll Cardiol. 2010 May 25;55(21):2343-5. doi: 10.1016/j.jacc.2010.01.046. No abstract available.

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