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Items: 45

1.

Performance assessment of the Illumina massively parallel sequencing platform for deep sequencing analysis of viral minority variants.

Thys K, Verhasselt P, Reumers J, Verbist BM, Maes B, Aerssens J.

J Virol Methods. 2015 Sep 1;221:29-38. doi: 10.1016/j.jviromet.2015.04.022. Epub 2015 Apr 25.

PMID:
25917877
2.

Assessment of the microbiota in microdissected tissues of Crohn's disease patients.

De Hertogh G, Lemmens B, Verhasselt P, de Hoogt R, Sagaert X, Joossens M, Van Assche G, Rutgeerts P, Vermeire S, Aerssens J.

Int J Inflam. 2012;2012:505674. doi: 10.1155/2012/505674. Epub 2011 Dec 7.

3.

Minor variant detection in amplicons using 454 massive parallel pyrosequencing: experiences and considerations for successful applications.

Vandenbroucke I, Van Marck H, Verhasselt P, Thys K, Mostmans W, Dumont S, Van Eygen V, Coen K, Tuefferd M, Aerssens J.

Biotechniques. 2011 Sep;51(3):167-77. doi: 10.2144/000113733.

4.

HIV-1 nucleotide mixture detection in the virco(®)TYPE HIV-1 genotyping assay: a comparison between Sanger sequencing and 454 pyrosequencing.

De Wolf H, Van Marck H, Mostmans W, Thys K, Vandenbroucke I, Van Eygen V, Pattery T, Verhasselt P, Aerssens J.

J Virol Methods. 2011 Jul;175(1):129-32. doi: 10.1016/j.jviromet.2011.04.023. Epub 2011 Apr 27.

PMID:
21549149
5.

Rates and mechanisms of resistance development in Mycobacterium tuberculosis to a novel diarylquinoline ATP synthase inhibitor.

Huitric E, Verhasselt P, Koul A, Andries K, Hoffner S, Andersson DI.

Antimicrob Agents Chemother. 2010 Mar;54(3):1022-8. doi: 10.1128/AAC.01611-09. Epub 2009 Dec 28.

6.

Alternative splicing and exon duplication generates 10 unique porcine 5-HT 4 receptor splice variants including a functional homofusion variant.

De Maeyer JH, Aerssens J, Verhasselt P, Lefebvre RA.

Physiol Genomics. 2008 Jun 12;34(1):22-33. doi: 10.1152/physiolgenomics.00038.2008. Epub 2008 Apr 22.

PMID:
18430808
7.

In vitro antimycobacterial spectrum of a diarylquinoline ATP synthase inhibitor.

Huitric E, Verhasselt P, Andries K, Hoffner SE.

Antimicrob Agents Chemother. 2007 Nov;51(11):4202-4. Epub 2007 Aug 20.

8.

Validation of 16S rDNA sequencing in microdissected bowel biopsies from Crohn's disease patients to assess bacterial flora diversity.

De Hertogh G, Aerssens J, de Hoogt R, Peeters P, Verhasselt P, Van Eyken P, Ectors N, Vermeire S, Rutgeerts P, Coulie B, Geboes K.

J Pathol. 2006 Aug;209(4):532-9.

PMID:
16739113
9.

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis.

Andries K, Verhasselt P, Guillemont J, Göhlmann HW, Neefs JM, Winkler H, Van Gestel J, Timmerman P, Zhu M, Lee E, Williams P, de Chaffoy D, Huitric E, Hoffner S, Cambau E, Truffot-Pernot C, Lounis N, Jarlier V.

Science. 2005 Jan 14;307(5707):223-7. Epub 2004 Dec 9.

10.

Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.

Peeters PJ, Baker A, Goris I, Daneels G, Verhasselt P, Luyten WH, Geysen JJ, Kass SU, Moechars DW.

Brain Res Dev Brain Res. 2004 Jun 21;150(2):89-101.

PMID:
15158073
11.

A physical map of the chromosome 12 centromere.

Vermeesch JR, Duhamel H, Raeymaekers P, Van Zand K, Verhasselt P, Fryns JP, Marynen P.

Cytogenet Genome Res. 2003;103(1-2):63-73.

PMID:
15004466
12.

Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients.

Paulussen AD, Gilissen RA, Armstrong M, Doevendans PA, Verhasselt P, Smeets HJ, Schulze-Bahr E, Haverkamp W, Breithardt G, Cohen N, Aerssens J.

J Mol Med (Berl). 2004 Mar;82(3):182-8. Epub 2004 Feb 4.

PMID:
14760488
13.

Mutation analysis in congenital Long QT Syndrome--a case with missense mutations in KCNQ1 and SCN5A.

Paulussen A, Matthijs G, Gewillig M, Verhasselt P, Cohen N, Aerssens J.

Genet Test. 2003 Spring;7(1):57-61.

PMID:
12820704
14.

Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule.

Bender E, Buist A, Jurzak M, Langlois X, Baggerman G, Verhasselt P, Ercken M, Guo HQ, Wintmolders C, Van den Wyngaert I, Van Oers I, Schoofs L, Luyten W.

Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8573-8.

15.

Characterization of platelet-derived growth factor-C (PDGF-C): expression in normal and tumor cells, biological activity and chromosomal localization.

Dijkmans J, Xu J, Masure S, Dhanaraj S, Gosiewska A, Geesin J, Sprengel J, Harris S, Verhasselt P, Gordon R, Yon J.

Int J Biochem Cell Biol. 2002 Apr;34(4):414-26.

PMID:
11854040
16.

An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans.

De Backer MD, Nelissen B, Logghe M, Viaene J, Loonen I, Vandoninck S, de Hoogt R, Dewaele S, Simons FA, Verhasselt P, Vanhoof G, Contreras R, Luyten WH.

Nat Biotechnol. 2001 Mar;19(3):235-41. Erratum in: Nat Biotechnol 2001 Jul;19(7):681.

PMID:
11231556
17.

Mammalian GFRalpha -4, a divergent member of the GFRalpha family of coreceptors for glial cell line-derived neurotrophic factor family ligands, is a receptor for the neurotrophic factor persephin.

Masure S, Cik M, Hoefnagel E, Nosrat CA, Van der Linden I, Scott R, Van Gompel P, Lesage AS, Verhasselt P, Ibáñez CF, Gordon RD.

J Biol Chem. 2000 Dec 15;275(50):39427-34.

18.

Cloning and characterization of human histone deacetylase 8.

Van den Wyngaert I, de Vries W, Kremer A, Neefs J, Verhasselt P, Luyten WH, Kass SU.

FEBS Lett. 2000 Jul 28;478(1-2):77-83.

19.

Two linked mutations in transcriptional regulatory elements of the CYP3A5 gene constitute the major genetic determinant of polymorphic activity in humans.

Paulussen A, Lavrijsen K, Bohets H, Hendrickx J, Verhasselt P, Luyten W, Konings F, Armstrong M.

Pharmacogenetics. 2000 Jul;10(5):415-24.

PMID:
10898111
20.

Analysis of the human KCNH2(HERG) gene: identification and characterization of a novel mutation Y667X associated with long QT syndrome and a non-pathological 9 bp insertion.

Paulussen A, Yang P, Pangalos M, Verhasselt P, Marrannes R, Verfaille C, Vandenberk I, Crabbe R, Konings F, Luyten W, Armstrong M.

Hum Mutat. 2000 May;15(5):483.

PMID:
10790218
21.

Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variant.

Bender E, Pindon A, van Oers I, Zhang YB, Gommeren W, Verhasselt P, Jurzak M, Leysen J, Luyten W.

J Neurochem. 2000 Feb;74(2):478-89.

22.

Enovin, a member of the glial cell-line-derived neurotrophic factor (GDNF) family with growth promoting activity on neuronal cells. Existence and tissue-specific expression of different splice variants.

Masure S, Geerts H, Cik M, Hoefnagel E, Van Den Kieboom G, Tuytelaars A, Harris S, Lesage AS, Leysen JE, Van Der Helm L, Verhasselt P, Yon J, Gordon RD.

Eur J Biochem. 1999 Dec;266(3):892-902.

23.

Accumulation of 3-ketosteroids induced by itraconazole in azole-resistant clinical Candida albicans isolates.

Marichal P, Gorrens J, Laurijssens L, Vermuyten K, Van Hove C, Le Jeune L, Verhasselt P, Sanglard D, Borgers M, Ramaekers FC, Odds F, Vanden Bossche H.

Antimicrob Agents Chemother. 1999 Nov;43(11):2663-70.

24.

Contribution of mutations in the cytochrome P450 14alpha-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans.

Marichal P, Koymans L, Willemsens S, Bellens D, Verhasselt P, Luyten W, Borgers M, Ramaekers FCS, Odds FC, Vanden Bossche H.

Microbiology. 1999 Oct;145 ( Pt 10):2701-2713. doi: 10.1099/00221287-145-10-2701.

PMID:
10537192
25.

Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3.

Masure S, Haefner B, Wesselink JJ, Hoefnagel E, Mortier E, Verhasselt P, Tuytelaars A, Gordon R, Richardson A.

Eur J Biochem. 1999 Oct 1;265(1):353-60.

26.

Isolation and expression of novel human glutamate carboxypeptidases with N-acetylated alpha-linked acidic dipeptidase and dipeptidyl peptidase IV activity.

Pangalos MN, Neefs JM, Somers M, Verhasselt P, Bekkers M, van der Helm L, Fraiponts E, Ashton D, Gordon RD.

J Biol Chem. 1999 Mar 26;274(13):8470-83.

27.

Structure of the human histamine H1 receptor gene.

De Backer MD, Loonen I, Verhasselt P, Neefs JM, Luyten WH.

Biochem J. 1998 Nov 1;335 ( Pt 3):663-70.

28.

Identification of a human homologue of the Schizosaccharomyces pombe rad17+ checkpoint gene.

Parker AE, Van de Weyer I, Laus MC, Verhasselt P, Luyten WH.

J Biol Chem. 1998 Jul 17;273(29):18340-6. Erratum in: J Biol Chem 1999 Aug 20;274(34):24438.

29.

A human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonuclease.

Parker AE, Van de Weyer I, Laus MC, Oostveen I, Yon J, Verhasselt P, Luyten WH.

J Biol Chem. 1998 Jul 17;273(29):18332-9.

30.

Molecular cloning, expression and tissue distribution of glial-cell-line-derived neurotrophic factor family receptor alpha-3 (GFRalpha-3).

Masure S, Cik M, Pangalos MN, Bonaventure P, Verhasselt P, Lesage AS, Leysen JE, Gordon RD.

Eur J Biochem. 1998 Feb 1;251(3):622-30.

31.

Cloning and expression of a human serotonin 5-HT4 receptor cDNA.

Van den Wyngaert I, Gommeren W, Verhasselt P, Jurzak M, Leysen J, Luyten W, Bender E.

J Neurochem. 1997 Nov;69(5):1810-9.

32.

The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.

Philippsen P, Kleine K, Pöhlmann R, Düsterhöft A, Hamberg K, Hegemann JH, Obermaier B, Urrestarazu LA, Aert R, Albermann K, Altmann R, André B, Baladron V, Ballesta JP, Bécam AM, Beinhauer J, Boskovic J, Buitrago MJ, Bussereau F, Coster F, Crouzet M, D'Angelo M, Dal Pero F, De Antoni A, Del Rey F, Doignon F, Domdey H, Dubois E, Fiedler T, Fleig U, Floeth M, Fritz C, Gaillardin C, Garcia-Cantalejo JM, Glansdorff NN, Goffeau A, Gueldener U, Herbert C, Heumann K, Heuss-Neitzel D, Hilbert H, Hinni K, Iraqui Houssaini I, Jacquet M, Jimenez A, Jonniaux JL, Karpfinger L, Lanfranchi G, Lepingle A, Levesque H, Lyck R, Maftahi M, Mallet L, Maurer KC, Messenguy F, Mewes HW, Mösti D, Nasr F, Nicaud JM, Niedenthal RK, Pandolfo D, Piérard A, Piravandi E, Planta RJ, Pohl TM, Purnelle B, Rebischung C, Remacha M, Revuelta JL, Rinke M, Saiz JE, Sartorello F, Scherens B, Sen-Gupta M, Soler-Mira A, Urbanus JH, Valle G, Van Dyck L, Verhasselt P, Vierendeels F, Vissers S, Voet M, Volckaert G, Wach A, Wambutt R, Wedler H, Zollner A, Hani J.

Nature. 1997 May 29;387(6632 Suppl):93-8.

PMID:
9169873
35.

Identification of a gene encoding a homocitrate synthase isoenzyme of Saccharomyces cerevisiae.

Ramos F, Verhasselt P, Feller A, Peeters P, Wach A, Dubois E, Volckaert G.

Yeast. 1996 Oct;12(13):1315-20.

38.

Insertional re-activation of a chloramphenicol acetyltransferase misfolding mutant protein.

Robben J, Van der Schueren J, Verhasselt P, Aert R, Volckaert G.

Protein Eng. 1995 Feb;8(2):159-65.

PMID:
7630887
39.
40.

Assessment of colinearity between large cloned DNA fragments and genomic DNA.

Verhasselt P, Volckaert G.

PCR Methods Appl. 1994 Oct;4(2):129-32. No abstract available.

41.
42.

Open reading frame analysis by selective PCR-mediated deletion mutagenesis.

Verhasselt P, Reekmans MJ, Volckaert G.

Genet Anal Tech Appl. 1993 Feb;10(1):16-23.

PMID:
8329219
44.
45.

Cloning and expression of a Clostridium acetobutylicum alpha-amylase gene in Escherichia coli.

Verhasselt P, Poncelet F, Vits K, Van Gool A, Vanderleyden J.

FEMS Microbiol Lett. 1989 May;50(1-2):135-40.

PMID:
2661316

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