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EU postmarket surveillance plans for medical devices.

Pane J, Francisca RDC, Verhamme KMC, Orozco M, Viroux H, Rebollo I, Sturkenboom MCJM.

Pharmacoepidemiol Drug Saf. 2019 Jul 18. doi: 10.1002/pds.4859. [Epub ahead of print] Review.


FCER2 T2206C variant associated with FENO levels in asthmatic children using inhaled corticosteroids: the PACMAN study.

Karimi L, Vijverberg SJH, Farzan N, Ghanbari M, Verhamme KMC, Maitland-Van der Zee AH.

Clin Exp Allergy. 2019 Jul 15. doi: 10.1111/cea.13460. [Epub ahead of print]


Methylphenidate Treatment Initiated During Childhood Is Continued in Adulthood in Half of the Study Population.

Cheung K, Verhamme KMC, Herings R, Visser LE, Stricker BH.

J Child Adolesc Psychopharmacol. 2019 Jun 3. doi: 10.1089/cap.2018.0170. [Epub ahead of print]


Genome-wide association study of inhaled corticosteroid response in admixed children with asthma.

Hernandez-Pacheco N, Farzan N, Francis B, Karimi L, Repnik K, Vijverberg SJ, Soares P, Schieck M, Gorenjak M, Forno E, Eng C, Oh SS, Pérez-Méndez L, Berce V, Tavendale R, Samedy LA, Hunstman S, Hu D, Meade K, Farber HJ, Avila PC, Serebrisky D, Thyne SM, Brigino-Buenaventura E, Rodriguez-Cintron W, Sen S, Kumar R, Lenoir M, Rodriguez-Santana JR, Celedón JC, Mukhopadhyay S, Potočnik U, Pirmohamed M, Verhamme KM, Kabesch M, Palmer CNA, Hawcutt DB, Flores C, Maitland-van der Zee AH, Burchard EG, Pino-Yanes M.

Clin Exp Allergy. 2019 Jun;49(6):789-798. doi: 10.1111/cea.13354. Epub 2019 Feb 15.


COPD is associated with an increased risk of peripheral artery disease and mortality.

Terzikhan N, Lahousse L, Verhamme KMC, Franco OH, Ikram AM, Stricker BH, Brusselle GG.

ERJ Open Res. 2018 Dec 21;4(4). pii: 00086-2018. doi: 10.1183/23120541.00086-2018. eCollection 2018 Oct.


Antibiotic use in children with asthma: cohort study in UK and Dutch primary care databases.

Baan EJ, Janssens HM, Kerckaert T, Bindels PJE, de Jongste JC, Sturkenboom MCJM, Verhamme KMC.

BMJ Open. 2018 Nov 28;8(11):e022979. doi: 10.1136/bmjopen-2018-022979.


Development of the International Severe Asthma Registry (ISAR): A Modified Delphi Study.

Bulathsinhala L, Eleangovan N, Heaney LG, Menzies-Gow A, Gibson PG, Peters M, Hew M, van Boven JFM, Lehtimäki L, van Ganse E, Belhassen M, Harvey ES, Perez de Llano L, Maitland-van der Zee AH, Papadopoulos NG, FitzGerald JM, Porsbjerg C, Canonica GW, Backer V, Rhee CK, Verhamme KMC, Buhl R, Cosio BG, Carter V, Price C, Le T, Stagno d'Alcontres M, Gopalan G, Tran TN, Price D.

J Allergy Clin Immunol Pract. 2019 Feb;7(2):578-588.e2. doi: 10.1016/j.jaip.2018.08.016. Epub 2018 Sep 1.


17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use.

Farzan N, Vijverberg SJ, Hernandez-Pacheco N, Bel EHD, Berce V, Bønnelykke K, Bisgaard H, Burchard EG, Canino G, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Forno E, Francis B, Hawcutt DB, Herrera-Luis E, Kabesch M, Karimi L, Melén E, Mukhopadhyay S, Merid SK, Palmer CN, Pino-Yanes M, Pirmohamed M, Potočnik U, Repnik K, Schieck M, Sevelsted A, Sio YY, Smyth RL, Soares P, Söderhäll C, Tantisira KG, Tavendale R, Tse SM, Turner S, Verhamme KM, Maitland-van der Zee AH.

Allergy. 2018 Oct;73(10):2083-2088. doi: 10.1111/all.13499. Epub 2018 Jul 9. No abstract available.


Asthma and its comorbidities in middle-aged and older adults; the Rotterdam Study.

de Roos EW, Lahousse L, Verhamme KMC, Braunstahl GJ, Ikram MA, In 't Veen JCCM, Stricker BHC, Brusselle GGO.

Respir Med. 2018 Jun;139:6-12. doi: 10.1016/j.rmed.2018.04.006. Epub 2018 Apr 11.


Brand and generic use of inhalation medication and frequency of switching in children and adults: A population-based cohort study.

Engelkes M, van Blijderveen JC, Overbeek JA, Kuiper J, Herings RCM, Sturkenboom MCJM, de Jongste JC, Verhamme KMC, Janssens HM.

J Asthma. 2018 Oct;55(10):1086-1094. doi: 10.1080/02770903.2017.1396468. Epub 2017 Nov 29.


Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium.

Farzan N, Vijverberg SJ, Andiappan AK, Arianto L, Berce V, Blanca-López N, Bisgaard H, Bønnelykke K, Burchard EG, Campo P, Canino G, Carleton B, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Daley D, Den Dekker HT, Dijk FN, Duijts L, Flores C, Forno E, Hawcutt DB, Hernandez-Pacheco N, de Jongste JC, Kabesch M, Koppelman GH, Manolopoulos VG, Melén E, Mukhopadhyay S, Nilsson S, Palmer CN, Pino-Yanes M, Pirmohamed M, Potočnik U, Raaijmakers JA, Repnik K, Schieck M, Sio YY, Smyth RL, Szalai C, Tantisira KG, Turner S, van der Schee MP, Verhamme KM, Maitland-van der Zee AH.

Pharmacogenomics. 2017 Jul;18(10):931-943. doi: 10.2217/pgs-2017-0035. Epub 2017 Jun 22.


Pulmonary artery to aorta ratio and risk of all-cause mortality in the general population: the Rotterdam Study.

Terzikhan N, Bos D, Lahousse L, Wolff L, Verhamme KMC, Leening MJG, Felix JF, Gall H, Ghofrani HA, Franco OH, Ikram MA, Stricker BH, van der Lugt A, Brusselle G.

Eur Respir J. 2017 Jun 15;49(6). pii: 1602168. doi: 10.1183/13993003.02168-2016. Print 2017 Jun.


Antibiotic-Induced Liver Injury in Paediatric Outpatients: A Case-Control Study in Primary Care Databases.

Ferrajolo C, Verhamme KM, Trifirò G, 't Jong GW, Picelli G, Giaquinto C, Mazzaglia G, Stricker BH, Rossi F, Capuano A, Sturkenboom MC.

Drug Saf. 2017 Apr;40(4):305-315. doi: 10.1007/s40264-016-0493-y.


Evaluating the Safety Profile of Non-Active Implantable Medical Devices Compared with Medicines.

Pane J, Coloma PM, Verhamme KM, Sturkenboom MC, Rebollo I.

Drug Saf. 2017 Jan;40(1):37-47. doi: 10.1007/s40264-016-0474-1. Review.


Disease Systems Analysis of Bone Mineral Density and Bone Turnover Markers in Response to Alendronate, Placebo, and Washout in Postmenopausal Women.

Berkhout J, Stone JA, Verhamme KM, Danhof M, Post TM.

CPT Pharmacometrics Syst Pharmacol. 2016 Dec;5(12):656-664. doi: 10.1002/psp4.12135. Epub 2016 Nov 21.


Are proton-pump inhibitors harmful for the semen quality of men in couples who are planning pregnancy?

Huijgen NA, de Ridder MA, Verhamme KM, Dohle GR, Vanrolleghem AM, Sturkenboom MC, Laven JS, Steegers-Theunissen RP.

Fertil Steril. 2016 Dec;106(7):1666-1672.e2. doi: 10.1016/j.fertnstert.2016.09.010. Epub 2016 Oct 12.


Real life data on incidence and risk factors of severe asthma exacerbations in children in primary care.

Engelkes M, Janssens HM, de Ridder MA, Sturkenboom MC, de Jongste JC, Verhamme KM.

Respir Med. 2016 Oct;119:48-54. doi: 10.1016/j.rmed.2016.08.016. Epub 2016 Aug 23.


The variability in beta-cell function in placebo-treated subjects with type 2 diabetes: application of the weight-HbA1c-insulin-glucose (WHIG) model.

Duong JK, de Winter W, Choy S, Plock N, Naik H, Krauwinkel W, Visser SA, Verhamme KM, Sturkenboom MC, Stricker BH, Danhof M.

Br J Clin Pharmacol. 2017 Mar;83(3):487-497. doi: 10.1111/bcp.13144. Epub 2016 Nov 17.


Using Prescription Patterns in Primary Care to Derive New Quality Indicators for Childhood Community Antibiotic Prescribing.

de Bie S, Kaguelidou F, Verhamme KM, De Ridder M, Picelli G, Straus SM, Giaquinto C, Stricker BH, Bielicki J, Sharland M, Sturkenboom MC; ARPEC study.

Pediatr Infect Dis J. 2016 Dec;35(12):1317-1323.


Hypertension in older patients, a retrospective cohort study.

Blok CG, de Ridder MA, Verhamme KM, Moorman PW.

BMC Geriatr. 2016 Jul 19;16:142. doi: 10.1186/s12877-016-0316-0.


Prevalence and incidence of COPD in smokers and non-smokers: the Rotterdam Study.

Terzikhan N, Verhamme KM, Hofman A, Stricker BH, Brusselle GG, Lahousse L.

Eur J Epidemiol. 2016 Aug;31(8):785-92. doi: 10.1007/s10654-016-0132-z. Epub 2016 Mar 5.


Prescription patterns, adherence and characteristics of non-adherence in children with asthma in primary care.

Engelkes M, Janssens HM, de Jongste JC, Sturkenboom MC, Verhamme KM.

Pediatr Allergy Immunol. 2016 Mar;27(2):201-8. doi: 10.1111/pai.12507. Epub 2015 Dec 21.


Current needs in pediatric pharmacoepidemiology.

Lasky T, Artaman A, Czaja AS, Maruti SS, Osokogu OU, Verhamme KM, Sobel RE.

Pharmacoepidemiol Drug Saf. 2016 Jun;25(6):738-42. doi: 10.1002/pds.3985. Epub 2016 Feb 22.


Cardiac effects of current treatments of chronic obstructive pulmonary disease.

Lahousse L, Verhamme KM, Stricker BH, Brusselle GG.

Lancet Respir Med. 2016 Feb;4(2):149-64. doi: 10.1016/S2213-2600(15)00518-4. Epub 2016 Jan 12. Review.


Use of oral contraceptives in three European countries: a population-based multi-database study.

Bezemer ID, Verhamme KM, Gini R, Mosseveld M, Rijnbeek PR, Trifirò G, Sturkenboom MC, Penning-van Beest FJ, Herings RM.

Eur J Contracept Reprod Health Care. 2016;21(1):81-7. doi: 10.3109/13625187.2015.1102220. Epub 2015 Oct 22.


Application of a Systems Pharmacology-Based Placebo Population Model to Analyze Long-Term Data of Postmenopausal Osteoporosis.

Berkhout J, Stone JA, Verhamme KM, Stricker BH, Sturkenboom MC, Danhof M, Post TM.

CPT Pharmacometrics Syst Pharmacol. 2015 Sep;4(9):516-26. doi: 10.1002/psp4.12006. Epub 2015 Aug 22.


Pediatric Drug Safety Surveillance in FDA-AERS: A Description of Adverse Events from GRiP Project.

de Bie S, Ferrajolo C, Straus SM, Verhamme KM, Bonhoeffer J, Wong IC, Sturkenboom MC; GRiP network.

PLoS One. 2015 Jun 19;10(6):e0130399. doi: 10.1371/journal.pone.0130399. eCollection 2015.


Time trends in the incidence, prevalence and age at diagnosis of asthma in children.

Engelkes M, Janssens HM, de Ridder MA, de Jongste JC, Sturkenboom MC, Verhamme KM.

Pediatr Allergy Immunol. 2015 Jun;26(4):367-74. doi: 10.1111/pai.12376.


The role of electronic healthcare record databases in paediatric drug safety surveillance: a retrospective cohort study.

de Bie S, Coloma PM, Ferrajolo C, Verhamme KM, Trifirò G, Schuemie MJ, Straus SM, Gini R, Herings R, Mazzaglia G, Picelli G, Ghirardi A, Pedersen L, Stricker BH, van der Lei J, Sturkenboom MC; EU-ADR consortium.

Br J Clin Pharmacol. 2015 Aug;80(2):304-14. doi: 10.1111/bcp.12610. Epub 2015 May 20.


Prescription and indication trends of antidepressant drugs in the Netherlands between 1996 and 2012: a dynamic population-based study.

Noordam R, Aarts N, Verhamme KM, Sturkenboom MC, Stricker BH, Visser LE.

Eur J Clin Pharmacol. 2015 Mar;71(3):369-75. doi: 10.1007/s00228-014-1803-x. Epub 2015 Jan 6.


Medication adherence and the risk of severe asthma exacerbations: a systematic review.

Engelkes M, Janssens HM, de Jongste JC, Sturkenboom MC, Verhamme KM.

Eur Respir J. 2015 Feb;45(2):396-407. doi: 10.1183/09031936.00075614. Epub 2014 Oct 16. Review.


Sudden cardiac death is associated both with epilepsy and with use of antiepileptic medications.

Bardai A, Blom MT, van Noord C, Verhamme KM, Sturkenboom MC, Tan HL.

Heart. 2015 Jan;101(1):17-22. doi: 10.1136/heartjnl-2014-305664. Epub 2014 Jul 16.


Use of tiotropium Respimat versus HandiHaler and mortality in patients with COPD.

Verhamme KM, Sturkenboom MC, Brusselle GG.

Eur Respir J. 2014 Jun;43(6):1818-9. doi: 10.1183/09031936.00036314. No abstract available.


Risk of hyponatremia with diuretics: chlorthalidone versus hydrochlorothiazide.

van Blijderveen JC, Straus SM, Rodenburg EM, Zietse R, Stricker BH, Sturkenboom MC, Verhamme KM.

Am J Med. 2014 Aug;127(8):763-71. doi: 10.1016/j.amjmed.2014.04.014. Epub 2014 May 5.


Adherence to renal function monitoring guidelines in patients starting antihypertensive therapy with diuretics and RAAS inhibitors: a retrospective cohort study.

van Blijderveen JC, Straus SM, de Ridder MA, Stricker BH, Sturkenboom MC, Verhamme KM.

Drug Saf. 2014 May;37(5):369-77. doi: 10.1007/s40264-014-0160-0.


Tiotropium and the risk of death in COPD.

Verhamme KM, van Blijderveen N, Sturkenboom MC.

N Engl J Med. 2014 Jan 30;370(5):481-2. doi: 10.1056/NEJMc1314411. No abstract available.


Signal detection of potentially drug-induced acute liver injury in children using a multi-country healthcare database network.

Ferrajolo C, Coloma PM, Verhamme KM, Schuemie MJ, de Bie S, Gini R, Herings R, Mazzaglia G, Picelli G, Giaquinto C, Scotti L, Avillach P, Pedersen L, Rossi F, Capuano A, van der Lei J, Trifiró G, Sturkenboom MC; EU-ADR consortium.

Drug Saf. 2014 Feb;37(2):99-108. doi: 10.1007/s40264-013-0132-9.


A population-based study on the prevalence and incidence of chronic kidney disease in the Netherlands.

van Blijderveen JC, Straus SM, Zietse R, Stricker BH, Sturkenboom MC, Verhamme KM.

Int Urol Nephrol. 2014 Mar;46(3):583-92. doi: 10.1007/s11255-013-0563-3. Epub 2013 Sep 27.


Overanticoagulation is associated with renal function decline.

van Blijderveen JC, Verhamme KM, Zietse R, Visser LE, Romio SA, Buhre PN, Sturkenboom MC, Hofman A, Straus SM, Stricker BH.

J Nephrol. 2013 Jul-Aug;26(4):691-8. doi: 10.5301/jn.5000280. Epub 2013 Jul 1.


Automatic generation of case-detection algorithms to identify children with asthma from large electronic health record databases.

Afzal Z, Engelkes M, Verhamme KM, Janssens HM, Sturkenboom MC, Kors JA, Schuemie MJ.

Pharmacoepidemiol Drug Saf. 2013 Aug;22(8):826-33. doi: 10.1002/pds.3438. Epub 2013 Apr 17.


Idiopathic acute liver injury in paediatric outpatients: incidence and signal detection in two European countries.

Ferrajolo C, Verhamme KM, Trifirò G, 't Jong GW, Giaquinto C, Picelli G, Oteri A, de Bie S, Valkhoff VE, Schuemie MJ, Mazzaglia G, Cricelli C, Rossi F, Capuano A, Sturkenboom MC.

Drug Saf. 2013 Oct;36(10):1007-16. doi: 10.1007/s40264-013-0045-7.


Use of tiotropium Respimat Soft Mist Inhaler versus HandiHaler and mortality in patients with COPD.

Verhamme KM, Afonso A, Romio S, Stricker BC, Brusselle GG, Sturkenboom MC.

Eur Respir J. 2013 Sep;42(3):606-15. doi: 10.1183/09031936.00005813. Epub 2013 Mar 21.


Vaccine-based subgroup analysis in VigiBase: effect on sensitivity in paediatric signal detection.

de Bie S, Verhamme KM, Straus SM, Stricker BH, Sturkenboom MC.

Drug Saf. 2012 Apr 1;35(4):335-46. doi: 10.2165/11598120-000000000-00000.


The risk of new onset heart failure associated with dopamine agonist use in Parkinson's disease.

Mokhles MM, Trifirò G, Dieleman JP, Haag MD, van Soest EM, Verhamme KM, Mazzaglia G, Herings R, Luise Cd, Ross D, Brusselle G, Colao A, Haverkamp W, Schade R, Camp Gv, Zanettini R, Sturkenboom MC.

Pharmacol Res. 2012 Mar;65(3):358-64. doi: 10.1016/j.phrs.2011.11.009. Epub 2011 Nov 23.


Tiotropium Handihaler and the risk of cardio- or cerebrovascular events and mortality in patients with COPD.

Verhamme KM, Afonso AS, van Noord C, Haag MD, Koudstaal PJ, Brusselle GG, Sturkenboom MC.

Pulm Pharmacol Ther. 2012 Feb;25(1):19-26. doi: 10.1016/j.pupt.2011.10.004. Epub 2011 Oct 21.


Long-term follow-up after fractional flow reserve-guided treatment strategy in patients with an isolated proximal left anterior descending coronary artery stenosis.

Muller O, Mangiacapra F, Ntalianis A, Verhamme KM, Trana C, Hamilos M, Bartunek J, Vanderheyden M, Wyffels E, Heyndrickx GR, van Rooij FJ, Witteman JC, Hofman A, Wijns W, Barbato E, De Bruyne B.

JACC Cardiovasc Interv. 2011 Nov;4(11):1175-82. doi: 10.1016/j.jcin.2011.09.007. Epub 2011 Oct 26.


Mendelian randomization study of interleukin-6 in chronic obstructive pulmonary disease.

van Durme YM, Lahousse L, Verhamme KM, Stolk L, Eijgelsheim M, Loth DW, Uitterlinden AG, Breteler MM, Joos GF, Hofman A, Stricker BH, Brusselle GG.

Respiration. 2011;82(6):530-8. doi: 10.1159/000332336. Epub 2011 Oct 11.


COPD in the general population: prevalence, incidence and survival.

Afonso AS, Verhamme KM, Sturkenboom MC, Brusselle GG.

Respir Med. 2011 Dec;105(12):1872-84. doi: 10.1016/j.rmed.2011.06.012. Epub 2011 Aug 17.


Effects of safety warnings on prescription rates of cough and cold medicines in children below 2 years of age.

Sen EF, Verhamme KM, Felisi M, 't Jong GW, Giaquinto C, Picelli G, Ceci A, Sturkenboom MC; TEDDY European Network of Excellence.

Br J Clin Pharmacol. 2011 Jun;71(6):943-50. doi: 10.1111/j.1365-2125.2010.03860.x.


Drug-induced hepatic injury in children: a case/non-case study of suspected adverse drug reactions in VigiBase.

Ferrajolo C, Capuano A, Verhamme KM, Schuemie M, Rossi F, Stricker BH, Sturkenboom MC.

Br J Clin Pharmacol. 2010 Nov;70(5):721-8. doi: 10.1111/j.1365-2125.2010.03754.x.

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