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Items: 15

1.

The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity.

Billi AC, Gharaee-Kermani M, Fullmer J, Tsoi LC, Hill BD, Gruszka D, Ludwig J, Xing X, Estadt S, Wolf SJ, Rizvi SM, Berthier CC, Hodgin JB, Beamer MA, Sarkar MK, Liang Y, Uppala R, Shao S, Zeng C, Harms PW, Verhaegen ME, Voorhees JJ, Wen F, Ward NL, Dlugosz AA, Kahlenberg JM, Gudjonsson JE.

JCI Insight. 2019 Apr 18;4(8). pii: 127291. doi: 10.1172/jci.insight.127291. eCollection 2019 Apr 18.

2.

Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma.

Choi JE, Verhaegen ME, Yazdani S, Malik R, Harms PW, Mangelberger D, Tien J, Cao X, Wang Y, Cieślik M, Gurkan J, Yazdani M, Jing X, Juckette K, Su F, Wang R, Zhou B, Apel IJ, Wang S, Dlugosz AA, Chinnaiyan AM.

Neoplasia. 2019 Mar;21(3):322-330. doi: 10.1016/j.neo.2019.01.003. Epub 2019 Feb 21.

3.

Pharmacological Inhibition of Serine Palmitoyl Transferase and Sphingosine Kinase-1/-2 Inhibits Merkel Cell Carcinoma Cell Proliferation.

Bhat VK, Bernhart E, Plastira I, Fan K, Ghaffari-Tabrizi-Wizsy N, Wadsack C, Rechberger G, Eichmann T, Asslaber M, Spassova I, Verhaegen ME, Malle E, Becker JC, Sattler W.

J Invest Dermatol. 2019 Apr;139(4):807-817. doi: 10.1016/j.jid.2018.10.024. Epub 2018 Nov 3.

PMID:
30399362
4.

Circulating Cell-Free miR-375 as Surrogate Marker of Tumor Burden in Merkel Cell Carcinoma.

Fan K, Ritter C, Nghiem P, Blom A, Verhaegen ME, Dlugosz A, Ødum N, Woetmann A, Tothill RW, Hicks RJ, Sand M, Schrama D, Schadendorf D, Ugurel S, Becker JC.

Clin Cancer Res. 2018 Dec 1;24(23):5873-5882. doi: 10.1158/1078-0432.CCR-18-1184. Epub 2018 Jul 30.

5.

Tumor Architecture and Notch Signaling Modulate Drug Response in Basal Cell Carcinoma.

Eberl M, Mangelberger D, Swanson JB, Verhaegen ME, Harms PW, Frohm ML, Dlugosz AA, Wong SY.

Cancer Cell. 2018 Feb 12;33(2):229-243.e4. doi: 10.1016/j.ccell.2017.12.015. Epub 2018 Jan 27.

6.

Merkel Cell Polyomavirus Small T Antigen Initiates Merkel Cell Carcinoma-like Tumor Development in Mice.

Verhaegen ME, Mangelberger D, Harms PW, Eberl M, Wilbert DM, Meireles J, Bichakjian CK, Saunders TL, Wong SY, Dlugosz AA.

Cancer Res. 2017 Jun 15;77(12):3151-3157. doi: 10.1158/0008-5472.CAN-17-0035. Epub 2017 May 16.

7.

Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation.

Harms PW, Collie AM, Hovelson DH, Cani AK, Verhaegen ME, Patel RM, Fullen DR, Omata K, Dlugosz AA, Tomlins SA, Billings SD.

Mod Pathol. 2016 Mar;29(3):240-8. doi: 10.1038/modpathol.2015.154. Epub 2016 Jan 8.

8.

The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma.

Harms PW, Vats P, Verhaegen ME, Robinson DR, Wu YM, Dhanasekaran SM, Palanisamy N, Siddiqui J, Cao X, Su F, Wang R, Xiao H, Kunju LP, Mehra R, Tomlins SA, Fullen DR, Bichakjian CK, Johnson TM, Dlugosz AA, Chinnaiyan AM.

Cancer Res. 2015 Sep 15;75(18):3720-3727. doi: 10.1158/0008-5472.CAN-15-0702. Epub 2015 Aug 3.

9.

Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches.

Peterson SC, Eberl M, Vagnozzi AN, Belkadi A, Veniaminova NA, Verhaegen ME, Bichakjian CK, Ward NL, Dlugosz AA, Wong SY.

Cell Stem Cell. 2015 Apr 2;16(4):400-12. doi: 10.1016/j.stem.2015.02.006.

10.

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

Verhaegen ME, Mangelberger D, Harms PW, Vozheiko TD, Weick JW, Wilbert DM, Saunders TL, Ermilov AN, Bichakjian CK, Johnson TM, Imperiale MJ, Dlugosz AA.

J Invest Dermatol. 2015 May;135(5):1415-1424. doi: 10.1038/jid.2014.446. Epub 2014 Oct 14.

11.

Merkel cell carcinoma dependence on bcl-2 family members for survival.

Verhaegen ME, Mangelberger D, Weick JW, Vozheiko TD, Harms PW, Nash KT, Quintana E, Baciu P, Johnson TM, Bichakjian CK, Dlugosz AA.

J Invest Dermatol. 2014 Aug;134(8):2241-2250. doi: 10.1038/jid.2014.138. Epub 2014 Mar 10.

12.

Distinct gene expression profiles of viral- and nonviral-associated merkel cell carcinoma revealed by transcriptome analysis.

Harms PW, Patel RM, Verhaegen ME, Giordano TJ, Nash KT, Johnson CN, Daignault S, Thomas DG, Gudjonsson JE, Elder JT, Dlugosz AA, Johnson TM, Fullen DR, Bichakjian CK.

J Invest Dermatol. 2013 Apr;133(4):936-45. doi: 10.1038/jid.2012.445. Epub 2012 Dec 6.

13.

Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells.

Eberl M, Klingler S, Mangelberger D, Loipetzberger A, Damhofer H, Zoidl K, Schnidar H, Hache H, Bauer HC, Solca F, Hauser-Kronberger C, Ermilov AN, Verhaegen ME, Bichakjian CK, Dlugosz AA, Nietfeld W, Sibilia M, Lehrach H, Wierling C, Aberger F.

EMBO Mol Med. 2012 Mar;4(3):218-33. doi: 10.1002/emmm.201100201. Epub 2012 Feb 1.

14.

Huntingtin-interacting protein 1: a Merkel cell carcinoma marker that interacts with c-Kit.

Ames HM, Bichakjian CK, Liu GY, Oravecz-Wilson KI, Fullen DR, Verhaegen ME, Johnson TM, Dlugosz AA, Ross TS.

J Invest Dermatol. 2011 Oct;131(10):2113-20. doi: 10.1038/jid.2011.171. Epub 2011 Jun 23.

15.

Dendritic cell-based therapeutics for breast cancer.

Pilon-Thomas SA, Verhaegen ME, Mulé JJ.

Breast Dis. 2004;20:65-71. Review.

PMID:
15687708

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