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Items: 25

1.

Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats.

Rajani RM, Quick S, Ruigrok SR, Graham D, Harris SE, Verhaaren BFJ, Fornage M, Seshadri S, Atanur SS, Dominiczak AF, Smith C, Wardlaw JM, Williams A.

Sci Transl Med. 2018 Jul 4;10(448). pii: eaam9507. doi: 10.1126/scitranslmed.aam9507.

PMID:
29973407
2.

Carotid Plaque Morphology and Ischemic Vascular Brain Disease on MRI.

van den Bouwhuijsen QJA, Vernooij MW, Verhaaren BFJ, Vrooman HA, Niessen WJ, Krestin GP, Ikram MA, Franco OH, van der Lugt A.

AJNR Am J Neuroradiol. 2017 Sep;38(9):1776-1782. doi: 10.3174/ajnr.A5288. Epub 2017 Jul 13.

3.

Prevalence, Clinical Management, and Natural Course of Incidental Findings on Brain MR Images: The Population-based Rotterdam Scan Study.

Bos D, Poels MM, Adams HH, Akoudad S, Cremers LG, Zonneveld HI, Hoogendam YY, Verhaaren BF, Verlinden VJ, Verbruggen JG, Peymani A, Hofman A, Krestin GP, Vincent AJ, Feelders RA, Koudstaal PJ, van der Lugt A, Ikram MA, Vernooij MW.

Radiology. 2016 Nov;281(2):507-515. Epub 2016 Jun 23.

PMID:
27337027
4.

Markers of cerebral small vessel disease and severity of depression in the general population.

Direk N, Perez HS, Akoudad S, Verhaaren BF, Niessen WJ, Hofman A, Vernooij MW, Ikram MA, Tiemeier H.

Psychiatry Res Neuroimaging. 2016 Jul 30;253:1-6. doi: 10.1016/j.pscychresns.2016.05.002. Epub 2016 May 7.

PMID:
27254084
5.

White Matter Lesion Progression: Genome-Wide Search for Genetic Influences.

Hofer E, Cavalieri M, Bis JC, DeCarli C, Fornage M, Sigurdsson S, Srikanth V, Trompet S, Verhaaren BF, Wolf C, Yang Q, Adams HH, Amouyel P, Beiser A, Buckley BM, Callisaya M, Chauhan G, de Craen AJ, Dufouil C, van Duijn CM, Ford I, Freudenberger P, Gottesman RF, Gudnason V, Heiss G, Hofman A, Lumley T, Martinez O, Mazoyer B, Moran C, Niessen WJ, Phan T, Psaty BM, Satizabal CL, Sattar N, Schilling S, Shibata DK, Slagboom PE, Smith A, Stott DJ, Taylor KD, Thomson R, Töglhofer AM, Tzourio C, van Buchem M, Wang J, Westendorp RG, Windham BG, Vernooij MW, Zijdenbos A, Beare R, Debette S, Ikram MA, Jukema JW, Launer LJ, Longstreth WT Jr, Mosley TH, Seshadri S, Schmidt H, Schmidt R; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium.

Stroke. 2015 Nov;46(11):3048-57. doi: 10.1161/STROKEAHA.115.009252. Epub 2015 Oct 8.

6.

Small cortical infarcts: prevalence, determinants, and cognitive correlates in the general population.

Riba-Llena I, Koek M, Verhaaren BF, Vrooman HA, van der Lugt A, Hofman A, Ikram MA, Vernooij MW.

Int J Stroke. 2015 Oct;10 Suppl A100:18-24. doi: 10.1111/ijs.12543. Epub 2015 Jun 4.

PMID:
26043763
7.

Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.

Verhaaren BF, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, van Buchem MA, van der Grond J, Smith AV, Hegenscheid K, Aggarwal NT, de Andrade M, Atkinson EJ, Beekman M, Beiser AS, Blanton SH, Boerwinkle E, Brickman AM, Bryan RN, Chauhan G, Chen CP, Chouraki V, de Craen AJ, Crivello F, Deary IJ, Deelen J, De Jager PL, Dufouil C, Elkind MS, Evans DA, Freudenberger P, Gottesman RF, Guðnason V, Habes M, Heckbert SR, Heiss G, Hilal S, Hofer E, Hofman A, Ibrahim-Verbaas CA, Knopman DS, Lewis CE, Liao J, Liewald DC, Luciano M, van der Lugt A, Martinez OO, Mayeux R, Mazoyer B, Nalls M, Nauck M, Niessen WJ, Oostra BA, Psaty BM, Rice KM, Rotter JI, von Sarnowski B, Schmidt H, Schreiner PJ, Schuur M, Sidney SS, Sigurdsson S, Slagboom PE, Stott DJ, van Swieten JC, Teumer A, Töglhofer AM, Traylor M, Trompet S, Turner ST, Tzourio C, Uh HW, Uitterlinden AG, Vernooij MW, Wang JJ, Wong TY, Wardlaw JM, Windham BG, Wittfeld K, Wolf C, Wright CB, Yang Q, Zhao W, Zijdenbos A, Jukema JW, Sacco RL, Kardia SL, Amouyel P, Mosley TH, Longstreth WT Jr, DeCarli CC, van Duijn CM, Schmidt R, Launer LJ, Grabe HJ, Seshadri SS, Ikram MA, Fornage M.

Circ Cardiovasc Genet. 2015 Apr;8(2):398-409. doi: 10.1161/CIRCGENETICS.114.000858. Epub 2015 Feb 7.

8.

Cognition, structural brain changes and complicated grief. A population-based study.

Saavedra Pérez HC, Ikram MA, Direk N, Prigerson HG, Freak-Poli R, Verhaaren BF, Hofman A, Vernooij M, Tiemeier H.

Psychol Med. 2015 May;45(7):1389-99. doi: 10.1017/S0033291714002499. Epub 2014 Nov 3.

PMID:
25363662
9.

Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium.

Bis JC, DeStefano A, Liu X, Brody JA, Choi SH, Verhaaren BF, Debette S, Ikram MA, Shahar E, Butler KR Jr, Gottesman RF, Muzny D, Kovar CL, Psaty BM, Hofman A, Lumley T, Gupta M, Wolf PA, van Duijn C, Gibbs RA, Mosley TH, Longstreth WT Jr, Boerwinkle E, Seshadri S, Fornage M.

PLoS One. 2014 Jun 24;9(6):e99798. doi: 10.1371/journal.pone.0099798. eCollection 2014.

10.

TMEM106B influences volume of left-sided temporal lobe and interhemispheric structures in the general population.

Adams HH, Verhaaren BF, Vrooman HA, Uitterlinden AG, Hofman A, van Duijn CM, van der Lugt A, Niessen WJ, Vernooij MW, Ikram MA.

Biol Psychiatry. 2014 Sep 15;76(6):503-8. doi: 10.1016/j.biopsych.2014.03.006. Epub 2014 Mar 14.

PMID:
24731779
11.

Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies.

Malik R, Bevan S, Nalls MA, Holliday EG, Devan WJ, Cheng YC, Ibrahim-Verbaas CA, Verhaaren BF, Bis JC, Joon AY, de Stefano AL, Fornage M, Psaty BM, Ikram MA, Launer LJ, van Duijn CM, Sharma P, Mitchell BD, Rosand J, Meschia JF, Levi C, Rothwell PM, Sudlow C, Markus HS, Seshadri S, Dichgans M; Wellcome Trust Case Control Consortium 2.

Stroke. 2014 Feb;45(2):394-402. doi: 10.1161/STROKEAHA.113.002938. Epub 2014 Jan 16.

12.

Rating method for dilated Virchow-Robin spaces on magnetic resonance imaging.

Adams HH, Cavalieri M, Verhaaren BF, Bos D, van der Lugt A, Enzinger C, Vernooij MW, Schmidt R, Ikram MA.

Stroke. 2013 Jun;44(6):1732-5. doi: 10.1161/STROKEAHA.111.000620. Epub 2013 May 2.

PMID:
23640831
13.

The relation of uric acid to brain atrophy and cognition: the Rotterdam Scan Study.

Verhaaren BF, Vernooij MW, Dehghan A, Vrooman HA, de Boer R, Hofman A, Witteman JC, Niessen WJ, Breteler MM, van der Lugt A, Ikram MA.

Neuroepidemiology. 2013;41(1):29-34. doi: 10.1159/000346606. Epub 2013 Mar 19.

PMID:
23548762
14.

High blood pressure and cerebral white matter lesion progression in the general population.

Verhaaren BF, Vernooij MW, de Boer R, Hofman A, Niessen WJ, van der Lugt A, Ikram MA.

Hypertension. 2013 Jun;61(6):1354-9. doi: 10.1161/HYPERTENSIONAHA.111.00430. Epub 2013 Mar 25.

PMID:
23529163
15.

Changes in normal-appearing white matter precede development of white matter lesions.

de Groot M, Verhaaren BF, de Boer R, Klein S, Hofman A, van der Lugt A, Ikram MA, Niessen WJ, Vernooij MW.

Stroke. 2013 Apr;44(4):1037-42. doi: 10.1161/STROKEAHA.112.680223. Epub 2013 Feb 21.

PMID:
23429507
16.

Genetic loci for coronary calcification and serum lipids relate to aortic and carotid calcification.

Bos D, Ikram MA, Isaacs A, Verhaaren BF, Hofman A, van Duijn CM, Witteman JC, van der Lugt A, Vernooij MW.

Circ Cardiovasc Genet. 2013 Feb;6(1):47-53. doi: 10.1161/CIRCGENETICS.112.963934. Epub 2012 Dec 16.

PMID:
23247144
17.

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke.

Holliday EG, Maguire JM, Evans TJ, Koblar SA, Jannes J, Sturm JW, Hankey GJ, Baker R, Golledge J, Parsons MW, Malik R, McEvoy M, Biros E, Lewis MD, Lincz LF, Peel R, Oldmeadow C, Smith W, Moscato P, Barlera S, Bevan S, Bis JC, Boerwinkle E, Boncoraglio GB, Brott TG, Brown RD Jr, Cheng YC, Cole JW, Cotlarciuc I, Devan WJ, Fornage M, Furie KL, Grétarsdóttir S, Gschwendtner A, Ikram MA, Longstreth WT Jr, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Parati EA, Psaty BM, Sharma P, Stefansson K, Thorleifsson G, Thorsteinsdottir U, Traylor M, Verhaaren BF, Wiggins KL, Worrall BB, Sudlow C, Rothwell PM, Farrall M, Dichgans M, Rosand J, Markus HS, Scott RJ, Levi C, Attia J; Australian Stroke Genetics Collaborative; International Stroke Genetics Consortium; Wellcome Trust Case Control Consortium 2.

Nat Genet. 2012 Oct;44(10):1147-51. doi: 10.1038/ng.2397. Epub 2012 Sep 2.

18.

Alzheimer's disease genes and cognition in the nondemented general population.

Verhaaren BF, Vernooij MW, Koudstaal PJ, Uitterlinden AG, van Duijn CM, Hofman A, Breteler MM, Ikram MA.

Biol Psychiatry. 2013 Mar 1;73(5):429-34. doi: 10.1016/j.biopsych.2012.04.009. Epub 2012 May 15.

PMID:
22592056
19.

Is dementia incidence declining?: Trends in dementia incidence since 1990 in the Rotterdam Study.

Schrijvers EM, Verhaaren BF, Koudstaal PJ, Hofman A, Ikram MA, Breteler MM.

Neurology. 2012 May 8;78(19):1456-63. doi: 10.1212/WNL.0b013e3182553be6. Epub 2012 May 2.

PMID:
22551732
20.

Atherosclerotic calcification relates to cognitive function and to brain changes on magnetic resonance imaging.

Bos D, Vernooij MW, Elias-Smale SE, Verhaaren BF, Vrooman HA, Hofman A, Niessen WJ, Witteman JC, van der Lugt A, Ikram MA.

Alzheimers Dement. 2012 Oct;8(5 Suppl):S104-11. doi: 10.1016/j.jalz.2012.01.008. Epub 2012 Apr 25.

21.

Common variants at 12q14 and 12q24 are associated with hippocampal volume.

Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR Jr, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM; Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT Jr, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium.

Nat Genet. 2012 Apr 15;44(5):545-51. doi: 10.1038/ng.2237.

22.

Genome-wide profiling of blood pressure in adults and children.

Taal HR, Verwoert GC, Demirkan A, Janssens AC, Rice K, Ehret G, Smith AV, Verhaaren BF, Witteman JC, Hofman A, Vernooij MW, Uitterlinden AG, Rivadeneira F, Ikram MA, Levy D, van der Heijden AJ; Cohort for Heart and Aging Research in Genome Epidemiology and Early Genetics and Lifecourse Epidemiology consortia, Jaddoe VW, van Duijn CM.

Hypertension. 2012 Feb;59(2):241-7. doi: 10.1161/HYPERTENSIONAHA.111.179481. Epub 2011 Dec 27.

23.

Automated measurement of local white matter lesion volume.

van der Lijn F, Verhaaren BF, Ikram MA, Klein S, de Bruijne M, Vrooman HA, Vernooij MW, Hammers A, Rueckert D, van der Lugt A, Breteler MM, Niessen WJ.

Neuroimage. 2012 Feb 15;59(4):3901-8. doi: 10.1016/j.neuroimage.2011.11.021. Epub 2011 Nov 11.

PMID:
22116036
24.

Replication study of chr17q25 with cerebral white matter lesion volume.

Verhaaren BF, de Boer R, Vernooij MW, Rivadeneira F, Uitterlinden AG, Hofman A, Krestin GP, van der Lugt A, Niessen WJ, Breteler MM, Ikram MA.

Stroke. 2011 Nov;42(11):3297-9. doi: 10.1161/STROKEAHA.111.623090. Epub 2011 Aug 25.

PMID:
21868733
25.

The pathophysiology of abdominal aortic aneurysm growth: corresponding and discordant inflammatory and proteolytic processes in abdominal aortic and popliteal artery aneurysms.

Abdul-Hussien H, Hanemaaijer R, Kleemann R, Verhaaren BF, van Bockel JH, Lindeman JH.

J Vasc Surg. 2010 Jun;51(6):1479-87. doi: 10.1016/j.jvs.2010.01.057.

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