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Items: 19


Endosomal-Lysosomal Cholesterol Sequestration by U18666A Differentially Regulates Amyloid Precursor Protein (APP) Metabolism in Normal and APP-Overexpressing Cells.

Chung J, Phukan G, Vergote D, Mohamed A, Maulik M, Stahn M, Andrew RJ, Thinakaran G, Posse de Chaves E, Kar S.

Mol Cell Biol. 2018 May 15;38(11). pii: e00529-17. doi: 10.1128/MCB.00529-17. Print 2018 Jun 1.


The Effects of Extracellular Serum Concentration on APP Processing in Npc1-Deficient APP-Overexpressing N2a Cells.

Maulik M, Vergote D, Phukan G, Chung J, Thinakaran G, Kar S.

Mol Neurobiol. 2018 Jul;55(7):5757-5766. doi: 10.1007/s12035-017-0799-5. Epub 2017 Oct 19.


Alzheimer's Genetic Risk Intensifies Neurocognitive Slowing Associated with Diabetes in Non-Demented Older Adults.

McFall GP, Wiebe SA, Vergote D, Anstey KJ, Dixon RA.

Alzheimers Dement (Amst). 2015 Dec;1(4):395-402.


Vascular Health and Genetic Risk Affect Mild Cognitive Impairment Status and 4-Year Stability: Evidence From the Victoria Longitudinal Study.

DeCarlo CA, MacDonald SW, Vergote D, Jhamandas J, Westaway D, Dixon RA.

J Gerontol B Psychol Sci Soc Sci. 2016 Nov;71(6):1004-1014. Epub 2015 Sep 11.


ApoE and pulse pressure interactively influence level and change in the aging of episodic memory: Protective effects among ε2 carriers.

McFall GP, Wiebe SA, Vergote D, Westaway D, Jhamandas J, Bäckman L, Dixon RA.

Neuropsychology. 2015 May;29(3):388-401. doi: 10.1037/neu0000150. Epub 2014 Dec 1.


APOE and COMT polymorphisms are complementary biomarkers of status, stability, and transitions in normal aging and early mild cognitive impairment.

Dixon RA, DeCarlo CA, MacDonald SW, Vergote D, Jhamandas J, Westaway D.

Front Aging Neurosci. 2014 Sep 5;6:236. doi: 10.3389/fnagi.2014.00236. eCollection 2014.


Synergistic associations of catechol-O-methyltransferase and brain-derived neurotrophic factor with executive function in aging are selective and modified by apolipoprotein E.

Sapkota S, Vergote D, Westaway D, Jhamandas J, Dixon RA.

Neurobiol Aging. 2015 Jan;36(1):249-56. doi: 10.1016/j.neurobiolaging.2014.06.020. Epub 2014 Jun 20.


IDE (rs6583817) polymorphism and pulse pressure are independently and interactively associated with level and change in executive function in older adults.

McFall GP, Wiebe SA, Vergote D, Jhamandas J, Westaway D, Dixon RA.

Psychol Aging. 2014 Jun;29(2):418-430. doi: 10.1037/a0034656. Epub 2014 Mar 24.


IDE (rs6583817) polymorphism and type 2 diabetes differentially modify executive function in older adults.

McFall GP, Wiebe SA, Vergote D, Westaway D, Jhamandas J, Dixon RA.

Neurobiol Aging. 2013 Sep;34(9):2208-16. doi: 10.1016/j.neurobiolaging.2013.03.010. Epub 2013 Apr 16.


Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts.

Vardarajan B, Vergote D, Tissir F, Logue M, Yang J, Daude N, Ando K, Rogaeva E, Lee J, Cheng R, Brion JP, Ghani M, Shi B, Baldwin CT, Kar S, Mayeux R, Fraser P, Goffinet AM, George-Hyslop PS, Farrer LA, Westaway D.

Mol Neurodegener. 2013 Feb 15;8:10. doi: 10.1186/1750-1326-8-10.


Role of cathepsin D in U18666A-induced neuronal cell death: potential implication in Niemann-Pick type C disease pathogenesis.

Amritraj A, Wang Y, Revett TJ, Vergote D, Westaway D, Kar S.

J Biol Chem. 2013 Feb 1;288(5):3136-52. doi: 10.1074/jbc.M112.412460. Epub 2012 Dec 17.


Morphological and functional characterization of leech circulating blood cells: role in immunity and neural repair.

Boidin-Wichlacz C, Vergote D, Slomianny C, Jouy N, Salzet M, Tasiemski A.

Cell Mol Life Sci. 2012 May;69(10):1717-31. doi: 10.1007/s00018-011-0897-x. Epub 2011 Dec 11.


CXCR3 activation by lentivirus infection suppresses neuronal autophagy: neuroprotective effects of antiretroviral therapy.

Zhu Y, Vergote D, Pardo C, Noorbakhsh F, McArthur JC, Hollenberg MD, Overall CM, Power C.

FASEB J. 2009 Sep;23(9):2928-41. doi: 10.1096/fj.08-128819. Epub 2009 Apr 20.


Glucocorticoids regulate innate immunity in a model of multiple sclerosis: reciprocal interactions between the A1 adenosine receptor and beta-arrestin-1 in monocytoid cells.

Tsutsui S, Vergote D, Shariat N, Warren K, Ferguson SS, Power C.

FASEB J. 2008 Mar;22(3):786-96. Epub 2007 Oct 26.


Proteolytic processing of SDF-1alpha reveals a change in receptor specificity mediating HIV-associated neurodegeneration.

Vergote D, Butler GS, Ooms M, Cox JH, Silva C, Hollenberg MD, Jhamandas JH, Overall CM, Power C.

Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19182-7. Epub 2006 Dec 5.


Proteome modifications of the medicinal leech nervous system under bacterial challenge.

Vergote D, Macagno ER, Salzet M, Sautière PE.

Proteomics. 2006 Sep;6(17):4817-25.


Characterisation of proteins differentially present in the plasma of Biomphalaria glabrata susceptible or resistant to Echinostoma caproni.

Vergote D, Bouchut A, Sautière PE, Roger E, Galinier R, Rognon A, Coustau C, Salzet M, Mitta G.

Int J Parasitol. 2005 Feb;35(2):215-24. Epub 2004 Dec 15.


Up-regulation of neurohemerythrin expression in the central nervous system of the medicinal leech, Hirudo medicinalis, following septic injury.

Vergote D, Sautière PE, Vandenbulcke F, Vieau D, Mitta G, Macagno ER, Salzet M.

J Biol Chem. 2004 Oct 15;279(42):43828-37. Epub 2004 Jul 16.


(-)-Epigallocatechin (EGC) of green tea induces apoptosis of human breast cancer cells but not of their normal counterparts.

Vergote D, Cren-Olivé C, Chopin V, Toillon RA, Rolando C, Hondermarck H, Le Bourhis X.

Breast Cancer Res Treat. 2002 Dec;76(3):195-201.


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