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Items: 9


Novel Potent Capsid Assembly Modulators Regulate Multiple Steps of the Hepatitis B Virus Life Cycle.

Lahlali T, Berke JM, Vergauwen K, Foca A, Vandyck K, Pauwels F, Zoulim F, Durantel D.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e00835-18. doi: 10.1128/AAC.00835-18. Print 2018 Oct.


Synthesis and Evaluation of N-Phenyl-3-sulfamoyl-benzamide Derivatives as Capsid Assembly Modulators Inhibiting Hepatitis B Virus (HBV).

Vandyck K, Rombouts G, Stoops B, Tahri A, Vos A, Verschueren W, Wu Y, Yang J, Hou F, Huang B, Vergauwen K, Dehertogh P, Berke JM, Raboisson P.

J Med Chem. 2018 Jul 26;61(14):6247-6260. doi: 10.1021/acs.jmedchem.8b00654. Epub 2018 Jul 3.


Antiviral profiling of the capsid assembly modulator BAY41-4109 on full-length HBV genotype A-H clinical isolates and core site-directed mutants in vitro.

Berke JM, Tan Y, Verbinnen T, Dehertogh P, Vergauwen K, Vos A, Lenz O, Pauwels F.

Antiviral Res. 2017 Aug;144:205-215. doi: 10.1016/j.antiviral.2017.06.016. Epub 2017 Jun 21.


Capsid Assembly Modulators Have a Dual Mechanism of Action in Primary Human Hepatocytes Infected with Hepatitis B Virus.

Berke JM, Dehertogh P, Vergauwen K, Van Damme E, Mostmans W, Vandyck K, Pauwels F.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00560-17. doi: 10.1128/AAC.00560-17. Print 2017 Aug.


Assessment of activity limitations and participation restrictions with persons with chronic fatigue syndrome: a systematic review.

Vergauwen K, Huijnen IP, Kos D, Van de Velde D, van Eupen I, Meeus M.

Disabil Rehabil. 2015;37(19):1706-16. doi: 10.3109/09638288.2014.978507. Epub 2014 Nov 3. Review.


Novel antibiotics targeting respiratory ATP synthesis in Gram-positive pathogenic bacteria.

Balemans W, Vranckx L, Lounis N, Pop O, Guillemont J, Vergauwen K, Mol S, Gilissen R, Motte M, Lançois D, De Bolle M, Bonroy K, Lill H, Andries K, Bald D, Koul A.

Antimicrob Agents Chemother. 2012 Aug;56(8):4131-9. doi: 10.1128/AAC.00273-12. Epub 2012 May 21.


Selectivity of TMC207 towards mycobacterial ATP synthase compared with that towards the eukaryotic homologue.

Haagsma AC, Abdillahi-Ibrahim R, Wagner MJ, Krab K, Vergauwen K, Guillemont J, Andries K, Lill H, Koul A, Bald D.

Antimicrob Agents Chemother. 2009 Mar;53(3):1290-2. doi: 10.1128/AAC.01393-08. Epub 2008 Dec 15.


Diarylquinolines are bactericidal for dormant mycobacteria as a result of disturbed ATP homeostasis.

Koul A, Vranckx L, Dendouga N, Balemans W, Van den Wyngaert I, Vergauwen K, Göhlmann HW, Willebrords R, Poncelet A, Guillemont J, Bald D, Andries K.

J Biol Chem. 2008 Sep 12;283(37):25273-80. doi: 10.1074/jbc.M803899200. Epub 2008 Jul 14.


Diarylquinolines target subunit c of mycobacterial ATP synthase.

Koul A, Dendouga N, Vergauwen K, Molenberghs B, Vranckx L, Willebrords R, Ristic Z, Lill H, Dorange I, Guillemont J, Bald D, Andries K.

Nat Chem Biol. 2007 Jun;3(6):323-4. Epub 2007 May 13.


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