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Items: 1 to 50 of 388

1.

Radiation Oncology. Optimal Health for All, Together. ESTRO vision, 2030.

Lievens Y, Ricardi U, Poortmans P, Verellen D, Gasparotto C, Verfaillie C, Cortese AJ.

Radiother Oncol. 2019 Jul;136:86-97. doi: 10.1016/j.radonc.2019.03.031. Epub 2019 Apr 11.

PMID:
31015134
2.

Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA.

Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ.

Cell Rep. 2019 Mar 26;26(13):3522-3536.e5. doi: 10.1016/j.celrep.2019.02.097.

3.

Breast cancer cells rely on environmental pyruvate to shape the metastatic niche.

Elia I, Rossi M, Stegen S, Broekaert D, Doglioni G, van Gorsel M, Boon R, Escalona-Noguero C, Torrekens S, Verfaillie C, Verbeken E, Carmeliet G, Fendt SM.

Nature. 2019 Apr;568(7750):117-121. doi: 10.1038/s41586-019-0977-x. Epub 2019 Feb 27.

PMID:
30814728
4.

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity.

Vriens K, Christen S, Parik S, Broekaert D, Yoshinaga K, Talebi A, Dehairs J, Escalona-Noguero C, Schmieder R, Cornfield T, Charlton C, Romero-Pérez L, Rossi M, Rinaldi G, Orth MF, Boon R, Kerstens A, Kwan SY, Faubert B, Méndez-Lucas A, Kopitz CC, Chen T, Fernandez-Garcia J, Duarte JAG, Schmitz AA, Steigemann P, Najimi M, Hägebarth A, Van Ginderachter JA, Sokal E, Gotoh N, Wong KK, Verfaillie C, Derua R, Munck S, Yuneva M, Beretta L, DeBerardinis RJ, Swinnen JV, Hodson L, Cassiman D, Verslype C, Christian S, Grünewald S, Grünewald TGP, Fendt SM.

Nature. 2019 Feb;566(7744):403-406. doi: 10.1038/s41586-019-0904-1. Epub 2019 Feb 6.

PMID:
30728499
5.

Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals.

Tricot T, Helsen N, Kaptein SJF, Neyts J, Verfaillie CM.

PLoS One. 2018 Dec 19;13(12):e0209097. doi: 10.1371/journal.pone.0209097. eCollection 2018.

6.

The Impact of Integrin β2 on Granulocyte/Macrophage Progenitor Proliferation.

Zhang LJ, Yan C, Schouteden S, Ma XJ, Zhao D, Peters T, Verfaillie CM, Feng YM.

Stem Cells. 2019 Mar;37(3):430-440. doi: 10.1002/stem.2961. Epub 2019 Feb 7.

PMID:
30537419
7.

Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2.

Claes C, Van Den Daele J, Boon R, Schouteden S, Colombo A, Monasor LS, Fiers M, Ordovás L, Nami F, Bohrmann B, Tahirovic S, De Strooper B, Verfaillie CM.

Alzheimers Dement. 2019 Mar;15(3):453-464. doi: 10.1016/j.jalz.2018.09.006. Epub 2018 Nov 12.

8.

Evaluation of the Seegene Allplex™ Respiratory Panel for diagnosis of acute respiratory tract infections.

Vandendriessche S, Padalko E, Wollants E, Verfaillie C, Verhasselt B, Coorevits L.

Acta Clin Belg. 2018 Oct 11:1-7. doi: 10.1080/17843286.2018.1531605. [Epub ahead of print]

PMID:
30307378
9.

Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis.

Coll M, Perea L, Boon R, Leite SB, Vallverdú J, Mannaerts I, Smout A, El Taghdouini A, Blaya D, Rodrigo-Torres D, Graupera I, Aguilar-Bravo B, Chesne C, Najimi M, Sokal E, Lozano JJ, van Grunsven LA, Verfaillie CM, Sancho-Bru P.

Cell Stem Cell. 2018 Jul 5;23(1):101-113.e7. doi: 10.1016/j.stem.2018.05.027. Epub 2018 Jun 28.

10.

Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration.

García-León JA, Cabrera-Socorro A, Eggermont K, Swijsen A, Terryn J, Fazal R, Nami F, Ordovás L, Quiles A, Lluis F, Serneels L, Wierda K, Sierksma A, Kreir M, Pestana F, Van Damme P, De Strooper B, Thorrez L, Ebneth A, Verfaillie CM.

Alzheimers Dement. 2018 Oct;14(10):1261-1280. doi: 10.1016/j.jalz.2018.05.007. Epub 2018 Jul 20.

11.

Energy Producing Metabolic Pathways in Functional Regulation of the Hematopoietic Stem Cells.

Roy IM, Biswas A, Verfaillie C, Khurana S.

IUBMB Life. 2018 Jul;70(7):612-624. doi: 10.1002/iub.1870. Review.

12.

In Vitro Pluripotent Stem Cell Differentiation to Hepatocyte Ceases Further Maturation at an Equivalent Stage of E15 in Mouse Embryonic Liver Development.

Raju R, Chau D, Notelaers T, Myers CL, Verfaillie CM, Hu WS.

Stem Cells Dev. 2018 Jul 1;27(13):910-921. doi: 10.1089/scd.2017.0270. Epub 2018 May 31.

PMID:
29851366
13.

The human somatostatin receptor type 2 as an imaging and suicide reporter gene for pluripotent stem cell-derived therapy of myocardial infarction.

Neyrinck K, Breuls N, Holvoet B, Oosterlinck W, Wolfs E, Vanbilloen H, Gheysens O, Duelen R, Gsell W, Lambrichts I, Himmelreich U, Verfaillie CM, Sampaolesi M, Deroose CM.

Theranostics. 2018 Apr 14;8(10):2799-2813. doi: 10.7150/thno.22980. eCollection 2018.

14.

Generation of hepatocyte- and endocrine pancreatic-like cells from human induced endodermal progenitor cells.

Sambathkumar R, Akkerman R, Dastidar S, Roelandt P, Kumar M, Bajaj M, Mestre Rosa AR, Helsen N, Vanslembrouck V, Kalo E, Khurana S, Laureys J, Gysemans C, Faas MM, de Vos P, Verfaillie CM.

PLoS One. 2018 May 11;13(5):e0197046. doi: 10.1371/journal.pone.0197046. eCollection 2018.

15.

Strategies for In Vivo Genome Editing in Nondividing Cells.

Nami F, Basiri M, Satarian L, Curtiss C, Baharvand H, Verfaillie C.

Trends Biotechnol. 2018 Aug;36(8):770-786. doi: 10.1016/j.tibtech.2018.03.004. Epub 2018 Apr 21. Review.

PMID:
29685818
16.

Learning radiation oncology in Europe: Results of the ESTRO multidisciplinary survey.

Bibault JE, Franco P, Borst GR, Van Elmpt W, Thorwhart D, Schmid MP, Rouschop KMA, Spalek M, Mullaney L, Redalen KR, Dubois L, Verfaillie C, Eriksen JG.

Clin Transl Radiat Oncol. 2018 Feb 8;9:61-67. doi: 10.1016/j.ctro.2018.02.001. eCollection 2018 Feb.

17.

Recent advances in lineage differentiation from stem cells: hurdles and opportunities?

Terryn J, Tricot T, Gajjar M, Verfaillie C.

F1000Res. 2018 Feb 23;7:220. doi: 10.12688/f1000research.12596.1. eCollection 2018. Review.

18.

Multipotent Adult Progenitor Cells Support Lymphatic Regeneration at Multiple Anatomical Levels during Wound Healing and Lymphedema.

Beerens M, Aranguren XL, Hendrickx B, Dheedene W, Dresselaers T, Himmelreich U, Verfaillie C, Luttun A.

Sci Rep. 2018 Mar 1;8(1):3852. doi: 10.1038/s41598-018-21610-8.

19.

PFN2 and GAMT as common molecular determinants of axonal Charcot-Marie-Tooth disease.

Juneja M, Azmi A, Baets J, Roos A, Jennings MJ, Saveri P, Pisciotta C, Bernard-Marissal N, Schneider BL, Verfaillie C, Chrast R, Seeman P, Hahn AF, de Jonghe P, Maudsley S, Horvath R, Pareyson D, Timmerman V.

J Neurol Neurosurg Psychiatry. 2018 Aug;89(8):870-878. doi: 10.1136/jnnp-2017-317562. Epub 2018 Feb 15.

PMID:
29449460
20.

Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition.

Ordovás L, Boon R, Pistoni M, Chen Y, Wolfs E, Guo W, Sambathkumar R, Bobis-Wozowicz S, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Eggermont K, Vanslembrouck V, Schmidt BZ, Raitano S, Van Den Bosch L, Nahmias Y, Cathomen T, Struys T, Verfaillie CM.

Stem Cell Reports. 2018 Feb 13;10(2):673. doi: 10.1016/j.stemcr.2018.01.034. No abstract available.

21.

Folic Acid Exposure Rescues Spina Bifida Aperta Phenotypes in Human Induced Pluripotent Stem Cell Model.

Sahakyan V, Duelen R, Tam WL, Roberts SJ, Grosemans H, Berckmans P, Ceccarelli G, Pelizzo G, Broccoli V, Deprest J, Luyten FP, Verfaillie CM, Sampaolesi M.

Sci Rep. 2018 Feb 13;8(1):2942. doi: 10.1038/s41598-018-21103-8.

22.

Generating tissue-resident macrophages from pluripotent stem cells: Lessons learned from microglia.

Claes C, Van den Daele J, Verfaillie CM.

Cell Immunol. 2018 Aug;330:60-67. doi: 10.1016/j.cellimm.2018.01.019. Epub 2018 Feb 2. Review.

PMID:
29433896
23.

SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells.

García-León JA, Kumar M, Boon R, Chau D, One J, Wolfs E, Eggermont K, Berckmans P, Gunhanlar N, de Vrij F, Lendemeijer B, Pavie B, Corthout N, Kushner SA, Dávila JC, Lambrichts I, Hu WS, Verfaillie CM.

Stem Cell Reports. 2018 Feb 13;10(2):655-672. doi: 10.1016/j.stemcr.2017.12.014. Epub 2018 Jan 11.

24.

Human intestinal epithelium in a dish: Current models for research into gastrointestinal pathophysiology.

Noben M, Vanhove W, Arnauts K, Santo Ramalho A, Van Assche G, Vermeire S, Verfaillie C, Ferrante M.

United European Gastroenterol J. 2017 Dec;5(8):1073-1081. doi: 10.1177/2050640617722903. Epub 2017 Jul 21. Review.

25.

Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate.

Pistoni M, Helsen N, Vanhove J, Boon R, Xu Z, Ordovas L, Verfaillie CM.

PLoS One. 2017 Nov 1;12(11):e0186884. doi: 10.1371/journal.pone.0186884. eCollection 2017.

26.

HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients.

Guo W, Naujock M, Fumagalli L, Vandoorne T, Baatsen P, Boon R, Ordovás L, Patel A, Welters M, Vanwelden T, Geens N, Tricot T, Benoy V, Steyaert J, Lefebvre-Omar C, Boesmans W, Jarpe M, Sterneckert J, Wegner F, Petri S, Bohl D, Vanden Berghe P, Robberecht W, Van Damme P, Verfaillie C, Van Den Bosch L.

Nat Commun. 2017 Oct 11;8(1):861. doi: 10.1038/s41467-017-00911-y.

27.

Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals.

Lanko K, Eggermont K, Patel A, Kaptein S, Delang L, Verfaillie CM, Neyts J.

Antiviral Res. 2017 Sep;145:82-86. doi: 10.1016/j.antiviral.2017.07.010. Epub 2017 Jul 20.

28.

Generation of induced pluripotent stem cells from Chinese hamster embryonic fibroblasts.

Pei H, Fu HY, Hirai H, Cho DS, O'Brien TD, Dutton J, Verfaillie CM, Hu WS.

Stem Cell Res. 2017 May;21:132-136. doi: 10.1016/j.scr.2017.04.010. Epub 2017 Apr 21.

29.

Immunoregulatory effects of multipotent adult progenitor cells in a porcine ex vivo lung perfusion model.

Martens A, Ordies S, Vanaudenaerde BM, Verleden SE, Vos R, Van Raemdonck DE, Verleden GM, Roobrouck VD, Claes S, Schols D, Verbeken E, Verfaillie CM, Neyrinck AP.

Stem Cell Res Ther. 2017 Jul 5;8(1):159. doi: 10.1186/s13287-017-0603-5.

30.

Molecular Imaging of Human Embryonic Stem Cells Stably Expressing Human PET Reporter Genes After Zinc Finger Nuclease-Mediated Genome Editing.

Wolfs E, Holvoet B, Ordovas L, Breuls N, Helsen N, Schönberger M, Raitano S, Struys T, Vanbilloen B, Casteels C, Sampaolesi M, Van Laere K, Lambrichts I, Verfaillie CM, Deroose CM.

J Nucl Med. 2017 Oct;58(10):1659-1665. doi: 10.2967/jnumed.117.189779. Epub 2017 Jun 8.

31.

Multipotent adult progenitor cells improve the hematopoietic function in myelodysplasia.

Roobrouck VD, Wolfs E, Delforge M, Broekaert D, Chakraborty S, Sels K, Vanwelden T, Holvoet B, Lhoest L, Khurana S, Pandey S, Hoornaert C, Ponsaerts P, Struys T, Boeckx N, Vandenberghe P, Deroose CM, Verfaillie CM.

Cytotherapy. 2017 Jun;19(6):744-755. doi: 10.1016/j.jcyt.2017.03.009.

32.

Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells.

Elia I, Broekaert D, Christen S, Boon R, Radaelli E, Orth MF, Verfaillie C, Grünewald TGP, Fendt SM.

Nat Commun. 2017 May 11;8:15267. doi: 10.1038/ncomms15267.

33.

Defining a Leader Role curriculum for radiation oncology: A global Delphi consensus study.

Turner S, Seel M, Trotter T, Giuliani M, Benstead K, Eriksen JG, Poortmans P, Verfaillie C, Westerveld H, Cross S, Chan MK, Shaw T.

Radiother Oncol. 2017 May;123(2):331-336. doi: 10.1016/j.radonc.2017.04.009. Epub 2017 Apr 25.

PMID:
28455152
34.

Hmga2 translocation induced in skin tumorigenesis.

Li Y, Pi XY, Boland K, Lad S, Johnson K, Verfaillie C, Morris RJ.

Oncotarget. 2017 May 2;8(18):30019-30029. doi: 10.18632/oncotarget.16272.

35.

Activin A Modulates CRIPTO-1/HNF4α+ Cells to Guide Cardiac Differentiation from Human Embryonic Stem Cells.

Duelen R, Gilbert G, Patel A, de Schaetzen N, De Waele L, Roderick L, Sipido KR, Verfaillie CM, Buyse GM, Thorrez L, Sampaolesi M.

Stem Cells Int. 2017;2017:4651238. doi: 10.1155/2017/4651238. Epub 2017 Jan 9.

36.

Epithelial organoid cultures from patients with ulcerative colitis and Crohn's disease: a truly long-term model to study the molecular basis for inflammatory bowel disease?

Noben M, Verstockt B, de Bruyn M, Hendriks N, Van Assche G, Vermeire S, Verfaillie C, Ferrante M.

Gut. 2017 Dec;66(12):2193-2195. doi: 10.1136/gutjnl-2016-313667. Epub 2017 Feb 3. No abstract available.

PMID:
28159838
37.

PDGFRα+ Cells in Embryonic Stem Cell Cultures Represent the In Vitro Equivalent of the Pre-implantation Primitive Endoderm Precursors.

Lo Nigro A, de Jaime-Soguero A, Khoueiry R, Cho DS, Ferlazzo GM, Perini I, Abon Escalona V, Aranguren XL, Chuva de Sousa Lopes SM, Koh KP, Conaldi PG, Hu WS, Zwijsen A, Lluis F, Verfaillie CM.

Stem Cell Reports. 2017 Feb 14;8(2):318-333. doi: 10.1016/j.stemcr.2016.12.010. Epub 2017 Jan 12.

38.

Distinct Molecular Signature of Murine Fetal Liver and Adult Hematopoietic Stem Cells Identify Novel Regulators of Hematopoietic Stem Cell Function.

Manesia JK, Franch M, Tabas-Madrid D, Nogales-Cadenas R, Vanwelden T, Van Den Bosch E, Xu Z, Pascual-Montano A, Khurana S, Verfaillie CM.

Stem Cells Dev. 2017 Apr 15;26(8):573-584. doi: 10.1089/scd.2016.0294. Epub 2017 Feb 13.

39.

Perspectives on medical education in radiation oncology and the role of the ESTRO School.

Eriksen JG, Leech M, Benstead K, Verfaillie C.

Clin Transl Radiat Oncol. 2016 Dec 10;1:15-18. doi: 10.1016/j.ctro.2016.10.001. eCollection 2016 Dec.

40.

Rapid and Efficient Generation of Recombinant Human Pluripotent Stem Cells by Recombinase-mediated Cassette Exchange in the AAVS1 Locus.

Ordovás L, Boon R, Pistoni M, Chen Y, Sambathkumar R, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Raitano S, Verfaillie CM.

J Vis Exp. 2016 Nov 20;(117). doi: 10.3791/54718.

41.

Outside-in integrin signalling regulates haematopoietic stem cell function via Periostin-Itgav axis.

Khurana S, Schouteden S, Manesia JK, Santamaria-Martínez A, Huelsken J, Lacy-Hulbert A, Verfaillie CM.

Nat Commun. 2016 Dec 1;7:13500. doi: 10.1038/ncomms13500.

42.

Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors.

Lorendeau D, Rinaldi G, Boon R, Spincemaille P, Metzger K, Jäger C, Christen S, Dong X, Kuenen S, Voordeckers K, Verstreken P, Cassiman D, Vermeersch P, Verfaillie C, Hiller K, Fendt SM.

Metab Eng. 2017 Sep;43(Pt B):187-197. doi: 10.1016/j.ymben.2016.11.005. Epub 2016 Nov 12.

PMID:
27847310
43.

De novo design of a biologically active amyloid.

Gallardo R, Ramakers M, De Smet F, Claes F, Khodaparast L, Khodaparast L, Couceiro JR, Langenberg T, Siemons M, Nyström S, Young LJ, Laine RF, Young L, Radaelli E, Benilova I, Kumar M, Staes A, Desager M, Beerens M, Vandervoort P, Luttun A, Gevaert K, Bormans G, Dewerchin M, Van Eldere J, Carmeliet P, Vande Velde G, Verfaillie C, Kaminski CF, De Strooper B, Hammarström P, Nilsson KP, Serpell L, Schymkowitz J, Rousseau F.

Science. 2016 Nov 11;354(6313). pii: aah4949.

44.

Vascular Diseases and Metabolic Disorders.

Feng YM, Verfaillie C, Yu H.

Stem Cells Int. 2016;2016:5810358. Epub 2016 Oct 19. No abstract available.

45.

Cell Expansion During Directed Differentiation of Stem Cells Toward the Hepatic Lineage.

Raju R, Chau D, Cho DS, Park Y, Verfaillie CM, Hu WS.

Stem Cells Dev. 2017 Feb 15;26(4):274-284. doi: 10.1089/scd.2016.0119. Epub 2016 Nov 1.

46.

H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro.

Vanhove J, Pistoni M, Welters M, Eggermont K, Vanslembrouck V, Helsen N, Boon R, Najimi M, Sokal E, Collas P, Voncken JW, Verfaillie CM.

Stem Cell Reports. 2016 Aug 9;7(2):192-206. doi: 10.1016/j.stemcr.2016.06.013. Epub 2016 Jul 28.

47.

Clinical-Grade Human Multipotent Adult Progenitor Cells Block CD8+ Cytotoxic T Lymphocytes.

Plessers J, Dekimpe E, Van Woensel M, Roobrouck VD, Bullens DM, Pinxteren J, Verfaillie CM, Van Gool SW.

Stem Cells Transl Med. 2016 Dec;5(12):1607-1619. Epub 2016 Jul 27.

48.

Epigenetic Induction of Definitive and Pancreatic Endoderm Cell Fate in Human Fibroblasts.

Sambathkumar R, Kalo E, Van Rossom R, Faas MM, de Vos P, Verfaillie CM.

Stem Cells Int. 2016;2016:7654321. doi: 10.1155/2016/7654321. Epub 2016 Jun 15.

49.

Allele-specific DNA methylation reinforces PEAR1 enhancer activity.

Izzi B, Pistoni M, Cludts K, Akkor P, Lambrechts D, Verfaillie C, Verhamme P, Freson K, Hoylaerts MF.

Blood. 2016 Aug 18;128(7):1003-12. doi: 10.1182/blood-2015-11-682153. Epub 2016 Jun 16.

50.

Pancreatic differentiation of Pdx1-GFP reporter mouse induced pluripotent stem cells.

Porciuncula A, Kumar A, Rodriguez S, Atari M, Araña M, Martin F, Soria B, Prosper F, Verfaillie C, Barajas M.

Differentiation. 2016 Dec;92(5):249-256. doi: 10.1016/j.diff.2016.04.005. Epub 2016 May 12.

PMID:
27181524

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