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Items: 4


Repurposed Biguanide Drugs in Glioblastoma Exert Antiproliferative Effects via the Inhibition of Intracellular Chloride Channel 1 Activity.

Barbieri F, Verduci I, Carlini V, Zona G, Pagano A, Mazzanti M, Florio T.

Front Oncol. 2019 Mar 13;9:135. doi: 10.3389/fonc.2019.00135. eCollection 2019. Review.


Antiestrogen- and tamoxifen-induced effects on calcium-activated chloride currents in epithelial cells carrying the ∆F508-CFTR point mutation.

Imberti R, Garavaglia ML, Verduci I, Cannavale G, Balduzzi G, Papetti S, Mazzanti M.

Respir Res. 2018 Oct 5;19(1):198. doi: 10.1186/s12931-018-0901-1.


Inhibition of Chloride Intracellular Channel 1 (CLIC1) as Biguanide Class-Effect to Impair Human Glioblastoma Stem Cell Viability.

Barbieri F, Würth R, Pattarozzi A, Verduci I, Mazzola C, Cattaneo MG, Tonelli M, Solari A, Bajetto A, Daga A, Vicentini LM, Mazzanti M, Florio T.

Front Pharmacol. 2018 Aug 21;9:899. doi: 10.3389/fphar.2018.00899. eCollection 2018.


Mutual Influence of ROS, pH, and CLIC1 Membrane Protein in the Regulation of G1-S Phase Progression in Human Glioblastoma Stem Cells.

Peretti M, Raciti FM, Carlini V, Verduci I, Sertic S, Barozzi S, Garré M, Pattarozzi A, Daga A, Barbieri F, Costa A, Florio T, Mazzanti M.

Mol Cancer Ther. 2018 Nov;17(11):2451-2461. doi: 10.1158/1535-7163.MCT-17-1223. Epub 2018 Aug 22.


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