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Items: 1 to 50 of 143

1.

Real-world Gluten Exposure in Patients With Celiac Disease on Gluten-Free Diets, Determined From Gliadin Immunogenic Peptides in Urine and Fecal Samples.

Stefanolo JP, Tálamo M, Dodds S, Temprano MP, Costa AF, Moreno ML, Pinto-Sánchez MI, Smecuol E, Vázquez H, Gonzalez A, Niveloni SI, Mauriño E, Verdu EF, Bai JC.

Clin Gastroenterol Hepatol. 2020 Mar 23. pii: S1542-3565(20)30350-5. doi: 10.1016/j.cgh.2020.03.038. [Epub ahead of print]

PMID:
32217152
2.

Microbial Regulation of Enteric Eosinophils and Its Impact on Tissue Remodeling and Th2 Immunity.

Jiménez-Saiz R, Anipindi VC, Galipeau H, Ellenbogen Y, Chaudhary R, Koenig JF, Gordon ME, Walker TD, Mandur TS, Abed S, Humbles A, Chu DK, Erjefält J, Ask K, Verdú EF, Jordana M.

Front Immunol. 2020 Feb 13;11:155. doi: 10.3389/fimmu.2020.00155. eCollection 2020.

3.

Effects of Antibiotic Pretreatment of an Ulcerative Colitis-Derived Fecal Microbial Community on the Integration of Therapeutic Bacteria In Vitro.

Oliphant K, Cochrane K, Schroeter K, Daigneault MC, Yen S, Verdu EF, Allen-Vercoe E.

mSystems. 2020 Jan 28;5(1). pii: e00404-19. doi: 10.1128/mSystems.00404-19.

4.

The enemy within the gut: bacterial pathogens in celiac autoimmunity.

Verdu EF, Schuppan D.

Nat Struct Mol Biol. 2020 Jan;27(1):5-7. doi: 10.1038/s41594-019-0360-5. No abstract available.

PMID:
31873302
5.

A Novel Mouse Model of Enteric Vibrio parahaemolyticus Infection Reveals that the Type III Secretion System 2 Effector VopC Plays a Key Role in Tissue Invasion and Gastroenteritis.

Yang H, de Souza Santos M, Lee J, Law HT, Chimalapati S, Verdu EF, Orth K, Vallance BA.

mBio. 2019 Dec 17;10(6). pii: e02608-19. doi: 10.1128/mBio.02608-19.

6.

Active thrombin produced by the intestinal epithelium controls mucosal biofilms.

Motta JP, Denadai-Souza A, Sagnat D, Guiraud L, Edir A, Bonnart C, Sebbag M, Rousset P, Lapeyre A, Seguy C, Mathurine-Thomas N, Galipeau HJ, Bonnet D, Alric L, Buret AG, Wallace JL, Dufour A, Verdu EF, Hollenberg MD, Oswald E, Serino M, Deraison C, Vergnolle N.

Nat Commun. 2019 Jul 19;10(1):3224. doi: 10.1038/s41467-019-11140-w.

7.

The impact of dietary fermentable carbohydrates on a postinflammatory model of irritable bowel syndrome.

Tuck CJ, Caminero A, Jiménez Vargas NN, Soltys CL, Jaramillo Polanco JO, Lopez Lopez CD, Constante M, Lourenssen SR, Verdu EF, Muir JG, Lomax AE, Reed DE, Vanner SJ.

Neurogastroenterol Motil. 2019 Oct;31(10):e13675. doi: 10.1111/nmo.13675. Epub 2019 Jul 9.

PMID:
31290223
8.

Metabolism of wheat proteins by intestinal microbes: Implications for wheat related disorders.

Caminero A, Verdu EF.

Gastroenterol Hepatol. 2019 Aug - Sep;42(7):449-457. doi: 10.1016/j.gastrohep.2019.04.001. Epub 2019 Jun 28. Review. English, Spanish.

PMID:
31262542
9.

Celiac disease: should we care about microbes?

Caminero A, Verdu EF.

Am J Physiol Gastrointest Liver Physiol. 2019 Aug 1;317(2):G161-G170. doi: 10.1152/ajpgi.00099.2019. Epub 2019 Jun 12. Review.

PMID:
31188640
10.

Evolving Paradigms in the Diagnosis of Adult Patients With Celiac Disease.

Bai JC, Verdú EF.

Am J Gastroenterol. 2019 Jun;114(6):854-857. doi: 10.14309/ajg.0000000000000279. Review. No abstract available.

PMID:
31136311
11.

Investigation of the Gut Microbiome in Patients with Schizophrenia and Clozapine-Induced Weight Gain: Protocol and Clinical Characteristics of First Patient Cohorts.

Gorbovskaya I, Kanji S, Liu JCW, MacKenzie NE, Agarwal SM, Marshe VS, Sriretnakumar V, Verdu EF, Bercik P, De Palma G, Hahn MK, Müller DJ.

Neuropsychobiology. 2020;79(1):5-12. doi: 10.1159/000494696. Epub 2019 Mar 29.

PMID:
30928978
12.

Gluten immunogenic peptide excretion detects dietary transgressions in treated celiac disease patients.

Costa AF, Sugai E, Temprano MP, Niveloni SI, Vázquez H, Moreno ML, Domínguez-Flores MR, Muñoz-Suano A, Smecuol E, Stefanolo JP, González AF, Cebolla-Ramirez A, Mauriño E, Verdú EF, Bai JC.

World J Gastroenterol. 2019 Mar 21;25(11):1409-1420. doi: 10.3748/wjg.v25.i11.1409.

13.

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2.

Caminero A, McCarville JL, Galipeau HJ, Deraison C, Bernier SP, Constante M, Rolland C, Meisel M, Murray JA, Yu XB, Alaedini A, Coombes BK, Bercik P, Southward CM, Ruf W, Jabri B, Chirdo FG, Casqueiro J, Surette MG, Vergnolle N, Verdu EF.

Nat Commun. 2019 Mar 13;10(1):1198. doi: 10.1038/s41467-019-09037-9.

14.

Non-celiac gluten or wheat sensitivity: It's complicated!

Pinto-Sanchez MI, Verdu EF.

Neurogastroenterol Motil. 2018 Aug;30(8):e13392. doi: 10.1111/nmo.13392. Review.

PMID:
30854780
15.

Lactobacilli Degrade Wheat Amylase Trypsin Inhibitors to Reduce Intestinal Dysfunction Induced by Immunogenic Wheat Proteins.

Caminero A, McCarville JL, Zevallos VF, Pigrau M, Yu XB, Jury J, Galipeau HJ, Clarizio AV, Casqueiro J, Murray JA, Collins SM, Alaedini A, Bercik P, Schuppan D, Verdu EF.

Gastroenterology. 2019 Jun;156(8):2266-2280. doi: 10.1053/j.gastro.2019.02.028. Epub 2019 Feb 22.

PMID:
30802444
16.

Coeliac disease.

Lindfors K, Ciacci C, Kurppa K, Lundin KEA, Makharia GK, Mearin ML, Murray JA, Verdu EF, Kaukinen K.

Nat Rev Dis Primers. 2019 Jan 10;5(1):3. doi: 10.1038/s41572-018-0054-z. Review.

PMID:
30631077
17.

Intestinal organoids: A new paradigm for engineering intestinal epithelium in vitro.

Rahmani S, Breyner NM, Su HM, Verdu EF, Didar TF.

Biomaterials. 2019 Feb;194:195-214. doi: 10.1016/j.biomaterials.2018.12.006. Epub 2018 Dec 10. Review.

PMID:
30612006
18.

Small-Molecule Allosteric Triggers of Clostridium difficile Toxin B Auto-proteolysis as a Therapeutic Strategy.

Ivarsson ME, Durantie E, Huberli C, Huwiler S, Hegde C, Friedman J, Altamura F, Lu J, Verdu EF, Bercik P, Logan SM, Chen W, Leroux JC, Castagner B.

Cell Chem Biol. 2019 Jan 17;26(1):17-26.e13. doi: 10.1016/j.chembiol.2018.10.002. Epub 2018 Oct 25.

19.

Commensal microbiota induces colonic barrier structure and functions that contribute to homeostasis.

Hayes CL, Dong J, Galipeau HJ, Jury J, McCarville J, Huang X, Wang XY, Naidoo A, Anbazhagan AN, Libertucci J, Sheridan C, Dudeja PK, Bowdish DME, Surette MG, Verdu EF.

Sci Rep. 2018 Sep 21;8(1):14184. doi: 10.1038/s41598-018-32366-6.

20.

Mechanisms by which gut microorganisms influence food sensitivities.

Caminero A, Meisel M, Jabri B, Verdu EF.

Nat Rev Gastroenterol Hepatol. 2019 Jan;16(1):7-18. doi: 10.1038/s41575-018-0064-z. Review.

21.

Common ground: shared risk factors for type 1 diabetes and celiac disease.

Verdu EF, Danska JS.

Nat Immunol. 2018 Jul;19(7):685-695. doi: 10.1038/s41590-018-0130-2. Epub 2018 Jun 20. Review.

PMID:
29925984
22.

Inflammation-related differences in mucosa-associated microbiota and intestinal barrier function in colonic Crohn's disease.

Libertucci J, Dutta U, Kaur S, Jury J, Rossi L, Fontes ME, Shajib MS, Khan WI, Surette MG, Verdu EF, Armstrong D.

Am J Physiol Gastrointest Liver Physiol. 2018 Sep 1;315(3):G420-G431. doi: 10.1152/ajpgi.00411.2017. Epub 2018 May 31.

23.

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

Meisel M, Hinterleitner R, Pacis A, Chen L, Earley ZM, Mayassi T, Pierre JF, Ernest JD, Galipeau HJ, Thuille N, Bouziat R, Buscarlet M, Ringus DL, Wang Y, Li Y, Dinh V, Kim SM, McDonald BD, Zurenski MA, Musch MW, Furtado GC, Lira SA, Baier G, Chang EB, Eren AM, Weber CR, Busque L, Godley LA, Verdú EF, Barreiro LB, Jabri B.

Nature. 2018 May;557(7706):580-584. doi: 10.1038/s41586-018-0125-z. Epub 2018 May 16.

24.

Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction.

Thevaranjan N, Puchta A, Schulz C, Naidoo A, Szamosi JC, Verschoor CP, Loukov D, Schenck LP, Jury J, Foley KP, Schertzer JD, Larché MJ, Davidson DJ, Verdú EF, Surette MG, Bowdish DME.

Cell Host Microbe. 2018 Apr 11;23(4):570. doi: 10.1016/j.chom.2018.03.006. No abstract available.

25.

High salt diet exacerbates colitis in mice by decreasing Lactobacillus levels and butyrate production.

Miranda PM, De Palma G, Serkis V, Lu J, Louis-Auguste MP, McCarville JL, Verdu EF, Collins SM, Bercik P.

Microbiome. 2018 Mar 22;6(1):57. doi: 10.1186/s40168-018-0433-4.

26.

A Commensal Bifidobacterium longum Strain Prevents Gluten-Related Immunopathology in Mice through Expression of a Serine Protease Inhibitor.

McCarville JL, Dong J, Caminero A, Bermudez-Brito M, Jury J, Murray JA, Duboux S, Steinmann M, Delley M, Tangyu M, Langella P, Mercenier A, Bergonzelli G, Verdu EF.

Appl Environ Microbiol. 2017 Sep 15;83(19). pii: e01323-17. doi: 10.1128/AEM.01323-17. Print 2017 Oct 1.

27.

Safety of Adding Oats to a Gluten-Free Diet for Patients With Celiac Disease: Systematic Review and Meta-analysis of Clinical and Observational Studies.

Pinto-Sánchez MI, Causada-Calo N, Bercik P, Ford AC, Murray JA, Armstrong D, Semrad C, Kupfer SS, Alaedini A, Moayyedi P, Leffler DA, Verdú EF, Green P.

Gastroenterology. 2017 Aug;153(2):395-409.e3. doi: 10.1053/j.gastro.2017.04.009. Epub 2017 Apr 18. Review.

28.

Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction.

Thevaranjan N, Puchta A, Schulz C, Naidoo A, Szamosi JC, Verschoor CP, Loukov D, Schenck LP, Jury J, Foley KP, Schertzer JD, Larché MJ, Davidson DJ, Verdú EF, Surette MG, Bowdish DME.

Cell Host Microbe. 2017 Apr 12;21(4):455-466.e4. doi: 10.1016/j.chom.2017.03.002. Erratum in: Cell Host Microbe. 2018 Apr 11;23 (4):570.

29.

How infection can incite sensitivity to food.

Verdu EF, Caminero A.

Science. 2017 Apr 7;356(6333):29-30. doi: 10.1126/science.aan1500. No abstract available.

PMID:
28385972
30.

The CD That Pays Dividends: More Than 15 Years of Deamidated Gliadin Peptide Antibodies.

Bai JC, Verdú EF.

Dig Dis Sci. 2017 May;62(5):1110-1112. doi: 10.1007/s10620-017-4528-8. No abstract available.

PMID:
28315033
31.

Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice.

De Palma G, Lynch MD, Lu J, Dang VT, Deng Y, Jury J, Umeh G, Miranda PM, Pigrau Pastor M, Sidani S, Pinto-Sanchez MI, Philip V, McLean PG, Hagelsieb MG, Surette MG, Bergonzelli GE, Verdu EF, Britz-McKibbin P, Neufeld JD, Collins SM, Bercik P.

Sci Transl Med. 2017 Mar 1;9(379). pii: eaaf6397. doi: 10.1126/scitranslmed.aaf6397.

PMID:
28251905
32.

Bifidobacterium infantis NLS Super Strain Reduces the Expression of α-Defensin-5, a Marker of Innate Immunity, in the Mucosa of Active Celiac Disease Patients.

Pinto-Sánchez MI, Smecuol EC, Temprano MP, Sugai E, González A, Moreno ML, Huang X, Bercik P, Cabanne A, Vázquez H, Niveloni S, Mazure R, Mauriño E, Verdú EF, Bai JC.

J Clin Gastroenterol. 2017 Oct;51(9):814-817. doi: 10.1097/MCG.0000000000000687.

PMID:
27636409
33.

Non-coeliac gluten sensitivity: are we closer to separating the wheat from the chaff?

Pinto-Sánchez MI, Verdú EF.

Gut. 2016 Dec;65(12):1921-1922. doi: 10.1136/gutjnl-2016-312471. Epub 2016 Aug 16. No abstract available.

PMID:
27531827
34.

Addressing proteolytic efficiency in enzymatic degradation therapy for celiac disease.

Rey M, Yang M, Lee L, Zhang Y, Sheff JG, Sensen CW, Mrazek H, Halada P, Man P, McCarville JL, Verdu EF, Schriemer DC.

Sci Rep. 2016 Aug 2;6:30980. doi: 10.1038/srep30980.

35.

Altered Esophageal Mucosal Structure in Patients with Celiac Disease.

Pinto-Sánchez MI, Nachman FD, Fuxman C, Iantorno G, Hwang HJ, Ditaranto A, Costa F, Longarini G, Wang XY, Huang X, Vázquez H, Moreno ML, Niveloni S, Bercik P, Smecuol E, Mazure R, Bilder C, Mauriño EC, Verdu EF, Bai JC.

Can J Gastroenterol Hepatol. 2016;2016:1980686. doi: 10.1155/2016/1980686. Epub 2016 Feb 29.

36.

Dietary Triggers in Irritable Bowel Syndrome: Is There a Role for Gluten?

Volta U, Pinto-Sanchez MI, Boschetti E, Caio G, De Giorgio R, Verdu EF.

J Neurogastroenterol Motil. 2016 Oct 30;22(4):547-557. doi: 10.5056/jnm16069. Review.

37.

Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity.

Caminero A, Galipeau HJ, McCarville JL, Johnston CW, Bernier SP, Russell AK, Jury J, Herran AR, Casqueiro J, Tye-Din JA, Surette MG, Magarvey NA, Schuppan D, Verdu EF.

Gastroenterology. 2016 Oct;151(4):670-83. doi: 10.1053/j.gastro.2016.06.041. Epub 2016 Jun 30.

PMID:
27373514
38.

Novel perspectives on therapeutic modulation of the gut microbiota.

McCarville JL, Caminero A, Verdu EF.

Therap Adv Gastroenterol. 2016 Jul;9(4):580-93. doi: 10.1177/1756283X16637819. Epub 2016 Apr 4. Review.

39.

The complex task of measuring intestinal permeability in basic and clinical science.

Galipeau HJ, Verdu EF.

Neurogastroenterol Motil. 2016 Jul;28(7):957-65. doi: 10.1111/nmo.12871. Review.

PMID:
27339216
40.

Bifidobacterium animalis ssp. lactis CNCM-I2494 Restores Gut Barrier Permeability in Chronically Low-Grade Inflamed Mice.

Martín R, Laval L, Chain F, Miquel S, Natividad J, Cherbuy C, Sokol H, Verdu EF, van Hylckama Vlieg J, Bermudez-Humaran LG, Smokvina T, Langella P.

Front Microbiol. 2016 May 6;7:608. doi: 10.3389/fmicb.2016.00608. eCollection 2016.

41.

Mechanisms of innate immune activation by gluten peptide p31-43 in mice.

Araya RE, Gomez Castro MF, Carasi P, McCarville JL, Jury J, Mowat AM, Verdu EF, Chirdo FG.

Am J Physiol Gastrointest Liver Physiol. 2016 Jul 1;311(1):G40-9. doi: 10.1152/ajpgi.00435.2015. Epub 2016 May 5.

42.

Fundamentals of Neurogastroenterology: Basic Science.

Vanner S, Greenwood-Van Meerveld B, Mawe G, Shea-Donohue T, Verdu EF, Wood J, Grundy D.

Gastroenterology. 2016 Feb 18. pii: S0016-5085(16)00184-0. doi: 10.1053/j.gastro.2016.02.018. [Epub ahead of print]

43.

SHP-2 Phosphatase Prevents Colonic Inflammation by Controlling Secretory Cell Differentiation and Maintaining Host-Microbiota Homeostasis.

Coulombe G, Langlois A, De Palma G, Langlois MJ, McCarville JL, Gagné-Sanfaçon J, Perreault N, Feng GS, Bercik P, Boudreau F, Verdu EF, Rivard N.

J Cell Physiol. 2016 Nov;231(11):2529-40. doi: 10.1002/jcp.25407. Epub 2016 May 8.

44.

Optimization of metabolomics of defined in vitro gut microbial ecosystems.

Wissenbach DK, Oliphant K, Rolle-Kampczyk U, Yen S, Höke H, Baumann S, Haange SB, Verdu EF, Allen-Vercoe E, von Bergen M.

Int J Med Microbiol. 2016 Aug;306(5):280-289. doi: 10.1016/j.ijmm.2016.03.007. Epub 2016 Mar 16. Review.

PMID:
27020116
45.

Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways.

Kirkby NS, Chan MV, Zaiss AK, Garcia-Vaz E, Jiao J, Berglund LM, Verdu EF, Ahmetaj-Shala B, Wallace JL, Herschman HR, Gomez MF, Mitchell JA.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):434-9. doi: 10.1073/pnas.1517642113. Epub 2015 Dec 28.

46.

Gluten Introduction to Infant Feeding and Risk of Celiac Disease: Systematic Review and Meta-Analysis.

Pinto-Sánchez MI, Verdu EF, Liu E, Bercik P, Green PH, Murray JA, Guandalini S, Moayyedi P.

J Pediatr. 2016 Jan;168:132-43.e3. doi: 10.1016/j.jpeds.2015.09.032. Epub 2015 Oct 21. Review. Erratum in: J Pediatr. 2016 Feb;169:331.

PMID:
26500108
47.

Should ESPGHAN guidelines for serologic diagnosis of celiac disease be used in adults? A prospective analysis in an adult patient cohort with high pretest probability.

Sugai E, Hwang HJ, Vázquez H, Moreno ML, Costa F, Longarini G, Pinto-Sánchez MI, Niveloni S, Smecuol E, Mazure RM, Verdu EF, Mauriño E, Bai JC.

Am J Gastroenterol. 2015 Oct;110(10):1504-5. doi: 10.1038/ajg.2015.242. No abstract available.

PMID:
26465908
48.

Intestinal microbiota modulates gluten-induced immunopathology in humanized mice.

Galipeau HJ, McCarville JL, Huebener S, Litwin O, Meisel M, Jabri B, Sanz Y, Murray JA, Jordana M, Alaedini A, Chirdo FG, Verdu EF.

Am J Pathol. 2015 Nov;185(11):2969-82. doi: 10.1016/j.ajpath.2015.07.018. Epub 2015 Oct 9.

49.

Pharmacological approaches in celiac disease.

McCarville JL, Caminero A, Verdu EF.

Curr Opin Pharmacol. 2015 Dec;25:7-12. doi: 10.1016/j.coph.2015.09.002. Epub 2015 Sep 27. Review.

PMID:
26414923
50.

Gluten Introduction, Breastfeeding, and Celiac Disease: Back to the Drawing Board.

Lebwohl B, Murray JA, Verdú EF, Crowe SE, Dennis M, Fasano A, Green PH, Guandalini S, Khosla C.

Am J Gastroenterol. 2016 Jan;111(1):12-4. doi: 10.1038/ajg.2015.219. Epub 2015 Aug 11.

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