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Items: 7

1.

ApoA-I mimetic peptides promote pre-β HDL formation in vivo causing remodeling of HDL and triglyceride accumulation at higher dose.

Carballo-Jane E, Chen Z, O'Neill E, Wang J, Burton C, Chang CH, Chen X, Eveland S, Frantz-Wattley B, Gagen K, Hubbard B, Ichetovkin M, Luell S, Meurer R, Song X, Strack A, Langella A, Cianetti S, Rech F, Capitò E, Bufali S, Veneziano M, Verdirame M, Bonelli F, Monteagudo E, Pessi A, Ingenito R, Bianchi E.

Bioorg Med Chem. 2010 Dec 15;18(24):8669-78. doi: 10.1016/j.bmc.2010.09.074. Epub 2010 Nov 4.

PMID:
21115285
2.

Turbulent flow chromatography TFC-tandem mass spectrometry supporting in vitro/vivo studies of NCEs in high throughput fashion.

Verdirame M, Veneziano M, Alfieri A, Di Marco A, Monteagudo E, Bonelli F.

J Pharm Biomed Anal. 2010 Mar 11;51(4):834-41. doi: 10.1016/j.jpba.2009.10.005. Epub 2009 Oct 12.

PMID:
19896318
3.

An oral TLR7 agonist is a potent adjuvant of DNA vaccination in transgenic mouse tumor models.

Dharmapuri S, Aurisicchio L, Neuner P, Verdirame M, Ciliberto G, La Monica N.

Cancer Gene Ther. 2009 May;16(5):462-72. doi: 10.1038/cgt.2008.91. Epub 2008 Nov 7.

PMID:
18989354
4.

A novel series of potent and selective ketone histone deacetylase inhibitors with antitumor activity in vivo.

Jones P, Altamura S, De Francesco R, Paz OG, Kinzel O, Mesiti G, Monteagudo E, Pescatore G, Rowley M, Verdirame M, Steinkühler C.

J Med Chem. 2008 Apr 24;51(8):2350-3. doi: 10.1021/jm800079s. Epub 2008 Mar 28.

PMID:
18370373
5.

Discovery and synthesis of HIV integrase inhibitors: development of potent and orally bioavailable N-methyl pyrimidones.

Gardelli C, Nizi E, Muraglia E, Crescenzi B, Ferrara M, Orvieto F, Pace P, Pescatore G, Poma M, Ferreira Mdel R, Scarpelli R, Homnick CF, Ikemoto N, Alfieri A, Verdirame M, Bonelli F, Paz OG, Taliani M, Monteagudo E, Pesci S, Laufer R, Felock P, Stillmock KA, Hazuda D, Rowley M, Summa V.

J Med Chem. 2007 Oct 4;50(20):4953-75. Epub 2007 Sep 8.

PMID:
17824681
6.

Development and validation of a high-throughput radiometric CYP3A4/5 inhibition assay using tritiated testosterone.

Di Marco A, Marcucci I, Verdirame M, Pérez J, Sanchez M, Peláez F, Chaudhary A, Laufer R.

Drug Metab Dispos. 2005 Mar;33(3):349-58. Epub 2004 Dec 17.

7.

SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease.

Malancona S, Colarusso S, Ontoria JM, Marchetti A, Poma M, Stansfield I, Laufer R, Di Marco A, Taliani M, Verdirame M, Gonzalez-Paz O, Matassa VG, Narjes F.

Bioorg Med Chem Lett. 2004 Sep 6;14(17):4575-9.

PMID:
15357995

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