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Items: 45

1.

Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies.

Bowers PM, Verdino P, Wang Z, da Silva Correia J, Chhoa M, Macondray G, Do M, Neben TY, Horlick RA, Stanfield RL, Wilson IA, King DJ.

J Biol Chem. 2014 Nov 28;289(48):33557-67. doi: 10.1074/jbc.M114.607176. Epub 2014 Oct 15.

2.

Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids.

Jiménez-Dalmaroni MJ, Radcliffe CM, Harvey DJ, Wormald MR, Verdino P, Ainge GD, Larsen DS, Painter GF, Ulevitch R, Beutler B, Rudd PM, Dwek RA, Wilson IA.

Innate Immun. 2015 Feb;21(2):175-93. doi: 10.1177/1753425914524077. Epub 2014 Mar 3.

3.

Mammalian cell display for the discovery and optimization of antibody therapeutics.

Bowers PM, Horlick RA, Kehry MR, Neben TY, Tomlinson GL, Altobell L, Zhang X, Macomber JL, Krapf IP, Wu BF, McConnell AD, Chau B, Berkebile AD, Hare E, Verdino P, King DJ.

Methods. 2014 Jan 1;65(1):44-56. doi: 10.1016/j.ymeth.2013.06.010. Epub 2013 Jun 20.

PMID:
23792919
4.

Simultaneous surface display and secretion of proteins from mammalian cells facilitate efficient in vitro selection and maturation of antibodies.

Horlick RA, Macomber JL, Bowers PM, Neben TY, Tomlinson GL, Krapf IP, Dalton JL, Verdino P, King DJ.

J Biol Chem. 2013 Jul 5;288(27):19861-9. doi: 10.1074/jbc.M113.452482. Epub 2013 May 20.

5.

Humanization of antibodies using heavy chain complementarity-determining region 3 grafting coupled with in vitro somatic hypermutation.

Bowers PM, Neben TY, Tomlinson GL, Dalton JL, Altobell L, Zhang X, Macomber JL, Wu BF, Toobian RM, McConnell AD, Verdino P, Chau B, Horlick RA, King DJ.

J Biol Chem. 2013 Mar 15;288(11):7688-96. doi: 10.1074/jbc.M112.445502. Epub 2013 Jan 25.

6.

The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal γδ T cell function.

Witherden DA, Watanabe M, Garijo O, Rieder SE, Sarkisyan G, Cronin SJ, Verdino P, Wilson IA, Kumanogoh A, Kikutani H, Teyton L, Fischer WH, Havran WL.

Immunity. 2012 Aug 24;37(2):314-25. doi: 10.1016/j.immuni.2012.05.026. Epub 2012 Aug 16.

7.

cDNA sequence and Fab crystal structure of HL4E10, a hamster IgG lambda light chain antibody stimulatory for γδ T cells.

Verdino P, Witherden DA, Podshivalova K, Rieder SE, Havran WL, Wilson IA.

PLoS One. 2011;6(5):e19828. doi: 10.1371/journal.pone.0019828. Epub 2011 May 24.

8.

JAML and CAR: two more players in T-cell activation.

Verdino P, Wilson IA.

Cell Cycle. 2011 May 1;10(9):1341-2. doi: 10.4161/cc.10.9.15294. Epub 2011 May 1. No abstract available.

PMID:
21566459
9.

Molecular insights into γδ T cell costimulation by an anti-JAML antibody.

Verdino P, Witherden DA, Ferguson MS, Corper AL, Schiefner A, Havran WL, Wilson IA.

Structure. 2011 Jan 12;19(1):80-9. doi: 10.1016/j.str.2010.10.007.

10.

The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K.

Verdino P, Witherden DA, Havran WL, Wilson IA.

Science. 2010 Sep 3;329(5996):1210-4. doi: 10.1126/science.1187996.

11.

The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation.

Witherden DA, Verdino P, Rieder SE, Garijo O, Mills RE, Teyton L, Fischer WH, Wilson IA, Havran WL.

Science. 2010 Sep 3;329(5996):1205-10. doi: 10.1126/science.1192698.

12.

Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.

Jimenez-Dalmaroni MJ, Xiao N, Corper AL, Verdino P, Ainge GD, Larsen DS, Painter GF, Rudd PM, Dwek RA, Hoebe K, Beutler B, Wilson IA.

PLoS One. 2009 Oct 22;4(10):e7411. doi: 10.1371/journal.pone.0007411.

13.

Disruption of allergenic activity of the major grass pollen allergen Phl p 2 by reassembly as a mosaic protein.

Mothes-Luksch N, Stumvoll S, Linhart B, Focke M, Krauth MT, Hauswirth A, Valent P, Verdino P, Pavkov T, Keller W, Grote M, Valenta R.

J Immunol. 2008 Oct 1;181(7):4864-73.

14.

Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.

Verdino P, Aldag C, Hilvert D, Wilson IA.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11725-30. doi: 10.1073/pnas.0801783105. Epub 2008 Aug 8.

15.

Three-dimensional structure of the cross-reactive pollen allergen Che a 3: visualizing cross-reactivity on the molecular surfaces of weed, grass, and tree pollen allergens.

Verdino P, Barderas R, Villalba M, Westritschnig K, Valenta R, Rodriguez R, Keller W.

J Immunol. 2008 Feb 15;180(4):2313-21.

16.

Genetic engineering of the major timothy grass pollen allergen, Phl p 6, to reduce allergenic activity and preserve immunogenicity.

Vrtala S, Focke M, Kopec J, Verdino P, Hartl A, Sperr WR, Fedorov AA, Ball T, Almo S, Valent P, Thalhamer J, Keller W, Valenta R.

J Immunol. 2007 Aug 1;179(3):1730-9.

17.

A recombinant hypoallergenic parvalbumin mutant for immunotherapy of IgE-mediated fish allergy.

Swoboda I, Bugajska-Schretter A, Linhart B, Verdino P, Keller W, Schulmeister U, Sperr WR, Valent P, Peltre G, Quirce S, Douladiris N, Papadopoulos NG, Valenta R, Spitzauer S.

J Immunol. 2007 May 15;178(10):6290-6.

18.

Molecular determinants of allergen-induced effector cell degranulation.

Gieras A, Focke-Tejkl M, Ball T, Verdino P, Hartl A, Thalhamer J, Valenta R.

J Allergy Clin Immunol. 2007 Feb;119(2):384-90. Epub 2006 Nov 7.

PMID:
17291855
19.

Maturation of shark single-domain (IgNAR) antibodies: evidence for induced-fit binding.

Stanfield RL, Dooley H, Verdino P, Flajnik MF, Wilson IA.

J Mol Biol. 2007 Mar 23;367(2):358-72. Epub 2006 Dec 22.

PMID:
17258766
20.

Spatial clustering of the IgE epitopes on the major timothy grass pollen allergen Phl p 1: importance for allergenic activity.

Flicker S, Steinberger P, Ball T, Krauth MT, Verdino P, Valent P, Almo S, Valenta R.

J Allergy Clin Immunol. 2006 Jun;117(6):1336-43. Epub 2006 Apr 27.

PMID:
16750995
21.

Structural characterization of pollen allergens.

Verdino P.

Clin Rev Allergy Immunol. 2006 Apr;30(2):73-95. Review.

PMID:
16645221
22.

Bacterial fermentation of recombinant major wasp allergen Antigen 5 using oxygen limiting growth conditions improves yield and quality of inclusion bodies.

Kischnick S, Weber B, Verdino P, Keller W, Sanders EA, Anspach FB, Fiebig H, Cromwell O, Suck R.

Protein Expr Purif. 2006 Jun;47(2):621-8. Epub 2006 Feb 8.

PMID:
16495080
23.

Dimerization of the major birch pollen allergen Bet v 1 is important for its in vivo IgE-cross-linking potential in mice.

Schöll I, Kalkura N, Shedziankova Y, Bergmann A, Verdino P, Knittelfelder R, Kopp T, Hantusch B, Betzel C, Dierks K, Scheiner O, Boltz-Nitulescu G, Keller W, Jensen-Jarolim E.

J Immunol. 2005 Nov 15;175(10):6645-50.

24.

A hybrid molecule resembling the epitope spectrum of grass pollen for allergy vaccination.

Linhart B, Hartl A, Jahn-Schmid B, Verdino P, Keller W, Krauth MT, Valent P, Horak F, Wiedermann U, Thalhamer J, Ebner C, Kraft D, Valenta R.

J Allergy Clin Immunol. 2005 May;115(5):1010-6.

PMID:
15867859
25.

Molecular characterization of polygalacturonases as grass pollen-specific marker allergens: expulsion from pollen via submicronic respirable particles.

Swoboda I, Grote M, Verdino P, Keller W, Singh MB, De Weerd N, Sperr WR, Valent P, Balic N, Reichelt R, Suck R, Fiebig H, Valenta R, Spitzauer S.

J Immunol. 2004 May 15;172(10):6490-500.

26.

Generation of an allergy vaccine by disruption of the three-dimensional structure of the cross-reactive calcium-binding allergen, Phl p 7.

Westritschnig K, Focke M, Verdino P, Goessler W, Keller W, Twardosz A, Mari A, Horak F, Wiedermann U, Hartl A, Thalhamer J, Sperr WR, Valent P, Valenta R.

J Immunol. 2004 May 1;172(9):5684-92.

27.

Circular dichroism analysis of allergens.

Verdino P, Keller W.

Methods. 2004 Mar;32(3):241-8.

PMID:
14962758
28.

Formation of disulfide bonds and homodimers of the major cat allergen Fel d 1 equivalent to the natural allergen by expression in Escherichia coli.

Grönlund H, Bergman T, Sandström K, Alvelius G, Reininger R, Verdino P, Hauswirth A, Liderot K, Valent P, Spitzauer S, Keller W, Valenta R, van Hage-Hamsten M.

J Biol Chem. 2003 Oct 10;278(41):40144-51. Epub 2003 May 5.

29.

Molecular characterization of recombinant T1, a non-allergenic periwinkle (Catharanthus roseus) protein, with sequence similarity to the Bet v 1 plant allergen family.

Laffer S, Hamdi S, Lupinek C, Sperr WR, Valent P, Verdino P, Keller W, Grote M, Hoffmann-Sommergruber K, Scheiner O, Kraft D, Rideau M, Valenta R.

Biochem J. 2003 Jul 1;373(Pt 1):261-9.

30.

Three-dimensional structure of the panallergen Phl p 7.

Verdino P, Westritschnig K, Valenta R, Keller W.

Int Arch Allergy Immunol. 2003 Jan;130(1):10-1. No abstract available.

PMID:
12576729
31.

Characterization of a novel isoform of alpha-nascent polypeptide-associated complex as IgE-defined autoantigen.

Mossabeb R, Seiberler S, Mittermann I, Reininger R, Spitzauer S, Natter S, Verdino P, Keller W, Kraft D, Valenta R.

J Invest Dermatol. 2002 Oct;119(4):820-9.

32.

The cross-reactive calcium-binding pollen allergen, Phl p 7, reveals a novel dimer assembly.

Verdino P, Westritschnig K, Valenta R, Keller W.

EMBO J. 2002 Oct 1;21(19):5007-16.

33.

Combination vaccines for the treatment of grass pollen allergy consisting of genetically engineered hybrid molecules with increased immunogenicity.

Linhart B, Jahn-Schmid B, Verdino P, Keller W, Ebner C, Kraft D, Valenta R.

FASEB J. 2002 Aug;16(10):1301-3. Epub 2002 Jun 21.

PMID:
12154002
34.

Recombinant carp parvalbumin, the major cross-reactive fish allergen: a tool for diagnosis and therapy of fish allergy.

Swoboda I, Bugajska-Schretter A, Verdino P, Keller W, Sperr WR, Valent P, Valenta R, Spitzauer S.

J Immunol. 2002 May 1;168(9):4576-84.

35.

Mutants of the major ryegrass pollen allergen, Lol p 5, with reduced IgE-binding capacity: candidates for grass pollen-specific immunotherapy.

Swoboda I, De Weerd N, Bhalla PL, Niederberger V, Sperr WR, Valent P, Kahlert H, Fiebig H, Verdino P, Keller W, Ebner C, Spitzauer S, Valenta R, Singh MB.

Eur J Immunol. 2002 Jan;32(1):270-80.

36.

Absolute configuration in 4-alkyl- and 4-aryl-3,4-dihydro-2(1H)-pyrimidones: a combined theoretical and experimental investigation.

Uray G, Verdino P, Belaj F, Kappe CO, Fabian WM.

J Org Chem. 2001 Oct 5;66(20):6685-94.

PMID:
11578222
37.

Quantitative structure-enantioselective retention relationships for chromatographic separation of arylalkylcarbinols on Pirkle type chiral stationary phases.

Suzuki T, Timofei S, Iuoras BE, Uray G, Verdino P, Fabian WM.

J Chromatogr A. 2001 Jul 13;922(1-2):13-23.

PMID:
11486858
38.

The essential transfer protein TraM binds to DNA as a tetramer.

Verdino P, Keller W, Strohmaier H, Bischof K, Lindner H, Koraimann G.

J Biol Chem. 1999 Dec 24;274(52):37421-8.

39.
40.

[Hypothalamic amenorrhea. Diagnostic and therapeutic values of pulsatile administration of gonadorelin].

Fenichel P, Guedj AM, Verdino P, Brucker F, Strulo S, Mehouas C, Harter M.

Presse Med. 1988 Jan 23;17(2):61-4. French.

PMID:
2964021
41.

[Pulsatile administration of gonadoliberin by subcutaneous route in the induction of ovulation].

Fenichel P, Harter M, Verdino P, Guedj AM.

Presse Med. 1985 Apr 13;14(15):846. French. No abstract available.

PMID:
3158916
42.

[Primary amenorrhea caused by primary hypothalamic insufficiency. Ovulation induction and pregnancy after pulsatile administration of gonadotropin releasing hormone by a programmed pump].

Fenichel P, Harter M, Verdino P, Strulo S, Renson M, Sudaka P.

Presse Med. 1984 Mar 31;13(14):884-5. French. No abstract available.

PMID:
6231618
43.

[Pregnancy in diabetics. Efficacy and tolerability of the portable insulin pump].

Fenichel P, Verdino P, Melandri E, Boutte P, Gillet JY, Harter M.

Presse Med. 1983 Apr 9;12(16):1020-1. French. No abstract available.

PMID:
6221267
44.

[Amenorrhea and the pill].

Verdino P, Viard R, Harter M.

Lyon Mediterr Med Med Sud Est. 1983 Jan;19(2):7067-74. French.

PMID:
12279701
45.

[Pregnancy, diabetes and the insulin pump. A better prognosis?].

Fenichel P, Verdino P, Melandri E, Boutte P, Harter M, Gillet JY.

J Gynecol Obstet Biol Reprod (Paris). 1983;12(8):883-9. French.

PMID:
6672082

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