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Items: 1 to 50 of 257

1.

Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose.

Meyer JG, Softic S, Basisty N, Rardin MJ, Verdin E, Gibson BW, Ilkayeva O, Newgard CB, Kahn CR, Schilling B.

PLoS One. 2018 Dec 26;13(12):e0208973. doi: 10.1371/journal.pone.0208973. eCollection 2018.

2.

Characterization of the first tenuivirus naturally infecting dicotyledonous plants.

Lecoq H, Wipf-Scheibel C, Verdin E, Desbiez C.

Arch Virol. 2019 Jan;164(1):297-301. doi: 10.1007/s00705-018-4057-6. Epub 2018 Oct 9.

PMID:
30302581
3.

Lavender Decline in France Is Associated with Chronic Infection by Lavender-Specific Strains of "Candidatus Phytoplasma solani".

Sémétey O, Gaudin J, Danet JL, Salar P, Theil S, Fontaine M, Krausz M, Chaisse E, Eveillard S, Verdin E, Foissac X.

Appl Environ Microbiol. 2018 Nov 30;84(24). pii: e01507-18. doi: 10.1128/AEM.01507-18. Print 2018 Dec 15.

4.

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation.

Bruning U, Morales-Rodriguez F, Kalucka J, Goveia J, Taverna F, Queiroz KCS, Dubois C, Cantelmo AR, Chen R, Loroch S, Timmerman E, Caixeta V, Bloch K, Conradi LC, Treps L, Staes A, Gevaert K, Tee A, Dewerchin M, Semenkovich CF, Impens F, Schilling B, Verdin E, Swinnen JV, Meier JL, Kulkarni RA, Sickmann A, Ghesquière B, Schoonjans L, Li X, Mazzone M, Carmeliet P.

Cell Metab. 2018 Dec 4;28(6):866-880.e15. doi: 10.1016/j.cmet.2018.07.019. Epub 2018 Aug 23.

PMID:
30146486
5.

Virus Detection by High-Throughput Sequencing of Small RNAs: Large-Scale Performance Testing of Sequence Analysis Strategies.

Massart S, Chiumenti M, De Jonghe K, Glover R, Haegeman A, Koloniuk I, Komínek P, Kreuze J, Kutnjak D, Lotos L, Maclot F, Maliogka V, Maree HJ, Olivier T, Olmos A, Pooggin MM, Reynard JS, Ruiz-García AB, Safarova D, Schneeberger PHH, Sela N, Turco S, Vainio EJ, Varallyay E, Verdin E, Westenberg M, Brostaux Y, Candresse T.

Phytopathology. 2019 Mar;109(3):488-497. doi: 10.1094/PHYTO-02-18-0067-R. Epub 2019 Feb 7.

PMID:
30070618
6.

Anti-apoptotic Protein BIRC5 Maintains Survival of HIV-1-Infected CD4+ T Cells.

Kuo HH, Ahmad R, Lee GQ, Gao C, Chen HR, Ouyang Z, Szucs MJ, Kim D, Tsibris A, Chun TW, Battivelli E, Verdin E, Rosenberg ES, Carr SA, Yu XG, Lichterfeld M.

Immunity. 2018 Jun 19;48(6):1183-1194.e5. doi: 10.1016/j.immuni.2018.04.004. Epub 2018 May 22.

PMID:
29802019
7.

Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T cells.

Battivelli E, Dahabieh MS, Abdel-Mohsen M, Svensson JP, Tojal Da Silva I, Cohn LB, Gramatica A, Deeks S, Greene WC, Pillai SK, Verdin E.

Elife. 2018 May 1;7. pii: e34655. doi: 10.7554/eLife.34655.

8.

Histone Deacetylase 7 mediates tissue-specific autoimmunity via control of innate effector function in invariant Natural Killer T Cells.

Kasler HG, Lee IS, Lim HW, Verdin E.

Elife. 2018 Apr 17;7. pii: e32109. doi: 10.7554/eLife.32109.

9.

NAD+-dependent deacetylase SIRT3 in adipocytes is dispensable for maintaining normal adipose tissue mitochondrial function and whole body metabolism.

Porter LC, Franczyk MP, Pietka T, Yamaguchi S, Lin JB, Sasaki Y, Verdin E, Apte RS, Yoshino J.

Am J Physiol Endocrinol Metab. 2018 Oct 1;315(4):E520-E530. doi: 10.1152/ajpendo.00057.2018. Epub 2018 Apr 10.

PMID:
29634313
10.

The Mitochondrial Acylome Emerges: Proteomics, Regulation by Sirtuins, and Metabolic and Disease Implications.

Carrico C, Meyer JG, He W, Gibson BW, Verdin E.

Cell Metab. 2018 Mar 6;27(3):497-512. doi: 10.1016/j.cmet.2018.01.016. Review.

11.

Biological and Genetic Characterization of New and Known Necroviruses Causing an Emerging Systemic Necrosis Disease of Corn Salad (Valerianella locusta) in France.

Verdin E, Marais A, Wipf-Scheibel C, Faure C, Pelletier B, David P, Svanella-Dumas L, Poisblaud C, Lecoq H, Candresse T.

Phytopathology. 2018 Aug;108(8):1002-1010. doi: 10.1094/PHYTO-08-17-0284-R. Epub 2018 Jun 18.

PMID:
29490195
12.

Lysine Acetylation Goes Global: From Epigenetics to Metabolism and Therapeutics.

Ali I, Conrad RJ, Verdin E, Ott M.

Chem Rev. 2018 Feb 14;118(3):1216-1252. doi: 10.1021/acs.chemrev.7b00181. Epub 2018 Feb 6. Review.

PMID:
29405707
13.

Sirt4 is a mitochondrial regulator of metabolism and lifespan in Drosophila melanogaster.

Wood JG, Schwer B, Wickremesinghe PC, Hartnett DA, Burhenn L, Garcia M, Li M, Verdin E, Helfand SL.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1564-1569. doi: 10.1073/pnas.1720673115. Epub 2018 Jan 29.

14.

Defining Metabolic and Nonmetabolic Regulation of Histone Acetylation by NSAID Chemotypes.

Shrimp JH, Garlick JM, Tezil T, Sorum AW, Worth AJ, Blair IA, Verdin E, Snyder NW, Meier JL.

Mol Pharm. 2018 Mar 5;15(3):729-736. doi: 10.1021/acs.molpharmaceut.7b00943. Epub 2017 Dec 29.

15.

Metabolic reprogramming of human CD8+ memory T cells through loss of SIRT1.

Jeng MY, Hull PA, Fei M, Kwon HS, Tsou CL, Kasler H, Ng CP, Gordon DE, Johnson J, Krogan N, Verdin E, Ott M.

J Exp Med. 2018 Jan 2;215(1):51-62. doi: 10.1084/jem.20161066. Epub 2017 Nov 30.

16.

Intestinal SIRT3 overexpression in mice improves whole body glucose homeostasis independent of body weight.

Ramachandran D, Clara R, Fedele S, Hu J, Lackzo E, Huang JY, Verdin E, Langhans W, Mansouri A.

Mol Metab. 2017 Oct;6(10):1264-1273. doi: 10.1016/j.molmet.2017.07.009. Epub 2017 Jul 18.

17.

Sirtuin-3 Promotes Adipogenesis, Osteoclastogenesis, and Bone Loss in Aging Male Mice.

Ho L, Wang L, Roth TM, Pan Y, Verdin EM, Hsiao EC, Nissenson RA.

Endocrinology. 2017 Sep 1;158(9):2741-2753. doi: 10.1210/en.2016-1739.

18.

Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice.

Newman JC, Covarrubias AJ, Zhao M, Yu X, Gut P, Ng CP, Huang Y, Haldar S, Verdin E.

Cell Metab. 2017 Sep 5;26(3):547-557.e8. doi: 10.1016/j.cmet.2017.08.004.

19.

Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet.

Tognini P, Murakami M, Liu Y, Eckel-Mahan KL, Newman JC, Verdin E, Baldi P, Sassone-Corsi P.

Cell Metab. 2017 Sep 5;26(3):523-538.e5. doi: 10.1016/j.cmet.2017.08.015.

20.

β-Hydroxybutyrate: A Signaling Metabolite.

Newman JC, Verdin E.

Annu Rev Nutr. 2017 Aug 21;37:51-76. doi: 10.1146/annurev-nutr-071816-064916. Review.

PMID:
28826372
21.

New species in the papaya ringspot virus cluster: Insights into the evolution of the PRSV lineage.

Desbiez C, Wipf-Scheibel C, Millot P, Verdin E, Dafalla G, Lecoq H.

Virus Res. 2017 Sep 15;241:88-94. doi: 10.1016/j.virusres.2017.06.022. Epub 2017 Jun 29.

PMID:
28669763
22.

Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor.

Fernández-Del-Río L, Nag A, Gutiérrez Casado E, Ariza J, Awad AM, Joseph AI, Kwon O, Verdin E, de Cabo R, Schneider C, Torres JZ, Burón MI, Clarke CF, Villalba JM.

Free Radic Biol Med. 2017 Sep;110:176-187. doi: 10.1016/j.freeradbiomed.2017.06.006. Epub 2017 Jun 9.

23.

Sequencing viral siRNAs to identify previously undescribed viruses and viroids in a panel of ornamental plant samples structured as a matrix of pools.

Verdin E, Wipf-Scheibel C, Gognalons P, Aller F, Jacquemond M, Tepfer M.

Virus Res. 2017 Sep 15;241:19-28. doi: 10.1016/j.virusres.2017.05.019. Epub 2017 May 31. Review.

PMID:
28576697
24.

A PET Imaging Strategy to Visualize Activated T Cells in Acute Graft-versus-Host Disease Elicited by Allogenic Hematopoietic Cell Transplant.

Ronald JA, Kim BS, Gowrishankar G, Namavari M, Alam IS, D'Souza A, Nishikii H, Chuang HY, Ilovich O, Lin CF, Reeves R, Shuhendler A, Hoehne A, Chan CT, Baker J, Yaghoubi SS, VanBrocklin HF, Hawkins R, Franc BL, Jivan S, Slater JB, Verdin EF, Gao KT, Benjamin J, Negrin R, Gambhir SS.

Cancer Res. 2017 Jun 1;77(11):2893-2902. doi: 10.1158/0008-5472.CAN-16-2953.

25.

Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells.

Myers DR, Lau T, Markegard E, Lim HW, Kasler H, Zhu M, Barczak A, Huizar JP, Zikherman J, Erle DJ, Zhang W, Verdin E, Roose JP.

Cell Rep. 2017 May 23;19(8):1558-1571. doi: 10.1016/j.celrep.2017.04.076.

26.

Long-term calorie restriction in humans is not associated with indices of delayed immunologic aging: A descriptive study.

Tomiyama AJ, Milush JM, Lin J, Flynn JM, Kapahi P, Verdin E, Sinclair E, Melov S, Epel ES.

Nutr Healthy Aging. 2017 Mar 31;4(2):147-156. doi: 10.3233/NHA-160017.

27.

The mTOR Complex Controls HIV Latency.

Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E.

Cell Host Microbe. 2016 Dec 14;20(6):785-797. doi: 10.1016/j.chom.2016.11.001.

28.

SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage.

Bindu S, Pillai VB, Kanwal A, Samant S, Mutlu GM, Verdin E, Dulin N, Gupta MP.

Am J Physiol Lung Cell Mol Physiol. 2017 Jan 1;312(1):L68-L78. doi: 10.1152/ajplung.00188.2016. Epub 2016 Nov 4.

29.

Characterization of a new cucurbit-infecting ipomovirus from Sudan.

Desbiez C, Verdin E, Tepfer M, Wipf-Scheibel C, Millot P, Dafalla G, Lecoq H.

Arch Virol. 2016 Oct;161(10):2913-5. doi: 10.1007/s00705-016-2981-x. Epub 2016 Jul 18.

PMID:
27430562
30.

LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV.

Vranckx LS, Demeulemeester J, Saleh S, Boll A, Vansant G, Schrijvers R, Weydert C, Battivelli E, Verdin E, Cereseto A, Christ F, Gijsbers R, Debyser Z.

EBioMedicine. 2016 Jun;8:248-264. doi: 10.1016/j.ebiom.2016.04.039. Epub 2016 May 13.

31.

Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity.

Shirakawa K, Wang L, Man N, Maksimoska J, Sorum AW, Lim HW, Lee IS, Shimazu T, Newman JC, Schröder S, Ott M, Marmorstein R, Meier J, Nimer S, Verdin E.

Elife. 2016 May 31;5. pii: e11156. doi: 10.7554/eLife.11156.

32.

A genetically novel, narrow-host-range isolate of cucumber mosaic virus (CMV) from rosemary.

Tepfer M, Girardot G, Fénéant L, Ben Tamarzizt H, Verdin E, Moury B, Jacquemond M.

Arch Virol. 2016 Jul;161(7):2013-7. doi: 10.1007/s00705-016-2874-z. Epub 2016 Apr 30.

PMID:
27138549
33.

Characterization and occurrence of squash chlorotic leaf spot virus, a tentative new torradovirus infecting cucurbits in Sudan.

Lecoq H, Verdin E, Tepfer M, Wipf-Scheibel C, Millot P, Dafalla G, Desbiez C.

Arch Virol. 2016 Jun;161(6):1651-5. doi: 10.1007/s00705-016-2797-8. Epub 2016 Mar 3.

PMID:
26935919
34.

Aging Promotes Sirtuin 3-Dependent Cartilage Superoxide Dismutase 2 Acetylation and Osteoarthritis.

Fu Y, Kinter M, Hudson J, Humphries KM, Lane RS, White JR, Hakim M, Pan Y, Verdin E, Griffin TM.

Arthritis Rheumatol. 2016 Aug;68(8):1887-98. doi: 10.1002/art.39618.

35.

NAD⁺ in aging, metabolism, and neurodegeneration.

Verdin E.

Science. 2015 Dec 4;350(6265):1208-13. doi: 10.1126/science.aac4854. Review.

PMID:
26785480
36.

A Novel Sirtuin-3 Inhibitor, LC-0296, Inhibits Cell Survival and Proliferation, and Promotes Apoptosis of Head and Neck Cancer Cells.

Alhazzazi TY, Kamarajan P, Xu Y, Ai T, Chen L, Verdin E, Kapila YL.

Anticancer Res. 2016 Jan;36(1):49-60.

37.

Measurement of absolute myocardial blood flow in humans using dynamic cardiac SPECT and 99mTc-tetrofosmin: Method and validation.

Shrestha U, Sciammarella M, Alhassen F, Yeghiazarians Y, Ellin J, Verdin E, Boyle A, Seo Y, Botvinick EH, Gullberg GT.

J Nucl Cardiol. 2017 Feb;24(1):268-277. doi: 10.1007/s12350-015-0320-3. Epub 2015 Dec 29.

38.

Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype.

Wiley CD, Velarde MC, Lecot P, Liu S, Sarnoski EA, Freund A, Shirakawa K, Lim HW, Davis SS, Ramanathan A, Gerencser AA, Verdin E, Campisi J.

Cell Metab. 2016 Feb 9;23(2):303-14. doi: 10.1016/j.cmet.2015.11.011. Epub 2015 Dec 10.

39.

SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β.

Sundaresan NR, Bindu S, Pillai VB, Samant S, Pan Y, Huang JY, Gupta M, Nagalingam RS, Wolfgeher D, Verdin E, Gupta MP.

Mol Cell Biol. 2015 Dec 14;36(5):678-92. doi: 10.1128/MCB.00586-15.

40.

Correction: Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency.

Rafati H, Parra M, Hakre S, Moshkin Y, Verdin E, Mahmoudi T.

PLoS Biol. 2015 Nov 16;13(11):e1002302. doi: 10.1371/journal.pbio.1002302. eCollection 2015 Nov.

41.

Correcting for respiratory motion in liver PET/MRI: preliminary evaluation of the utility of bellows and navigated hepatobiliary phase imaging.

Hope TA, Verdin EF, Bergsland EK, Ohliger MA, Corvera CU, Nakakura EK.

EJNMMI Phys. 2015 Dec;2(1):21. doi: 10.1186/s40658-015-0125-0. Epub 2015 Sep 18.

42.

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.

Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, Johnson J, Krogan N, Shamloo M, Gestwicki J, Masliah E, Verdin E, Gan L.

Nat Med. 2015 Oct;21(10):1154-62. doi: 10.1038/nm.3951. Epub 2015 Sep 21.

43.

SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target.

Nishida Y, Rardin MJ, Carrico C, He W, Sahu AK, Gut P, Najjar R, Fitch M, Hellerstein M, Gibson BW, Verdin E.

Mol Cell. 2015 Jul 16;59(2):321-32. doi: 10.1016/j.molcel.2015.05.022. Epub 2015 Jun 11.

44.

HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells.

Chavez L, Calvanese V, Verdin E.

PLoS Pathog. 2015 Jun 11;11(6):e1004955. doi: 10.1371/journal.ppat.1004955. eCollection 2015 Jun.

45.

SIRT1 deacetylates RORγt and enhances Th17 cell generation.

Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E.

J Exp Med. 2015 Jun 1;212(6):973. doi: 10.1084/jem.2013237805062015c. Epub 2015 May 18. No abstract available.

46.

SIRT1 deacetylates RORγt and enhances Th17 cell generation.

Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, Xiao C, Littman DR, Ott M, Verdin E.

J Exp Med. 2015 May 4;212(5):607-17. doi: 10.1084/jem.20132378. Epub 2015 Apr 27. Erratum in: J Exp Med. 2015 Jun 1;212(6):973.

47.

MicroRNA-155 Reinforces HIV Latency.

Ruelas DS, Chan JK, Oh E, Heidersbach AJ, Hebbeler AM, Chavez L, Verdin E, Rape M, Greene WC.

J Biol Chem. 2015 May 29;290(22):13736-48. doi: 10.1074/jbc.M115.641837. Epub 2015 Apr 14.

48.

SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase.

Zhang Y, Bharathi SS, Rardin MJ, Uppala R, Verdin E, Gibson BW, Goetzman ES.

PLoS One. 2015 Mar 26;10(3):e0122297. doi: 10.1371/journal.pone.0122297. eCollection 2015.

49.

Understanding HIV latency: the road to an HIV cure.

Dahabieh MS, Battivelli E, Verdin E.

Annu Rev Med. 2015;66:407-21. doi: 10.1146/annurev-med-092112-152941. Review.

50.

50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond.

Verdin E, Ott M.

Nat Rev Mol Cell Biol. 2015 Apr;16(4):258-64. doi: 10.1038/nrm3931. Epub 2014 Dec 30. Review.

PMID:
25549891

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