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Items: 46

1.

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

Bouguenina H, Salaun D, Mangon A, Muller L, Baudelet E, Camoin L, Tachibana T, Cianférani S, Audebert S, Verdier-Pinard P, Badache A.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10687-E10696. doi: 10.1073/pnas.1705682114. Epub 2017 Nov 21.

2.

Septin 9_i2 is downregulated in tumors, impairs cancer cell migration and alters subnuclear actin filaments.

Verdier-Pinard P, Salaun D, Bouguenina H, Shimada S, Pophillat M, Audebert S, Agavnian E, Coslet S, Charafe-Jauffret E, Tachibana T, Badache A.

Sci Rep. 2017 Mar 24;7:44976. doi: 10.1038/srep44976.

3.

Eribulin targets a ch-TOG-dependent directed migration of cancer cells.

Chanez B, Gonçalves A, Badache A, Verdier-Pinard P.

Oncotarget. 2015 Dec 8;6(39):41667-78. doi: 10.18632/oncotarget.6147.

4.

ErbB2-dependent chemotaxis requires microtubule capture and stabilization coordinated by distinct signaling pathways.

Benseddik K, Sen Nkwe N, Daou P, Verdier-Pinard P, Badache A.

PLoS One. 2013;8(1):e55211. doi: 10.1371/journal.pone.0055211. Epub 2013 Jan 29.

5.

Characterization of a human βV-tubulin antibody and expression of this isotype in normal and malignant human tissue.

Chao SK, Wang Y, Verdier-Pinard P, Yang CP, Liu L, Rodriguez-Gabin A, McDaid HM, Horwitz SB.

Cytoskeleton (Hoboken). 2012 Aug;69(8):566-76. doi: 10.1002/cm.21043. Epub 2012 Jul 2.

6.

Tyrosine-dependent capture of CAP-Gly domain-containing proteins in complex mixture by EB1 C-terminal peptidic probes.

Calligaris D, Manatschal C, Marcellin M, Villard C, Monsarrat B, Burlet-Schiltz O, Steinmetz MO, Braguer D, Lafitte D, Verdier-Pinard P.

J Proteomics. 2012 Jun 27;75(12):3605-16. doi: 10.1016/j.jprot.2012.04.006. Epub 2012 Apr 21.

PMID:
22543185
7.

Septin 9 isoform expression, localization and epigenetic changes during human and mouse breast cancer progression.

Connolly D, Yang Z, Castaldi M, Simmons N, Oktay MH, Coniglio S, Fazzari MJ, Verdier-Pinard P, Montagna C.

Breast Cancer Res. 2011 Aug 10;13(4):R76. doi: 10.1186/bcr2924.

8.

Septin roles in tumorigenesis.

Connolly D, Abdesselam I, Verdier-Pinard P, Montagna C.

Biol Chem. 2011 Aug;392(8-9):725-38. doi: 10.1515/BC.2011.073. Epub 2011 Jul 11. Review.

PMID:
21740328
9.

MALDI in-source decay of high mass protein isoforms: application to alpha- and beta-tubulin variants.

Calligaris D, Villard C, Terras L, Braguer D, Verdier-Pinard P, Lafitte D.

Anal Chem. 2010 Jul 15;82(14):6176-84. doi: 10.1021/ac100996v.

PMID:
20552990
10.

Methods in tubulin proteomics.

Miller LM, Xiao H, Burd B, Horwitz SB, Angeletti RH, Verdier-Pinard P.

Methods Cell Biol. 2010;95:105-26. doi: 10.1016/S0091-679X(10)95007-3. Review.

11.

Microtubule targeting agents: from biophysics to proteomics.

Calligaris D, Verdier-Pinard P, Devred F, Villard C, Braguer D, Lafitte D.

Cell Mol Life Sci. 2010 Apr;67(7):1089-104. doi: 10.1007/s00018-009-0245-6. Epub 2010 Jan 28. Review.

PMID:
20107862
12.

Post-translational modifications to Toxoplasma gondii alpha- and beta-tubulins include novel C-terminal methylation.

Xiao H, El Bissati K, Verdier-Pinard P, Burd B, Zhang H, Kim K, Fiser A, Angeletti RH, Weiss LM.

J Proteome Res. 2010 Jan;9(1):359-72. doi: 10.1021/pr900699a.

13.

Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization.

Khrapunovich-Baine M, Menon V, Verdier-Pinard P, Smith AB 3rd, Angeletti RH, Fiser A, Horwitz SB, Xiao H.

Biochemistry. 2009 Dec 15;48(49):11664-77. doi: 10.1021/bi901351q.

14.

Tubulin proteomics: towards breaking the code.

Verdier-Pinard P, Pasquier E, Xiao H, Burd B, Villard C, Lafitte D, Miller LM, Angeletti RH, Horwitz SB, Braguer D.

Anal Biochem. 2009 Jan 15;384(2):197-206. doi: 10.1016/j.ab.2008.09.020. Epub 2008 Sep 18. Review. No abstract available.

15.

Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites.

Honoré S, Pagano A, Gauthier G, Bourgarel-Rey V, Verdier-Pinard P, Civiletti K, Kruczynski A, Braguer D.

Mol Cancer Ther. 2008 Jul;7(7):2080-9. doi: 10.1158/1535-7163.MCT-08-0156.

16.

Increased levels of a unique post-translationally modified betaIVb-tubulin isotype in liver cancer.

Miller LM, Menthena A, Chatterjee C, Verdier-Pinard P, Novikoff PM, Horwitz SB, Angeletti RH.

Biochemistry. 2008 Jul 15;47(28):7572-82. doi: 10.1021/bi8005225. Epub 2008 Jun 21.

17.

Aneuploidy acts both oncogenically and as a tumor suppressor.

Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, Cleveland DW.

Cancer Cell. 2007 Jan;11(1):25-36. Epub 2006 Dec 28.

18.

Comparison of the activities of the truncated halichondrin B analog NSC 707389 (E7389) with those of the parent compound and a proposed binding site on tubulin.

Dabydeen DA, Burnett JC, Bai R, Verdier-Pinard P, Hickford SJ, Pettit GR, Blunt JW, Munro MH, Gussio R, Hamel E.

Mol Pharmacol. 2006 Dec;70(6):1866-75. Epub 2006 Aug 29.

PMID:
16940412
19.

Insights into the mechanism of microtubule stabilization by Taxol.

Xiao H, Verdier-Pinard P, Fernandez-Fuentes N, Burd B, Angeletti R, Fiser A, Horwitz SB, Orr GA.

Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10166-10173. doi: 10.1073/pnas.0603704103. Epub 2006 Jun 26.

20.

4,5-Diaryl-1H-pyrrole-2-carboxylates as combretastatin A-4/lamellarin T hybrids: synthesis and evaluation as anti-mitotic and cytotoxic agents.

Banwell MG, Hamel E, Hockless DC, Verdier-Pinard P, Willis AC, Wong DJ.

Bioorg Med Chem. 2006 Jul 1;14(13):4627-38. Epub 2006 Feb 28.

PMID:
16510287
21.

Detection of human betaV-tubulin expression in epithelial cancer cell lines by tubulin proteomics.

Verdier-Pinard P, Shahabi S, Wang F, Burd B, Xiao H, Goldberg GL, Orr GA, Horwitz SB.

Biochemistry. 2005 Dec 6;44(48):15858-70.

PMID:
16313188
22.

A highly epothilone B-resistant A549 cell line with mutations in tubulin that confer drug dependence.

Yang CP, Verdier-Pinard P, Wang F, Lippaine-Horvath E, He L, Li D, Höfle G, Ojima I, Orr GA, Horwitz SB.

Mol Cancer Ther. 2005 Jun;4(6):987-95.

23.

Mechanisms of Taxol resistance related to microtubules.

Orr GA, Verdier-Pinard P, McDaid H, Horwitz SB.

Oncogene. 2003 Oct 20;22(47):7280-95. Review.

24.

Direct analysis of tubulin expression in cancer cell lines by electrospray ionization mass spectrometry.

Verdier-Pinard P, Wang F, Burd B, Angeletti RH, Horwitz SB, Orr GA.

Biochemistry. 2003 Oct 21;42(41):12019-27.

PMID:
14556633
25.

Total synthesis of (+/-)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi.

Banwell MG, Edwards AJ, Jolliffe KA, Smith JA, Hamel E, Verdier-Pinard P.

Org Biomol Chem. 2003 Jan 21;1(2):296-305.

PMID:
12929425
26.

Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry.

Verdier-Pinard P, Wang F, Martello L, Burd B, Orr GA, Horwitz SB.

Biochemistry. 2003 May 13;42(18):5349-57.

PMID:
12731876
27.

Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation.

Martello LA, Verdier-Pinard P, Shen HJ, He L, Torres K, Orr GA, Horwitz SB.

Cancer Res. 2003 Mar 15;63(6):1207-13.

28.

Hypoestoxide, a natural nonmutagenic diterpenoid with antiangiogenic and antitumor activity: possible mechanisms of action.

Ojo-Amaize EA, Nchekwube EJ, Cottam HB, Bai R, Verdier-Pinard P, Kakkanaiah VN, Varner JA, Leoni L, Okogun JI, Adesomoju AA, Oyemade OA, Hamel E.

Cancer Res. 2002 Jul 15;62(14):4007-14.

29.

Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly.

Marquez BL, Watts KS, Yokochi A, Roberts MA, Verdier-Pinard P, Jimenez JI, Hamel E, Scheuer PJ, Gerwick WH.

J Nat Prod. 2002 Jun;65(6):866-71.

PMID:
12088429
30.

Antifungal and cancer cell growth inhibitory activities of 1-(3',4',5'-trimethoxyphenyl)-2-nitro-ethylene.

Pettit RK, Hamel E, Verdier-Pinard P, Roberson RW, Hazen KC, Pettit GR, Crews LC.

Mycoses. 2002 Apr;45(3-4):65-74.

PMID:
12000503
31.

Design, synthesis, and biological evaluation of a series of lavendustin A analogues that inhibit EGFR and Syk tyrosine kinases, as well as tubulin polymerization.

Mu F, Coffing SL, Riese DJ 2nd, Geahlen RL, Verdier-Pinard P, Hamel TE, Johnson J, Cushman M.

J Med Chem. 2001 Feb 1;44(3):441-52.

PMID:
11462983
32.

Antineoplastic agents 442. Synthesis and biological activities of dioxostatin.

Pettit GR, Lippert JW 3rd, Boyd MR, Verdier-Pinard P, Hamel E.

Anticancer Drug Des. 2000 Oct;15(5):361-71.

PMID:
11354312
33.

[Combretastatin A4 phosphate].

Verdier-Pinard P, Lansiaux A, Bailly C.

Bull Cancer. 2001 Mar;88(3):235-9. Review. French. No abstract available.

35.

Dolastatin 11, a marine depsipeptide, arrests cells at cytokinesis and induces hyperpolymerization of purified actin.

Bai R, Verdier-Pinard P, Gangwar S, Stessman CC, McClure KJ, Sausville EA, Pettit GR, Bates RB, Hamel E.

Mol Pharmacol. 2001 Mar;59(3):462-9.

PMID:
11179440
36.

Synthesis and biological evaluation of aryl azide derivatives of combretastatin A-4 as molecular probes for tubulin.

Pinney KG, Mejia MP, Villalobos VM, Rosenquist BE, Pettit GR, Verdier-Pinard P, Hamel E.

Bioorg Med Chem. 2000 Oct;8(10):2417-25.

PMID:
11058036
37.

A steroid derivative with paclitaxel-like effects on tubulin polymerization.

Verdier-Pinard P, Wang Z, Mohanakrishnan AK, Cushman M, Hamel E.

Mol Pharmacol. 2000 Mar;57(3):568-75.

PMID:
10692498
38.

Sustained intracellular retention of dolastatin 10 causes its potent antimitotic activity.

Verdier-Pinard P, Kepler JA, Pettit GR, Hamel E.

Mol Pharmacol. 2000 Jan;57(1):180-7.

PMID:
10617693
39.

Differential in vitro association of vinca alkaloid-induced tubulin spiral filaments into aggregated spirals.

Verdier-Pinard P, Garès M, Wright M.

Biochem Pharmacol. 1999 Sep 15;58(6):959-71.

PMID:
10509748
40.

Biosynthesis of radiolabeled curacin A and its rapid and apparently irreversible binding to the colchicine site of tubulin.

Verdier-Pinard P, Sitachitta N, Rossi JV, Sackett DL, Gerwick WH, Hamel E.

Arch Biochem Biophys. 1999 Oct 1;370(1):51-8.

PMID:
10496976
41.

Curacin D, an antimitotic agent from the marine cyanobacterium Lyngbya majuscula.

Márquez B, Verdier-Pinard P, Hamel E, Gerwick WH.

Phytochemistry. 1998 Dec;49(8):2387-9.

PMID:
9887531
42.

Antineoplastic agents. 379. Synthesis of phenstatin phosphate.

Pettit GR, Toki B, Herald DL, Verdier-Pinard P, Boyd MR, Hamel E, Pettit RK.

J Med Chem. 1998 May 7;41(10):1688-95.

PMID:
9572894
43.

Antitumor agents--CLXXV. Anti-tubulin action of (+)-thiocolchicine prepared by partial synthesis.

Shi Q, Verdier-Pinard P, Brossi A, Hamel E, Lee KH.

Bioorg Med Chem. 1997 Dec;5(12):2277-82.

PMID:
9459025
44.

Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells.

Verdier-Pinard P, Lai JY, Yoo HD, Yu J, Marquez B, Nagle DG, Nambu M, White JD, Falck JR, Gerwick WH, Day BW, Hamel E.

Mol Pharmacol. 1998 Jan;53(1):62-76.

PMID:
9443933
45.

Antitumor agents. 172. Synthesis and biological evaluation of novel deacetamidothiocolchicin-7-ols and ester analogs as antitubulin agents.

Shi Q, Verdier-Pinard P, Brossi A, Hamel E, McPhail AT, Lee KH.

J Med Chem. 1997 Mar 14;40(6):961-6.

PMID:
9083485
46.

Differential in vitro action of S-12363, a new vinblastine derivative, and of its epimer on microtubule proteins.

Wright M, Garès M, Verdier-Pinard P, Moisand A, Berlion M, Legrand JJ, Bizzari JP.

Cancer Chemother Pharmacol. 1991;28(6):434-40.

PMID:
1934248

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