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Items: 36


Reasons for delayed antiretroviral therapy (ART) initiation in the era of early ART initiation guidelines: a retrospective service evaluation.

Lee MJ, Venturelli S, McKenna W, Teh J, Negedu O, Florman KE, Musbahi E, Bailey AC, Mackie NE, Fox J, Fidler S.

Int J STD AIDS. 2019 Mar;30(4):415-418. doi: 10.1177/0956462418814985. Epub 2019 Jan 8.


6- and 8-Prenylnaringenin, Novel Natural Histone Deacetylase Inhibitors Found in Hops, Exert Antitumor Activity on Melanoma Cells.

Venturelli S, Niessner H, Sinnberg T, Berger A, Burkard M, Urmann C, Donaubauer K, Böcker A, Leischner C, Riepl H, Frank J, Lauer UM, Garbe C, Busch C.

Cell Physiol Biochem. 2018;51(2):543-556. doi: 10.1159/000495275. Epub 2018 Nov 20.


Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel-associated retinopathy.

Burkard M, Kohl S, Krätzig T, Tanimoto N, Brennenstuhl C, Bausch AE, Junger K, Reuter P, Sothilingam V, Beck SC, Huber G, Ding XQ, Mayer AK, Baumann B, Weisschuh N, Zobor D, Hahn GA, Kellner U, Venturelli S, Becirovic E, Charbel Issa P, Koenekoop RK, Rudolph G, Heckenlively J, Sieving P, Weleber RG, Hamel C, Zong X, Biel M, Lukowski R, Seeliger MW, Michalakis S, Wissinger B, Ruth P.

J Clin Invest. 2018 Dec 3;128(12):5663-5675. doi: 10.1172/JCI96098. Epub 2018 Nov 12.


The Oral Bioavailability of 8-Prenylnaringenin from Hops (Humulus Lupulus L.) in Healthy Women and Men is Significantly Higher than that of its Positional Isomer 6-Prenylnaringenin in a Randomized Crossover Trial.

Calvo-Castro LA, Burkard M, Sus N, Scheubeck G, Leischner C, Lauer UM, Bosy-Westphal A, Hund V, Busch C, Venturelli S, Frank J.

Mol Nutr Food Res. 2018 Apr;62(7):e1700838. doi: 10.1002/mnfr.201700838. Epub 2018 Mar 1.


Cellular senescence in gastrointestinal diseases: from pathogenesis to therapeutics.

Frey N, Venturelli S, Zender L, Bitzer M.

Nat Rev Gastroenterol Hepatol. 2018 Feb;15(2):81-95. doi: 10.1038/nrgastro.2017.146. Epub 2017 Nov 29. Review.


Dietary flavonoids and modulation of natural killer cells: implications in malignant and viral diseases.

Burkard M, Leischner C, Lauer UM, Busch C, Venturelli S, Frank J.

J Nutr Biochem. 2017 Aug;46:1-12. doi: 10.1016/j.jnutbio.2017.01.006. Epub 2017 Jan 24. Review.


Novel epi-virotherapeutic treatment of pancreatic cancer combining the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus.

Ellerhoff TP, Berchtold S, Venturelli S, Burkard M, Smirnow I, Wulff T, Lauer UM.

Int J Oncol. 2016 Nov;49(5):1931-1944. doi: 10.3892/ijo.2016.3675. Epub 2016 Aug 31.


Prenylated chalcones and flavonoids for the prevention and treatment of cancer.

Venturelli S, Burkard M, Biendl M, Lauer UM, Frank J, Busch C.

Nutrition. 2016 Nov-Dec;32(11-12):1171-8. doi: 10.1016/j.nut.2016.03.020. Epub 2016 Apr 8. Review.


Nutritional immunology: function of natural killer cells and their modulation by resveratrol for cancer prevention and treatment.

Leischner C, Burkard M, Pfeiffer MM, Lauer UM, Busch C, Venturelli S.

Nutr J. 2016 May 4;15(1):47. doi: 10.1186/s12937-016-0167-8. Review.


Allelochemicals of the phenoxazinone class act at physiologically relevant concentrations.

Venturelli S, Petersen S, Langenecker T, Weigel D, Lauer UM, Becker C.

Plant Signal Behav. 2016 May 3;11(5):e1176818. doi: 10.1080/15592324.2016.1176818.


Plants Release Precursors of Histone Deacetylase Inhibitors to Suppress Growth of Competitors.

Venturelli S, Belz RG, Kämper A, Berger A, von Horn K, Wegner A, Böcker A, Zabulon G, Langenecker T, Kohlbacher O, Barneche F, Weigel D, Lauer UM, Bitzer M, Becker C.

Plant Cell. 2015 Nov;27(11):3175-89. doi: 10.1105/tpc.15.00585. Epub 2015 Nov 3.


The exclusion of people living with HIV (PLWH) from clinical trials in lymphoma.

Venturelli S, Dalla Pria A, Stegmann K, Smith P, Bower M.

Br J Cancer. 2015 Sep 15;113(6):861-3. doi: 10.1038/bjc.2015.301. Epub 2015 Aug 27.


Metabolic alteration--Overcoming therapy resistance in gastric cancer via PGK-1 inhibition in a combined therapy with standard chemotherapeutics.

Schneider CC, Archid R, Fischer N, Bühler S, Venturelli S, Berger A, Burkard M, Kirschniak A, Bachmann R, Königsrainer A, Glatzle J, Zieker D.

Int J Surg. 2015 Oct;22:92-8. doi: 10.1016/j.ijsu.2015.08.020. Epub 2015 Aug 19.


Epigenetic activities of flavonoids in the prevention and treatment of cancer.

Busch C, Burkard M, Leischner C, Lauer UM, Frank J, Venturelli S.

Clin Epigenetics. 2015 Jul 10;7:64. doi: 10.1186/s13148-015-0095-z. eCollection 2015.


Molecular mechanisms of pharmacological doses of ascorbate on cancer cells.

Venturelli S, Sinnberg TW, Niessner H, Busch C.

Wien Med Wochenschr. 2015 Jun;165(11-12):251-7. doi: 10.1007/s10354-015-0356-7. Epub 2015 Jun 12. Review.


Anti-proliferative activity of hop-derived prenylflavonoids against human cancer cell lines.

Busch C, Noor S, Leischner C, Burkard M, Lauer UM, Venturelli S.

Wien Med Wochenschr. 2015 Jun;165(11-12):258-61. doi: 10.1007/s10354-015-0355-8. Epub 2015 Apr 30. Review.


Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma.

Ruf B, Berchtold S, Venturelli S, Burkard M, Smirnow I, Prenzel T, Henning SW, Lauer UM.

Mol Ther Oncolytics. 2015 Oct 7;2:15019. doi: 10.1038/mto.2015.19. eCollection 2015.


Epigenetic impacts of ascorbate on human metastatic melanoma cells.

Venturelli S, Sinnberg TW, Berger A, Noor S, Levesque MP, Böcker A, Niessner H, Lauer UM, Bitzer M, Garbe C, Busch C.

Front Oncol. 2014 Aug 25;4:227. doi: 10.3389/fonc.2014.00227. eCollection 2014.


The ROS-induced cytotoxicity of ascorbate is attenuated by hypoxia and HIF-1alpha in the NCI60 cancer cell lines.

Sinnberg T, Noor S, Venturelli S, Berger A, Schuler P, Garbe C, Busch C.

J Cell Mol Med. 2014 Mar;18(3):530-41. doi: 10.1111/jcmm.12207. Epub 2013 Dec 14.


Resveratrol as a pan-HDAC inhibitor alters the acetylation status of histone [corrected] proteins in human-derived hepatoblastoma cells.

Venturelli S, Berger A, Böcker A, Busch C, Weiland T, Noor S, Leischner C, Schleicher S, Mayer M, Weiss TS, Bischoff SC, Lauer UM, Bitzer M.

PLoS One. 2013 Aug 30;8(8):e73097. doi: 10.1371/journal.pone.0073097. eCollection 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/5b9a8614-1009-40ca-b90b-db817fe445c9.


Differential induction of apoptosis and senescence by the DNA methyltransferase inhibitors 5-azacytidine and 5-aza-2'-deoxycytidine in solid tumor cells.

Venturelli S, Berger A, Weiland T, Essmann F, Waibel M, Nuebling T, Häcker S, Schenk M, Schulze-Osthoff K, Salih HR, Fulda S, Sipos B, Johnstone RW, Lauer UM, Bitzer M.

Mol Cancer Ther. 2013 Oct;12(10):2226-36. doi: 10.1158/1535-7163.MCT-13-0137. Epub 2013 Aug 7.


Enhanced killing of therapy-induced senescent tumor cells by oncolytic measles vaccine viruses.

Weiland T, Lampe J, Essmann F, Venturelli S, Berger A, Bossow S, Berchtold S, Schulze-Osthoff K, Lauer UM, Bitzer M.

Int J Cancer. 2014 Jan 1;134(1):235-43. doi: 10.1002/ijc.28350. Epub 2013 Aug 7.


Selective protection of human liver tissue in TNF-targeting of cancers of the liver by transient depletion of adenosine triphosphate.

Weiland T, Klein K, Zimmermann M, Speicher T, Venturelli S, Berger A, Bantel H, Königsrainer A, Schenk M, Weiss TS, Wendel A, Schwab M, Bitzer M, Lauer UM.

PLoS One. 2012;7(12):e52496. doi: 10.1371/journal.pone.0052496. Epub 2012 Dec 18.


Kaempferol, a new nutrition-derived pan-inhibitor of human histone deacetylases.

Berger A, Venturelli S, Kallnischkies M, Böcker A, Busch C, Weiland T, Noor S, Leischner C, Weiss TS, Lauer UM, Bischoff SC, Bitzer M.

J Nutr Biochem. 2013 Jun;24(6):977-85. doi: 10.1016/j.jnutbio.2012.07.001. Epub 2012 Nov 14.


Cytotoxicity of new duplex drugs linking 3'-C-ethynylcytidine and 5-fluor-2'-deoxyuridine against human melanoma cells.

Schott S, Niessner H, Sinnberg T, Venturelli S, Berger A, Ikenberg K, Villanueva J, Meier F, Garbe C, Busch C.

Int J Cancer. 2012 Nov 1;131(9):2165-74. doi: 10.1002/ijc.27476. Epub 2012 Mar 15.


Kinetic tracking of therapy-induced senescence using the real-time cell analyzer single plate system.

Weiland T, Berger A, Essmann F, Lauer UM, Bitzer M, Venturelli S.

Assay Drug Dev Technol. 2012 Jun;10(3):289-95. doi: 10.1089/adt.2011.0402. Epub 2011 Dec 22.


Dual antitumour effect of 5-azacytidine by inducing a breakdown of resistance-mediating factors and epigenetic modulation.

Venturelli S, Berger A, Weiland T, Zimmermann M, Häcker S, Peter C, Wesselborg S, Königsrainer A, Weiss TS, Gregor M, Fulda S, Lauer UM, Bitzer M.

Gut. 2011 Feb;60(2):156-65. doi: 10.1136/gut.2010.208041. Epub 2010 Nov 23.


The farnesyl transferase inhibitor lonafarnib inhibits mTOR signaling and enforces sorafenib-induced apoptosis in melanoma cells.

Niessner H, Beck D, Sinnberg T, Lasithiotakis K, Maczey E, Gogel J, Venturelli S, Berger A, Mauthe M, Toulany M, Flaherty K, Schaller M, Schadendorf D, Proikas-Cezanne T, Schittek B, Garbe C, Kulms D, Meier F.

J Invest Dermatol. 2011 Feb;131(2):468-79. doi: 10.1038/jid.2010.297. Epub 2010 Oct 14.


Epigenetic combination therapy as a tumor-selective treatment approach for hepatocellular carcinoma.

Venturelli S, Armeanu S, Pathil A, Hsieh CJ, Weiss TS, Vonthein R, Wehrmann M, Gregor M, Lauer UM, Bitzer M.

Cancer. 2007 May 15;109(10):2132-41.


HDAC inhibitor treatment of hepatoma cells induces both TRAIL-independent apoptosis and restoration of sensitivity to TRAIL.

Pathil A, Armeanu S, Venturelli S, Mascagni P, Weiss TS, Gregor M, Lauer UM, Bitzer M.

Hepatology. 2006 Mar;43(3):425-34.


Natural killer cell-mediated lysis of hepatoma cells via specific induction of NKG2D ligands by the histone deacetylase inhibitor sodium valproate.

Armeanu S, Bitzer M, Lauer UM, Venturelli S, Pathil A, Krusch M, Kaiser S, Jobst J, Smirnow I, Wagner A, Steinle A, Salih HR.

Cancer Res. 2005 Jul 15;65(14):6321-9.


Apoptosis on hepatoma cells but not on primary hepatocytes by histone deacetylase inhibitors valproate and ITF2357.

Armeanu S, Pathil A, Venturelli S, Mascagni P, Weiss TS, Göttlicher M, Gregor M, Lauer UM, Bitzer M.

J Hepatol. 2005 Feb;42(2):210-7.


Selective virus resistance conferred by expression of Borna disease virus nucleocapsid components.

Geib T, Sauder C, Venturelli S, Hässler C, Staeheli P, Schwemmle M.

J Virol. 2003 Apr;77(7):4283-90.


[Importance of Streptococci and in particular of the Enterococci in urinary tract infections].

Savarino A, Prattichizzo FA, Mattei R, Venturelli S.

Quad Sclavo Diagn. 1987 Sep;23(3):312-7. Italian.


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