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Items: 46

1.

Glucagon-like peptide 1 receptor agonists, diabetic retinopathy and angiogenesis: The AngioSafe type 2 diabetes study.

Gaborit B, Julla JB, Besbes S, Proust M, Vincentelli C, Alos B, Ancel P, Alzaid F, Garcia R, Mailly P, Sabatier F, Righini M, Gascon P, Matonti F, Houssays M, Goumidi L, Vignaud L, Guillonneau X, Erginay A, Dupas B, Jennifer ML, Autié M, Vidal-Trecan T, Riveline JP, Venteclef N, Massin P, Muller L, Dutour A, Gautier JF, Germain S.

J Clin Endocrinol Metab. 2019 Oct 7. pii: dgz069. doi: 10.1210/clinem/dgz069. [Epub ahead of print]

PMID:
31589290
2.

Plasma Copeptin and Risk of Lower-Extremity Amputation in Type 1 and Type 2 Diabetes.

Potier L, Roussel R, Marre M, Bjornstad P, Cherney DZ, El Boustany R, Fumeron F, Venteclef N, Gautier JF, Hadjadj S, Mohammedi K, Velho G.

Diabetes Care. 2019 Oct 3. pii: dc191062. doi: 10.2337/dc19-1062. [Epub ahead of print]

PMID:
31582427
3.

Transcriptional control of macrophage polarisation in type 2 diabetes.

Drareni K, Gautier JF, Venteclef N, Alzaid F.

Semin Immunopathol. 2019 Jul;41(4):515-529. doi: 10.1007/s00281-019-00748-1. Epub 2019 May 2. Review.

PMID:
31049647
4.

Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα.

Liang N, Damdimopoulos A, Goñi S, Huang Z, Vedin LL, Jakobsson T, Giudici M, Ahmed O, Pedrelli M, Barilla S, Alzaid F, Mendoza A, Schröder T, Kuiper R, Parini P, Hollenberg A, Lefebvre P, Francque S, Van Gaal L, Staels B, Venteclef N, Treuter E, Fan R.

Nat Commun. 2019 Apr 11;10(1):1684. doi: 10.1038/s41467-019-09524-z.

5.

Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment.

Brial F, Le Lay A, Hedjazi L, Tsang T, Fearnside JF, Otto GW, Alzaid F, Wilder SP, Venteclef N, Cazier JB, Nicholson JK, Day C, Burt AD, Gut IG, Lathrop M, Dumas ME, Gauguier D.

Sci Rep. 2019 Mar 6;9(1):3656. doi: 10.1038/s41598-019-40153-0.

6.

Isolation and Analysis of Human Monocytes and Adipose Tissue Macrophages.

Julla JB, Ballaire R, Ejlalmanesh T, Gautier JF, Venteclef N, Alzaid F.

Methods Mol Biol. 2019;1951:33-48. doi: 10.1007/978-1-4939-9130-3_3.

PMID:
30825142
7.

Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance.

Gilleron J, Bouget G, Ivanov S, Meziat C, Ceppo F, Vergoni B, Djedaini M, Soprani A, Dumas K, Jacquel A, Yvan-Charvet L, Venteclef N, Tanti JF, Cormont M.

Cell Rep. 2018 Dec 18;25(12):3329-3341.e5. doi: 10.1016/j.celrep.2018.11.083.

8.

GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation.

Drareni K, Ballaire R, Barilla S, Mathew MJ, Toubal A, Fan R, Liang N, Chollet C, Huang Z, Kondili M, Foufelle F, Soprani A, Roussel R, Gautier JF, Alzaid F, Treuter E, Venteclef N.

Cell Rep. 2018 Sep 11;24(11):2957-2971.e6. doi: 10.1016/j.celrep.2018.08.032.

9.

Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health.

Laurans L, Venteclef N, Haddad Y, Chajadine M, Alzaid F, Metghalchi S, Sovran B, Denis RGP, Dairou J, Cardellini M, Moreno-Navarrete JM, Straub M, Jegou S, McQuitty C, Viel T, Esposito B, Tavitian B, Callebert J, Luquet SH, Federici M, Fernandez-Real JM, Burcelin R, Launay JM, Tedgui A, Mallat Z, Sokol H, Taleb S.

Nat Med. 2018 Aug;24(8):1113-1120. doi: 10.1038/s41591-018-0060-4. Epub 2018 Jun 25.

PMID:
29942089
10.

Functional and phenotypical analysis of IL-6-secreting CD4+ T cells in human adipose tissue.

de Jong AJ, Pollastro S, Kwekkeboom JC, Andersen SN, Dorjée AL, Bakker AM, Alzaid F, Soprani A, Nelissen RGHH, Mullers JB, Venteclef N, de Vries N, Kloppenburg M, Toes REM, Ioan-Facsinay A.

Eur J Immunol. 2018 Mar;48(3):471-481. doi: 10.1002/eji.201747037. Epub 2018 Jan 29.

11.

The RBM14/CoAA-interacting, long intergenic non-coding RNA Paral1 regulates adipogenesis and coactivates the nuclear receptor PPARγ.

Firmin FF, Oger F, Gheeraert C, Dubois-Chevalier J, Vercoutter-Edouart AS, Alzaid F, Mazuy C, Dehondt H, Alexandre J, Derudas B, Dhalluin Q, Ploton M, Berthier A, Woitrain E, Lefebvre T, Venteclef N, Pattou F, Staels B, Eeckhoute J, Lefebvre P.

Sci Rep. 2017 Oct 26;7(1):14087. doi: 10.1038/s41598-017-14570-y.

12.

Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes.

Szpigel A, Hainault I, Carlier A, Venteclef N, Batto AF, Hajduch E, Bernard C, Ktorza A, Gautier JF, Ferré P, Bourron O, Foufelle F.

Diabetologia. 2018 Feb;61(2):399-412. doi: 10.1007/s00125-017-4462-5. Epub 2017 Oct 7.

PMID:
28988346
13.

Transcriptional repression in macrophages-basic mechanisms and alterations in metabolic inflammatory diseases.

Treuter E, Fan R, Huang Z, Jakobsson T, Venteclef N.

FEBS Lett. 2017 Oct;591(19):2959-2977. doi: 10.1002/1873-3468.12850. Epub 2017 Sep 25. Review.

14.

IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans.

Alzaid F, Lagadec F, Albuquerque M, Ballaire R, Orliaguet L, Hainault I, Blugeon C, Lemoine S, Lehuen A, Saliba DG, Udalova IA, Paradis V, Foufelle F, Venteclef N.

JCI Insight. 2016 Dec 8;1(20):e88689. doi: 10.1172/jci.insight.88689.

15.

Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes.

Fan R, Toubal A, Goñi S, Drareni K, Huang Z, Alzaid F, Ballaire R, Ancel P, Liang N, Damdimopoulos A, Hainault I, Soprani A, Aron-Wisnewsky J, Foufelle F, Lawrence T, Gautier JF, Venteclef N, Treuter E.

Nat Med. 2016 Jul;22(7):780-91. doi: 10.1038/nm.4114. Epub 2016 Jun 6.

PMID:
27270589
16.

[The adipose tissue macrophages: new modulators of fat mass repartition in obesity].

Dalmas É, Venteclef N.

Med Sci (Paris). 2015 Dec;31(12):1080-2. doi: 10.1051/medsci/20153112004. Epub 2015 Dec 16. French. No abstract available.

17.

Human epicardial adipose tissue has a specific transcriptomic signature depending on its anatomical peri-atrial, peri-ventricular, or peri-coronary location.

Gaborit B, Venteclef N, Ancel P, Pelloux V, Gariboldi V, Leprince P, Amour J, Hatem SN, Jouve E, Dutour A, Clément K.

Cardiovasc Res. 2015 Oct 1;108(1):62-73. doi: 10.1093/cvr/cvv208. Epub 2015 Aug 3.

PMID:
26239655
18.

Adipocyte Mineralocorticoid Receptor Activation Leads to Metabolic Syndrome and Induction of Prostaglandin D2 Synthase.

Urbanet R, Nguyen Dinh Cat A, Feraco A, Venteclef N, El Mogrhabi S, Sierra-Ramos C, Alvarez de la Rosa D, Adler GK, Quilliot D, Rossignol P, Fallo F, Touyz RM, Jaisser F.

Hypertension. 2015 Jul;66(1):149-57. doi: 10.1161/HYPERTENSIONAHA.114.04981. Epub 2015 May 11.

PMID:
25966493
19.

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.

Dalmas E, Toubal A, Alzaid F, Blazek K, Eames HL, Lebozec K, Pini M, Hainault I, Montastier E, Denis RG, Ancel P, Lacombe A, Ling Y, Allatif O, Cruciani-Guglielmacci C, André S, Viguerie N, Poitou C, Stich V, Torcivia A, Foufelle F, Luquet S, Aron-Wisnewsky J, Langin D, Clément K, Udalova IA, Venteclef N.

Nat Med. 2015 Jun;21(6):610-8. doi: 10.1038/nm.3829. Epub 2015 May 4.

PMID:
25939064
20.

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients.

Magalhaes I, Pingris K, Poitou C, Bessoles S, Venteclef N, Kiaf B, Beaudoin L, Da Silva J, Allatif O, Rossjohn J, Kjer-Nielsen L, McCluskey J, Ledoux S, Genser L, Torcivia A, Soudais C, Lantz O, Boitard C, Aron-Wisnewsky J, Larger E, Clément K, Lehuen A.

J Clin Invest. 2015 Apr;125(4):1752-62. doi: 10.1172/JCI78941. Epub 2015 Mar 9.

21.

Adipocyte ATP-binding cassette G1 promotes triglyceride storage, fat mass growth, and human obesity.

Frisdal E, Le Lay S, Hooton H, Poupel L, Olivier M, Alili R, Plengpanich W, Villard EF, Gilibert S, Lhomme M, Superville A, Miftah-Alkhair L, Chapman MJ, Dallinga-Thie GM, Venteclef N, Poitou C, Tordjman J, Lesnik P, Kontush A, Huby T, Dugail I, Clement K, Guerin M, Le Goff W.

Diabetes. 2015 Mar;64(3):840-55. doi: 10.2337/db14-0245. Epub 2014 Sep 23.

22.

Cathepsin S inhibition lowers blood glucose levels in mice.

Lafarge JC, Pini M, Pelloux V, Orasanu G, Hartmann G, Venteclef N, Sulpice T, Shi GP, Clément K, Guerre-Millo M.

Diabetologia. 2014 Aug;57(8):1674-83. doi: 10.1007/s00125-014-3280-2. Epub 2014 Jun 3.

PMID:
24891017
23.

The oxysterol receptor LXRβ protects against DSS- and TNBS-induced colitis in mice.

Jakobsson T, Vedin LL, Hassan T, Venteclef N, Greco D, D'Amato M, Treuter E, Gustafsson JÅ, Steffensen KR.

Mucosal Immunol. 2014 Nov;7(6):1416-28. doi: 10.1038/mi.2014.31. Epub 2014 May 7.

PMID:
24803164
24.

Liver X receptor: from metabolism to cancer.

Venteclef N, Ferré P.

Biochem J. 2014 Apr 15;459(2):e1-3. doi: 10.1042/BJ20140211.

PMID:
24678940
25.

Adaptive expression of microRNA-125a in adipose tissue in response to obesity in mice and men.

Diawara MR, Hue C, Wilder SP, Venteclef N, Aron-Wisnewsky J, Scott J, Clément K, Gauguier D, Calderari S.

PLoS One. 2014 Mar 27;9(3):e91375. doi: 10.1371/journal.pone.0091375. eCollection 2014.

26.

T cell-derived IL-22 amplifies IL-1β-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes.

Dalmas E, Venteclef N, Caer C, Poitou C, Cremer I, Aron-Wisnewsky J, Lacroix-Desmazes S, Bayry J, Kaveri SV, Clément K, André S, Guerre-Millo M.

Diabetes. 2014 Jun;63(6):1966-77. doi: 10.2337/db13-1511. Epub 2014 Feb 11.

27.

[An « inflamed » relationship between GPS2 and the adipose tissue in human obesity].

Toubal A, Treuter E, Venteclef N.

Med Sci (Paris). 2014 Jan;30(1):15-8. doi: 10.1051/medsci/20143001004. Epub 2014 Jan 24. French. No abstract available.

28.

Genomic and epigenomic regulation of adipose tissue inflammation in obesity.

Toubal A, Treuter E, Clément K, Venteclef N.

Trends Endocrinol Metab. 2013 Dec;24(12):625-34. doi: 10.1016/j.tem.2013.09.006. Epub 2013 Oct 27. Review.

PMID:
24169451
29.

Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines.

Venteclef N, Guglielmi V, Balse E, Gaborit B, Cotillard A, Atassi F, Amour J, Leprince P, Dutour A, Clément K, Hatem SN.

Eur Heart J. 2015 Apr 1;36(13):795-805a. doi: 10.1093/eurheartj/eht099. Epub 2013 Mar 22.

PMID:
23525094
30.

Fetal PGC-1α overexpression programs adult pancreatic β-cell dysfunction.

Valtat B, Riveline JP, Zhang P, Singh-Estivalet A, Armanet M, Venteclef N, Besseiche A, Kelly DP, Tronche F, Ferré P, Gautier JF, Bréant B, Blondeau B.

Diabetes. 2013 Apr;62(4):1206-16. doi: 10.2337/db12-0314. Epub 2012 Dec 28.

31.

SMRT-GPS2 corepressor pathway dysregulation coincides with obesity-linked adipocyte inflammation.

Toubal A, Clément K, Fan R, Ancel P, Pelloux V, Rouault C, Veyrie N, Hartemann A, Treuter E, Venteclef N.

J Clin Invest. 2013 Jan;123(1):362-79. doi: 10.1172/JCI64052. Epub 2012 Dec 10.

32.

Fasting-induced FGF21 is repressed by LXR activation via recruitment of an HDAC3 corepressor complex in mice.

Archer A, Venteclef N, Mode A, Pedrelli M, Gabbi C, Clément K, Parini P, Gustafsson JÅ, Korach-André M.

Mol Endocrinol. 2012 Dec;26(12):1980-90. doi: 10.1210/me.2012-1151. Epub 2012 Oct 16.

33.

Valsartan improves adipose tissue function in humans with impaired glucose metabolism: a randomized placebo-controlled double-blind trial.

Goossens GH, Moors CC, van der Zijl NJ, Venteclef N, Alili R, Jocken JW, Essers Y, Cleutjens JP, Clément K, Diamant M, Blaak EE.

PLoS One. 2012;7(6):e39930. doi: 10.1371/journal.pone.0039930. Epub 2012 Jun 29.

34.

Krüppel-like factor 4 regulates macrophage polarization.

Liao X, Sharma N, Kapadia F, Zhou G, Lu Y, Hong H, Paruchuri K, Mahabeleshwar GH, Dalmas E, Venteclef N, Flask CA, Kim J, Doreian BW, Lu KQ, Kaestner KH, Hamik A, Clément K, Jain MK.

J Clin Invest. 2011 Jul;121(7):2736-49. doi: 10.1172/JCI45444. Epub 2011 Jun 13.

35.

Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation.

Goossens GH, Bizzarri A, Venteclef N, Essers Y, Cleutjens JP, Konings E, Jocken JW, Cajlakovic M, Ribitsch V, Clément K, Blaak EE.

Circulation. 2011 Jul 5;124(1):67-76. doi: 10.1161/CIRCULATIONAHA.111.027813. Epub 2011 Jun 13.

PMID:
21670228
36.

Metabolic nuclear receptor signaling and the inflammatory acute phase response.

Venteclef N, Jakobsson T, Steffensen KR, Treuter E.

Trends Endocrinol Metab. 2011 Aug;22(8):333-43. doi: 10.1016/j.tem.2011.04.004. Epub 2011 Jun 7. Review.

PMID:
21646028
37.

Transcriptional control of metabolic and inflammatory pathways by nuclear receptor SUMOylation.

Treuter E, Venteclef N.

Biochim Biophys Acta. 2011 Aug;1812(8):909-18. doi: 10.1016/j.bbadis.2010.12.008. Epub 2010 Dec 21. Review.

38.

Liver X receptor (LXR) regulates human adipocyte lipolysis.

Stenson BM, Rydén M, Venteclef N, Dahlman I, Pettersson AM, Mairal A, Aström G, Blomqvist L, Wang V, Jocken JW, Clément K, Langin D, Arner P, Laurencikiene J.

J Biol Chem. 2011 Jan 7;286(1):370-9. doi: 10.1074/jbc.M110.179499. Epub 2010 Oct 28.

39.

GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response.

Venteclef N, Jakobsson T, Ehrlund A, Damdimopoulos A, Mikkonen L, Ellis E, Nilsson LM, Parini P, Jänne OA, Gustafsson JA, Steffensen KR, Treuter E.

Genes Dev. 2010 Feb 15;24(4):381-95. doi: 10.1101/gad.545110.

40.

The human ADFP gene is a direct liver-X-receptor (LXR) target gene and differentially regulated by synthetic LXR ligands.

Kotokorpi P, Venteclef N, Ellis E, Gustafsson JA, Mode A.

Mol Pharmacol. 2010 Jan;77(1):79-86. doi: 10.1124/mol.109.059063. Epub 2009 Oct 20.

PMID:
19843633
41.

GPS2 is required for cholesterol efflux by triggering histone demethylation, LXR recruitment, and coregulator assembly at the ABCG1 locus.

Jakobsson T, Venteclef N, Toresson G, Damdimopoulos AE, Ehrlund A, Lou X, Sanyal S, Steffensen KR, Gustafsson JA, Treuter E.

Mol Cell. 2009 May 14;34(4):510-8. doi: 10.1016/j.molcel.2009.05.006.

42.

E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesis.

Ehrlund A, Anthonisen EH, Gustafsson N, Venteclef N, Robertson Remen K, Damdimopoulos AE, Galeeva A, Pelto-Huikko M, Lalli E, Steffensen KR, Gustafsson JA, Treuter E.

Mol Cell Biol. 2009 Apr;29(8):2230-42. doi: 10.1128/MCB.00743-08. Epub 2009 Feb 23.

43.

Regulation of anti-atherogenic apolipoprotein M gene expression by the orphan nuclear receptor LRH-1.

Venteclef N, Haroniti A, Tousaint JJ, Talianidis I, Delerive P.

J Biol Chem. 2008 Feb 15;283(7):3694-701. Epub 2007 Oct 31.

45.

Liver receptor homolog 1 is a negative regulator of the hepatic acute-phase response.

Venteclef N, Smith JC, Goodwin B, Delerive P.

Mol Cell Biol. 2006 Sep;26(18):6799-807.

46.

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