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Items: 1 to 50 of 145

1.

Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area.

Harder L, Dudazy-Gralla S, Müller-Fielitz H, Hjerling Leffler J, Vennström B, Heuer H, Mittag J.

J Neuroendocrinol. 2018 Mar;30(3):e12573. doi: 10.1111/jne.12573.

PMID:
29377458
2.

Thermoregulatory and Cardiovascular Consequences of a Transient Thyrotoxicosis and Recovery in Male Mice.

Hoefig CS, Harder L, Oelkrug R, Meusel M, Vennström B, Brabant G, Mittag J.

Endocrinology. 2016 Jul;157(7):2957-67. doi: 10.1210/en.2016-1095. Epub 2016 May 4.

PMID:
27145010
3.

Thyroid hormone drives the expression of mouse carbonic anhydrase Car4 in kidney, lung and brain.

Vujovic M, Dudazy-Gralla S, Hård J, Solsjö P, Warner A, Vennström B, Mittag J.

Mol Cell Endocrinol. 2015 Nov 15;416:19-26. doi: 10.1016/j.mce.2015.08.017. Epub 2015 Aug 28.

PMID:
26319697
4.

3-Iodothyroacetic acid lacks thermoregulatory and cardiovascular effects in vivo.

Hoefig CS, Jacobi SF, Warner A, Harder L, Schanze N, Vennström B, Mittag J.

Br J Pharmacol. 2015 Jul;172(13):3426-33. doi: 10.1111/bph.13131. Epub 2015 Jun 9.

5.

Inappropriate heat dissipation ignites brown fat thermogenesis in mice with a mutant thyroid hormone receptor α1.

Warner A, Rahman A, Solsjö P, Gottschling K, Davis B, Vennström B, Arner A, Mittag J.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16241-6. doi: 10.1073/pnas.1310300110. Epub 2013 Sep 17.

6.

Identification of thyroid hormone response elements in vivo using mice expressing a tagged thyroid hormone receptor α1.

Dudazy-Gralla S, Nordström K, Hofmann PJ, Meseh DA, Schomburg L, Vennström B, Mittag J.

Biosci Rep. 2013 Mar 13;33(2):e00027. doi: 10.1042/BSR20120124.

7.

Thyroid hormone is required for hypothalamic neurons regulating cardiovascular functions.

Mittag J, Lyons DJ, Sällström J, Vujovic M, Dudazy-Gralla S, Warner A, Wallis K, Alkemade A, Nordström K, Monyer H, Broberger C, Arner A, Vennström B.

J Clin Invest. 2013 Jan;123(1):509-16. doi: 10.1172/JCI65252. Epub 2012 Dec 21.

8.

Serum copper as a novel biomarker for resistance to thyroid hormone.

Mittag J, Behrends T, Nordström K, Anselmo J, Vennström B, Schomburg L.

Biochem J. 2012 Apr 1;443(1):103-9. doi: 10.1042/BJ20111817.

PMID:
22220593
9.

Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene.

Pazirandeh A, Sultana T, Mirza M, Rozell B, Hultenby K, Wallis K, Vennström B, Davis B, Arner A, Heuchel R, Löhr M, Philipson L, Sollerbrant K.

PLoS One. 2011;6(6):e20203. doi: 10.1371/journal.pone.0020203. Epub 2011 Jun 3.

10.

Loss of thyroid hormone receptor β is associated with increased progenitor proliferation and NeuroD positive cell number in the adult hippocampus.

Kapoor R, Ghosh H, Nordstrom K, Vennstrom B, Vaidya VA.

Neurosci Lett. 2011 Jan 7;487(2):199-203. doi: 10.1016/j.neulet.2010.10.022. Epub 2010 Oct 17.

11.

Thyroid hormones regulate selenoprotein expression and selenium status in mice.

Mittag J, Behrends T, Hoefig CS, Vennström B, Schomburg L.

PLoS One. 2010 Sep 22;5(9):e12931. doi: 10.1371/journal.pone.0012931.

12.

The thyroid hormone receptor alpha1 protein is expressed in embryonic postmitotic neurons and persists in most adult neurons.

Wallis K, Dudazy S, van Hogerlinden M, Nordström K, Mittag J, Vennström B.

Mol Endocrinol. 2010 Oct;24(10):1904-16. doi: 10.1210/me.2010-0175. Epub 2010 Aug 25.

13.

Unliganded thyroid hormone receptor alpha1 impairs adult hippocampal neurogenesis.

Kapoor R, van Hogerlinden M, Wallis K, Ghosh H, Nordstrom K, Vennstrom B, Vaidya VA.

FASEB J. 2010 Dec;24(12):4793-805. doi: 10.1096/fj.10-161802. Epub 2010 Aug 13.

14.

Enlarged lateral ventricles and aberrant behavior in mice overexpressing PDGF-B in embryonic neural stem cells.

Niklasson M, Bergström T, Zhang XQ, Gustafsdottir SM, Sjögren M, Edqvist PH, Vennström B, Forsberg M, Forsberg-Nilsson K.

Exp Cell Res. 2010 Oct 15;316(17):2779-89. doi: 10.1016/j.yexcr.2010.07.009. Epub 2010 Jul 17.

PMID:
20643125
15.

Increased depressive behaviour in mice harboring the mutant thyroid hormone receptor alpha 1.

Pilhatsch M, Winter C, Nordström K, Vennström B, Bauer M, Juckel G.

Behav Brain Res. 2010 Dec 25;214(2):187-92. doi: 10.1016/j.bbr.2010.05.016. Epub 2010 May 16.

PMID:
20580649
16.

Adaptations of the autonomous nervous system controlling heart rate are impaired by a mutant thyroid hormone receptor-alpha1.

Mittag J, Davis B, Vujovic M, Arner A, Vennström B.

Endocrinology. 2010 May;151(5):2388-95. doi: 10.1210/en.2009-1201. Epub 2010 Mar 12.

PMID:
20228172
17.

A mutant thyroid hormone receptor alpha1 alters hippocampal circuitry and reduces seizure susceptibility in mice.

Hadjab-Lallemend S, Wallis K, van Hogerlinden M, Dudazy S, Nordström K, Vennström B, Fisahn A.

Neuropharmacology. 2010 Jun;58(7):1130-9. doi: 10.1016/j.neuropharm.2010.02.005. Epub 2010 Feb 12.

PMID:
20153760
18.

Thyroid hormone receptor alpha can control action potential duration in mouse ventricular myocytes through the KCNE1 ion channel subunit.

Mansén A, Tiselius C, Sand P, Fauconnier J, Westerblad H, Rydqvist B, Vennström B.

Acta Physiol (Oxf). 2010 Feb;198(2):133-42. doi: 10.1111/j.1748-1716.2009.02052.x. Epub 2009 Oct 14.

PMID:
19832729
19.

Interference of a mutant thyroid hormone receptor alpha1 with hepatic glucose metabolism.

Vujovic M, Nordström K, Gauthier K, Flamant F, Visser TJ, Vennström B, Mittag J.

Endocrinology. 2009 Jun;150(6):2940-7. doi: 10.1210/en.2008-1085. Epub 2009 Mar 12.

PMID:
19282388
20.

Thyroid hormone receptor beta1 acts as a potent suppressor of tumor invasiveness and metastasis.

Martínez-Iglesias O, Garcia-Silva S, Tenbaum SP, Regadera J, Larcher F, Paramio JM, Vennström B, Aranda A.

Cancer Res. 2009 Jan 15;69(2):501-9. doi: 10.1158/0008-5472.CAN-08-2198.

21.

Physiological consequences of the TRalpha1 aporeceptor state.

Mittag J, Wallis K, Vennström B.

Heart Fail Rev. 2010 Mar;15(2):111-5. doi: 10.1007/s10741-008-9119-5. Epub 2008 Nov 14. Review.

PMID:
19009345
22.

Severe psychomotor and metabolic damages caused by a mutant thyroid hormone receptor alpha 1 in mice: can patients with a similar mutation be found and treated?

Vennström B, Mittag J, Wallis K.

Acta Paediatr. 2008 Dec;97(12):1605-10. doi: 10.1111/j.1651-2227.2008.01031.x. Epub 2008 Sep 15. Review.

PMID:
18795907
23.

Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha.

Duez H, van der Veen JN, Duhem C, Pourcet B, Touvier T, Fontaine C, Derudas B, Baugé E, Havinga R, Bloks VW, Wolters H, van der Sluijs FH, Vennström B, Kuipers F, Staels B.

Gastroenterology. 2008 Aug;135(2):689-98. doi: 10.1053/j.gastro.2008.05.035. Epub 2008 May 15.

PMID:
18565334
24.

Locomotor deficiencies and aberrant development of subtype-specific GABAergic interneurons caused by an unliganded thyroid hormone receptor alpha1.

Wallis K, Sjögren M, van Hogerlinden M, Silberberg G, Fisahn A, Nordström K, Larsson L, Westerblad H, Morreale de Escobar G, Shupliakov O, Vennström B.

J Neurosci. 2008 Feb 20;28(8):1904-15. doi: 10.1523/JNEUROSCI.5163-07.2008.

25.

Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor alpha1.

Sjögren M, Alkemade A, Mittag J, Nordström K, Katz A, Rozell B, Westerblad H, Arner A, Vennström B.

EMBO J. 2007 Oct 31;26(21):4535-45. Epub 2007 Oct 11.

26.

Thyroid status during skeletal development determines adult bone structure and mineralization.

Bassett JH, Nordström K, Boyde A, Howell PG, Kelly S, Vennström B, Williams GR.

Mol Endocrinol. 2007 Aug;21(8):1893-904. Epub 2007 May 8.

PMID:
17488972
27.

International Union of Pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: thyroid hormone receptors.

Flamant F, Baxter JD, Forrest D, Refetoff S, Samuels H, Scanlan TS, Vennström B, Samarut J.

Pharmacol Rev. 2006 Dec;58(4):705-11. Review. No abstract available.

PMID:
17132849
28.

Analysis of skeletal phenotypes in thyroid hormone receptor mutant mice.

Bassett JH, O'Shea PJ, Chassande O, Samarut J, Cheng SY, Vennstrom B, Howell PG, Boyde A, Williams GR.

Scanning. 2006 Apr 1;28(2):91-93. No abstract available.

29.

Anxiety, memory impairment, and locomotor dysfunction caused by a mutant thyroid hormone receptor alpha1 can be ameliorated by T3 treatment.

Venero C, Guadaño-Ferraz A, Herrero AI, Nordström K, Manzano J, de Escobar GM, Bernal J, Vennström B.

Genes Dev. 2005 Sep 15;19(18):2152-63. Epub 2005 Aug 30.

30.

Impaired Ca2+ handling and contraction in cardiomyocytes from mice with a dominant negative thyroid hormone receptor alpha1.

Tavi P, Sjögren M, Lunde PK, Zhang SJ, Abbate F, Vennström B, Westerblad H.

J Mol Cell Cardiol. 2005 Apr;38(4):655-63.

PMID:
15808842
31.

Retinoid-related receptor (ROR) alpha mRNA expression is altered in the brain of male mice lacking all ligand-binding thyroid hormone receptor (TR) isoforms.

Vasudevan N, Kia HK, Hadjimarkou M, Koibuchi N, Chin WW, Forrest D, Vennstrom B, Pfaff D.

Endocrine. 2005 Feb;26(1):25-32.

PMID:
15805582
32.

Increased adipogenesis in bone marrow but decreased bone mineral density in mice devoid of thyroid hormone receptors.

Kindblom JM, Gevers EF, Skrtic SM, Lindberg MK, Göthe S, Törnell J, Vennström B, Ohlsson C.

Bone. 2005 Apr;36(4):607-16.

PMID:
15780976
33.

Thyroid hormone receptor expression in the human hypothalamus and anterior pituitary.

Alkemade A, Vuijst CL, Unmehopa UA, Bakker O, Vennström B, Wiersinga WM, Swaab DF, Fliers E.

J Clin Endocrinol Metab. 2005 Feb;90(2):904-12. Epub 2004 Nov 23.

PMID:
15562027
34.

Aberrant expression of myosin isoforms in skeletal muscles from mice lacking the rev-erbAalpha orphan receptor gene.

Pircher P, Chomez P, Yu F, Vennström B, Larsson L.

Am J Physiol Regul Integr Comp Physiol. 2005 Feb;288(2):R482-90. Epub 2004 Sep 16.

35.

Zonal expression of the thyroid hormone receptor alpha isoforms in rodent liver.

Zandieh-Doulabi B, Dop E, Schneiders M, Schiphorst MP, Mansen A, Vennström B, Dijkstra CD, Bakker O, Wiersinga WM.

J Endocrinol. 2003 Dec;179(3):379-85.

PMID:
14656207
36.

Depressed thermogenesis but competent brown adipose tissue recruitment in mice devoid of all hormone-binding thyroid hormone receptors.

Golozoubova V, Gullberg H, Matthias A, Cannon B, Vennström B, Nedergaard J.

Mol Endocrinol. 2004 Feb;18(2):384-401. Epub 2003 Nov 20.

PMID:
14630998
37.

Aberrant maturation of astrocytes in thyroid hormone receptor alpha 1 knockout mice reveals an interplay between thyroid hormone receptor isoforms.

Morte B, Manzano J, Scanlan TS, Vennström B, Bernal J.

Endocrinology. 2004 Mar;145(3):1386-91. Epub 2003 Nov 20.

38.

Selective thyroid hormone receptor-beta activation: a strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability.

Grover GJ, Mellström K, Ye L, Malm J, Li YL, Bladh LG, Sleph PG, Smith MA, George R, Vennström B, Mookhtiar K, Horvath R, Speelman J, Egan D, Baxter JD.

Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):10067-72. Epub 2003 Jul 29.

39.
40.

Lack of thyroid hormone receptor alpha1 is associated with selective alterations in behavior and hippocampal circuits.

Guadaño-Ferraz A, Benavides-Piccione R, Venero C, Lancha C, Vennström B, Sandi C, DeFelipe J, Bernal J.

Mol Psychiatry. 2003 Jan;8(1):30-8.

PMID:
12556906
41.

Normal timing of oligodendrocyte development depends on thyroid hormone receptor alpha 1 (TRalpha1).

Billon N, Jolicoeur C, Tokumoto Y, Vennström B, Raff M.

EMBO J. 2002 Dec 2;21(23):6452-60.

42.

Identification of Rev-erbalpha as a physiological repressor of apoC-III gene transcription.

Raspé E, Duez H, Mansén A, Fontaine C, Fiévet C, Fruchart JC, Vennström B, Staels B.

J Lipid Res. 2002 Dec;43(12):2172-9.

43.

Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1.

Tinnikov A, Nordström K, Thorén P, Kindblom JM, Malin S, Rozell B, Adams M, Rajanayagam O, Pettersson S, Ohlsson C, Chatterjee K, Vennström B.

EMBO J. 2002 Oct 1;21(19):5079-87.

44.

Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice.

Gullberg H, Rudling M, Saltó C, Forrest D, Angelin B, Vennström B.

Mol Endocrinol. 2002 Aug;16(8):1767-77.

PMID:
12145333
45.

Patterns of liver gene expression governed by TRbeta.

Flores-Morales A, Gullberg H, Fernandez L, Ståhlberg N, Lee NH, Vennström B, Norstedt G.

Mol Endocrinol. 2002 Jun;16(6):1257-68.

PMID:
12040013
46.

Deletion of the thyroid hormone receptor alpha 1 prevents the structural alterations of the cerebellum induced by hypothyroidism.

Morte B, Manzano J, Scanlan T, Vennström B, Bernal J.

Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3985-9. Epub 2002 Mar 12.

47.

Accelerated inactivation of voltage-dependent K+ outward current in cardiomyocytes from thyroid hormone receptor alpha1-deficient mice.

Johansson C, Koopmann R, Vennström B, Benndorf K.

J Cardiovasc Electrophysiol. 2002 Jan;13(1):44-50.

PMID:
11843482
48.

Retardation of cochlear maturation and impaired hair cell function caused by deletion of all known thyroid hormone receptors.

Rusch A, Ng L, Goodyear R, Oliver D, Lisoukov I, Vennstrom B, Richardson G, Kelley MW, Forrest D.

J Neurosci. 2001 Dec 15;21(24):9792-800.

49.

Ablation of TRalpha2 and a concomitant overexpression of alpha1 yields a mixed hypo- and hyperthyroid phenotype in mice.

Saltó C, Kindblom JM, Johansson C, Wang Z, Gullberg H, Nordström K, Mansén A, Ohlsson C, Thorén P, Forrest D, Vennström B.

Mol Endocrinol. 2001 Dec;15(12):2115-28.

PMID:
11731613
50.

TRs have common and isoform-specific functions in regulation of the cardiac myosin heavy chain genes.

Mansén A, Yu F, Forrest D, Larsson L, Vennström B.

Mol Endocrinol. 2001 Dec;15(12):2106-14.

PMID:
11731612

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