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Dapagliflozin for prednisone-induced hyperglycaemia in acute exacerbation of chronic obstructive pulmonary disease.
Gerards MC, Venema GE, Patberg KW, Kross M, Potter van Loon BJ, Hageman IMG, Snijders D, Brandjes DPM, Hoekstra JBL, Vriesendorp TM, Gerdes VEA.
Diabetes Obes Metab. 2018 May;20(5):1306-1310. doi: 10.1111/dom.13209. Epub 2018 Feb 6.
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The 48-hour tetrahydrobiopterin loading test in patients with phenylketonuria: evaluation of protocol and influence of baseline phenylalanine concentration.
Anjema K, Venema G, Hofstede FC, Carbasius Weber EC, Bosch AM, Ter Horst NM, Hollak CE, Jonkers CF, Rubio-Gozalbo ME, van der Ploeg EM, de Vries MC, Janssen-Regelink RG, Janssen MC, Zweers-van Essen H, Boelen CC, van der Herberg-van de Wetering NA, Heiner-Fokkema MR, van Rijn M, van Spronsen FJ.
Mol Genet Metab. 2011;104 Suppl:S60-3. doi: 10.1016/j.ymgme.2011.09.024. Epub 2011 Sep 23.
Heterologous Processing and Export of the Bacteriocins Pediocin PA-1 and Lactococcin A in Lactococcus Lactis: A Study with Leader Exchange.
Chikindas M, Emond E, Haandrikman AJ, Kok J, Leenhouts K, Pandian S, Venema G, Venema K.
Probiotics Antimicrob Proteins. 2010 Jun;2(2):66-76. doi: 10.1007/s12602-009-9023-x.
Reduced lysis upon growth of Lactococcus lactis on galactose is a consequence of decreased binding of the autolysin AcmA.
Steen A, Buist G, Kramer NE, Jalving R, Benus GF, Venema G, Kuipers OP, Kok J.
Appl Environ Microbiol. 2008 Aug;74(15):4671-9. doi: 10.1128/AEM.00103-08. Epub 2008 Jun 6.
Novel methods for genetic transformation of natural Bacillus subtilis isolates used to study the regulation of the mycosubtilin and surfactin synthetases.
Duitman EH, Wyczawski D, Boven LG, Venema G, Kuipers OP, Hamoen LW.
Appl Environ Microbiol. 2007 Jun;73(11):3490-6. Epub 2007 Apr 6.
Immunogenicity of a malaria parasite antigen displayed by Lactococcus lactis in oral immunisations.
Ramasamy R, Yasawardena S, Zomer A, Venema G, Kok J, Leenhouts K.
Vaccine. 2006 May 1;24(18):3900-8. Epub 2006 Mar 2.
Characterization of the lytic-lysogenic switch of the lactococcal bacteriophage Tuc2009.
Kenny JG, Leach S, de la Hoz AB, Venema G, Kok J, Fitzgerald GF, Nauta A, Alonso JC, van Sinderen D.
Virology. 2006 Apr 10;347(2):434-46. Epub 2006 Jan 10.
AcmA of Lactococcus lactis is an N-acetylglucosaminidase with an optimal number of LysM domains for proper functioning.
Steen A, Buist G, Horsburgh GJ, Venema G, Kuipers OP, Foster SJ, Kok J.
FEBS J. 2005 Jun;272(11):2854-68.
Mechanism of transcription activation at the comG promoter by the competence transcription factor ComK of Bacillus subtilis.
Susanna KA, van der Werff AF, den Hengst CD, Calles B, Salas M, Venema G, Hamoen LW, Kuipers OP.
J Bacteriol. 2004 Feb;186(4):1120-8.
Cell wall attachment of a widely distributed peptidoglycan binding domain is hindered by cell wall constituents.
Steen A, Buist G, Leenhouts KJ, El Khattabi M, Grijpstra F, Zomer AL, Venema G, Kuipers OP, Kok J.
J Biol Chem. 2003 Jun 27;278(26):23874-81. Epub 2003 Apr 8.
The Bacillus subtilis transition state regulator AbrB binds to the -35 promoter region of comK.
Hamoen LW, Kausche D, Marahiel MA, van Sinderen D, Venema G, Serror P.
FEMS Microbiol Lett. 2003 Jan 28;218(2):299-304.
Active lipoprotein precursors in the Gram-positive eubacterium Lactococcus lactis.
Venema R, Tjalsma H, van Dijl JM, de Jong A, Leenhouts K, Buist G, Venema G.
J Biol Chem. 2003 Apr 25;278(17):14739-46. Epub 2003 Feb 12.
Controlling competence in Bacillus subtilis: shared use of regulators.
Hamoen LW, Venema G, Kuipers OP.
Microbiology. 2003 Jan;149(Pt 1):9-17. Review.
Characterization of the putative replisome organizer of the lactococcal bacteriophage r1t.
Zúñiga M, Franke-Fayard B, Venema G, Kok J, Nauta A.
J Virol. 2002 Oct;76(20):10234-44.
The effects of modifying the surface charge on the catalytic activity of a thermolysin-like protease.
de Kreij A, van den Burg B, Venema G, Vriend G, Eijsink VG, Nielsen JE.
J Biol Chem. 2002 May 3;277(18):15432-8. Epub 2002 Feb 21.
Proteins of the lactococcin A secretion system: lcnD encodes two in-frame proteins.
Varcamonti M, Nicastro G, Venema G, Kok J.
FEMS Microbiol Lett. 2001 Nov 13;204(2):259-63.
The effect of changing the hydrophobic S1' subsite of thermolysin-like proteases on substrate specificity.
de Kreij A, van den Burg B, Veltman OR, Vriend G, Venema G, Eijsink VG.
Eur J Biochem. 2001 Sep;268(18):4985-91.
The Bacillus subtilis competence transcription factor, ComK, overrides LexA-imposed transcriptional inhibition without physically displacing LexA.
Hamoen LW, Haijema B, Bijlsma JJ, Venema G, Lovett CM.
J Biol Chem. 2001 Nov 16;276(46):42901-7. Epub 2001 Sep 12.
Regulation of bacteriocin production in Lactobacillus plantarum depends on a conserved promoter arrangement with consensus binding sequence.
Risøen PA, Johnsborg O, Diep DB, Hamoen L, Venema G, Nes IF.
Mol Genet Genomics. 2001 Mar;265(1):198-206.
Distinction between major and minor Bacillus signal peptidases based on phylogenetic and structural criteria.
van Roosmalen ML, Jongbloed JD, Dubois JY, Venema G, Bron S, van Dijl JM.
J Biol Chem. 2001 Jul 6;276(27):25230-5. Epub 2001 Apr 17.
Detergent-independent in vitro activity of a truncated Bacillus signal peptidase.
van Roosmalen ML, Jongbloed JDH, Jong A, van Eerden J, Venema G, Bron S, Maarten van Dijl J.
Microbiology. 2001 Apr;147(Pt 4):909-917. doi: 10.1099/00221287-147-4-909.
TatC is a specificity determinant for protein secretion via the twin-arginine translocation pathway.
Jongbloed JD, Martin U, Antelmann H, Hecker M, Tjalsma H, Venema G, Bron S, van Dijl JM, Müller J.
J Biol Chem. 2000 Dec 29;275(52):41350-7.
A truncated soluble Bacillus signal peptidase produced in Escherichia coli is subject to self-cleavage at its active site.
van Roosmalen ML, Jongbloed JD, Kuipers A, Venema G, Bron S, van DijL JM.
J Bacteriol. 2000 Oct;182(20):5765-70.
The pleiotropic response regulator DegU functions as a priming protein in competence development in Bacillus subtilis.
Hamoen LW, Van Werkhoven AF, Venema G, Dubnau D.
Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9246-51.
Substrate specificity in the highly heterogeneous M4 peptidase family is determined by a small subset of amino acids.
de Kreij A, Venema G, van den Burg B.
J Biol Chem. 2000 Oct 6;275(40):31115-20.
Expression of the neutral protease gene from a thermophilic Bacillus sp. BT1 strain in Bacillus subtilis and its natural host: identification of a functional promoter.
Vecerek B, Venema G.
J Bacteriol. 2000 Jul;182(14):4104-7.
Conserved serine and histidine residues are critical for activity of the ER-type signal peptidase SipW of Bacillus subtilis.
Tjalsma H, Stover AG, Driks A, Venema G, Bron S, van Dijl JM.
J Biol Chem. 2000 Aug 18;275(33):25102-8.
Did the mitochondrial processing peptidase evolve from a eubacterial regulator of gene expression?
Bolhuis A, Koetje E, Dubois JY, Vehmaanperä J, Venema G, Bron S, van Dijl JM.
Mol Biol Evol. 2000 Jan;17(1):198-201. No abstract available.
Chaperone-like activities of the CsaA protein of Bacillus subtilis.
Müller JP, Bron S, Venema G, Maarten van Dijl J.
Microbiology. 2000 Jan;146 ( Pt 1):77-88. doi: 10.1099/00221287-146-1-77.
The mycosubtilin synthetase of Bacillus subtilis ATCC6633: a multifunctional hybrid between a peptide synthetase, an amino transferase, and a fatty acid synthase.
Duitman EH, Hamoen LW, Rembold M, Venema G, Seitz H, Saenger W, Bernhard F, Reinhardt R, Schmidt M, Ullrich C, Stein T, Leenders F, Vater J.
Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13294-9.
From DNA sequence to application: possibilities and complications.
Venema G, Kok J, van Sinderen D.
Antonie Van Leeuwenhoek. 1999 Jul-Nov;76(1-4):3-23. Review.
The potential active site of the lipoprotein-specific (type II) signal peptidase of Bacillus subtilis.
Tjalsma H, Zanen G, Venema G, Bron S, van Dijl JM.
J Biol Chem. 1999 Oct 1;274(40):28191-7.
Characterization of a novel stable biocatalyst obtained by protein engineering.
Van den Burg B, de Kreij A, Van der Veek P, Mansfeld J, Venema G.
Biotechnol Appl Biochem. 1999 Aug;30(1):35-40.
Signal peptide peptidase- and ClpP-like proteins of Bacillus subtilis required for efficient translocation and processing of secretory proteins.
Bolhuis A, Matzen A, Hyyryläinen HL, Kontinen VP, Meima R, Chapuis J, Venema G, Bron S, Freudl R, van Dijl JM.
J Biol Chem. 1999 Aug 27;274(35):24585-92.
Functional analysis of paralogous thiol-disulfide oxidoreductases in Bacillus subtilis.
Bolhuis A, Venema G, Quax WJ, Bron S, van Dijl JM.
J Biol Chem. 1999 Aug 27;274(35):24531-8.
Evaluation of bottlenecks in the late stages of protein secretion in Bacillus subtilis.
Bolhuis A, Tjalsma H, Smith HE, de Jong A, Meima R, Venema G, Bron S, van Dijl JM.
Appl Environ Microbiol. 1999 Jul;65(7):2934-41.
Different mechanisms for thermal inactivation of Bacillus subtilis signal peptidase mutants.
Bolhuis A, Tjalsma H, Stephenson K, Harwood CR, Venema G, Bron S, van Dijl JM.
J Biol Chem. 1999 May 28;274(22):15865-8.
The plasmid-encoded signal peptidase SipP can functionally replace the major signal peptidases SipS and SipT of Bacillus subtilis.
Tjalsma H, van den Dolder J, Meijer WJ, Venema G, Bron S, van Dijl JM.
J Bacteriol. 1999 Apr;181(8):2448-54.
Membrane topology of the lactococcal bacteriocin ATP-binding cassette transporter protein LcnC. Involvement of LcnC in lactococcin a maturation.
Franke CM, Tiemersma J, Venema G, Kok J.
J Biol Chem. 1999 Mar 26;274(13):8484-90.
The role of lipoprotein processing by signal peptidase II in the Gram-positive eubacterium bacillus subtilis. Signal peptidase II is required for the efficient secretion of alpha-amylase, a non-lipoprotein.
Tjalsma H, Kontinen VP, Prágai Z, Wu H, Meima R, Venema G, Bron S, Sarvas M, van Dijl JM.
J Biol Chem. 1999 Jan 15;274(3):1698-707.
Early steps in the unfolding of thermolysin-like proteases.
Vriend G, Berendsen HJ, van den Burg B, Venema G, Eijsink VG.
J Biol Chem. 1998 Dec 25;273(52):35074-7.
Cloning, expression, and chromosomal stabilization of the Propionibacterium shermanii proline iminopeptidase gene (pip) for food-grade application in Lactococcus lactis.
Leenhouts K, Bolhuis A, Boot J, Deutz I, Toonen M, Venema G, Kok J, Ledeboer A.
Appl Environ Microbiol. 1998 Dec;64(12):4736-42.
Protein secretion and possible roles for multiple signal peptidases for precursor processing in bacilli.
Bron S, Bolhuis A, Tjalsma H, Holsappel S, Venema G, van Dijl JM.
J Biotechnol. 1998 Sep 17;64(1):3-13. Review.
Autolysis of Lactococcus lactis is influenced by proteolysis.
Buist G, Venema G, Kok J.
J Bacteriol. 1998 Nov;180(22):5947-53.
SecDF of Bacillus subtilis, a molecular Siamese twin required for the efficient secretion of proteins.
Bolhuis A, Broekhuizen CP, Sorokin A, van Roosmalen ML, Venema G, Bron S, Quax WJ, van Dijl JM.
J Biol Chem. 1998 Aug 14;273(33):21217-24.
Functional analysis of the secretory precursor processing machinery of Bacillus subtilis: identification of a eubacterial homolog of archaeal and eukaryotic signal peptidases.
Tjalsma H, Bolhuis A, van Roosmalen ML, Wiegert T, Schumann W, Broekhuizen CP, Quax WJ, Venema G, Bron S, van Dijl JM.
Genes Dev. 1998 Aug 1;12(15):2318-31.
Sequence specificity of illegitimate plasmid recombination in Bacillus subtilis: possible recognition sites for DNA topoisomerase I.
Meima R, Haan GJ, Venema G, Bron S, de Jong S.
Nucleic Acids Res. 1998 May 15;26(10):2366-73.
Construction of a food-grade multiple-copy integration system for Lactococcus lactis.
Leenhouts K, Bolhuis A, Venema G, Kok J.
Appl Microbiol Biotechnol. 1998 Apr;49(4):417-23.
Identification of a sodium chloride-regulated promoter in Lactococcus lactis by single-copy chromosomal fusion with a reporter gene.
Sanders JW, Venema G, Kok J, Leenhouts K.
Mol Gen Genet. 1998 Apr;257(6):681-5.
The competence transcription factor of Bacillus subtilis recognizes short A/T-rich sequences arranged in a unique, flexible pattern along the DNA helix.
Hamoen LW, Van Werkhoven AF, Bijlsma JJ, Dubnau D, Venema G.
Genes Dev. 1998 May 15;12(10):1539-50.
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