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Items: 11

1.

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.

Messick TE, Smith GR, Soldan SS, McDonnell ME, Deakyne JS, Malecka KA, Tolvinski L, van den Heuvel APJ, Gu BW, Cassel JA, Tran DH, Wassermann BR, Zhang Y, Velvadapu V, Zartler ER, Busson P, Reitz AB, Lieberman PM.

Sci Transl Med. 2019 Mar 6;11(482). pii: eaau5612. doi: 10.1126/scitranslmed.aau5612.

PMID:
30842315
2.

Stereochemistry of mephedrone neuropharmacology: enantiomer-specific behavioural and neurochemical effects in rats.

Gregg RA, Baumann MH, Partilla JS, Bonano JS, Vouga A, Tallarida CS, Velvadapu V, Smith GR, Peet MM, Reitz AB, Negus SS, Rawls SM.

Br J Pharmacol. 2015 Feb;172(3):883-94. doi: 10.1111/bph.12951. Epub 2014 Dec 15.

3.

Desmethyl macrolides: synthesis and evaluation of 4-desmethyl telithromycin.

Glassford I, Lee M, Wagh B, Velvadapu V, Paul T, Sandelin G, DeBrosse C, Klepacki D, Small MC, MacKerell AD Jr, Andrade RB.

ACS Med Chem Lett. 2014 Jul 16;5(9):1021-6. doi: 10.1021/ml5002097. eCollection 2014 Sep 11.

4.

Intramolecular Rearrangement of α-Amino Acid Amide Derivatives of 2-Aminobenzothiazoles.

Pelletier JC, Velvadapu V, McDonnell ME, Wrobel JE, Reitz AB.

Tetrahedron Lett. 2014 Jul 23;55(30):4193-4195.

5.

Facile Synthesis of Mutagen X (MX): 3-Chloro-4-(dichloromethyl)-5-hydroxy-5H-furan-2-one.

Velvadapu V, McDonnell ME, Jaffe EK, Reitz AB.

Tetrahedron Lett. 2012 Jun 20;53(25):3144-3146.

6.

Desmethyl Macrolides: Synthesis and Evaluation of 4,10-Didesmethyl Telithromycin.

Velvadapu V, Glassford I, Lee M, Paul T, Debrosse C, Klepacki D, Small MC, Mackerell AD Jr, Andrade RB.

ACS Med Chem Lett. 2012 Mar 8;3(3):211-215. Epub 2012 Jan 15.

7.

Characterization of a series of 4-aminoquinolines that stimulate caspase-7 mediated cleavage of TDP-43 and inhibit its function.

Cassel JA, McDonnell ME, Velvadapu V, Andrianov V, Reitz AB.

Biochimie. 2012 Sep;94(9):1974-81. doi: 10.1016/j.biochi.2012.05.020. Epub 2012 May 29.

8.

Total synthesis of (-)-4,8,10-tridesmethyl telithromycin.

Velvadapu V, Paul T, Wagh B, Glassford I, DeBrosse C, Andrade RB.

J Org Chem. 2011 Sep 16;76(18):7516-27. doi: 10.1021/jo201319b. Epub 2011 Aug 24.

9.

Desmethyl Macrolide Analogues to Address Antibiotic Resistance: Total Synthesis and Biological Evaluation of 4,8,10-Tridesmethyl Telithromycin.

Velvadapu V, Paul T, Wagh B, Klepacki D, Guvench O, Mackerell A Jr, Andrade RB.

ACS Med Chem Lett. 2011 Jan 13;2(1):68-72.

10.

Synthesis of polysubstituted pyrroles from sulfinimines (N-sulfinyl imines).

Davis FA, Bowen KA, Xu H, Velvadapu V.

Tetrahedron. 2008 May 5;64(19):4174-4182.

11.

Concise syntheses of D-desosamine, 2-thiopyrimidinyl desosamine donors, and methyl desosaminide analogues from D-glucose.

Velvadapu V, Andrade RB.

Carbohydr Res. 2008 Jan 14;343(1):145-50. Epub 2007 Oct 14.

PMID:
17977522

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