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It's a Storm, It's a Gale: Epilepsy Initiation From the Corticostriatal Circuit.

Velíšek L.

Epilepsy Curr. 2019 Sep;19(5):333-335. doi: 10.1177/1535759719870514. Epub 2019 Aug 27.


Epilepsy Did it Again: Memory and Model-Based Planning Studied in Patients After Epilepsy Surgery.

Velíšek L.

Epilepsy Curr. 2019 Jul-Aug;19(4):264-265. doi: 10.1177/1535759719857069. Epub 2019 Jun 21.


Tetramethylenedisulfotetramine neurotoxicity: What have we learned in the past 70 years?

Lauková M, Velíšková J, Velíšek L, Shakarjian MP.

Neurobiol Dis. 2019 Jun 6:104491. doi: 10.1016/j.nbd.2019.104491. [Epub ahead of print] Review.


Mouse model of human poisonings with tetramethylenedisulfotetramine: Characterization of the effect of exposure route on syndrome outcomes.

Lauková M, Pervez S, Rosman R, Velíšková J, Velíšek L, Shakarjian MP.

Toxicol Lett. 2019 Jun 15;308:50-55. doi: 10.1016/j.toxlet.2019.03.014. Epub 2019 Mar 30.


AQB-565 shows promise in preclinical testing in the model of epileptic spasms during infancy: Head-to-head comparison with ACTH.

Chern CR, Chern CJ, Velíšková J, Velíšek L.

Epilepsy Res. 2019 May;152:31-34. doi: 10.1016/j.eplepsyres.2019.03.004. Epub 2019 Mar 11.


Astrocyte and Neuronal Pannexin1 Contribute Distinctly to Seizures.

Scemes E, Velíšek L, Velíšková J.

ASN Neuro. 2019 Jan-Dec;11:1759091419833502. doi: 10.1177/1759091419833502.


"Are We There Yet?" Quest for Treatment of Refractory Epilepsy.

Velíšek L.

Epilepsy Curr. 2019 Jan;19(1):57-58. doi: 10.1177/1535759718822843. Epub 2019 Feb 12.


"Can You Hear Me Now?" AMPA Receptor-Mediated Tonotopy Disruption by Early Life Seizures.

Velíšek L.

Epilepsy Curr. 2018 Nov-Dec;18(6):391-393. doi: 10.5698/1535-7597.18.6.391. No abstract available.


"Shake it off" Versus "In Your Wildest Dreams": Thalamus as a Consciousness Gate for Temporal Lobe Seizures.

Velíšek L.

Epilepsy Curr. 2018 Jul-Aug;18(4):248-250. doi: 10.5698/1535-7597.18.4.248. No abstract available.


Regeneration of neurotransmission transcriptome in a model of epileptic encephalopathy after antiinflammatory treatment.

Iacobas DA, Velíšek L.

Neural Regen Res. 2018 Oct;13(10):1715-1718. doi: 10.4103/1673-5374.238607. Review.


Estrogen Protects Neurotransmission Transcriptome During Status Epilepticus.

Iacobas DA, Iacobas S, Nebieridze N, Velíšek L, Velíšková J.

Front Neurosci. 2018 Jun 20;12:332. doi: 10.3389/fnins.2018.00332. eCollection 2018.


In Vivo Multimodal Magnetic Resonance Imaging Changes After N-Methyl-d-Aspartate-Triggered Spasms in Infant Rats.

Lee M, Yum MS, Woo DC, Shim WH, Ko TS, Velíšek L.

Front Neurol. 2018 Apr 16;9:248. doi: 10.3389/fneur.2018.00248. eCollection 2018.


ACTH and PMX53 recover synaptic transcriptome alterations in a rat model of infantile spasms.

Iacobaş DA, Chachua T, Iacobaş S, Benson MJ, Borges K, Velíšková J, Velíšek L.

Sci Rep. 2018 Apr 10;8(1):5722. doi: 10.1038/s41598-018-24013-x.


Developmental and sex differences in tetramethylenedisulfotetramine (TMDT)-induced syndrome in rats.

Lauková M, Velíšková J, Velíšek L, Shakarjian MP.

Dev Neurobiol. 2018 Apr;78(4):403-416. doi: 10.1002/dneu.22582. Epub 2018 Feb 14.


Theta is the New Alpha.

Velíšek L.

Epilepsy Curr. 2017 Sep-Oct;17(5):314-316. doi: 10.5698/1535-7597.17.5.314. No abstract available.


Everybody's Got the Fever…Be it Fahrenheit or Centigrade.

Velíšek L.

Epilepsy Curr. 2017 Sep-Oct;17(5):303-305. doi: 10.5698/1535-7597.17.5.303. No abstract available.


Knockin' Out the Spasms.

Velíšek L.

Epilepsy Curr. 2017 May-Jun;17(3):177-179. doi: 10.5698/1535-7511.17.3.177. No abstract available.


Puritan's View of the "Ménage à Trois".

Velisek L.

Epilepsy Curr. 2017 Mar-Apr;17(2):115-117. doi: 10.5698/1535-7511.17.2.115. No abstract available.


Taming the rAMPAnt Fire with Fat.

Velíšek L.

Epilepsy Curr. 2017 Jan-Feb;17(1):54-56. doi: 10.5698/1535-7511-17.1.54. No abstract available.


Under the (Light) Sheet After the iDISCO.

Velíšek L.

Epilepsy Curr. 2016 Nov-Dec;16(6):405-407. No abstract available.


Tetramethylenedisulfotetramine: pest control gone awry.

Shakarjian MP, Laukova M, Velíšková J, Stanton PK, Heck DE, Velíšek L.

Ann N Y Acad Sci. 2016 Aug;1378(1):68-79. doi: 10.1111/nyas.13120. Epub 2016 Jul 6. Review.


Follow Thy Bear: The NMDA Receptor Antibodies Are Epileptogenic.

Velíšek L.

Epilepsy Curr. 2016 May-Jun;16(3):174-6. doi: 10.5698/1535-7511-16.3.174. No abstract available.


Estradiol does not affect spasms in the betamethasone-NMDA rat model of infantile spasms.

Chachua T, Di Grazia P, Chern CR, Johnkutty M, Hellman B, Lau HA, Shakil F, Daniel M, Goletiani C, Velíšková J, Velíšek L.

Epilepsia. 2016 Aug;57(8):1326-36. doi: 10.1111/epi.13434. Epub 2016 Jun 22.


Oestradiol Regulates Neuropeptide Y Release and Gene Coupling with the GABAergic and Glutamatergic Synapses in the Adult Female Rat Dentate Gyrus.

Velíšková J, Iacobas D, Iacobas S, Sidyelyeva G, Chachua T, Velíšek L.

J Neuroendocrinol. 2015 Dec;27(12):911-20. doi: 10.1111/jne.12332.


β-Hydroxybutyrate attenuates NMDA-induced spasms in rats with evidence of neuronal stabilization on MR spectroscopy.

Yum MS, Lee M, Woo DC, Kim DW, Ko TS, Velíšek L.

Epilepsy Res. 2015 Nov;117:125-32. doi: 10.1016/j.eplepsyres.2015.08.005. Epub 2015 Aug 8.


To Arouse Or Not To Arouse: The Cholinergic Question.

Velíšek L.

Epilepsy Curr. 2015 Jul-Aug;15(4):219-20. doi: 10.5698/1535-7511-15.4.219. No abstract available.


Combined diazepam and MK-801 therapy provides synergistic protection from tetramethylenedisulfotetramine-induced tonic-clonic seizures and lethality in mice.

Shakarjian MP, Ali MS, Velíšková J, Stanton PK, Heck DE, Velíšek L.

Neurotoxicology. 2015 May;48:100-8. doi: 10.1016/j.neuro.2015.03.007. Epub 2015 Mar 14.


Region-specific MRI t2 relaxation times predict epileptogenesis.

Velíšek L.

Epilepsy Curr. 2015 Jan-Feb;15(1):41-2. doi: 10.5698/1535-7597-15.1.41. No abstract available.


A potential effect of ganaxolone in an animal model of infantile spasms.

Yum MS, Lee M, Ko TS, Velíšek L.

Epilepsy Res. 2014 Nov;108(9):1492-500. doi: 10.1016/j.eplepsyres.2014.08.015. Epub 2014 Sep 2.


Sex-specific behavioral traits in the Brd2 mouse model of juvenile myoclonic epilepsy.

Chachua T, Goletiani C, Maglakelidze G, Sidyelyeva G, Daniel M, Morris E, Miller J, Shang E, Wolgemuth DJ, Greenberg DA, Velíšková J, Velíšek L.

Genes Brain Behav. 2014 Sep;13(7):702-12. doi: 10.1111/gbb.12160. Epub 2014 Aug 28.


Prenatal corticosteroids modify glutamatergic and GABAergic synapse genomic fabric: insights from a novel animal model of infantile spasms.

Iacobas DA, Iacobas S, Chachua T, Goletiani C, Sidyelyeva G, Velíšková J, Velíšek L.

J Neuroendocrinol. 2013 Nov;25(11):964-79. doi: 10.1111/jne.12061. Review.


Anti-seizure medications and estradiol for neuroprotection in epilepsy: the 2013 update.

Velisek L, Nebieridze N, Chachua T, Veliskova J.

Recent Pat CNS Drug Discov. 2013 Apr;8(1):24-41. Review.


Differential antagonism of tetramethylenedisulfotetramine-induced seizures by agents acting at NMDA and GABA(A) receptors.

Shakarjian MP, Velíšková J, Stanton PK, Velíšek L.

Toxicol Appl Pharmacol. 2012 Nov 15;265(1):113-21. doi: 10.1016/j.taap.2012.08.037. Epub 2012 Sep 27.


Rapamycin has age-, treatment paradigm-, and model-specific anticonvulsant effects and modulates neuropeptide Y expression in rats.

Chachua T, Poon KL, Yum MS, Nesheiwat L, DeSantis K, Velíšková J, Velíšek L.

Epilepsia. 2012 Nov;53(11):2015-25. doi: 10.1111/j.1528-1167.2012.03674.x. Epub 2012 Sep 27.


Finding a better drug for epilepsy: preclinical screening strategies and experimental trial design.

Simonato M, Löscher W, Cole AJ, Dudek FE, Engel J Jr, Kaminski RM, Loeb JA, Scharfman H, Staley KJ, Velíšek L, Klitgaard H.

Epilepsia. 2012 Nov;53(11):1860-7. doi: 10.1111/j.1528-1167.2012.03541.x. Epub 2012 Jun 18. Review.


Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

Goldstein LE, Fisher AM, Tagge CA, Zhang XL, Velisek L, Sullivan JA, Upreti C, Kracht JM, Ericsson M, Wojnarowicz MW, Goletiani CJ, Maglakelidze GM, Casey N, Moncaster JA, Minaeva O, Moir RD, Nowinski CJ, Stern RA, Cantu RC, Geiling J, Blusztajn JK, Wolozin BL, Ikezu T, Stein TD, Budson AE, Kowall NW, Chargin D, Sharon A, Saman S, Hall GF, Moss WC, Cleveland RO, Tanzi RE, Stanton PK, McKee AC.

Sci Transl Med. 2012 May 16;4(134):134ra60. doi: 10.1126/scitranslmed.3003716.


β-Estradiol unmasks metabotropic receptor-mediated metaplasticity of NMDA receptor transmission in the female rat dentate gyrus.

Nebieridze N, Zhang XL, Chachua T, Velíšek L, Stanton PK, Velíšková J.

Psychoneuroendocrinology. 2012 Nov;37(11):1845-54. doi: 10.1016/j.psyneuen.2012.03.023. Epub 2012 Apr 27.


Altered neurotransmitter release, vesicle recycling and presynaptic structure in the pilocarpine model of temporal lobe epilepsy.

Upreti C, Otero R, Partida C, Skinner F, Thakker R, Pacheco LF, Zhou ZY, Maglakelidze G, Velíšková J, Velíšek L, Romanovicz D, Jones T, Stanton PK, Garrido-Sanabria ER.

Brain. 2012 Mar;135(Pt 3):869-85. doi: 10.1093/brain/awr341. Epub 2012 Feb 16.


Prenatal stress promotes development of spasms in infant rats.

Yum MS, Chachua T, Velíšková J, Velíšek L.

Epilepsia. 2012 Mar;53(3):e46-9. doi: 10.1111/j.1528-1167.2011.03357.x. Epub 2011 Dec 22.


GABAergic neuron deficit as an idiopathic generalized epilepsy mechanism: the role of BRD2 haploinsufficiency in juvenile myoclonic epilepsy.

Velíšek L, Shang E, Velíšková J, Chachua T, Macchiarulo S, Maglakelidze G, Wolgemuth DJ, Greenberg DA.

PLoS One. 2011;6(8):e23656. doi: 10.1371/journal.pone.0023656. Epub 2011 Aug 24.


Validation of the rat model of cryptogenic infantile spasms.

Chachua T, Yum MS, Velíšková J, Velíšek L.

Epilepsia. 2011 Sep;52(9):1666-77. doi: 10.1111/j.1528-1167.2011.03220.x. Epub 2011 Aug 19.


Prenatal corticosteroid exposure alters early developmental seizures and behavior.

Velíšek L.

Epilepsy Res. 2011 Jun;95(1-2):9-19. doi: 10.1016/j.eplepsyres.2011.01.019. Epub 2011 Mar 22.


Model of cryptogenic infantile spasms after prenatal corticosteroid priming.

Velísek L, Chachua T, Yum MS, Poon KL, Velísková J.

Epilepsia. 2010 Jul;51 Suppl 3:145-9. doi: 10.1111/j.1528-1167.2010.02630.x.


Females, their estrogens, and seizures.

Velísková J, De Jesus G, Kaur R, Velísek L.

Epilepsia. 2010 Jul;51 Suppl 3:141-4. doi: 10.1111/j.1528-1167.2010.02629.x.


Metabolic environment in substantia nigra reticulata is critical for the expression and control of hypoglycemia-induced seizures.

Velísek L, Velísková J, Chudomel O, Poon KL, Robeson K, Marshall B, Sharma A, Moshé SL.

J Neurosci. 2008 Sep 17;28(38):9349-62. doi: 10.1523/JNEUROSCI.3195-08.2008.


Age, sex, and hormonal status can be additional variables in prenatal dexamethasone exposure.

Velísek L.

Neurosci Res. 2008 Aug;61(4):333-4. doi: 10.1016/j.neures.2008.05.001. Epub 2008 May 8.


New avenue of research: antiepileptic drug and estradiol neuroprotection in epilepsy.

Velísek L, Velísková J.

Recent Pat CNS Drug Discov. 2008 Jun;3(2):128-37. Review.


The involvement of the substantia nigra pars reticulata in hypoglycemic seizures.

Velísková J, Chudomel O, Poon KL, Marshall B, Velísek L.

Epilepsia. 2007;48 Suppl 5:106-8. Erratum in: Epilepsia. 2007 Dec;48(12):2380.


Age-dependent consequences of status epilepticus: animal models.

Scantlebury MH, Heida JG, Hasson HJ, Velísková J, Velísek L, Galanopoulou AS, Moshé SL.

Epilepsia. 2007;48 Suppl 2:75-82.

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