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Items: 1 to 50 of 53

1.

Absence of Functional Nav1.8 Channels in Non-diseased Atrial and Ventricular Cardiomyocytes.

Casini S, Marchal GA, Kawasaki M, Nariswari FA, Portero V, van den Berg NWE, Guan K, Driessen AHG, Veldkamp MW, Mengarelli I, de Groot JR, Verkerk AO, Remme CA.

Cardiovasc Drugs Ther. 2020 Jan 8. doi: 10.1007/s10557-019-06925-6. [Epub ahead of print]

PMID:
31916131
2.

Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation.

Scherschel K, Hedenus K, Jungen C, Lemoine MD, Rübsamen N, Veldkamp MW, Klatt N, Lindner D, Westermann D, Casini S, Kuklik P, Eickholt C, Klöcker N, Shivkumar K, Christ T, Zeller T, Willems S, Meyer C.

Sci Transl Med. 2019 May 22;11(493). pii: eaav7770. doi: 10.1126/scitranslmed.aav7770.

PMID:
31118294
3.

Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel.

Veldkamp MW, Geuzebroek GSC, Baartscheer A, Verkerk AO, Schumacher CA, Suarez GG, Berger WR, Casini S, van Amersfoorth SCM, Scholman KT, Driessen AHG, Belterman CNW, van Ginneken ACG, de Groot JR, de Bakker JMT, Remme CA, Boukens BJ, Coronel R.

Nat Commun. 2018 Oct 19;9(1):4357. doi: 10.1038/s41467-018-06530-5.

4.

Is IGF-1 a useful inhibitor of Na+ /H+ -exchanger activity?

Baartscheer A, Veldkamp MW.

Acta Physiol (Oxf). 2018 Oct;224(2):e13164. doi: 10.1111/apha.13164. Epub 2018 Aug 13. No abstract available.

PMID:
30039514
5.

Can we spice up our Christmas dinner? : Busting the myth of the 'Chinese restaurant syndrome'.

van den Berg NWE, Neefs J, Berger WR, Baalman SWE, Meulendijks E, Kawasaki M, Kemper EM, Piersma FR, Veldkamp MW, Wesselink R, Krul SPJ, de Groot JR.

Neth Heart J. 2017 Dec;25(12):664-668. doi: 10.1007/s12471-017-1053-5.

6.

Anti-arrhythmic potential of the late sodium current inhibitor GS-458967 in murine Scn5a-1798insD+/- and human SCN5A-1795insD+/- iPSC-derived cardiomyocytes.

Portero V, Casini S, Hoekstra M, Verkerk AO, Mengarelli I, Belardinelli L, Rajamani S, Wilde AAM, Bezzina CR, Veldkamp MW, Remme CA.

Cardiovasc Res. 2017 Jun 1;113(7):829-838. doi: 10.1093/cvr/cvx077.

PMID:
28430892
7.

Disruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias.

Jungen C, Scherschel K, Eickholt C, Kuklik P, Klatt N, Bork N, Salzbrunn T, Alken F, Angendohr S, Klene C, Mester J, Klöcker N, Veldkamp MW, Schumacher U, Willems S, Nikolaev VO, Meyer C.

Nat Commun. 2017 Jan 27;8:14155. doi: 10.1038/ncomms14155.

8.

Letter by Baartscheer et al Regarding Editorial, "Matter of Fat: Are Lipids Antiarrhythmic?".

Baartscheer A, Veldkamp MW, Coronel R.

Circ Arrhythm Electrophysiol. 2016 Mar;9(3):e003933. doi: 10.1161/CIRCEP.116.003933. No abstract available.

PMID:
26888447
9.

Treatment of Atrial and Ventricular Arrhythmias Through Autonomic Modulation.

Krul SPJ, Berger WR, Veldkamp MW, Driessen AHG, Wilde AAM, Deneke T, de Bakker JMT, Coronel R, de Groot JR.

JACC Clin Electrophysiol. 2015 Dec;1(6):496-508. doi: 10.1016/j.jacep.2015.09.013. Epub 2015 Oct 24. Review.

10.

Dyscholesterolemia Protects Against Ischemia-Induced Ventricular Arrhythmias.

Baartscheer A, Schumacher CA, Wekker V, Verkerk AO, Veldkamp MW, van Oort RJ, Elzenaar I, Ottenhoff R, van Roomen C, Aerts H, Coronel R.

Circ Arrhythm Electrophysiol. 2015 Dec;8(6):1481-90. doi: 10.1161/CIRCEP.115.002751. Epub 2015 Oct 1.

PMID:
26429563
11.

A heterozygous deletion mutation in the cardiac sodium channel gene SCN5A with loss- and gain-of-function characteristics manifests as isolated conduction disease, without signs of Brugada or long QT syndrome.

Zumhagen S, Veldkamp MW, Stallmeyer B, Baartscheer A, Eckardt L, Paul M, Remme CA, Bhuiyan ZA, Bezzina CR, Schulze-Bahr E.

PLoS One. 2013 Jun 28;8(6):e67963. doi: 10.1371/journal.pone.0067963. Print 2013.

12.

Organ explant culture of neonatal rat ventricles: a new model to study gene and cell therapy.

den Haan AD, Veldkamp MW, Bakker D, Boink GJ, Janssen RB, de Bakker JM, Tan HL.

PLoS One. 2013;8(3):e59290. doi: 10.1371/journal.pone.0059290. Epub 2013 Mar 13.

13.

Effects of acetylcholine and noradrenalin on action potentials of isolated rabbit sinoatrial and atrial myocytes.

Verkerk AO, Geuzebroek GS, Veldkamp MW, Wilders R.

Front Physiol. 2012 May 31;3:174. doi: 10.3389/fphys.2012.00174. eCollection 2012.

14.

Functional Nav1.8 channels in intracardiac neurons: the link between SCN10A and cardiac electrophysiology.

Verkerk AO, Remme CA, Schumacher CA, Scicluna BP, Wolswinkel R, de Jonge B, Bezzina CR, Veldkamp MW.

Circ Res. 2012 Jul 20;111(3):333-43. doi: 10.1161/CIRCRESAHA.112.274035. Epub 2012 Jun 20.

PMID:
22723301
15.

Tubulin polymerization modifies cardiac sodium channel expression and gating.

Casini S, Tan HL, Demirayak I, Remme CA, Amin AS, Scicluna BP, Chatyan H, Ruijter JM, Bezzina CR, van Ginneken AC, Veldkamp MW.

Cardiovasc Res. 2010 Mar 1;85(4):691-700. doi: 10.1093/cvr/cvp352. Epub 2009 Oct 26.

PMID:
19861310
16.

Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy.

Remme CA, Scicluna BP, Verkerk AO, Amin AS, van Brunschot S, Beekman L, Deneer VH, Chevalier C, Oyama F, Miyazaki H, Nukina N, Wilders R, Escande D, Houlgatte R, Wilde AA, Tan HL, Veldkamp MW, de Bakker JM, Bezzina CR.

Circ Res. 2009 Jun 5;104(11):1283-92. doi: 10.1161/CIRCRESAHA.109.194423. Epub 2009 Apr 30.

PMID:
19407241
17.

The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium.

Remme CA, Verkerk AO, Hoogaars WM, Aanhaanen WT, Scicluna BP, Annink C, van den Hoff MJ, Wilde AA, van Veen TA, Veldkamp MW, de Bakker JM, Christoffels VM, Bezzina CR.

Basic Res Cardiol. 2009 Sep;104(5):511-22. doi: 10.1007/s00395-009-0012-8. Epub 2009 Mar 3.

18.

Intracellular calcium modulation of voltage-gated sodium channels in ventricular myocytes.

Casini S, Verkerk AO, van Borren MM, van Ginneken AC, Veldkamp MW, de Bakker JM, Tan HL.

Cardiovasc Res. 2009 Jan 1;81(1):72-81. doi: 10.1093/cvr/cvn274. Epub 2008 Oct 1.

PMID:
18829699
19.

Diversity in cardiac sodium channel disease phenotype in transgenic mice carrying a single SCN5A mutation.

Remme CA, Verkerk AO, Wilde AA, Veldkamp MW, de Bakker JM, Bezzina CR.

Neth Heart J. 2007;15(6):235-8. No abstract available.

20.

Characterization of a novel SCN5A mutation associated with Brugada syndrome reveals involvement of DIIIS4-S5 linker in slow inactivation.

Casini S, Tan HL, Bhuiyan ZA, Bezzina CR, Barnett P, Cerbai E, Mugelli A, Wilde AA, Veldkamp MW.

Cardiovasc Res. 2007 Dec 1;76(3):418-29. Epub 2007 Aug 22.

PMID:
17854786
21.

Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD.

Remme CA, Verkerk AO, Nuyens D, van Ginneken AC, van Brunschot S, Belterman CN, Wilders R, van Roon MA, Tan HL, Wilde AA, Carmeliet P, de Bakker JM, Veldkamp MW, Bezzina CR.

Circulation. 2006 Dec 12;114(24):2584-94. Epub 2006 Dec 4.

PMID:
17145985
22.

Incorporated sarcolemmal fish oil fatty acids shorten pig ventricular action potentials.

Verkerk AO, van Ginneken AC, Berecki G, den Ruijter HM, Schumacher CA, Veldkamp MW, Baartscheer A, Casini S, Opthof T, Hovenier R, Fiolet JW, Zock PL, Coronel R.

Cardiovasc Res. 2006 Jun 1;70(3):509-20. Epub 2006 Feb 28.

PMID:
16564514
23.

Gender disparities in cardiac cellular electrophysiology and arrhythmia susceptibility in human failing ventricular myocytes.

Verkerk AO, Wilders R, Veldkamp MW, de Geringel W, Kirkels JH, Tan HL.

Int Heart J. 2005 Nov;46(6):1105-18.

24.

Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study.

Coronel R, Casini S, Koopmann TT, Wilms-Schopman FJ, Verkerk AO, de Groot JR, Bhuiyan Z, Bezzina CR, Veldkamp MW, Linnenbank AC, van der Wal AC, Tan HL, Brugada P, Wilde AA, de Bakker JM.

Circulation. 2005 Nov 1;112(18):2769-77.

PMID:
16267250
25.

Substitution of a conserved alanine in the domain IIIS4-S5 linker of the cardiac sodium channel causes long QT syndrome.

Smits JP, Veldkamp MW, Bezzina CR, Bhuiyan ZA, Wedekind H, Schulze-Bahr E, Wilde AA.

Cardiovasc Res. 2005 Aug 15;67(3):459-66.

PMID:
16039271
26.

A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families.

Smits JP, Koopmann TT, Wilders R, Veldkamp MW, Opthof T, Bhuiyan ZA, Mannens MM, Balser JR, Tan HL, Bezzina CR, Wilde AA.

J Mol Cell Cardiol. 2005 Jun;38(6):969-81. Epub 2005 Apr 1.

PMID:
15910881
27.

Mechanisms of inherited cardiac conduction disease.

Smits JP, Veldkamp MW, Wilde AA.

Europace. 2005 Mar;7(2):122-37. Review.

PMID:
15763526
28.

HERG channel (dys)function revealed by dynamic action potential clamp technique.

Berecki G, Zegers JG, Verkerk AO, Bhuiyan ZA, de Jonge B, Veldkamp MW, Wilders R, van Ginneken AC.

Biophys J. 2005 Jan;88(1):566-78. Epub 2004 Oct 8.

29.

Contribution of sodium channel mutations to bradycardia and sinus node dysfunction in LQT3 families.

Veldkamp MW, Wilders R, Baartscheer A, Zegers JG, Bezzina CR, Wilde AA.

Circ Res. 2003 May 16;92(9):976-83. Epub 2003 Apr 3.

PMID:
12676817
30.

A large family characterised by nocturnal sudden death.

van den Berg MP, Viersma JW, Beaufort-Krol GC, Bink-Boelkens MT, Bezzina CR, Veldkamp MW, Brouwer J, Haaksma J, van Tintelen JP, van Langen IM, Wouda AA, Wilde AA.

Neth Heart J. 2002 Aug;10(7-8):304-312.

31.

Ionic mechanism of delayed afterdepolarizations in ventricular cells isolated from human end-stage failing hearts.

Verkerk AO, Veldkamp MW, Baartscheer A, Schumacher CA, Klöpping C, van Ginneken AC, Ravesloot JH.

Circulation. 2001 Nov 27;104(22):2728-33.

PMID:
11723027
32.

De novo mutation in the SCN5A gene associated with early onset of sudden infant death.

Wedekind H, Smits JP, Schulze-Bahr E, Arnold R, Veldkamp MW, Bajanowski T, Borggrefe M, Brinkmann B, Warnecke I, Funke H, Bhuiyan ZA, Wilde AA, Breithardt G, Haverkamp W.

Circulation. 2001 Sep 4;104(10):1158-64.

PMID:
11535573
33.

Cl- current blockade reduces triggered activity based on delayed afterdepolarisations.

Verkerk AO, Veldkamp MW, van Ginneken AC.

Neth Heart J. 2001 Aug;9(4-5):172-176. Review.

34.

Role of Ca(2+)-activated Cl(-) current in ventricular action potentials of sheep during adrenoceptor stimulation.

Verkerk AO, Schumacher CA, van Ginneken AC, Veldkamp MW, Ravesloot JH.

Exp Physiol. 2001 Mar;86(2):151-9.

PMID:
11429629
35.

Norepinephrine induces action potential prolongation and early afterdepolarizations in ventricular myocytes isolated from human end-stage failing hearts.

Veldkamp MW, Verkerk AO, van Ginneken AC, Baartscheer A, Schumacher C, de Jonge N, de Bakker JM, Opthof T.

Eur Heart J. 2001 Jun;22(11):955-63.

PMID:
11428819
36.

Effects of cell-to-cell uncoupling and catecholamines on Purkinje and ventricular action potentials: implications for phase-1b arrhythmias.

Verkerk AO, Veldkamp MW, Coronel R, Wilders R, van Ginneken AC.

Cardiovasc Res. 2001 Jul;51(1):30-40.

PMID:
11399245
37.

Decrease of delayed rectifier currents in the subacute phase of infarction.

Veldkamp MW.

Cardiovasc Res. 2000 Oct;48(1):11-2. No abstract available.

PMID:
11033103
38.

Injury current modulates afterdepolarizations in single human ventricular cells.

Verkerk AO, Veldkamp MW, de Jonge N, Wilders R, van Ginneken AC.

Cardiovasc Res. 2000 Jul;47(1):124-32.

PMID:
10869538
39.

Calcium-activated Cl(-) current contributes to delayed afterdepolarizations in single Purkinje and ventricular myocytes.

Verkerk AO, Veldkamp MW, Bouman LN, van Ginneken AC.

Circulation. 2000 Jun 6;101(22):2639-44.

PMID:
10840017
40.

Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel.

Veldkamp MW, Viswanathan PC, Bezzina C, Baartscheer A, Wilde AA, Balser JR.

Circ Res. 2000 May 12;86(9):E91-7.

PMID:
10807877
41.

What we can learn from individual resuscitated patients.

Wilde AA, Veldkamp MW.

Cardiovasc Res. 2000 Apr;46(1):14-6. No abstract available.

PMID:
10727647
42.

A single Na(+) channel mutation causing both long-QT and Brugada syndromes.

Bezzina C, Veldkamp MW, van Den Berg MP, Postma AV, Rook MB, Viersma JW, van Langen IM, Tan-Sindhunata G, Bink-Boelkens MT, van Der Hout AH, Mannens MM, Wilde AA.

Circ Res. 1999 Dec 3-17;85(12):1206-13.

PMID:
10590249
43.

Implications of inhomogeneous distribution of IKS and IKr channels in ventricle with respect to effects of class III agents and beta-agonists.

van Ginneken AC, Veldkamp MW.

Cardiovasc Res. 1999 Jul;43(1):20-2. Review. No abstract available.

PMID:
10536685
44.

Decreased inward rectifier current in adult rabbit ventricular myocytes maintained in primary culture: a single-channel study.

Veldkamp MW, de Jonge B, van Ginneken AC.

Cardiovasc Res. 1999 May;42(2):424-33.

PMID:
10533578
45.

Two types of action potential configuration in single cardiac Purkinje cells of sheep.

Verkerk AO, Veldkamp MW, Abbate F, Antoons G, Bouman LN, Ravesloot JH, van Ginneken AC.

Am J Physiol. 1999 Oct;277(4):H1299-310. doi: 10.1152/ajpheart.1999.277.4.H1299.

PMID:
10516164
46.

Is the slowly activating component of the delayed rectifier current, IKs' absent from undiseased human ventricular myocardium?

Veldkamp MW.

Cardiovasc Res. 1998 Dec;40(3):433-5. Review. No abstract available.

PMID:
10070481
47.

Ion channels, the QT interval, and arrhythmias.

Wilde AA, Veldkamp MW.

Pacing Clin Electrophysiol. 1997 Aug;20(8 Pt 2):2048-51. Review.

PMID:
9272506
48.
49.

Delayed rectifier channels in human ventricular myocytes.

Veldkamp MW, van Ginneken AC, Opthof T, Bouman LN.

Circulation. 1995 Dec 15;92(12):3497-504.

PMID:
8521572
50.

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