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Upregulation of SMYD3 and SMYD3 VNTR 3/3 polymorphism increase the risk of hepatocellular carcinoma.

Binh MT, Hoan NX, Giang DP, Tong HV, Bock CT, Wedemeyer H, Toan NL, Bang MH, Kremsner PG, Meyer CG, Song LH, Velavan TP.

Sci Rep. 2020 Feb 18;10(1):2797. doi: 10.1038/s41598-020-59667-z.


The COVID-19 epidemic.

Velavan TP, Meyer CG.

Trop Med Int Health. 2020 Feb 12. doi: 10.1111/tmi.13383. [Epub ahead of print] No abstract available.


2019-nCoV in context: lessons learned?

Kock RA, Karesh WB, Veas F, Velavan TP, Simons D, Mboera LEG, Dar O, Arruda LB, Zumla A.

Lancet Planet Health. 2020 Feb 6. pii: S2542-5196(20)30035-8. doi: 10.1016/S2542-5196(20)30035-8. [Epub ahead of print] No abstract available.


Vitamin D receptor ApaI polymorphism associated with progression of liver disease in Vietnamese patients chronically infected with hepatitis B virus.

Hoan NX, Khuyen N, Giang DP, Binh MT, Toan NL, Anh DT, Trung NT, Bang MH, Meyer CG, Velavan TP, Song LH.

BMC Med Genet. 2019 Dec 21;20(1):201. doi: 10.1186/s12881-019-0903-y.


Monitoring of efficacy, tolerability and safety of artemether-lumefantrine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Lambaréné, Gabon: an open-label clinical trial.

Adegbite BR, Edoa JR, Honkpehedji YJ, Zinsou FJ, Dejon-Agobe JC, Mbong-Ngwese M, Lotola-Mougueni F, Koehne E, Lalremruata A, Kreidenweiss A, Nguyen TT, Kun J, Agnandji ST, Lell B, Safiou AR, Obone Atome FA, Mombo-Ngoma G, Ramharter M, Velavan TP, Mordmüller B, Kremsner PG, Adegnika AA.

Malar J. 2019 Dec 16;18(1):424. doi: 10.1186/s12936-019-3015-4.


Neopterin levels and Kyn/Trp ratios were significantly increased in dengue virus patients and subsequently decreased after recovery.

Geisler S, Lytton SD, Toan NL, Nghia TH, Nam NM, Hung HV, Son NT, Anh DT, Tuyen HT, Tien TV, Quyet D, Van Tong H, Hoan NX, Song LH, Pallerla SR, Gostner JM, Fuchs D, Velavan TP.

Int J Infect Dis. 2020 Feb;91:162-168. doi: 10.1016/j.ijid.2019.12.005. Epub 2019 Dec 9.


High Hepatitis E virus (HEV) Positivity Among Domestic Pigs and Risk of HEV Infection of Individuals Occupationally Exposed to Pigs and Pork Meat in Hanoi, Vietnam.

Hoan NX, Huy PX, Sy BT, Meyer CG, Son TV, Binh MT, Giang DP, Tu Anh D, Bock CT, Wang B, Tong HV, Kremsner PG, Song LH, Toan NL, Velavan TP.

Open Forum Infect Dis. 2019 Jun 26;6(9):ofz306. doi: 10.1093/ofid/ofz306. eCollection 2019 Sep.


Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of chloroquine.

Ikegbunam MN, Nkonganyi CN, Thomas BN, Esimone CO, Velavan TP, Ojurongbe O.

Malar J. 2019 Oct 7;18(1):343. doi: 10.1186/s12936-019-2977-6.


DNA recovery from archived RDTs for genetic characterization of Plasmodium falciparum in a routine setting in Lambaréné, Gabon.

Nguyen TT, Nzigou Mombo B, Lalremruata A, Koehne E, Zoleko Manego R, Dimessa Mbadinga LB, Adegnika AA, Agnandji ST, Lell B, Kremsner PG, Velavan TP, Ramharter M, Mordmüller B, Mombo-Ngoma G.

Malar J. 2019 Oct 2;18(1):336. doi: 10.1186/s12936-019-2972-y.


Rapid, low cost and sensitive detection of Calreticulin mutations by a PCR based amplicon length differentiation assay for diagnosis of myeloproliferative neoplasms.

Trung NT, Quyen DT, Hoan NX, Giang DP, Trang TTH, Velavan TP, Bang MH, Song LH.

BMC Med Genet. 2019 Jun 27;20(1):115. doi: 10.1186/s12881-019-0819-6.


An alternative dogma on reduced artemisinin susceptibility: A new shadow from east to west.

Velavan TP, Nderu D, Agbenyega T, Ntoumi F, Kremsner PG.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12611-12612. doi: 10.1073/pnas.1907142116. No abstract available.


Molecular surveillance of pfhrp2 and pfhrp3 genes deletion in Plasmodium falciparum isolates and the implications for rapid diagnostic tests in Nigeria.

Funwei R, Nderu D, Nguetse CN, Thomas BN, Falade CO, Velavan TP, Ojurongbe O.

Acta Trop. 2019 Aug;196:121-125. doi: 10.1016/j.actatropica.2019.05.016. Epub 2019 May 16.


Distribution of the cytochrome P450 CYP2C8*2 allele in Brazzaville, Republic of Congo.

Peko SM, Ntoumi F, Vouvoungui C, Nderu D, Kobawila SC, Velavan TP, Koukouikila-Koussounda F.

Int J Infect Dis. 2019 Aug;85:49-53. doi: 10.1016/j.ijid.2019.04.035. Epub 2019 May 9.


No expression of HBV-human chimeric fusion transcript (HBx-LINE1) among Vietnamese patients with HBV-associated hepatocellular carcinoma.

Trung NT, Hai LT, Giang DP, Hoan PQ, Binh MT, Hoan NX, Toan NL, Meyer CG, Velavan TP, Bang MH, Song LH.

Ann Hepatol. 2019 Mar - Apr;18(2):404-405. doi: 10.1016/j.aohep.2019.02.002. Epub 2019 Apr 15. No abstract available.


An update on glucose-6-phosphate dehydrogenase deficiency in children from Brazzaville, Republic of Congo.

Gampio Gueye NS, Peko SM, Nderu D, Koukouikila-Koussounda F, Vouvoungui C, Kobawila SC, Velavan TP, Ntoumi F.

Malar J. 2019 Feb 28;18(1):57. doi: 10.1186/s12936-019-2688-z.


Cytochrome P450 CYP2B6*6 distribution among Congolese individuals with HIV, Tuberculosis and Malaria infection.

Peko SM, Gueye NSG, Vouvoungui C, Koukouikila-Koussounda F, Kobawila SC, Nderu D, Velavan TP, Ntoumi F.

Int J Infect Dis. 2019 May;82:111-116. doi: 10.1016/j.ijid.2019.02.025. Epub 2019 Feb 25.


Genetic diversity and population structure of Plasmodium falciparum in Kenyan-Ugandan border areas.

Nderu D, Kimani F, Karanja E, Thiong'o K, Akinyi M, Too E, Chege W, Nambati E, Wangai LN, Meyer CG, Velavan TP.

Trop Med Int Health. 2019 May;24(5):647-656. doi: 10.1111/tmi.13223. Epub 2019 Mar 18.


Plasmodium falciparum histidine-rich protein (PfHRP2 and 3) diversity in Western and Coastal Kenya.

Nderu D, Kimani F, Thiong'o K, Karanja E, Akinyi M, Too E, Chege W, Nambati E, Meyer CG, Velavan TP.

Sci Rep. 2019 Feb 8;9(1):1709. doi: 10.1038/s41598-018-38175-1.


NTCP S267F variant associates with decreased susceptibility to HBV and HDV infection and decelerated progression of related liver diseases.

Binh MT, Hoan NX, Van Tong H, Sy BT, Trung NT, Bock CT, Toan NL, Song LH, Bang MH, Meyer CG, Kremsner PG, Velavan TP.

Int J Infect Dis. 2019 Mar;80:147-152. doi: 10.1016/j.ijid.2019.01.038. Epub 2019 Jan 24.


The blood transcriptome of childhood malaria.

Boldt ABW, van Tong H, Grobusch MP, Kalmbach Y, Dzeing Ella A, Kombila M, Meyer CG, Kun JFJ, Kremsner PG, Velavan TP.

EBioMedicine. 2019 Feb;40:614-625. doi: 10.1016/j.ebiom.2018.12.055. Epub 2019 Jan 10.


Epstein-Barr virus, malaria and endemic Burkitt lymphoma.

Velavan TP.

EBioMedicine. 2019 Jan;39:13-14. doi: 10.1016/j.ebiom.2018.12.041. Epub 2018 Dec 22. No abstract available.


Soluble fibrinogen-like protein 2 levels in patients with hepatitis B virus-related liver diseases.

Van Tong H, Van Ba N, Hoan NX, Binh MT, Quyen DT, Son HA, Van Luong H, Quyet D, Meyer CG, Song LH, Toan NL, Velavan TP.

BMC Infect Dis. 2018 Nov 12;18(1):553. doi: 10.1186/s12879-018-3473-2.


Complement 5a Receptor Polymorphisms Are Associated With Panton-Valentine Leukocidin-positive Staphylococcus aureus Colonization in African Pygmies.

Schaumburg F, Witten A, Flamen A, Stoll M, Alabi AS, Kremsner PG, Löffler B, Zipfel PF, Velavan TP, Peters G.

Clin Infect Dis. 2019 Feb 15;68(5):854-856. doi: 10.1093/cid/ciy666.


PfHRP2-PfHRP3 diversity among Kenyan isolates and comparative evaluation of PfHRP2/pLDH malaria RDT with microscopy and nested PCR methodologies.

Nderu D, Kimani F, Thiong'o K, Akinyi M, Karanja E, Meyer CG, Velavan TP.

Parasitol Int. 2018 Dec;67(6):793-799. doi: 10.1016/j.parint.2018.08.007. Epub 2018 Aug 20.


Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy.

Kretzschmar GC, Oliveira LC, Nisihara RM, Velavan TP, Stinghen ST, Stahlke ERS, Petzl-Erler ML, Messias-Reason IJT, Boldt ABW.

PLoS Negl Trop Dis. 2018 Aug 9;12(8):e0006705. doi: 10.1371/journal.pntd.0006705. eCollection 2018 Aug.


Interferon-stimulated gene 20 kDa protein serum levels and clinical outcome of hepatitis B virus-related liver diseases.

Van Tong H, Hoan NX, Binh MT, Quyen DT, Meyer CG, Song LH, Toan NL, Velavan TP.

Oncotarget. 2018 Jun 12;9(45):27858-27871. doi: 10.18632/oncotarget.25559. eCollection 2018 Jun 12.


HDV infection rates in northern Vietnam.

Binh MT, Hoan NX, Van Tong H, Giang DP, Sy BT, Toan NL, Song LH, Bang MH, Wedemeyer H, Meyer CG, Kremsner PG, Bock CT, Velavan TP.

Sci Rep. 2018 May 23;8(1):8047. doi: 10.1038/s41598-018-26446-w.


Optimisation of quantitative miRNA panels to consolidate the diagnostic surveillance of HBV-related hepatocellular carcinoma.

Tat Trung N, Duong DC, Tong HV, Hien TTT, Hoan PQ, Bang MH, Binh MT, Ky TD, Tung NL, Thinh NT, Sang VV, Thao LTP, Bock CT, Velavan TP, Meyer CG, Song LH, Toan NL.

PLoS One. 2018 Apr 19;13(4):e0196081. doi: 10.1371/journal.pone.0196081. eCollection 2018.


Vitamin D deficiency and hepatitis viruses-associated liver diseases: A literature review.

Hoan NX, Tong HV, Song LH, Meyer CG, Velavan TP.

World J Gastroenterol. 2018 Jan 28;24(4):445-460. doi: 10.3748/wjg.v24.i4.445. Review.


Genetic variants of interferon regulatory factor 5 associated with chronic hepatitis B infection.

Sy BT, Hoan NX, Tong HV, Meyer CG, Toan NL, Song LH, Bock CT, Velavan TP.

World J Gastroenterol. 2018 Jan 14;24(2):248-256. doi: 10.3748/wjg.v24.i2.248.


Silencing of Kangai 1 C-terminal interacting tetraspanin suppresses progression of cholangiocarcinoma.

Bui KC, Barat S, Chen X, Bozko P, Scholta T, Nguyen MLT, Bhuria V, Xing J, Nguyen LT, Le HS, Velavan TP, Sipos B, Wilkens L, Malek NP, Plentz RR.

Exp Cell Res. 2018 Mar 1;364(1):59-67. doi: 10.1016/j.yexcr.2018.01.028. Epub 2018 Jan 31.


Genetic Diversity of the Plasmodium falciparum Glutamate-Rich Protein R2 Region Before and Twelve Years after Introduction of Artemisinin Combination Therapies among Febrile Children in Nigeria.

Nguetse CN, Ojo JA, Nchotebah C, Ikegbunam MN, Meyer CG, Thomas BN, Velavan TP, Ojurongbe O.

Am J Trop Med Hyg. 2018 Mar;98(3):667-676. doi: 10.4269/ajtmh.17-0621. Epub 2018 Jan 18.


Human complement receptor type 1 (CR1) protein levels and genetic variants in chronic Chagas Disease.

Sandri TL, Lidani KCF, Andrade FA, Meyer CG, Kremsner PG, de Messias-Reason IJ, Velavan TP.

Sci Rep. 2018 Jan 11;8(1):526. doi: 10.1038/s41598-017-18937-z.


High prevalence of dihydrofolate reductase gene mutations in Plasmodium falciparum parasites among pregnant women in Nigeria after reported use of sulfadoxine-pyrimethamine.

Ojurongbe O, Nguetse CN, Fayemiwo SA, Falade CO, Ojurongbe TA, Thomas BN, Meyer CG, Velavan TP.

Pathog Glob Health. 2018 Mar;112(2):86-92. doi: 10.1080/20477724.2017.1422615. Epub 2018 Jan 10.


Efficacy and Safety of Fosmidomycin-Piperaquine as Nonartemisinin-Based Combination Therapy for Uncomplicated Falciparum Malaria: A Single-Arm, Age De-escalation Proof-of-Concept Study in Gabon.

Mombo-Ngoma G, Remppis J, Sievers M, Zoleko Manego R, Endamne L, Kabwende L, Veletzky L, Nguyen TT, Groger M, Lötsch F, Mischlinger J, Flohr L, Kim J, Cattaneo C, Hutchinson D, Duparc S, Moehrle J, Velavan TP, Lell B, Ramharter M, Adegnika AA, Mordmüller B, Kremsner PG.

Clin Infect Dis. 2018 Jun 1;66(12):1823-1830. doi: 10.1093/cid/cix1122.


KIR-HLA distribution in a Vietnamese population from Hanoi.

Amorim LM, van Tong H, Hoan NX, Vargas LB, Ribeiro EMSF, Petzl-Erler ML, Boldt ABW, Toan NL, Song LH, Velavan TP, Augusto DG.

Hum Immunol. 2018 Feb;79(2):93-100. doi: 10.1016/j.humimm.2017.11.011. Epub 2017 Nov 27.


Differential contribution of interleukin-10 promoter variants in malaria and schistosomiasis mono- and co-infections among Nigerian children.

Adedoja A, Hoan NX, van Tong H, Adukpo S, Tijani DB, Akanbi AA 2nd, Meyer CG, Ojurongbe O, Velavan TP.

Trop Med Int Health. 2018 Jan;23(1):45-52. doi: 10.1111/tmi.13007. Epub 2017 Nov 24.


Mannose-binding lectin deficiency and miscarriages in rheumatoid arthritis.

Cieslinski JZ, Goeldner I, Skare TL, Nisihara R, Andrade FA, Velavan TP, Messias-Reason I, Utiyama SRR.

Autoimmunity. 2017 Nov;50(7):409-413. doi: 10.1080/08916934.2017.1373765. Epub 2017 Sep 12.


Human genetic factors in tuberculosis: an update.

van Tong H, Velavan TP, Thye T, Meyer CG.

Trop Med Int Health. 2017 Sep;22(9):1063-1071. doi: 10.1111/tmi.12923. Epub 2017 Jul 19. Review.


Pyruvate Kinase and Fcγ Receptor Gene Copy Numbers Associated With Malaria Phenotypes.

Faik I, van Tong H, Lell B, Meyer CG, Kremsner PG, Velavan TP.

J Infect Dis. 2017 Jul 15;216(2):276-282. doi: 10.1093/infdis/jix284.


Molecular markers of anti-malarial drug resistance in Central, West and East African children with severe malaria.

Nguetse CN, Adegnika AA, Agbenyega T, Ogutu BR, Krishna S, Kremsner PG, Velavan TP.

Malar J. 2017 May 23;16(1):217. doi: 10.1186/s12936-017-1868-y.


Geographical distribution of complement receptor type 1 variants and their associated disease risk.

Lucas Sandri T, Adukpo S, Giang DP, Nguetse CN, Antunes Andrade F, Tong HV, Toan NL, Song LH, Elumalai P, Thangaraj K, Valluri VL, Ntoumi F, Meyer CG, Jose de Messias Reason I, Kremsner PG, Velavan TP.

PLoS One. 2017 May 17;12(5):e0175973. doi: 10.1371/journal.pone.0175973. eCollection 2017.


Molecular surveillance of Plasmodium falciparum drug resistance in the Republic of Congo: four and nine years after the introduction of artemisinin-based combination therapy.

Koukouikila-Koussounda F, Jeyaraj S, Nguetse CN, Nkonganyi CN, Kokou KC, Etoka-Beka MK, Ntoumi F, Velavan TP.

Malar J. 2017 Apr 19;16(1):155. doi: 10.1186/s12936-017-1816-x.


Prevalence and genotype distribution of hepatitis delta virus among chronic hepatitis B carriers in Central Vietnam.

Nguyen HM, Sy BT, Trung NT, Hoan NX, Wedemeyer H, Velavan TP, Bock CT.

PLoS One. 2017 Apr 12;12(4):e0175304. doi: 10.1371/journal.pone.0175304. eCollection 2017.


SOCS3 genetic variants and promoter hypermethylation in patients with chronic hepatitis B.

Hoan NX, Van Tong H, Giang DP, Cuong BK, Toan NL, Wedemeyer H, Bock CT, Kremsner PG, Song LH, Velavan TP.

Oncotarget. 2017 Mar 7;8(10):17127-17139. doi: 10.18632/oncotarget.15083.


Parasite Infection, Carcinogenesis and Human Malignancy.

van Tong H, Brindley PJ, Meyer CG, Velavan TP.

EBioMedicine. 2017 Feb;15:12-23. doi: 10.1016/j.ebiom.2016.11.034. Epub 2016 Dec 2. Review.


Adiponectin and pro-inflammatory cytokines are modulated in Vietnamese patients with type 2 diabetes mellitus.

Tong HV, Luu NK, Son HA, Hoan NV, Hung TT, Velavan TP, Toan NL.

J Diabetes Investig. 2017 May;8(3):295-305. doi: 10.1111/jdi.12579. Epub 2016 Oct 30.


Triggering receptor expressed on myeloid cells 1 (TREM-1) and cytokine gene variants in complicated and uncomplicated malaria.

Adukpo S, Gyan BA, Ofori MF, Dodoo D, Velavan TP, Meyer CG.

Trop Med Int Health. 2016 Dec;21(12):1592-1601. doi: 10.1111/tmi.12787. Epub 2016 Oct 24.


Association of vitamin D deficiency with hepatitis B virus - related liver diseases.

Hoan NX, Khuyen N, Binh MT, Giang DP, Van Tong H, Hoan PQ, Trung NT, Anh DT, Toan NL, Meyer CG, Kremsner PG, Velavan TP, Song LH.

BMC Infect Dis. 2016 Sep 23;16(1):507.


Interferon-stimulated gene 15 in hepatitis B-related liver diseases.

Hoan NX, Van Tong H, Giang DP, Toan NL, Meyer CG, Bock CT, Kremsner PG, Song LH, Velavan TP.

Oncotarget. 2016 Oct 18;7(42):67777-67787. doi: 10.18632/oncotarget.11955.

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