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Items: 32

1.

Corrigendum: Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury.

Velardi E, Tsai JJ, Radtke S, Cooper K, Argyropoulos KV, Jae-Hung S, Young LF, Lazrak A, Smith OM, Lieberman S, Kreines F, Shono Y, Wertheimer T, Jenq RR, Hanash AM, Narayan P, Lei Z, Moore MA, Kiem HP, van den Brink MRM, Dudakov JA.

Nat Med. 2018 Apr 10;24(4):525. doi: 10.1038/nm0418-525b.

PMID:
29634695
2.

Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice.

Staffas A, Burgos da Silva M, Slingerland AE, Lazrak A, Bare CJ, Holman CD, Docampo MD, Shono Y, Durham B, Pickard AJ, Cross JR, Stein-Thoeringer C, Velardi E, Tsai JJ, Jahn L, Jay H, Lieberman S, Smith OM, Pamer EG, Peled JU, Cohen DE, Jenq RR, van den Brink MRM.

Cell Host Microbe. 2018 Apr 11;23(4):447-457.e4. doi: 10.1016/j.chom.2018.03.002. Epub 2018 Mar 22.

PMID:
29576480
3.

Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.

Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P, Kinsella S, Palikuqi B, Ginsberg M, Young LF, Kreines F, Lieberman SR, Lazrak A, Guo P, Malard F, Smith OM, Shono Y, Jenq RR, Hanash AM, Nolan DJ, Butler JM, Beilhack A, Manley NR, Rafii S, Dudakov JA, van den Brink MRM.

Sci Immunol. 2018 Jan 12;3(19). pii: eaal2736. doi: 10.1126/sciimmunol.aal2736.

4.

Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury.

Velardi E, Tsai JJ, Radtke S, Cooper K, Argyropoulos KV, Jae-Hung S, Young LF, Lazrak A, Smith OM, Lieberman S, Kreines F, Shono Y, Wertheimer T, Jenq RR, Hanash AM, Narayan P, Lei Z, Moore MA, Kiem HP, van den Brink MRM, Dudakov JA.

Nat Med. 2018 Feb;24(2):239-246. doi: 10.1038/nm.4470. Epub 2018 Jan 8. Erratum in: Nat Med. 2018 Apr 10;24(4):525.

5.

Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease.

Dudakov JA, Mertelsmann AM, O'Connor MH, Jenq RR, Velardi E, Young LF, Smith OM, Boyd RL, van den Brink MRM, Hanash AM.

Blood. 2017 Aug 17;130(7):933-942. doi: 10.1182/blood-2017-01-762658. Epub 2017 Jun 12.

PMID:
28607133
6.

RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury.

Fischer JC, Bscheider M, Eisenkolb G, Lin CC, Wintges A, Otten V, Lindemans CA, Heidegger S, Rudelius M, Monette S, Porosnicu Rodriguez KA, Calafiore M, Liebermann S, Liu C, Lienenklaus S, Weiss S, Kalinke U, Ruland J, Peschel C, Shono Y, Docampo M, Velardi E, Jenq RR, Hanash AM, Dudakov JA, Haas T, van den Brink MRM, Poeck H.

Sci Transl Med. 2017 Apr 19;9(386). pii: eaag2513. doi: 10.1126/scitranslmed.aag2513.

7.

Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity.

Ghosh A, Smith M, James SE, Davila ML, Velardi E, Argyropoulos KV, Gunset G, Perna F, Kreines FM, Levy ER, Lieberman S, Jay HV, Tuckett AZ, Zakrzewski JL, Tan L, Young LF, Takvorian K, Dudakov JA, Jenq RR, Hanash AM, Motta AC, Murphy GF, Liu C, Schietinger A, Sadelain M, van den Brink MR.

Nat Med. 2017 Feb;23(2):242-249. doi: 10.1038/nm.4258. Epub 2017 Jan 9.

8.

Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation: Time To T Up the Thymus.

Chaudhry MS, Velardi E, Malard F, van den Brink MR.

J Immunol. 2017 Jan 1;198(1):40-46. Review.

9.

Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice.

Shono Y, Docampo MD, Peled JU, Perobelli SM, Velardi E, Tsai JJ, Slingerland AE, Smith OM, Young LF, Gupta J, Lieberman SR, Jay HV, Ahr KF, Porosnicu Rodriguez KA, Xu K, Calarfiore M, Poeck H, Caballero S, Devlin SM, Rapaport F, Dudakov JA, Hanash AM, Gyurkocza B, Murphy GF, Gomes C, Liu C, Moss EL, Falconer SB, Bhatt AS, Taur Y, Pamer EG, van den Brink MRM, Jenq RR.

Sci Transl Med. 2016 May 18;8(339):339ra71. doi: 10.1126/scitranslmed.aaf2311.

10.

Thymus: the next (re)generation.

Chaudhry MS, Velardi E, Dudakov JA, van den Brink MR.

Immunol Rev. 2016 May;271(1):56-71. doi: 10.1111/imr.12418. Review.

11.

Clonal B cells in Waldenström's macroglobulinemia exhibit functional features of chronic active B-cell receptor signaling.

Argyropoulos KV, Vogel R, Ziegler C, Altan-Bonnet G, Velardi E, Calafiore M, Dogan A, Arcila M, Patel M, Knapp K, Mallek C, Hunter ZR, Treon SP, van den Brink MR, Palomba ML.

Leukemia. 2016 May;30(5):1116-25. doi: 10.1038/leu.2016.8. Epub 2016 Feb 12.

12.

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration.

Lindemans CA, Calafiore M, Mertelsmann AM, O'Connor MH, Dudakov JA, Jenq RR, Velardi E, Young LF, Smith OM, Lawrence G, Ivanov JA, Fu YY, Takashima S, Hua G, Martin ML, O'Rourke KP, Lo YH, Mokry M, Romera-Hernandez M, Cupedo T, Dow L, Nieuwenhuis EE, Shroyer NF, Liu C, Kolesnick R, van den Brink MRM, Hanash AM.

Nature. 2015 Dec 24;528(7583):560-564. doi: 10.1038/nature16460. Epub 2015 Dec 9.

13.

Immune reconstitution following stem cell transplantation.

van den Brink MR, Velardi E, Perales MA.

Hematology Am Soc Hematol Educ Program. 2015;2015:215-9. doi: 10.1182/asheducation-2015.1.215. No abstract available.

PMID:
26637724
14.

Sex steroid ablation: an immunoregenerative strategy for immunocompromised patients.

Velardi E, Dudakov JA, van den Brink MR.

Bone Marrow Transplant. 2015 Jun;50 Suppl 2:S77-81. doi: 10.1038/bmt.2015.101. Review.

15.

Sex steroid blockade enhances thymopoiesis by modulating Notch signaling.

Velardi E, Tsai JJ, Holland AM, Wertheimer T, Yu VW, Zakrzewski JL, Tuckett AZ, Singer NV, West ML, Smith OM, Young LF, Kreines FM, Levy ER, Boyd RL, Scadden DT, Dudakov JA, van den Brink MR.

J Exp Med. 2014 Nov 17;211(12):2341-9. doi: 10.1084/jem.20131289. Epub 2014 Oct 20.

16.

WNT signaling suppression in the senescent human thymus.

Ferrando-Martínez S, Ruiz-Mateos E, Dudakov JA, Velardi E, Grillari J, Kreil DP, Muñoz-Fernandez MÁ, van den Brink MR, Leal M.

J Gerontol A Biol Sci Med Sci. 2015 Mar;70(3):273-81. doi: 10.1093/gerona/glu030. Epub 2014 Mar 22.

17.

Clinical strategies to enhance thymic recovery after allogeneic hematopoietic stem cell transplantation.

Velardi E, Dudakov JA, van den Brink MR.

Immunol Lett. 2013 Sep-Oct;155(1-2):31-5. doi: 10.1016/j.imlet.2013.09.016. Epub 2013 Oct 8. Review.

18.

Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity.

Ghosh A, Dogan Y, Moroz M, Holland AM, Yim NL, Rao UK, Young LF, Tannenbaum D, Masih D, Velardi E, Tsai JJ, Jenq RR, Penack O, Hanash AM, Smith OM, Piersanti K, Lezcano C, Murphy GF, Liu C, Palomba ML, Sauer MG, Sadelain M, Ponomarev V, van den Brink MR.

J Clin Invest. 2013 Jun;123(6):2654-62. doi: 10.1172/JCI66301. Epub 2013 May 15.

19.

Nrf2 regulates haematopoietic stem cell function.

Tsai JJ, Dudakov JA, Takahashi K, Shieh JH, Velardi E, Holland AM, Singer NV, West ML, Smith OM, Young LF, Shono Y, Ghosh A, Hanash AM, Tran HT, Moore MA, van den Brink MR.

Nat Cell Biol. 2013 Mar;15(3):309-16. doi: 10.1038/ncb2699. Epub 2013 Feb 24.

20.

Reduction of ischemic brain injury by administration of palmitoylethanolamide after transient middle cerebral artery occlusion in rats.

Ahmad A, Genovese T, Impellizzeri D, Crupi R, Velardi E, Marino A, Esposito E, Cuzzocrea S.

Brain Res. 2012 Oct 5;1477:45-58. doi: 10.1016/j.brainres.2012.08.006. Epub 2012 Aug 13.

PMID:
23046519
21.

Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease.

Hanash AM, Dudakov JA, Hua G, O'Connor MH, Young LF, Singer NV, West ML, Jenq RR, Holland AM, Kappel LW, Ghosh A, Tsai JJ, Rao UK, Yim NL, Smith OM, Velardi E, Hawryluk EB, Murphy GF, Liu C, Fouser LA, Kolesnick R, Blazar BR, van den Brink MR.

Immunity. 2012 Aug 24;37(2):339-50. doi: 10.1016/j.immuni.2012.05.028.

22.

Palmitoylethanolamide reduces early renal dysfunction and injury caused by experimental ischemia and reperfusion in mice.

Di Paola R, Impellizzeri D, Mondello P, Velardi E, Aloisi C, Cappellani A, Esposito E, Cuzzocrea S.

Shock. 2012 Oct;38(4):356-66.

PMID:
22772472
23.

Glucocorticoid-induced leucine zipper (GILZ) over-expression in T lymphocytes inhibits inflammation and tissue damage in spinal cord injury.

Esposito E, Bruscoli S, Mazzon E, Paterniti I, Coppo M, Velardi E, Cuzzocrea S, Riccardi C.

Neurotherapeutics. 2012 Jan;9(1):210-25. doi: 10.1007/s13311-011-0084-7.

24.

Long glucocorticoid-induced leucine zipper (L-GILZ) protein interacts with ras protein pathway and contributes to spermatogenesis control.

Bruscoli S, Velardi E, Di Sante M, Bereshchenko O, Venanzi A, Coppo M, Berno V, Mameli MG, Colella R, Cavaliere A, Riccardi C.

J Biol Chem. 2012 Jan 6;287(2):1242-51. doi: 10.1074/jbc.M111.316372. Epub 2011 Nov 22.

25.

Glucocorticoid-induced activation of caspase-8 protects the glucocorticoid-induced protein Gilz from proteasomal degradation and induces its binding to SUMO-1 in murine thymocytes.

Delfino DV, Spinicelli S, Pozzesi N, Pierangeli S, Velardi E, Bruscoli S, Martelli MP, Pettirossi V, Falchi L, Kang TB, Riccardi C.

Cell Death Differ. 2011 Jan;18(1):183-90. doi: 10.1038/cdd.2010.86. Epub 2010 Jul 30.

26.

Glucocorticoid-induced leucine zipper (GILZ) and long GILZ inhibit myogenic differentiation and mediate anti-myogenic effects of glucocorticoids.

Bruscoli S, Donato V, Velardi E, Di Sante M, Migliorati G, Donato R, Riccardi C.

J Biol Chem. 2010 Apr 2;285(14):10385-96. doi: 10.1074/jbc.M109.070136. Epub 2010 Feb 2.

27.

Silymarin suppress CD4+ T cell activation and proliferation: effects on NF-kappaB activity and IL-2 production.

Gharagozloo M, Velardi E, Bruscoli S, Agostini M, Di Sante M, Donato V, Amirghofran Z, Riccardi C.

Pharmacol Res. 2010 May;61(5):405-9. doi: 10.1016/j.phrs.2009.12.017. Epub 2010 Jan 7.

PMID:
20056147
28.

Involvement of cPLA2 inhibition in dexamethasone-induced thymocyte apoptosis.

Cinque B, Fanini D, Di Marzio L, Palumbo P, La Torre C, Donato V, Velardi E, Bruscoli S, Riccardi C, Cifone MG.

Int J Immunopathol Pharmacol. 2008 Jul-Sep;21(3):539-51.

PMID:
18831921
29.

Peroxisome proliferator-activated receptor-alpha contributes to the anti-inflammatory activity of glucocorticoids.

Cuzzocrea S, Bruscoli S, Mazzon E, Crisafulli C, Donato V, Di Paola R, Velardi E, Esposito E, Nocentini G, Riccardi C.

Mol Pharmacol. 2008 Feb;73(2):323-37. Epub 2007 Nov 5.

30.

Glucocorticoid-induced leucine zipper (GILZ)/NF-kappaB interaction: role of GILZ homo-dimerization and C-terminal domain.

Di Marco B, Massetti M, Bruscoli S, Macchiarulo A, Di Virgilio R, Velardi E, Donato V, Migliorati G, Riccardi C.

Nucleic Acids Res. 2007;35(2):517-28. Epub 2006 Dec 14.

31.

Toward the identification of a tolerogenic signature in IDO-competent dendritic cells.

Orabona C, Puccetti P, Vacca C, Bicciato S, Luchini A, Fallarino F, Bianchi R, Velardi E, Perruccio K, Velardi A, Bronte V, Fioretti MC, Grohmann U.

Blood. 2006 Apr 1;107(7):2846-54. Epub 2005 Dec 8. Erratum in: Blood. 2006 May 1;107(9):3441.

32.

Genomic and non-genomic effects of different glucocorticoids on mouse thymocyte apoptosis.

Bruscoli S, Di Virgilio R, Donato V, Velardi E, Baldoni M, Marchetti C, Migliorati G, Riccardi C.

Eur J Pharmacol. 2006 Jan 4;529(1-3):63-70. Epub 2005 Dec 1.

PMID:
16325174

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