Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 116


Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders.

Hjelm BE, Rollins B, Morgan L, Sequeira A, Mamdani F, Pereira F, Damas J, Webb MG, Weber MD, Schatzberg AF, Barchas JD, Lee FS, Akil H, Watson SJ, Myers RM, Chao EC, Kimonis V, Thompson PM, Bunney WE, Vawter MP.

Nucleic Acids Res. 2019 Mar 14. pii: gkz164. doi: 10.1093/nar/gkz164. [Epub ahead of print]


Inference of cell type content from human brain transcriptomic datasets illuminates the effects of age, manner of death, dissection, and psychiatric diagnosis.

Hagenauer MH, Schulmann A, Li JZ, Vawter MP, Walsh DM, Thompson RC, Turner CA, Bunney WE, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H.

PLoS One. 2018 Jul 17;13(7):e0200003. doi: 10.1371/journal.pone.0200003. eCollection 2018.


Exon Array Biomarkers for the Differential Diagnosis of Schizophrenia and Bipolar Disorder.

Vawter MP, Philibert R, Rollins B, Ruppel PL, Osborn TW.

Mol Neuropsychiatry. 2018 May;3(4):197-213. doi: 10.1159/000485800. Epub 2018 Apr 10.


Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses.

Rajamani U, Gross AR, Hjelm BE, Sequeira A, Vawter MP, Tang J, Gangalapudi V, Wang Y, Andres AM, Gottlieb RA, Sareen D.

Cell Stem Cell. 2018 May 3;22(5):698-712.e9. doi: 10.1016/j.stem.2018.03.009. Epub 2018 Apr 19.


A Comprehensive Analysis of Nuclear-Encoded Mitochondrial Genes in Schizophrenia.

Gonçalves VF, Cappi C, Hagen CM, Sequeira A, Vawter MP, Derkach A, Zai CC, Hedley PL, Bybjerg-Grauholm J, Pouget JG, Cuperfain AB, Sullivan PF, Christiansen M, Kennedy JL, Sun L.

Biol Psychiatry. 2018 May 1;83(9):780-789. doi: 10.1016/j.biopsych.2018.02.1175. Epub 2018 Mar 15.


Mitochondrial Complex I Deficiency in Schizophrenia and Bipolar Disorder and Medication Influence.

Rollins BL, Morgan L, Hjelm BE, Sequeira A, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Potkin SG, Bunney WE, Vawter MP.

Mol Neuropsychiatry. 2018 Feb;3(3):157-169. doi: 10.1159/000484348. Epub 2017 Nov 30.


A Genome-Wide Search for Bipolar Disorder Risk Loci Modified by Mitochondrial Genome Variation.

Ryu E, Nassan M, Jenkins GD, Armasu SM, Andreazza A, McElroy SL, Vawter MP, Frye MA, Biernacka JM.

Mol Neuropsychiatry. 2018 Feb;3(3):125-134. doi: 10.1159/000464444. Epub 2017 Oct 28.


Examining the role of common and rare mitochondrial variants in schizophrenia.

Gonçalves VF, Giamberardino SN, Crowley JJ, Vawter MP, Saxena R, Bulik CM, Yilmaz Z, Hultman CM, Sklar P, Kennedy JL, Sullivan PF, Knight J.

PLoS One. 2018 Jan 25;13(1):e0191153. doi: 10.1371/journal.pone.0191153. eCollection 2018.


Post-mortem molecular profiling of three psychiatric disorders.

Ramaker RC, Bowling KM, Lasseigne BN, Hagenauer MH, Hardigan AA, Davis NS, Gertz J, Cartagena PM, Walsh DM, Vawter MP, Jones EG, Schatzberg AF, Barchas JD, Watson SJ, Bunney BG, Akil H, Bunney WE, Li JZ, Cooper SJ, Myers RM.

Genome Med. 2017 Jul 28;9(1):72. doi: 10.1186/s13073-017-0458-5.


A comprehensive analysis of mitochondrial genes variants and their association with antipsychotic-induced weight gain.

Mittal K, Gonçalves VF, Harripaul R, Cuperfain AB, Rollins B, Tiwari AK, Zai CC, Maciukiewicz M, Müller DJ, Vawter MP, Kennedy JL.

Schizophr Res. 2017 Sep;187:67-73. doi: 10.1016/j.schres.2017.06.046. Epub 2017 Jul 8.


A Circadian Genomic Signature Common to Ketamine and Sleep Deprivation in the Anterior Cingulate Cortex.

Orozco-Solis R, Montellier E, Aguilar-Arnal L, Sato S, Vawter MP, Bunney BG, Bunney WE, Sassone-Corsi P.

Biol Psychiatry. 2017 Sep 1;82(5):351-360. doi: 10.1016/j.biopsych.2017.02.1176. Epub 2017 Mar 1.


Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder.

Mamdani F, Rollins B, Morgan L, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Potkin SG, Bunney WE, Vawter MP, Sequeira PA.

Transl Psychiatry. 2016 Dec 6;6(12):e969. doi: 10.1038/tp.2015.164. No abstract available.


Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission.

Limon A, Mamdani F, Hjelm BE, Vawter MP, Sequeira A.

Neurosci Biobehav Rev. 2016 Jul;66:80-91. doi: 10.1016/j.neubiorev.2016.04.010. Epub 2016 Apr 22. Review.


Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders.

Morgan LZ, Rollins B, Sequeira A, Byerley W, DeLisi LE, Schatzberg AF, Barchas JD, Myers RM, Watson SJ, Akil H, Bunney WE Jr, Vawter MP.

Microarrays (Basel). 2016 Mar;5(1). pii: 6. Epub 2016 Mar 7.


Increased Energy Expenditure, Ucp1 Expression, and Resistance to Diet-induced Obesity in Mice Lacking Nuclear Factor-Erythroid-2-related Transcription Factor-2 (Nrf2).

Schneider K, Valdez J, Nguyen J, Vawter M, Galke B, Kurtz TW, Chan JY.

J Biol Chem. 2016 Apr 1;291(14):7754-66. doi: 10.1074/jbc.M115.673756. Epub 2016 Feb 3.


A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder.

Sellgren CM, Kegel ME, Bergen SE, Ekman CJ, Olsson S, Larsson M, Vawter MP, Backlund L, Sullivan PF, Sklar P, Smoller JW, Magnusson PK, Hultman CM, Walther-Jallow L, Svensson CI, Lichtenstein P, Schalling M, Engberg G, Erhardt S, Landén M.

Mol Psychiatry. 2016 Oct;21(10):1342-50. doi: 10.1038/mp.2015.186. Epub 2015 Dec 15.


Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia.

Hjelm BE, Rollins B, Mamdani F, Lauterborn JC, Kirov G, Lynch G, Gall CM, Sequeira A, Vawter MP.

Mol Neuropsychiatry. 2015 Dec;1(4):201-19. doi: 10.1159/000441252. Epub 2015 Oct 28. Review. Erratum in: Mol Neuropsychiatry. 2016 May;2(1):60.


Olanzapine Reversed Brain Gene Expression Changes Induced by Phencyclidine Treatment in Non-Human Primates.

Martin MV, Mirnics K, Nisenbaum LK, Vawter MP.

Mol Neuropsychiatry. 2015 Jul;1(2):82-93.


Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder.

Mamdani F, Rollins B, Morgan L, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Potkin SG, Bunney WE, Vawter MP, Sequeira PA.

Transl Psychiatry. 2015 Sep 15;5:e636. doi: 10.1038/tp.2015.134. Erratum in: Transl Psychiatry. 2016 Dec 6;6(12 ):e969.


Mitochondrial mutations in subjects with psychiatric disorders.

Sequeira A, Rollins B, Magnan C, van Oven M, Baldi P, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Bunney WE, Vawter MP.

PLoS One. 2015 May 26;10(5):e0127280. doi: 10.1371/journal.pone.0127280. eCollection 2015.


Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder.

Bunney BG, Li JZ, Walsh DM, Stein R, Vawter MP, Cartagena P, Barchas JD, Schatzberg AF, Myers RM, Watson SJ, Akil H, Bunney WE.

Mol Psychiatry. 2015 Feb;20(1):48-55. doi: 10.1038/mp.2014.138. Epub 2014 Nov 4. Review.


The somatic common deletion in mitochondrial DNA is decreased in schizophrenia.

Mamdani F, Rollins B, Morgan L, Sequeira PA, Vawter MP.

Schizophr Res. 2014 Nov;159(2-3):370-5. doi: 10.1016/j.schres.2014.08.026. Epub 2014 Sep 28.


Identification of pathways for bipolar disorder: a meta-analysis.

Nurnberger JI Jr, Koller DL, Jung J, Edenberg HJ, Foroud T, Guella I, Vawter MP, Kelsoe JR; Psychiatric Genomics Consortium Bipolar Group.

JAMA Psychiatry. 2014 Jun;71(6):657-64. doi: 10.1001/jamapsychiatry.2014.176.


Inherited mitochondrial DNA variants can affect complement, inflammation and apoptosis pathways: insights into mitochondrial-nuclear interactions.

Kenney MC, Chwa M, Atilano SR, Falatoonzadeh P, Ramirez C, Malik D, Tarek M, Cáceres-del-Carpio J, Nesburn AB, Boyer DS, Kuppermann BD, Vawter M, Jazwinski SM, Miceli M, Wallace DC, Udar N.

Hum Mol Genet. 2014 Jul 1;23(13):3537-51. doi: 10.1093/hmg/ddu065. Epub 2014 Feb 28.


Allelic imbalance associated with the schizophrenia risk SNP rs1344706 indicates a cis-acting variant in ZNF804A.

Guella I, Vawter MP.

Schizophr Res. 2014 Mar;153(1-3):243-5. doi: 10.1016/j.schres.2014.01.005. Epub 2014 Jan 23. No abstract available.


A splice donor mutation in NAA10 results in the dysregulation of the retinoic acid signalling pathway and causes Lenz microphthalmia syndrome.

Esmailpour T, Riazifar H, Liu L, Donkervoort S, Huang VH, Madaan S, Shoucri BM, Busch A, Wu J, Towbin A, Chadwick RB, Sequeira A, Vawter MP, Sun G, Johnston JJ, Biesecker LG, Kawaguchi R, Sun H, Kimonis V, Huang T.

J Med Genet. 2014 Mar;51(3):185-96. doi: 10.1136/jmedgenet-2013-101660. Epub 2014 Jan 15.


G protein-linked signaling pathways in bipolar and major depressive disorders.

Tomita H, Ziegler ME, Kim HB, Evans SJ, Choudary PV, Li JZ, Meng F, Dai M, Myers RM, Neal CR, Speed TP, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Jones EG, Bunney WE, Vawter MP.

Front Genet. 2013 Dec 23;4:297. doi: 10.3389/fgene.2013.00297. eCollection 2013.


Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex.

Guella I, Sequeira A, Rollins B, Morgan L, Myers RM, Watson SJ, Akil H, Bunney WE, Delisi LE, Byerley W, Vawter MP.

Schizophr Res. 2014 Jan;152(1):111-6. doi: 10.1016/j.schres.2013.11.021. Epub 2013 Dec 7.


Peripheral biomarkers revisited: integrative profiling of peripheral samples for psychiatric research.

Hayashi-Takagi A, Vawter MP, Iwamoto K.

Biol Psychiatry. 2014 Jun 15;75(12):920-8. doi: 10.1016/j.biopsych.2013.09.035. Epub 2013 Oct 18. Review.


Molecular and bioenergetic differences between cells with African versus European inherited mitochondrial DNA haplogroups: implications for population susceptibility to diseases.

Kenney MC, Chwa M, Atilano SR, Falatoonzadeh P, Ramirez C, Malik D, Tarek M, Del Carpio JC, Nesburn AB, Boyer DS, Kuppermann BD, Vawter MP, Jazwinski SM, Miceli MV, Wallace DC, Udar N.

Biochim Biophys Acta. 2014 Feb;1842(2):208-19. doi: 10.1016/j.bbadis.2013.10.016. Epub 2013 Nov 4.


Coding and noncoding gene expression biomarkers in mood disorders and schizophrenia.

Mamdani F, Martin MV, Lencz T, Rollins B, Robinson DG, Moon EA, Malhotra AK, Vawter MP.

Dis Markers. 2013;35(1):11-21. doi: 10.1155/2013/748095. Epub 2013 Jul 21. Review.


Schizophrenia miR-137 locus risk genotype is associated with dorsolateral prefrontal cortex hyperactivation.

van Erp TG, Guella I, Vawter MP, Turner J, Brown GG, McCarthy G, Greve DN, Glover GH, Calhoun VD, Lim KO, Bustillo JR, Belger A, Ford JM, Mathalon DH, Diaz M, Preda A, Nguyen D, Macciardi F, Potkin SG.

Biol Psychiatry. 2014 Mar 1;75(5):398-405. doi: 10.1016/j.biopsych.2013.06.016. Epub 2013 Aug 1.


Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia.

Bharadwaj R, Jiang Y, Mao W, Jakovcevski M, Dincer A, Krueger W, Garbett K, Whittle C, Tushir JS, Liu J, Sequeira A, Vawter MP, Gardner PD, Casaccia P, Rasmussen T, Bunney WE Jr, Mirnics K, Futai K, Akbarian S.

J Neurosci. 2013 Jul 17;33(29):11839-51. doi: 10.1523/JNEUROSCI.1252-13.2013.


Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex.

Guella I, Sequeira A, Rollins B, Morgan L, Torri F, van Erp TG, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Bunney WE, Potkin SG, Macciardi F, Vawter MP.

J Psychiatr Res. 2013 Sep;47(9):1215-21. doi: 10.1016/j.jpsychires.2013.05.021. Epub 2013 Jun 17.


Circadian patterns of gene expression in the human brain and disruption in major depressive disorder.

Li JZ, Bunney BG, Meng F, Hagenauer MH, Walsh DM, Vawter MP, Evans SJ, Choudary PV, Cartagena P, Barchas JD, Schatzberg AF, Jones EG, Myers RM, Watson SJ Jr, Akil H, Bunney WE.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9950-5. doi: 10.1073/pnas.1305814110. Epub 2013 May 13.


Increased CNV-region deletions in mild cognitive impairment (MCI) and Alzheimer's disease (AD) subjects in the ADNI sample.

Guffanti G, Torri F, Rasmussen J, Clark AP, Lakatos A, Turner JA, Fallon JH, Saykin AJ, Weiner M; ADNI the Alzheimer's Disease Neuroimaging Initiative, Vawter MP, Knowles JA, Potkin SG, Macciardi F.

Genomics. 2013 Aug;102(2):112-22. doi: 10.1016/j.ygeno.2013.04.004. Epub 2013 Apr 11.


The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression.

Lavebratt C, Olsson S, Backlund L, Frisén L, Sellgren C, Priebe L, Nikamo P, Träskman-Bendz L, Cichon S, Vawter MP, Osby U, Engberg G, Landén M, Erhardt S, Schalling M.

Mol Psychiatry. 2014 Mar;19(3):334-41. doi: 10.1038/mp.2013.11. Epub 2013 Mar 5.


Next generation sequence analysis and computational genomics using graphical pipeline workflows.

Torri F, Dinov ID, Zamanyan A, Hobel S, Genco A, Petrosyan P, Clark AP, Liu Z, Eggert P, Pierce J, Knowles JA, Ames J, Kesselman C, Toga AW, Potkin SG, Vawter MP, Macciardi F.

Genes (Basel). 2012 Aug 30;3(3):545-75. doi: 10.3390/genes3030545.


An anatomically comprehensive atlas of the adult human brain transcriptome.

Hawrylycz MJ, Lein ES, Guillozet-Bongaarts AL, Shen EH, Ng L, Miller JA, van de Lagemaat LN, Smith KA, Ebbert A, Riley ZL, Abajian C, Beckmann CF, Bernard A, Bertagnolli D, Boe AF, Cartagena PM, Chakravarty MM, Chapin M, Chong J, Dalley RA, David Daly B, Dang C, Datta S, Dee N, Dolbeare TA, Faber V, Feng D, Fowler DR, Goldy J, Gregor BW, Haradon Z, Haynor DR, Hohmann JG, Horvath S, Howard RE, Jeromin A, Jochim JM, Kinnunen M, Lau C, Lazarz ET, Lee C, Lemon TA, Li L, Li Y, Morris JA, Overly CC, Parker PD, Parry SE, Reding M, Royall JJ, Schulkin J, Sequeira PA, Slaughterbeck CR, Smith SC, Sodt AJ, Sunkin SM, Swanson BE, Vawter MP, Williams D, Wohnoutka P, Zielke HR, Geschwind DH, Hof PR, Smith SM, Koch C, Grant SGN, Jones AR.

Nature. 2012 Sep 20;489(7416):391-399. doi: 10.1038/nature11405.


P2RX7: expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1.

Backlund L, Lavebratt C, Frisén L, Nikamo P, Hukic Sudic D, Träskman-Bendz L, Landén M, Edman G, Vawter MP, Ösby U, Schalling M.

PLoS One. 2012;7(8):e43057. doi: 10.1371/journal.pone.0043057. Epub 2012 Aug 28.


Mitochondrial mutations and polymorphisms in psychiatric disorders.

Sequeira A, Martin MV, Rollins B, Moon EA, Bunney WE, Macciardi F, Lupoli S, Smith EN, Kelsoe J, Magnan CN, van Oven M, Baldi P, Wallace DC, Vawter MP.

Front Genet. 2012 Jun 20;3:103. doi: 10.3389/fgene.2012.00103. eCollection 2012.


Gene expression changes in the prefrontal cortex, anterior cingulate cortex and nucleus accumbens of mood disorders subjects that committed suicide.

Sequeira A, Morgan L, Walsh DM, Cartagena PM, Choudary P, Li J, Schatzberg AF, Watson SJ, Akil H, Myers RM, Jones EG, Bunney WE, Vawter MP.

PLoS One. 2012;7(4):e35367. doi: 10.1371/journal.pone.0035367. Epub 2012 Apr 30.


Right hemifield deficits in judging simultaneity: a perceptual learning study.

Matthews N, Vawter M, Kelly JG.

J Vis. 2012 Feb 1;12(2). pii: 1. doi: 10.1167/12.2.1.


An integrative functional genomics approach for discovering biomarkers in schizophrenia.

Vawter MP, Mamdani F, Macciardi F.

Brief Funct Genomics. 2011 Nov;10(6):387-99. doi: 10.1093/bfgp/elr036. Epub 2011 Dec 8. Review.


Ketamine influences CLOCK:BMAL1 function leading to altered circadian gene expression.

Bellet MM, Vawter MP, Bunney BG, Bunney WE, Sassone-Corsi P.

PLoS One. 2011;6(8):e23982. doi: 10.1371/journal.pone.0023982. Epub 2011 Aug 24.


Lack of association to a NRG1 missense polymorphism in schizophrenia or bipolar disorder in a Costa Rican population.

Moon E, Rollins B, Mesén A, Sequeira A, Myers RM, Akil H, Watson SJ, Barchas J, Jones EG, Schatzberg A, Bunney WE, DeLisi LE, Byerley W, Vawter MP.

Schizophr Res. 2011 Sep;131(1-3):52-7. doi: 10.1016/j.schres.2011.06.024. Epub 2011 Jul 13.


Loss of nuclear factor E2-related factor 1 in the brain leads to dysregulation of proteasome gene expression and neurodegeneration.

Lee CS, Lee C, Hu T, Nguyen JM, Zhang J, Martin MV, Vawter MP, Huang EJ, Chan JY.

Proc Natl Acad Sci U S A. 2011 May 17;108(20):8408-13. doi: 10.1073/pnas.1019209108. Epub 2011 May 2.


The first decade and beyond of transcriptional profiling in schizophrenia.

Sequeira PA, Martin MV, Vawter MP.

Neurobiol Dis. 2012 Jan;45(1):23-36. doi: 10.1016/j.nbd.2011.03.001. Epub 2011 Mar 8. Review.


Identifying gene regulatory networks in schizophrenia.

Potkin SG, Macciardi F, Guffanti G, Fallon JH, Wang Q, Turner JA, Lakatos A, Miles MF, Lander A, Vawter MP, Xie X.

Neuroimage. 2010 Nov 15;53(3):839-47. doi: 10.1016/j.neuroimage.2010.06.036. Epub 2010 Jun 22. Review.


CRY2 is associated with depression.

Lavebratt C, Sjöholm LK, Soronen P, Paunio T, Vawter MP, Bunney WE, Adolfsson R, Forsell Y, Wu JC, Kelsoe JR, Partonen T, Schalling M.

PLoS One. 2010 Feb 24;5(2):e9407. doi: 10.1371/journal.pone.0009407.

Supplemental Content

Loading ...
Support Center