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Items: 1 to 50 of 360

1.

Impact of Temporal Heterogeneity of Acute Hypoxia on the Radiation Response of Experimental Tumors.

Xu L, Vaupel P, Menze BH, Shi K.

Adv Exp Med Biol. 2018;1072:189-194. doi: 10.1007/978-3-319-91287-5_30.

PMID:
30178344
2.

Hypoxia-/HIF-1α-Driven Factors of the Tumor Microenvironment Impeding Antitumor Immune Responses and Promoting Malignant Progression.

Vaupel P, Multhoff G.

Adv Exp Med Biol. 2018;1072:171-175. doi: 10.1007/978-3-319-91287-5_27.

PMID:
30178341
3.

Biophysical and photobiological basics of water-filtered infrared-A hyperthermia of superficial tumors.

Vaupel P, Piazena H, Müller W, Notter M.

Int J Hyperthermia. 2018;35(1):26-36. doi: 10.1080/02656736.2018.1469169. Epub 2018 May 10.

PMID:
29745269
4.
5.

Master of Science (MSc) Program in Radiation Biology: An Interdepartmental Course Bridging the Gap between Radiation-Related Preclinical and Clinical Disciplines to Prepare Next-Generation Medical Scientists.

Combs SE, Kessel C, Wilkens JJ, Multhoff G, Schmid TE, Vaupel P, Trott KR, Berberat P, Atkinson MJ.

Front Oncol. 2017 Sep 22;7:226. doi: 10.3389/fonc.2017.00226. eCollection 2017.

6.

Inclusion of PET-CT into planning of primary or neoadjuvant chemoradiotherapy of esophageal cancer improves prognosis.

Metzger JC, Wollschläger D, Miederer M, Vaupel P, Moehler M, Schmidberger H, Mayer A.

Strahlenther Onkol. 2017 Oct;193(10):791-799. doi: 10.1007/s00066-017-1164-3. Epub 2017 Aug 2.

PMID:
28770295
7.

Integrating Hyperthermia into Modern Radiation Oncology: What Evidence Is Necessary?

Peeken JC, Vaupel P, Combs SE.

Front Oncol. 2017 Jun 30;7:132. doi: 10.3389/fonc.2017.00132. eCollection 2017. Review.

8.

ESPEN expert group recommendations for action against cancer-related malnutrition.

Arends J, Baracos V, Bertz H, Bozzetti F, Calder PC, Deutz NEP, Erickson N, Laviano A, Lisanti MP, Lobo DN, McMillan DC, Muscaritoli M, Ockenga J, Pirlich M, Strasser F, de van der Schueren M, Van Gossum A, Vaupel P, Weimann A.

Clin Nutr. 2017 Oct;36(5):1187-1196. doi: 10.1016/j.clnu.2017.06.017. Epub 2017 Jun 23. Review.

PMID:
28689670
9.

Computational Simulation of Tumor Hypoxia Based on In Vivo Microvasculature Assessed in a Dorsal Skin Window Chamber.

Xu L, Vaupel P, Bai S, Menze B, Shi K.

Adv Exp Med Biol. 2017;977:109-117. doi: 10.1007/978-3-319-55231-6_15.

PMID:
28685434
10.

Multiparametric Analysis of the Tumor Microenvironment: Hypoxia Markers and Beyond.

Mayer A, Vaupel P.

Adv Exp Med Biol. 2017;977:101-107. doi: 10.1007/978-3-319-55231-6_14. Review.

PMID:
28685433
11.

Tumor Oxygenation Status: Facts and Fallacies.

Vaupel P, Mayer A.

Adv Exp Med Biol. 2017;977:91-99. doi: 10.1007/978-3-319-55231-6_13. Review.

PMID:
28685432
12.

Induction of dormancy in hypoxic human papillomavirus-positive cancer cells.

Hoppe-Seyler K, Bossler F, Lohrey C, Bulkescher J, Rösl F, Jansen L, Mayer A, Vaupel P, Dürst M, Hoppe-Seyler F.

Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E990-E998. doi: 10.1073/pnas.1615758114. Epub 2017 Jan 23.

13.

Matching the reaction-diffusion simulation to dynamic [18F]FMISO PET measurements in tumors: extension to a flow-limited oxygen-dependent model.

Shi K, Bayer C, Gaertner FC, Astner ST, Wilkens JJ, Nüsslin F, Vaupel P, Ziegler SI.

Physiol Meas. 2017 Feb;38(2):188-204. doi: 10.1088/1361-6579/aa5071. Epub 2017 Jan 5.

PMID:
28055983
14.

Downregulation of EGFR in hypoxic, diffusion-limited areas of squamous cell carcinomas of the head and neck.

Mayer A, Zahnreich S, Brieger J, Vaupel P, Schmidberger H.

Br J Cancer. 2016 Nov 22;115(11):1351-1358. doi: 10.1038/bjc.2016.336. Epub 2016 Nov 1.

15.

Commentary: A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment.

Vaupel P, Multhoff G.

Front Immunol. 2016 Aug 31;7:332. doi: 10.3389/fimmu.2016.00332. eCollection 2016. No abstract available.

17.

Molecular Imaging of Tumor Hypoxia: Existing Problems and Their Potential Model-Based Solutions.

Shi K, Ziegler SI, Vaupel P.

Adv Exp Med Biol. 2016;923:87-93. doi: 10.1007/978-3-319-38810-6_12.

PMID:
27526129
18.

Tumor Hypoxia: Causative Mechanisms, Microregional Heterogeneities, and the Role of Tissue-Based Hypoxia Markers.

Vaupel P, Mayer A.

Adv Exp Med Biol. 2016;923:77-86. doi: 10.1007/978-3-319-38810-6_11. Review.

PMID:
27526128
19.

Quantitative Analysis of [18F]FMISO PET for Tumor Hypoxia: Correlation of Modeling Results with Immunohistochemistry.

Shi K, Bayer C, Astner ST, Gaertner FC, Vaupel P, Schwaiger M, Huang SC, Ziegler SI.

Mol Imaging Biol. 2017 Feb;19(1):120-129. doi: 10.1007/s11307-016-0975-4.

PMID:
27379986
20.

Pathophysiological Basis for the Formation of the Tumor Microenvironment.

Horsman MR, Vaupel P.

Front Oncol. 2016 Apr 12;6:66. doi: 10.3389/fonc.2016.00066. eCollection 2016. Review.

21.

Adenosine can thwart antitumor immune responses elicited by radiotherapy : Therapeutic strategies alleviating protumor ADO activities.

Vaupel P, Multhoff G.

Strahlenther Onkol. 2016 May;192(5):279-87. doi: 10.1007/s00066-016-0948-1. Epub 2016 Mar 9. Review.

PMID:
26961686
22.

Hypoxia-Associated Marker CA IX Does Not Predict the Response of Locally Advanced Rectal Cancers to Neoadjuvant Chemoradiotherapy.

Mayer A, Vaupel P, Oberholzer K, Ebert M, Dimitrow M, Kreft A, Mueller-Klieser W, Schmidberger H.

Adv Exp Med Biol. 2016;876:195-200. doi: 10.1007/978-1-4939-3023-4_24.

PMID:
26782212
23.

Hypoxia-Driven Adenosine Accumulation: A Crucial Microenvironmental Factor Promoting Tumor Progression.

Vaupel P, Mayer A.

Adv Exp Med Biol. 2016;876:177-183. doi: 10.1007/978-1-4939-3023-4_22.

PMID:
26782210
24.

Stress Response Leading to Resistance in Glioblastoma-The Need for Innovative Radiotherapy (iRT) Concepts.

Combs SE, Schmid TE, Vaupel P, Multhoff G.

Cancers (Basel). 2016 Jan 13;8(1). pii: E15. doi: 10.3390/cancers8010015. Review.

25.

Can respiratory hyperoxia mitigate adenosine-driven suppression of antitumor immunity?

Vaupel P, Mayer A.

Ann Transl Med. 2015 Nov;3(19):292. doi: 10.3978/j.issn.2305-5839.2015.09.23. No abstract available.

26.

Temporal changes in tumor oxygenation and perfusion upon normo- and hyperbaric inspiratory hyperoxia.

Thews O, Vaupel P.

Strahlenther Onkol. 2016 Mar;192(3):174-81. doi: 10.1007/s00066-015-0916-1. Epub 2015 Oct 26.

PMID:
26501141
27.

Spatial oxygenation profiles in tumors during normo- and hyperbaric hyperoxia.

Thews O, Vaupel P.

Strahlenther Onkol. 2015 Nov;191(11):875-82. doi: 10.1007/s00066-015-0867-6. Epub 2015 Jul 2.

PMID:
26135917
28.

Adjuvant temozolomide-based chemoradiotherapy versus radiotherapy alone in patients with WHO III astrocytoma: The Mainz experience.

Mayer A, Schwanbeck C, Sommer C, Stockinger M, Giese A, Renovanz M, Vaupel P, Schmidberger H.

Strahlenther Onkol. 2015 Aug;191(8):665-71. doi: 10.1007/s00066-015-0855-x. Epub 2015 May 30.

PMID:
26025143
29.

Exploring the quantitative relationship between metabolism and enzymatic phenotype by physiological modeling of glucose metabolism and lactate oxidation in solid tumors.

Wang Q, Vaupel P, Ziegler SI, Shi K.

Phys Med Biol. 2015 Mar 21;60(6):2547-71. doi: 10.1088/0031-9155/60/6/2547. Epub 2015 Mar 12.

PMID:
25761504
30.

Response to commentary by Champ and Klement: Is a ketogenic diet the solution for the hyperglycemia problem in glioblastoma therapy?

Mayer A, Vaupel P, Struss HG, Giese A, Stockinger M, Schmidberger H.

Strahlenther Onkol. 2015 Mar;191(3):283-4. doi: 10.1007/s00066-014-0793-z. No abstract available.

PMID:
25595495
31.

The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities.

Vaupel P, Mayer A.

Antioxid Redox Signal. 2015 Apr 1;22(10):878-80. doi: 10.1089/ars.2014.6155. Epub 2014 Dec 10. No abstract available.

PMID:
25340660
32.

GLUT-1 expression is largely unrelated to both hypoxia and the Warburg phenotype in squamous cell carcinomas of the vulva.

Mayer A, Schmidt M, Seeger A, Serras AF, Vaupel P, Schmidberger H.

BMC Cancer. 2014 Oct 12;14:760. doi: 10.1186/1471-2407-14-760.

33.

Strong adverse prognostic impact of hyperglycemic episodes during adjuvant chemoradiotherapy of glioblastoma multiforme.

Mayer A, Vaupel P, Struss HG, Giese A, Stockinger M, Schmidberger H.

Strahlenther Onkol. 2014 Oct;190(10):933-8. doi: 10.1007/s00066-014-0696-z. Epub 2014 Jun 18.

PMID:
24938515
34.

Heterogeneity in tissue oxygenation: from physiological variability in normal tissues to pathophysiological chaos in malignant tumours.

Harrison DK, Vaupel P.

Adv Exp Med Biol. 2014;812:25-31. doi: 10.1007/978-1-4939-0620-8_4.

PMID:
24729211
35.

Hypoxia in tumors: pathogenesis-related classification, characterization of hypoxia subtypes, and associated biological and clinical implications.

Vaupel P, Mayer A.

Adv Exp Med Biol. 2014;812:19-24. doi: 10.1007/978-1-4939-0620-8_3. Review.

PMID:
24729210
36.

Critical role of aberrant angiogenesis in the development of tumor hypoxia and associated radioresistance.

Multhoff G, Radons J, Vaupel P.

Cancers (Basel). 2014 Apr 8;6(2):813-28. doi: 10.3390/cancers6020813.

37.

Preclinical evaluation of parametric image reconstruction of [18F]FMISO PET: correlation with ex vivo immunohistochemistry.

Cheng X, Bayer C, Maftei CA, Astner ST, Vaupel P, Ziegler SI, Shi K.

Phys Med Biol. 2014 Jan 20;59(2):347-62. doi: 10.1088/0031-9155/59/2/347. Epub 2013 Dec 19.

PMID:
24351879
38.

Tumor oxygenation: an appraisal of past and present concepts and a look into the future : Arisztid G. B. Kovách Lecture.

Vaupel P.

Adv Exp Med Biol. 2013;789:229-236. doi: 10.1007/978-1-4614-7411-1_31.

PMID:
23852499
39.

Hypoxia, lactate accumulation, and acidosis: siblings or accomplices driving tumor progression and resistance to therapy?

Mayer A, Vaupel P.

Adv Exp Med Biol. 2013;789:203-209. doi: 10.1007/978-1-4614-7411-1_28. Review.

PMID:
23852496
40.

Lacking hypoxia-mediated downregulation of E-cadherin in cancers of the uterine cervix.

Mayer A, Höckel M, Schlischewsky N, Schmidberger H, Horn LC, Vaupel P.

Br J Cancer. 2013 Feb 5;108(2):402-8. doi: 10.1038/bjc.2012.570. Epub 2013 Jan 15.

41.
42.

[Tumor pathophysiology].

Kunz-Schughart LA, Mueller-Klieser W, Vaupel P.

Strahlenther Onkol. 2012 Nov;188 Suppl 3:299-303. doi: 10.1007/s00066-012-0203-3. Review. German. No abstract available.

PMID:
23053151
43.

Blood flow and oxygenation status of prostate cancers.

Vaupel P, Kelleher DK.

Adv Exp Med Biol. 2013;765:299-305. doi: 10.1007/978-1-4614-4989-8_42.

PMID:
22879048
44.

Blood flow and associated pathophysiology of uterine cervix cancers: characterisation and relevance for localised hyperthermia.

Vaupel PW, Kelleher DK.

Int J Hyperthermia. 2012;28(6):518-27. doi: 10.3109/02656736.2012.699134. Epub 2012 Jul 27. Review.

PMID:
22838732
45.

Differential expression of HIF-1 in glioblastoma multiforme and anaplastic astrocytoma.

Mayer A, Schneider F, Vaupel P, Sommer C, Schmidberger H.

Int J Oncol. 2012 Oct;41(4):1260-70. doi: 10.3892/ijo.2012.1555. Epub 2012 Jul 16.

46.

Intra- and intertumor heterogeneities in total, chronic, and acute hypoxia in xenografted squamous cell carcinomas. Detection and quantification using (immuno-)fluorescence techniques.

Maftei CA, Bayer C, Shi K, Vaupel P.

Strahlenther Onkol. 2012 Jul;188(7):606-15. doi: 10.1007/s00066-012-0105-4. Epub 2012 Jun 14.

PMID:
22695745
47.

Availability, not respiratory capacity governs oxygen consumption of solid tumors.

Vaupel P, Mayer A.

Int J Biochem Cell Biol. 2012 Sep;44(9):1477-81. doi: 10.1016/j.biocel.2012.05.019. Epub 2012 Jun 1. Review.

PMID:
22664330
48.

Acute versus chronic hypoxia in tumors: Controversial data concerning time frames and biological consequences.

Bayer C, Vaupel P.

Strahlenther Onkol. 2012 Jul;188(7):616-27. doi: 10.1007/s00066-012-0085-4. Epub 2012 Mar 29. Review.

PMID:
22454045
49.

Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1α.

Schilling D, Bayer C, Li W, Molls M, Vaupel P, Multhoff G.

PLoS One. 2012;7(2):e31110. doi: 10.1371/journal.pone.0031110. Epub 2012 Feb 7.

50.

Basal HIF-1α expression levels are not predictive for radiosensitivity of human cancer cell lines.

Schilling D, Bayer C, Emmerich K, Molls M, Vaupel P, Huber RM, Multhoff G.

Strahlenther Onkol. 2012 Apr;188(4):353-8. doi: 10.1007/s00066-011-0051-6. Epub 2012 Feb 10.

PMID:
22318330

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