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Items: 1 to 50 of 538

1.

Interactions between the gravitostat and the fibroblast growth factor system for the regulation of body weight.

Palsdottir V, Windahl SH, Hägg DA, Keantar H, Bellman J, Buchanan A, Vaughan TJ, Lindén D, Jansson JO, Ohlsson C.

Endocrinology. 2019 Mar 19. pii: en.2018-01002. doi: 10.1210/en.2018-01002. [Epub ahead of print]

PMID:
30888399
2.

Correction to: NSAID use and somatic exomic mutations in Barrett's esophagus.

Galipeau PC, Oman KM, Paulson TG, Sanchez CA, Zhang Q, Marty JA, Delrow JJ, Kuhner MK, Vaughan TL, Reid BJ, Li X.

Genome Med. 2019 Mar 12;11(1):14. doi: 10.1186/s13073-019-0625-y.

3.

Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1.

Vousden KA, Lundqvist T, Popovic B, Naiman B, Carruthers AM, Newton P, Johnson DJD, Pomowski A, Wilkinson T, Dufner P, de Mendez I, Mallinder PR, Murray C, Strain M, Connor J, Murray LA, Sleeman MA, Lowe DC, Huntington JA, Vaughan TJ.

Sci Rep. 2019 Feb 7;9(1):1605. doi: 10.1038/s41598-019-38842-x.

4.

No Association Between Vitamin D Status and Risk of Barrett's Esophagus or Esophageal Adenocarcinoma-a Mendelian Randomization Study.

Dong J, Gharahkhani P, Chow WH, Gammon MD, Liu G, Caldas C, Wu AH, Ye W, Onstad L, Anderson LA, Bernstein L, Pharoah PD, Risch HA, Corley DA, Fitzgerald RC; Stomach and Esophageal Cancer Study (SOCS) Consortium, Iyer PG, Reid BJ, Lagergren J, Shaheen NJ, Vaughan TL, MacGregor S, Love S, Palles C, Tomlinson I, Gockel I, May A, Gerges C, Anders M, Böhmer AC, Becker J, Kreuser N, Thieme R, Noder T, Venerito M, Veits L, Schmidt T, Schmidt C, Izbicki JR, Hölscher AH, Lang H, Lorenz D, Schumacher B, Mayershofer R, Vashist Y, Ott K, Vieth M, Weismüller J, Nöthen MM, Moebus S, Knapp M, Peters WHM, Neuhaus H, Rösch T, Ell C, Jankowski J, Schumacher J, Neale RE, Whiteman DC, Thrift AP.

Clin Gastroenterol Hepatol. 2019 Feb 1. pii: S1542-3565(19)30088-6. doi: 10.1016/j.cgh.2019.01.041. [Epub ahead of print]

PMID:
30716477
5.

Lunasin does not slow ALS progression: results of an open-label, single-center, hybrid-virtual 12-month trial.

Bedlack RS, Wicks P, Vaughan T, Opie A, Blum R, Dios A, Sadri-Vakili G.

Amyotroph Lateral Scler Frontotemporal Degener. 2019 Jan 21:1-9. doi: 10.1080/21678421.2018.1556698. [Epub ahead of print]

PMID:
30663902
6.

Predictors of Nasoseptal Flap Use After Endoscopic Transsphenoidal Pituitary Mass Resection.

Rotman LE, Kicielinski KP, Broadwater DR, Davis MC, Vaughan TB, Woodworth BA, Riley KO.

World Neurosurg. 2018 Dec 30. pii: S1878-8750(18)32920-6. doi: 10.1016/j.wneu.2018.12.097. [Epub ahead of print]

PMID:
30599246
7.

Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes treatment.

Chodorge M, Celeste AJ, Grimsby J, Konkar A, Davidsson P, Fairman D, Jenkinson L, Naylor J, White N, Seaman JC, Dickson K, Kemp B, Spooner J, Rossy E, Hornigold DC, Trevaskis JL, Bond NJ, London TB, Buchanan A, Vaughan T, Rondinone CM, Osbourn JK.

Sci Rep. 2018 Dec 3;8(1):17545. doi: 10.1038/s41598-018-35869-4.

8.

Computational Design of Epitope-Specific Functional Antibodies.

Nimrod G, Fischman S, Austin M, Herman A, Keyes F, Leiderman O, Hargreaves D, Strajbl M, Breed J, Klompus S, Minton K, Spooner J, Buchanan A, Vaughan TJ, Ofran Y.

Cell Rep. 2018 Nov 20;25(8):2121-2131.e5. doi: 10.1016/j.celrep.2018.10.081.

9.

Long-Term Survival After Transformation of an Adrenocorticotropic Hormone-Secreting Pituitary Macroadenoma to a Silent Corticotroph Pituitary Carcinoma.

Rotman LE, Vaughan TB, Hackney JR, Riley KO.

World Neurosurg. 2019 Feb;122:417-423. doi: 10.1016/j.wneu.2018.11.011. Epub 2018 Nov 14.

PMID:
30447452
10.

Whole-genome sequencing of esophageal adenocarcinoma in Chinese patients reveals distinct mutational signatures and genomic alterations.

Dai JY, Wang X, Buas MF, Zhang C, Ma J, Wei B, Li Y, Zhao B, Hyun TS, Chen X, Loeb KR, Odze R, Yao L, Sun X, Self S, Vaughan TL, Guo Y.

Commun Biol. 2018 Oct 24;1:174. doi: 10.1038/s42003-018-0182-8. eCollection 2018.

11.

Haplosaurus computes protein haplotypes for use in precision drug design.

Spooner W, McLaren W, Slidel T, Finch DK, Butler R, Campbell J, Eghobamien L, Rider D, Kiefer CM, Robinson MJ, Hardman C, Cunningham F, Vaughan T, Flicek P, Huntington CC.

Nat Commun. 2018 Oct 8;9(1):4128. doi: 10.1038/s41467-018-06542-1.

12.

Letter to the Editor. Atypical pituitary adenoma.

Rotman LE, Vaughan TB, Hackney JR, Riley KO.

J Neurosurg. 2018 Dec 1;129(6):1657-1659. doi: 10.3171/2018.7.JNS181961. No abstract available.

PMID:
30215564
13.

Detection of HIV transmission clusters from phylogenetic trees using a multi-state birth-death model.

Barido-Sottani J, Vaughan TG, Stadler T.

J R Soc Interface. 2018 Sep;15(146). pii: 20180512. doi: 10.1098/rsif.2018.0512.

14.

High affinity single-chain variable fragments are specific and versatile targeting motifs for extracellular vesicles.

Longatti A, Schindler C, Collinson A, Jenkinson L, Matthews C, Fitzpatrick L, Blundy M, Minter R, Vaughan T, Shaw M, Tigue N.

Nanoscale. 2018 Aug 7;10(29):14230-14244. doi: 10.1039/c8nr03970d. Epub 2018 Jul 16.

PMID:
30010165
15.

Independent home use of a brain-computer interface by people with amyotrophic lateral sclerosis.

Wolpaw JR, Bedlack RS, Reda DJ, Ringer RJ, Banks PG, Vaughan TM, Heckman SM, McCane LM, Carmack CS, Winden S, McFarland DJ, Sellers EW, Shi H, Paine T, Higgins DS, Lo AC, Patwa HS, Hill KJ, Huang GD, Ruff RL.

Neurology. 2018 Jul 17;91(3):e258-e267. doi: 10.1212/WNL.0000000000005812. Epub 2018 Jun 27.

PMID:
29950436
16.

Helicobacter pylori Infection Is Associated With Reduced Risk of Barrett's Esophagus: An Analysis of the Barrett's and Esophageal Adenocarcinoma Consortium.

Wang Z, Shaheen NJ, Whiteman DC, Anderson LA, Vaughan TL, Corley DA, El-Serag HB, Rubenstein JH, Thrift AP.

Am J Gastroenterol. 2018 Aug;113(8):1148-1155. doi: 10.1038/s41395-018-0070-3. Epub 2018 Jun 8.

PMID:
29880962
17.

Racial differences in the relationship between tobacco, alcohol, and the risk of head and neck cancer: pooled analysis of US studies in the INHANCE Consortium.

Voltzke KJ, Lee YA, Zhang ZF, Zevallos JP, Yu GP, Winn DM, Vaughan TL, Sturgis EM, Smith E, Schwartz SM, Schantz S, Muscat J, Morgenstern H, McClean M, Li G, Lazarus P, Kelsey K, Gillison M, Chen C, Boffetta P, Hashibe M, Olshan AF.

Cancer Causes Control. 2018 Jul;29(7):619-630. doi: 10.1007/s10552-018-1026-z. Epub 2018 May 14.

PMID:
29761303
18.

Lorenz Curves and Gini Coefficient Analyses Indicate Inefficiencies in Esophageal Adenocarcinoma Screening.

Hur C, Zhan T, Thrift AP, Vaughan TL, Feuer EJ.

Clin Gastroenterol Hepatol. 2019 Feb;17(3):560-562.e2. doi: 10.1016/j.cgh.2018.05.002. Epub 2018 May 9.

PMID:
29753084
19.

Investigating the interplay between substrate stiffness and ligand chemistry in directing mesenchymal stem cell differentiation within 3D macro-porous substrates.

Haugh MG, Vaughan TJ, Madl CM, Raftery RM, McNamara LM, O'Brien FJ, Heilshorn SC.

Biomaterials. 2018 Jul;171:23-33. doi: 10.1016/j.biomaterials.2018.04.026. Epub 2018 Apr 16.

PMID:
29677521
20.

Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus.

Dong J, Levine DM, Buas MF, Zhang R, Onstad L, Fitzgerald RC; Stomach and Oesophageal Cancer Study (SOCS) Consortium, Corley DA, Shaheen NJ, Lagergren J, Hardie LJ, Reid BJ, Iyer PG, Risch HA, Caldas C, Caldas I, Pharoah PD, Liu G, Gammon MD, Chow WH, Bernstein L, Bird NC, Ye W, Wu AH, Anderson LA, MacGregor S, Whiteman DC, Vaughan TL, Thrift AP.

Clin Gastroenterol Hepatol. 2018 Oct;16(10):1598-1606.e4. doi: 10.1016/j.cgh.2018.03.007. Epub 2018 Mar 15.

21.

NSAID use and somatic exomic mutations in Barrett's esophagus.

Galipeau PC, Oman KM, Paulson TG, Sanchez CA, Zhang Q, Marty JA, Delrow JJ, Kuhner MK, Vaughan TL, Reid BJ, Li X.

Genome Med. 2018 Feb 27;10(1):17. doi: 10.1186/s13073-018-0520-y. Erratum in: Genome Med. 2019 Mar 12;11(1):14.

22.

Determining Risk of Barrett's Esophagus and Esophageal Adenocarcinoma Based on Epidemiologic Factors and Genetic Variants.

Dong J, Buas MF, Gharahkhani P, Kendall BJ, Onstad L, Zhao S, Anderson LA, Wu AH, Ye W, Bird NC, Bernstein L, Chow WH, Gammon MD, Liu G, Caldas C, Pharoah PD, Risch HA, Iyer PG, Reid BJ, Hardie LJ, Lagergren J, Shaheen NJ, Corley DA, Fitzgerald RC; Stomach and Oesophageal Cancer Study (SOCS) consortium, Whiteman DC, Vaughan TL, Thrift AP.

Gastroenterology. 2018 Apr;154(5):1273-1281.e3. doi: 10.1053/j.gastro.2017.12.003. Epub 2017 Dec 13.

23.

Development of a population-based cancer case-control study in southern china.

Ye W, Chang ET, Liu Z, Liu Q, Cai Y, Zhang Z, Chen G, Huang QH, Xie SH, Cao SM, Shao JY, Jia WH, Zheng Y, Liao J, Chen Y, Lin L, Liang L, Ernberg I, Vaughan TL, Huang G, Zeng Y, Zeng YX, Adami HO.

Oncotarget. 2017 Jul 29;8(50):87073-87085. doi: 10.18632/oncotarget.19692. eCollection 2017 Oct 20.

24.

A pooled analysis of dietary sugar/carbohydrate intake and esophageal and gastric cardia adenocarcinoma incidence and survival in the USA.

Li N, Petrick JL, Steck SE, Bradshaw PT, McClain KM, Niehoff NM, Engel LS, Shaheen NJ, Risch HA, Vaughan TL, Wu AH, Gammon MD.

Int J Epidemiol. 2017 Dec 1;46(6):1836-1846. doi: 10.1093/ije/dyx203.

25.

Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors.

Colley CS, Popovic B, Sridharan S, Debreczeni JE, Hargeaves D, Fung M, An LL, Edwards B, Arnold J, England E, Eghobamien L, Sivars U, Flavell L, Renshaw J, Wickson K, Warrener P, Zha J, Bonnell J, Woods R, Wilkinson T, Dobson C, Vaughan TJ.

MAbs. 2018 Jan;10(1):104-117. doi: 10.1080/19420862.2017.1384892. Epub 2017 Oct 24.

26.

Dietary sugar/starches intake and Barrett's esophagus: a pooled analysis.

Li N, Petrick JL, Steck SE, Bradshaw PT, McClain KM, Niehoff NM, Engel LS, Shaheen NJ, Corley DA, Vaughan TL, Gammon MD.

Eur J Epidemiol. 2017 Nov;32(11):1007-1017. doi: 10.1007/s10654-017-0301-8. Epub 2017 Sep 1.

27.

Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.

Douthwaite J, Moisan J, Privezentzev C, Soskic B, Sabbah S, Cohen S, Collinson A, England E, Huntington C, Kemp B, Zhuang L, Hudak S, Rees DG, Goldberg D, Barton C, Chang L, Vainshtein I, Liang M, Iciek L, Ambery P, Peakman M, Vaughan TJ, Tree TIM, Sansom DM, Bowen MA, Minter RR, Jermutus L.

J Immunol. 2017 Sep 1;199(5):1943. doi: 10.4049/jimmunol.1790013. No abstract available.

28.

A coupled diffusion-fluid pressure model to predict cell density distribution for cells encapsulated in a porous hydrogel scaffold under mechanical loading.

Zhao F, Vaughan TJ, Mc Garrigle MJ, McNamara LM.

Comput Biol Med. 2017 Oct 1;89:181-189. doi: 10.1016/j.compbiomed.2017.08.003. Epub 2017 Aug 3.

PMID:
28822899
29.

In silico study of bone tissue regeneration in an idealised porous hydrogel scaffold using a mechano-regulation algorithm.

Zhao F, Mc Garrigle MJ, Vaughan TJ, McNamara LM.

Biomech Model Mechanobiol. 2018 Feb;17(1):5-18. doi: 10.1007/s10237-017-0941-3. Epub 2017 Aug 4.

PMID:
28779266
30.

The Evolving Genomic Landscape of Barrett's Esophagus and Esophageal Adenocarcinoma.

Contino G, Vaughan TL, Whiteman D, Fitzgerald RC.

Gastroenterology. 2017 Sep;153(3):657-673.e1. doi: 10.1053/j.gastro.2017.07.007. Epub 2017 Jul 14. Review.

31.

Taming the BEAST-A Community Teaching Material Resource for BEAST 2.

Barido-Sottani J, Bošková V, Plessis LD, Kühnert D, Magnus C, Mitov V, Müller NF, PecErska J, Rasmussen DA, Zhang C, Drummond AJ, Heath TA, Pybus OG, Vaughan TG, Stadler T.

Syst Biol. 2018 Jan 1;67(1):170-174. doi: 10.1093/sysbio/syx060.

32.

Active and Passive Smoking and Risk of Nasopharyngeal Carcinoma: A Population-Based Case-Control Study in Southern China.

Chang ET, Liu Z, Hildesheim A, Liu Q, Cai Y, Zhang Z, Chen G, Xie SH, Cao SM, Shao JY, Jia WH, Zheng Y, Liao J, Chen Y, Lin L, Ernberg I, Vaughan TL, Adami HO, Huang G, Zeng Y, Zeng YX, Ye W.

Am J Epidemiol. 2017 Jun 15;185(12):1272-1280. doi: 10.1093/aje/kwx018.

33.

The effect of equiaxial stretching on the osteogenic differentiation and mechanical properties of human adipose stem cells.

Virjula S, Zhao F, Leivo J, Vanhatupa S, Kreutzer J, Vaughan TJ, Honkala AM, Viehrig M, Mullen CA, Kallio P, McNamara LM, Miettinen S.

J Mech Behav Biomed Mater. 2017 Aug;72:38-48. doi: 10.1016/j.jmbbm.2017.04.016. Epub 2017 Apr 13.

PMID:
28448920
34.

IcyTree: rapid browser-based visualization for phylogenetic trees and networks.

Vaughan TG.

Bioinformatics. 2017 Aug 1;33(15):2392-2394. doi: 10.1093/bioinformatics/btx155.

35.

MEDI1873, a potent, stabilized hexameric agonist of human GITR with regulatory T-cell targeting potential.

Tigue NJ, Bamber L, Andrews J, Ireland S, Hair J, Carter E, Sridharan S, Jovanović J, Rees DG, Springall JS, Solier E, Li YM, Chodorge M, Perez-Martinez D, Higazi DR, Oberst M, Kennedy M, Black CM, Yan L, Schwickart M, Maguire S, Cann JA, de Haan L, Young LL, Vaughan T, Wilkinson RW, Stewart R.

Oncoimmunology. 2017 Feb 3;6(3):e1280645. doi: 10.1080/2162402X.2017.1280645. eCollection 2017.

36.

External Validation of the Michigan Barrett's Esophagus Prediction Tool.

Thrift AP, Vaughan TL, Anderson LA, Whiteman DC, El-Serag HB.

Clin Gastroenterol Hepatol. 2017 Jul;15(7):1124-1126. doi: 10.1016/j.cgh.2017.03.004. Epub 2017 Mar 11. No abstract available.

37.

Quantification of familial risk of nasopharyngeal carcinoma in a high-incidence area.

Liu Z, Chang ET, Liu Q, Cai Y, Zhang Z, Chen G, Huang QH, Xie SH, Cao SM, Shao JY, Jia WH, Zheng Y, Liao J, Chen Y, Lin L, Liang L, Ernberg I, Vaughan TL, Adami HO, Huang G, Zeng Y, Zeng YX, Ye W.

Cancer. 2017 Jul 15;123(14):2716-2725. doi: 10.1002/cncr.30643. Epub 2017 Feb 27.

38.

Rate of Asparagine Deamidation in a Monoclonal Antibody Correlating with Hydrogen Exchange Rate at Adjacent Downstream Residues.

Phillips JJ, Buchanan A, Andrews J, Chodorge M, Sridharan S, Mitchell L, Burmeister N, Kippen AD, Vaughan TJ, Higazi DR, Lowe D.

Anal Chem. 2017 Feb 21;89(4):2361-2368. doi: 10.1021/acs.analchem.6b04158. Epub 2017 Feb 3.

PMID:
28194941
39.

Candidate serum metabolite biomarkers for differentiating gastroesophageal reflux disease, Barrett's esophagus, and high-grade dysplasia/esophageal adenocarcinoma.

Buas MF, Gu H, Djukovic D, Zhu J, Onstad L, Reid BJ, Raftery D, Vaughan TL.

Metabolomics. 2017 Mar;13(3). pii: 23. doi: 10.1007/s11306-016-1154-y. Epub 2017 Jan 20.

40.

Engineering the expression of an anti-interleukin-13 antibody through rational design and mutagenesis.

Popovic B, Gibson S, Senussi T, Carmen S, Kidd S, Slidel T, Strickland I, Jianqing X, Spooner J, Lewis A, Hudson N, Mackenzie L, Keen J, Kemp B, Hardman C, Hatton D, Wilkinson T, Vaughan T, Lowe D.

Protein Eng Des Sel. 2017 Apr 1;30(4):303-311. doi: 10.1093/protein/gzx001.

PMID:
28130326
41.

Evidence against a role for jaagsiekte sheep retrovirus in human lung cancer.

Miller AD, De Las Heras M, Yu J, Zhang F, Liu SL, Vaughan AE, Vaughan TL, Rosadio R, Rocca S, Palmieri G, Goedert JJ, Fujimoto J, Wistuba II.

Retrovirology. 2017 Jan 20;14(1):3. doi: 10.1186/s12977-017-0329-6.

42.

Juror Decision-making in Death Penalty Sentencing when Presented with Defendant's History of Child Abuse or Neglect.

Bell Holleran LL, Vaughan TJ, Vandiver DM.

Behav Sci Law. 2016 Nov;34(6):742-766. doi: 10.1002/bsl.2271. Epub 2017 Jan 18.

PMID:
28098410
43.

Inferring Ancestral Recombination Graphs from Bacterial Genomic Data.

Vaughan TG, Welch D, Drummond AJ, Biggs PJ, George T, French NP.

Genetics. 2017 Feb;205(2):857-870. doi: 10.1534/genetics.116.193425. Epub 2016 Dec 22.

44.

Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo.

Dobson CL, Devine PW, Phillips JJ, Higazi DR, Lloyd C, Popovic B, Arnold J, Buchanan A, Lewis A, Goodman J, van der Walle CF, Thornton P, Vinall L, Lowne D, Aagaard A, Olsson LL, Ridderstad Wollberg A, Welsh F, Karamanos TK, Pashley CL, Iadanza MG, Ranson NA, Ashcroft AE, Kippen AD, Vaughan TJ, Radford SE, Lowe DC.

Sci Rep. 2016 Dec 20;6:38644. doi: 10.1038/srep38644.

45.

Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2.

Popovic B, Breed J, Rees DG, Gardener MJ, Vinall LM, Kemp B, Spooner J, Keen J, Minter R, Uddin F, Colice G, Wilkinson T, Vaughan T, May RD.

J Mol Biol. 2017 Jan 20;429(2):208-219. doi: 10.1016/j.jmb.2016.12.005. Epub 2016 Dec 9.

46.

A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.

Douthwaite J, Moisan J, Privezentzev C, Soskic B, Sabbah S, Cohen S, Collinson A, England E, Huntington C, Kemp B, Zhuang L, Hudak S, Rees DG, Goldberg D, Barton C, Chang L, Vainshtein I, Liang M, Iciek L, Ambery P, Peakman M, Vaughan TJ, Tree TI, Sansom DM, Bowen MA, Minter RR, Jermutus L.

J Immunol. 2017 Jan 1;198(1):528-537. Epub 2016 Nov 23. Erratum in: J Immunol. 2017 Sep 1;199(5):1943.

47.

Altered architecture and cell populations affect bone marrow mechanobiology in the osteoporotic human femur.

Metzger TA, Vaughan TJ, McNamara LM, Niebur GL.

Biomech Model Mechanobiol. 2017 Jun;16(3):841-850. doi: 10.1007/s10237-016-0856-4. Epub 2016 Nov 22.

PMID:
27878399
48.

Nonsteroidal Anti-Inflammatory Drug Use is Not Associated With Reduced Risk of Barrett's Esophagus.

Thrift AP, Anderson LA, Murray LJ, Cook MB, Shaheen NJ, Rubenstein JH, El-Serag HB, Vaughan TL, Schneider JL, Whiteman DC, Corley DA.

Am J Gastroenterol. 2016 Nov;111(11):1528-1535. doi: 10.1038/ajg.2016.348. Epub 2016 Aug 30.

49.

Correction of: Exploring Concordance of Patient-Reported Information on PatientsLikeMe and Medical Claims Data at the Patient Level.

Eichler GS, Cochin E, Han J, Hu S, Vaughan TE, Wicks P, Barr C, Devenport J.

J Med Internet Res. 2016 Oct 27;18(10):e271.

50.

Transition metal complexes of the pyridylphosphine ligand o-C6H4(CH2PPy2)2.

Vaughan TF, Spencer JL.

Dalton Trans. 2016 Nov 14;45(42):16826-16837. Epub 2016 Sep 28.

PMID:
27711717

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