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Is there a significant seasonality in the occurrence of osteoarticular infections?

Uçkay I, Betz M, Vaudaux P, Lauper N, Nicodème JD, Abrassart S, Schindler M, Peter R, Christofilopoulos P.

Infect Dis (Lond). 2015 Apr;47(4):252-4. doi: 10.3109/00365548.2014.979436. Epub 2015 Jan 22.


Increased risk of joint failure in hip prostheses infected with Staphylococcus aureus treated with debridement, antibiotics and implant retention compared to Streptococcus.

Betz M, Abrassart S, Vaudaux P, Gjika E, Schindler M, Billières J, Zenelaj B, Suvà D, Peter R, Uçkay I.

Int Orthop. 2015 Mar;39(3):397-401. doi: 10.1007/s00264-014-2510-z. Epub 2014 Sep 4.


Gram and acridine orange staining for diagnosis of septic arthritis in different patient populations.

Cunningham G, Seghrouchni K, Ruffieux E, Vaudaux P, Gayet-Ageron A, Cherkaoui A, Godinho E, Lew D, Hoffmeyer P, Uçkay I.

Int Orthop. 2014 Jun;38(6):1283-90. doi: 10.1007/s00264-014-2284-3. Epub 2014 Feb 5.


Pathogen-driven decision for implant retention in the management of infected total knee prostheses.

Zürcher-Pfund L, Uçkay I, Legout L, Gamulin A, Vaudaux P, Peter R.

Int Orthop. 2013 Aug;37(8):1471-5. doi: 10.1007/s00264-013-1923-4. Epub 2013 May 22. Review.


The safety and efficacy of high-dose daptomycin combined with rifampicin for the treatment of Gram-positive osteoarticular infections.

Jugun K, Vaudaux P, Garbino J, Pagani L, Hoffmeyer P, Lew D, Uçkay I.

Int Orthop. 2013 Jul;37(7):1375-80. doi: 10.1007/s00264-013-1856-y. Epub 2013 Mar 22.


Prevalence of isolates with reduced glycopeptide susceptibility in orthopedic device-related infections due to methicillin-resistant Staphylococcus aureus.

Vaudaux P, Ferry T, Uçkay I, François P, Schrenzel J, Harbarth S, Renzoni A.

Eur J Clin Microbiol Infect Dis. 2012 Dec;31(12):3367-74. doi: 10.1007/s10096-012-1705-8. Epub 2012 Jul 26.


High prevalence of isolates with reduced glycopeptide susceptibility in persistent or recurrent bloodstream infections due to methicillin-resistant Staphylococcus aureus.

Uçkay I, Bernard L, Buzzi M, Harbarth S, François P, Huggler E, Ferry T, Schrenzel J, Renzoni A, Vaudaux P, Lew DP.

Antimicrob Agents Chemother. 2012 Mar;56(3):1258-64. doi: 10.1128/AAC.05808-11. Epub 2011 Dec 12.


Efficacy of a combined oral clindamycin?rifampicin regimen for therapy of staphylococcal osteoarticular infections.

Czekaj J, Dinh A, Moldovan A, Vaudaux P, Gras G, Hoffmeyer P, Lew D, Bernard L, Uçkay I.

Scand J Infect Dis. 2011 Dec;43(11-12):962-7. doi: 10.3109/00365548.2011.608082. Epub 2011 Sep 15.


Whole genome sequencing and complete genetic analysis reveals novel pathways to glycopeptide resistance in Staphylococcus aureus.

Renzoni A, Andrey DO, Jousselin A, Barras C, Monod A, Vaudaux P, Lew D, Kelley WL.

PLoS One. 2011;6(6):e21577. doi: 10.1371/journal.pone.0021577. Epub 2011 Jun 27.


Extracellular and intracellular bactericidal activities of XF-70 against small-colony variant hemB mutants of meticillin-susceptible and meticillin-resistant Staphylococcus aureus.

Vaudaux P, Huggler E, Rhys-Williams W, Love WG, Lew DP.

Int J Antimicrob Agents. 2011 Jun;37(6):576-9. doi: 10.1016/j.ijantimicag.2011.01.015. Epub 2011 Mar 16.


Impact of ciprofloxacin exposure on Staphylococcus aureus genomic alterations linked with emergence of rifampin resistance.

Didier JP, Villet R, Huggler E, Lew DP, Hooper DC, Kelley WL, Vaudaux P.

Antimicrob Agents Chemother. 2011 May;55(5):1946-52. doi: 10.1128/AAC.01407-10. Epub 2011 Feb 28.


Underestimation of vancomycin and teicoplanin MICs by broth microdilution leads to underdetection of glycopeptide-intermediate isolates of Staphylococcus aureus.

Vaudaux P, Huggler E, Bernard L, Ferry T, Renzoni A, Lew DP.

Antimicrob Agents Chemother. 2010 Sep;54(9):3861-70. doi: 10.1128/AAC.00269-10. Epub 2010 Jun 14.


Exploring innate glycopeptide resistance mechanisms in Staphylococcus aureus.

Renzoni A, Kelley WL, Vaudaux P, Cheung AL, Lew DP.

Trends Microbiol. 2010 Feb;18(2):55-6. doi: 10.1016/j.tim.2009.11.005. Epub 2009 Dec 11. Review. No abstract available.


Risk factors for treatment failure in orthopedic device-related methicillin-resistant Staphylococcus aureus infection.

Ferry T, Uçkay I, Vaudaux P, François P, Schrenzel J, Harbarth S, Laurent F, Bernard L, Vandenesch F, Etienne J, Hoffmeyer P, Lew D.

Eur J Clin Microbiol Infect Dis. 2010 Feb;29(2):171-80. doi: 10.1007/s10096-009-0837-y. Epub 2009 Nov 28.


Comparative activity of oritavancin against meticillin-resistant Staphylococcus aureus (MRSA) bloodstream isolates from Geneva University Hospital.

Vaudaux P, Huggler E, Arhin FF, Moeck G, Renzoni A, Lew DP.

Int J Antimicrob Agents. 2009 Dec;34(6):540-3. doi: 10.1016/j.ijantimicag.2009.07.016. Epub 2009 Sep 9.


Increased uptake and improved intracellular survival of a teicoplanin-resistant mutant of methicillin-resistant Staphylococcus aureus in non-professional phagocytes.

Renzoni A, Huggler E, Kelley WL, Lew D, Vaudaux P.

Chemotherapy. 2009;55(3):183-8. doi: 10.1159/000215304. Epub 2009 Apr 30.


Transcriptomic and metabolic responses of Staphylococcus aureus exposed to supra-physiological temperatures.

Fleury B, Kelley WL, Lew D, Götz F, Proctor RA, Vaudaux P.

BMC Microbiol. 2009 Apr 22;9:76. doi: 10.1186/1471-2180-9-76.


Comparison of tigecycline and vancomycin for treatment of experimental foreign-body infection due to methicillin-resistant Staphylococcus aureus.

Vaudaux P, Fleury B, Gjinovci A, Huggler E, Tangomo-Bento M, Lew DP.

Antimicrob Agents Chemother. 2009 Jul;53(7):3150-2. doi: 10.1128/AAC.01612-08. Epub 2009 Apr 13.


Identification by genomic and genetic analysis of two new genes playing a key role in intermediate glycopeptide resistance in Staphylococcus aureus.

Renzoni A, Kelley WL, Barras C, Monod A, Huggler E, François P, Schrenzel J, Studer R, Vaudaux P, Lew DP.

Antimicrob Agents Chemother. 2009 Mar;53(3):903-11. doi: 10.1128/AAC.01287-08. Epub 2008 Dec 22.


Foreign body infections due to Staphylococcus epidermidis.

Uçkay I, Pittet D, Vaudaux P, Sax H, Lew D, Waldvogel F.

Ann Med. 2009;41(2):109-19. doi: 10.1080/07853890802337045. Review.


Vancomycin-induced DRESS syndrome in a female patient.

Vauthey L, Uçkay I, Abrassart S, Bernard L, Assal M, Ferry T, Djordjevic M, Roussos C, Vaudaux P.

Pharmacology. 2008;82(2):138-41. doi: 10.1159/000142729. Epub 2008 Jul 8.


A global view of Staphylococcus aureus whole genome expression upon internalization in human epithelial cells.

Garzoni C, Francois P, Huyghe A, Couzinet S, Tapparel C, Charbonnier Y, Renzoni A, Lucchini S, Lew DP, Vaudaux P, Kelley WL, Schrenzel J.

BMC Genomics. 2007 Jun 14;8:171.


Inactivation of a subpopulation of human neutrophils by exposure to ultrahigh-molecular-weight polyethylene wear debris.

Bernard L, Vaudaux P, Huggler E, Stern R, Fréhel C, Francois P, Lew D, Hoffmeyer P.

FEMS Immunol Med Microbiol. 2007 Apr;49(3):425-32. Epub 2007 Mar 2.


Intracellular residency is frequently associated with recurrent Staphylococcus aureus rhinosinusitis.

Plouin-Gaudon I, Clement S, Huggler E, Chaponnier C, François P, Lew D, Schrenzel J, Vaudaux P, Lacroix JS.

Rhinology. 2006 Dec;44(4):249-54.


Exploring glycopeptide-resistance in Staphylococcus aureus: a combined proteomics and transcriptomics approach for the identification of resistance-related markers.

Scherl A, François P, Charbonnier Y, Deshusses JM, Koessler T, Huyghe A, Bento M, Stahl-Zeng J, Fischer A, Masselot A, Vaezzadeh A, Gallé F, Renzoni A, Vaudaux P, Lew D, Zimmermann-Ivol CG, Binz PA, Sanchez JC, Hochstrasser DF, Schrenzel J.

BMC Genomics. 2006 Nov 22;7:296.


Staphylococcus aureus small colony variants: difficult to diagnose and difficult to treat.

Vaudaux P, Kelley WL, Lew DP.

Clin Infect Dis. 2006 Oct 15;43(8):968-70. Epub 2006 Sep 8. No abstract available.


Transcriptomic and functional analysis of an autolysis-deficient, teicoplanin-resistant derivative of methicillin-resistant Staphylococcus aureus.

Renzoni A, Barras C, François P, Charbonnier Y, Huggler E, Garzoni C, Kelley WL, Majcherczyk P, Schrenzel J, Lew DP, Vaudaux P.

Antimicrob Agents Chemother. 2006 Sep;50(9):3048-61.


Tolerance of staphylococci to bactericidal antibiotics.

Vaudaux P, Lew DP.

Injury. 2006 May;37 Suppl 2:S15-9.


Intensive therapy with ceftobiprole medocaril of experimental foreign-body infection by methicillin-resistant Staphylococcus aureus.

Vaudaux P, Gjinovci A, Bento M, Li D, Schrenzel J, Lew DP.

Antimicrob Agents Chemother. 2005 Sep;49(9):3789-93.


Evidence of an intracellular reservoir in the nasal mucosa of patients with recurrent Staphylococcus aureus rhinosinusitis.

Clement S, Vaudaux P, Francois P, Schrenzel J, Huggler E, Kampf S, Chaponnier C, Lew D, Lacroix JS.

J Infect Dis. 2005 Sep 15;192(6):1023-8. Epub 2005 Aug 9.


Use of an automated multiple-locus, variable-number tandem repeat-based method for rapid and high-throughput genotyping of Staphylococcus aureus isolates.

Francois P, Huyghe A, Charbonnier Y, Bento M, Herzig S, Topolski I, Fleury B, Lew D, Vaudaux P, Harbarth S, van Leeuwen W, van Belkum A, Blanc DS, Pittet D, Schrenzel J.

J Clin Microbiol. 2005 Jul;43(7):3346-55.


A generic approach for the design of whole-genome oligoarrays, validated for genomotyping, deletion mapping and gene expression analysis on Staphylococcus aureus.

Charbonnier Y, Gettler B, François P, Bento M, Renzoni A, Vaudaux P, Schlegel W, Schrenzel J.

BMC Genomics. 2005 Jun 17;6:95.


Fibrinogen and fibronectin binding cooperate for valve infection and invasion in Staphylococcus aureus experimental endocarditis.

Que YA, Haefliger JA, Piroth L, François P, Widmer E, Entenza JM, Sinha B, Herrmann M, Francioli P, Vaudaux P, Moreillon P.

J Exp Med. 2005 May 16;201(10):1627-35.


The inhibition of neutrophil antibacterial activity by ultra-high molecular weight polyethylene particles.

Bernard L, Vaudaux P, Merle C, Stern R, Huggler E, Lew D, Hoffmeyer P.

Biomaterials. 2005 Sep;26(27):5552-7.


Induction of fibronectin adhesins in quinolone-resistant Staphylococcus aureus by subinhibitory levels of ciprofloxacin or by sigma B transcription factor activity is mediated by two separate pathways.

Li D, Renzoni A, Estoppey T, Bisognano C, Francois P, Kelley WL, Lew DP, Schrenzel J, Vaudaux P.

Antimicrob Agents Chemother. 2005 Mar;49(3):916-24.


Nosocomial bacteraemia caused by Staphylococcus aureus.

Vaudaux P, Schrenzel J.

Lancet. 2004 Aug 21-27;364(9435):644-5. No abstract available.


Modulation of fibronectin adhesins and other virulence factors in a teicoplanin-resistant derivative of methicillin-resistant Staphylococcus aureus.

Renzoni A, Francois P, Li D, Kelley WL, Lew DP, Vaudaux P, Schrenzel J.

Antimicrob Agents Chemother. 2004 Aug;48(8):2958-65.


A novel multiplex real-time PCR assay for rapid typing of major staphylococcal cassette chromosome mec elements.

Francois P, Renzi G, Pittet D, Bento M, Lew D, Harbarth S, Vaudaux P, Schrenzel J.

J Clin Microbiol. 2004 Jul;42(7):3309-12.


Comparative analysis and validation of different assays for glycopeptide susceptibility among methicillin-resistant Staphylococcus aureus strains.

Bernard L, Vaudaux P, Rohner P, Huggler E, Armanet M, Pittet D, Lew DP, Schrenzel J.

J Microbiol Methods. 2004 May;57(2):231-9.


A recA-LexA-dependent pathway mediates ciprofloxacin-induced fibronectin binding in Staphylococcus aureus.

Bisognano C, Kelley WL, Estoppey T, Francois P, Schrenzel J, Li D, Lew DP, Hooper DC, Cheung AL, Vaudaux P.

J Biol Chem. 2004 Mar 5;279(10):9064-71. Epub 2003 Dec 29.


Trends in the treatment of orthopaedic prosthetic infections.

Bernard L, Hoffmeyer P, Assal M, Vaudaux P, Schrenzel J, Lew D.

J Antimicrob Chemother. 2004 Feb;53(2):127-9. Epub 2003 Dec 19. Review.


Comparison of fluorescence and resonance light scattering for highly sensitive microarray detection of bacterial pathogens.

Francois P, Bento M, Vaudaux P, Schrenzel J.

J Microbiol Methods. 2003 Dec;55(3):755-62.


Effect of vancomycin therapy for osteomyelitis on colonization by methicillin-resistant Staphylococcus aureus: lack of emergence of glycopeptide resistance.

Bernard L, Vaudaux P, Vuagnat A, Stern R, Rohner P, Pittet D, Schrenzel J, Hoffmeyer P; Osteomyelitis Study Group.

Infect Control Hosp Epidemiol. 2003 Sep;24(9):650-4.


Comparative efficacy of daptomycin and vancomycin in the therapy of experimental foreign body infection due to Staphylococcus aureus.

Vaudaux P, Francois P, Bisognano C, Li D, Lew DP, Schrenzel J.

J Antimicrob Chemother. 2003 Jul;52(1):89-95. Epub 2003 May 29.


Lack of biofilm contribution to bacterial colonisation in an experimental model of foreign body infection by Staphylococcus aureus and Staphylococcus epidermidis.

Francois P, Tu Quoc PH, Bisognano C, Kelley WL, Lew DP, Schrenzel J, Cramton SE, Götz F, Vaudaux P.

FEMS Immunol Med Microbiol. 2003 Mar 20;35(2):135-40.


Rapid detection of methicillin-resistant Staphylococcus aureus directly from sterile or nonsterile clinical samples by a new molecular assay.

Francois P, Pittet D, Bento M, Pepey B, Vaudaux P, Lew D, Schrenzel J.

J Clin Microbiol. 2003 Jan;41(1):254-60.


Increased expression of clumping factor and fibronectin-binding proteins by hemB mutants of Staphylococcus aureus expressing small colony variant phenotypes.

Vaudaux P, Francois P, Bisognano C, Kelley WL, Lew DP, Schrenzel J, Proctor RA, McNamara PJ, Peters G, Von Eiff C.

Infect Immun. 2002 Oct;70(10):5428-37.

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