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Items: 30


Role of tissue factor in Mycobacterium tuberculosis-induced inflammation and disease pathogenesis.

Kothari H, Keshava S, Vatsyayan R, Mackman N, Rao LV, Pendurthi UR.

PLoS One. 2014 Dec 2;9(12):e114141. doi: 10.1371/journal.pone.0114141. eCollection 2014.


Inactivation of factor VIIa by antithrombin in vitro, ex vivo and in vivo: role of tissue factor and endothelial cell protein C receptor.

Vatsyayan R, Kothari H, Mackman N, Pendurthi UR, Rao LV.

PLoS One. 2014 Aug 7;9(8):e103505. doi: 10.1371/journal.pone.0103505. eCollection 2014.


Proteomic analysis of signaling network regulation in renal cell carcinomas with differential hypoxia-inducible factor-2α expression.

Nagaprashantha LD, Talamantes T, Singhal J, Guo J, Vatsyayan R, Rauniyar N, Awasthi S, Singhal SS, Prokai L.

PLoS One. 2013 Aug 5;8(8):e71654. doi: 10.1371/journal.pone.0071654. Print 2013.


4-Hydroxy-2-nonenal enhances tissue factor activity in human monocytic cells via p38 mitogen-activated protein kinase activation-dependent phosphatidylserine exposure.

Vatsyayan R, Kothari H, Pendurthi UR, Rao LV.

Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1601-11. doi: 10.1161/ATVBAHA.113.300972. Epub 2013 May 2.


Endothelial cell protein C receptor-mediated redistribution and tissue-level accumulation of factor VIIa.

Clark CA, Vatsyayan R, Hedner U, Esmon CT, Pendurthi UR, Rao LV.

J Thromb Haemost. 2012 Nov;10(11):2383-91. doi: 10.1111/j.1538-7836.2012.04917.x.


Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma.

Singhal J, Nagaprashantha LD, Vatsyayan R, Ashutosh, Awasthi S, Singhal SS.

Cancer Prev Res (Phila). 2012 Mar;5(3):473-83. doi: 10.1158/1940-6207.CAPR-11-0318. Epub 2011 Dec 15.


The expression and function of vascular endothelial growth factor in retinal pigment epithelial (RPE) cells is regulated by 4-hydroxynonenal (HNE) and glutathione S-transferaseA4-4.

Vatsyayan R, Lelsani PC, Chaudhary P, Kumar S, Awasthi S, Awasthi YC.

Biochem Biophys Res Commun. 2012 Jan 6;417(1):346-51. doi: 10.1016/j.bbrc.2011.11.113. Epub 2011 Dec 1.


Nutlin-3 enhances sorafenib efficacy in renal cell carcinoma.

Vatsyayan R, Singhal J, Nagaprashantha LD, Awasthi S, Singhal SS.

Mol Carcinog. 2013 Jan;52(1):39-48. doi: 10.1002/mc.20875. Epub 2011 Oct 17.


RLIP76, a glutathione-conjugate transporter, plays a major role in the pathogenesis of metabolic syndrome.

Singhal J, Nagaprashantha L, Vatsyayan R, Awasthi S, Singhal SS.

PLoS One. 2011;6(9):e24688. doi: 10.1371/journal.pone.0024688. Epub 2011 Sep 13.


Anti-cancer effects of novel flavonoid vicenin-2 as a single agent and in synergistic combination with docetaxel in prostate cancer.

Nagaprashantha LD, Vatsyayan R, Singhal J, Fast S, Roby R, Awasthi S, Singhal SS.

Biochem Pharmacol. 2011 Nov 1;82(9):1100-9. doi: 10.1016/j.bcp.2011.07.078. Epub 2011 Jul 23.


Targeting p53-null neuroblastomas through RLIP76.

Singhal J, Yadav S, Nagaprashantha LD, Vatsyayan R, Singhal SS, Awasthi S.

Cancer Prev Res (Phila). 2011 Jun;4(6):879-89. doi: 10.1158/1940-6207.CAPR-11-0025. Epub 2011 Mar 16.


2'-hydroxyflavanone inhibits proliferation, tumor vascularization and promotes normal differentiation in VHL-mutant renal cell carcinoma.

Nagaprashantha LD, Vatsyayan R, Singhal J, Lelsani P, Prokai L, Awasthi S, Singhal SS.

Carcinogenesis. 2011 Apr;32(4):568-75. doi: 10.1093/carcin/bgr021. Epub 2011 Feb 8.


Glutathione-conjugate transport by RLIP76 is required for clathrin-dependent endocytosis and chemical carcinogenesis.

Singhal SS, Wickramarachchi D, Yadav S, Singhal J, Leake K, Vatsyayan R, Chaudhary P, Lelsani P, Suzuki S, Yang S, Awasthi YC, Awasthi S.

Mol Cancer Ther. 2011 Jan;10(1):16-28. doi: 10.1158/1535-7163.MCT-10-0699.


Role of 4-hydroxynonenal in epidermal growth factor receptor-mediated signaling in retinal pigment epithelial cells.

Vatsyayan R, Chaudhary P, Sharma A, Sharma R, Rao Lelsani PC, Awasthi S, Awasthi YC.

Exp Eye Res. 2011 Feb;92(2):147-54. doi: 10.1016/j.exer.2010.11.010. Epub 2010 Dec 4.


The sensors and regulators of cell-matrix surveillance in anoikis resistance of tumors.

Nagaprashantha LD, Vatsyayan R, Lelsani PC, Awasthi S, Singhal SS.

Int J Cancer. 2011 Feb 15;128(4):743-52. doi: 10.1002/ijc.25725. Epub 2010 Dec 7. Review.


Mechanisms of 4-hydroxy-2-nonenal induced pro- and anti-apoptotic signaling.

Chaudhary P, Sharma R, Sharma A, Vatsyayan R, Yadav S, Singhal SS, Rauniyar N, Prokai L, Awasthi S, Awasthi YC.

Biochemistry. 2010 Jul 27;49(29):6263-75. doi: 10.1021/bi100517x.


Role of lipid peroxidation in cellular responses to D,L-sulforaphane, a promising cancer chemopreventive agent.

Sharma R, Sharma A, Chaudhary P, Pearce V, Vatsyayan R, Singh SV, Awasthi S, Awasthi YC.

Biochemistry. 2010 Apr 13;49(14):3191-202. doi: 10.1021/bi100104e.


Physiological and pharmacological significance of glutathione-conjugate transport.

Awasthi YC, Chaudhary P, Vatsyayan R, Sharma A, Awasthi S, Sharma R.

J Toxicol Environ Health B Crit Rev. 2009 Aug;12(7):540-51. doi: 10.1080/10937400903358975. Review.


RLIP76: a versatile transporter and an emerging target for cancer therapy.

Vatsyayan R, Lelsani PC, Awasthi S, Singhal SS.

Biochem Pharmacol. 2010 Jun 15;79(12):1699-705. doi: 10.1016/j.bcp.2010.01.016. Epub 2010 Jan 25. Review.


A central role of RLIP76 in regulation of glycemic control.

Awasthi S, Singhal SS, Yadav S, Singhal J, Vatsyayan R, Zajac E, Luchowski R, Borvak J, Gryczynski K, Awasthi YC.

Diabetes. 2010 Mar;59(3):714-25. doi: 10.2337/db09-0911. Epub 2009 Dec 10.


Rlip76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancer.

Singhal SS, Sehrawat A, Sahu M, Singhal P, Vatsyayan R, Rao Lelsani PC, Yadav S, Awasthi S.

Int J Cancer. 2010 Mar 15;126(6):1327-38. doi: 10.1002/ijc.24767.


Role of RLIP76 in doxorubicin resistance in lung cancer.

Vatsyayan R, Chaudhary P, Lelsani PC, Singhal P, Awasthi YC, Awasthi S, Singhal SS.

Int J Oncol. 2009 Jun;34(6):1505-11. Review.


Increased expression of cdc2 inhibits transport function of RLIP76 and promotes apoptosis.

Singhal SS, Yadav S, Vatsyayan R, Chaudhary P, Borvak J, Singhal J, Awasthi S.

Cancer Lett. 2009 Oct 8;283(2):152-8. doi: 10.1016/j.canlet.2009.03.033. Epub 2009 Apr 17.


Sterol 24-C-methyltransferase: an enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformans.

Nes WD, Zhou W, Ganapathy K, Liu J, Vatsyayan R, Chamala S, Hernandez K, Miranda M.

Arch Biochem Biophys. 2009 Jan 15;481(2):210-8. doi: 10.1016/ Epub 2008 Nov 8.


4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells.

Sharma A, Sharma R, Chaudhary P, Vatsyayan R, Pearce V, Jeyabal PV, Zimniak P, Awasthi S, Awasthi YC.

Arch Biochem Biophys. 2008 Dec 15;480(2):85-94. doi: 10.1016/ Epub 2008 Oct 7.


Molecular probing of the Saccharomyces cerevisiae sterol 24-C methyltransferase reveals multiple amino acid residues involved with C2-transfer activity.

Ganapathy K, Jones CW, Stephens CM, Vatsyayan R, Marshall JA, Nes WD.

Biochim Biophys Acta. 2008 Jun-Jul;1781(6-7):344-51. doi: 10.1016/j.bbalip.2008.04.015. Epub 2008 May 8.


High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias.

Li H, Black PN, Chokshi A, Sandoval-Alvarez A, Vatsyayan R, Sealls W, DiRusso CC.

J Lipid Res. 2008 Jan;49(1):230-44. Epub 2007 Oct 10.


Molecular cloning and biochemical characterization of Leishmania donovani serine hydroxymethyltransferase.

Vatsyayan R, Roy U.

Protein Expr Purif. 2007 Apr;52(2):433-40. Epub 2006 Oct 26.


Arylanthranilodinitriles: a new biaryl class of antileishmanial agents.

Singh FV, Vatsyayan R, Roy U, Goel A.

Bioorg Med Chem Lett. 2006 May 15;16(10):2734-7. Epub 2006 Feb 28.


6-Aryl-4-methylsulfanyl-2H-pyran-2-one-3-carbonitriles as PPAR-gamma activators.

Sharon A, Pratap R, Vatsyayan R, Maulik PR, Roy U, Goel A, Ram VJ.

Bioorg Med Chem Lett. 2005 Jul 15;15(14):3356-60.


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