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Rev Med Chir Soc Med Nat Iasi. 2013 Apr-Jun;117(2):476-82.

Viral meningitis admitted to an infectious diseases hospital: a retrospective case series.

Author information

1
Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa" - Iaşi.

Abstract

Given its epidemic potential and development of severe forms of disease, viral meningitis (VM) is a serious public health problem.

AIM:

to characterize the main clinical, epidemiologic features, the etiology and treatment of VM cases admitted to the Iasi Infectious Diseases Hospital, in 2012.

MATERIAL AND METHODS:

We retrospectively analyzed the medical records of the patients admitted for viral meningitis at the Iasi "St. Parascheva" Infectious Diseases Hospital in the interval January 1- December 31, 2012 (98 cases). The etiologic diagnosis was made by determining the IgM/IgG antibodies against Coxsackie virus and/or West Nile virus in blood/CSF.

RESULTS:

There was a fourfold increase in the number of cases as compared to the average for the years 2009-2011. Most cases (73.5%) were children aged 1 to 14 years. 61.8% of patients were males, 51.7% from urban areas. The most common symptom was headache (85.7%), followed by fever (77.6%), and vomiting (66.3%). Neck stiffness was absent in 28.6% cases. In43.5% of the 39 patients serologically investigated a Coxsackie virus infection was confirmed and 1/20 was positive for West Nile virus; three varicella-zoster virus infections and one mumps infection were diagnosed clinically. 68.3% of the patients received first-line antibiotic treatment.

CONCLUSIONS:

The illness mainly affected children, fever and neck stiffness being sometimes absent. The etiology was known in 22.4% of cases; enter viruses being the most frequent causative agent. Most patients received antibiotic therapy. The course was favorable in all cases.

PMID:
24340533
[Indexed for MEDLINE]

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