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Items: 1 to 50 of 55

1.

Beneficial effects of lysosome-modulating and other pharmacological and nanocarrier agents on amyloid-beta-treated cells.

Kanazirska MV, Fuchs PM, Chen L, Lal S, Verma J, Vassilev PM.

Curr Pharm Biotechnol. 2012 Dec;13(15):2761-7.

PMID:
23072393
2.

The cation channel mucolipin-1 is a bifunctional protein that facilitates membrane remodeling via its serine lipase domain.

LaPlante JM, Falardeau JL, Brown EM, Slaugenhaupt SA, Vassilev PM.

Exp Cell Res. 2011 Apr 1;317(6):691-705. doi: 10.1016/j.yexcr.2011.01.008. Epub 2011 Jan 20.

3.

Calcium-sensing receptor stimulates secretion of an interferon-gamma-induced monokine (CXCL10) and monocyte chemoattractant protein-3 in immortalized GnRH neurons.

Bandyopadhyay S, Jeong KH, Hansen JT, Vassilev PM, Brown EM, Chattopadhyay N.

J Neurosci Res. 2007 Mar;85(4):882-95.

PMID:
17285630
4.

Calcium receptor stimulates chemotaxis and secretion of MCP-1 in GnRH neurons in vitro: potential impact on reduced GnRH neuron population in CaR-null mice.

Chattopadhyay N, Jeong KH, Yano S, Huang S, Pang JL, Ren X, Terwilliger E, Kaiser UB, Vassilev PM, Pollak MR, Brown EM.

Am J Physiol Endocrinol Metab. 2007 Feb;292(2):E523-32. Epub 2006 Sep 26.

5.

Lysosomal exocytosis is impaired in mucolipidosis type IV.

LaPlante JM, Sun M, Falardeau J, Dai D, Brown EM, Slaugenhaupt SA, Vassilev PM.

Mol Genet Metab. 2006 Dec;89(4):339-48. Epub 2006 Aug 17.

PMID:
16914343
6.

Functional links between mucolipin-1 and Ca2+-dependent membrane trafficking in mucolipidosis IV.

LaPlante JM, Ye CP, Quinn SJ, Goldin E, Brown EM, Slaugenhaupt SA, Vassilev PM.

Biochem Biophys Res Commun. 2004 Oct 1;322(4):1384-91.

PMID:
15336987
7.

Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epithelia.

Luo Y, Vassilev PM, Li X, Kawanabe Y, Zhou J.

Mol Cell Biol. 2003 Apr;23(7):2600-7.

8.

Identification and characterization of the single channel function of human mucolipin-1 implicated in mucolipidosis type IV, a disorder affecting the lysosomal pathway.

LaPlante JM, Falardeau J, Sun M, Kanazirska M, Brown EM, Slaugenhaupt SA, Vassilev PM.

FEBS Lett. 2002 Dec 4;532(1-2):183-7.

9.

Single-channel activities of the human epithelial Ca2+ transport proteins CaT1 and CaT2.

Vassilev PM, Peng JB, Hediger MA, Brown EM.

J Membr Biol. 2001 Nov 15;184(2):113-20.

PMID:
11719848
10.

Transport function of the naturally occurring pathogenic polycystin-2 mutant, R742X.

Chen XZ, Segal Y, Basora N, Guo L, Peng JB, Babakhanlou H, Vassilev PM, Brown EM, Hediger MA, Zhou J.

Biochem Biophys Res Commun. 2001 Apr 20;282(5):1251-6.

PMID:
11302751
11.

Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney disease.

Vassilev PM, Guo L, Chen XZ, Segal Y, Peng JB, Basora N, Babakhanlou H, Cruger G, Kanazirska M, Ye Cp, Brown EM, Hediger MA, Zhou J.

Biochem Biophys Res Commun. 2001 Mar 23;282(1):341-50.

PMID:
11264013
12.

Expression of extracellular calcium-sensing receptor in human osteoblastic MG-63 cell line.

Yamaguchi T, Chattopadhyay N, Kifor O, Ye C, Vassilev PM, Sanders JL, Brown EM.

Am J Physiol Cell Physiol. 2001 Feb;280(2):C382-93.

13.

Inhibition of CaT1 channel activity by a noncompetitive IP3 antagonist.

Vassilev PM, Peng JB, Johnson J, Hediger MA, Brown EM.

Biochem Biophys Res Commun. 2001 Jan 12;280(1):145-50.

PMID:
11162491
14.

Human calcium transport protein CaT1.

Peng JB, Chen XZ, Berger UV, Weremowicz S, Morton CC, Vassilev PM, Brown EM, Hediger MA.

Biochem Biophys Res Commun. 2000 Nov 19;278(2):326-32.

PMID:
11097838
16.

A rat kidney-specific calcium transporter in the distal nephron.

Peng JB, Chen XZ, Berger UV, Vassilev PM, Brown EM, Hediger MA.

J Biol Chem. 2000 Sep 8;275(36):28186-94.

17.
18.
19.

Extracellular calcium-sensing receptor induces cellular proliferation and activation of a nonselective cation channel in U373 human astrocytoma cells.

Chattopadhyay N, Ye CP, Yamaguchi T, Kerner R, Vassilev PM, Brown EM.

Brain Res. 1999 Dec 18;851(1-2):116-24.

PMID:
10642834
20.

Polycystin-L is a calcium-regulated cation channel permeable to calcium ions.

Chen XZ, Vassilev PM, Basora N, Peng JB, Nomura H, Segal Y, Brown EM, Reeders ST, Hediger MA, Zhou J.

Nature. 1999 Sep 23;401(6751):383-6.

PMID:
10517637
21.

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

Hartley DM, Walsh DM, Ye CP, Diehl T, Vasquez S, Vassilev PM, Teplow DB, Selkoe DJ.

J Neurosci. 1999 Oct 15;19(20):8876-84.

22.
23.

Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorption.

Peng JB, Chen XZ, Berger UV, Vassilev PM, Tsukaguchi H, Brown EM, Hediger MA.

J Biol Chem. 1999 Aug 6;274(32):22739-46.

24.

The extracellular calcium-sensing receptor is expressed in rat microglia and modulates an outward K+ channel.

Chattopadhyay N, Ye C, Yamaguchi T, Nakai M, Kifor O, Vassilev PM, Nishimura RN, Brown EM.

J Neurochem. 1999 May;72(5):1915-22.

25.

Evidence for extracellular calcium-sensing receptor mediated opening of an outward K+ channel in a human astrocytoma cell line (U87).

Chattopadhyay N, Ye CP, Yamaguchi T, Vassilev PM, Brown EM.

Glia. 1999 Mar;26(1):64-72.

PMID:
10088673
26.

G-protein-coupled, extracellular Ca(2+)-sensing receptor: a versatile regulator of diverse cellular functions.

Brown EM, Vassilev PM, Quinn S, Hebert SC.

Vitam Horm. 1999;55:1-71. Review. No abstract available.

PMID:
9949679
27.

Extracellular calcium-sensing receptor in rat oligodendrocytes: expression and potential role in regulation of cellular proliferation and an outward K+ channel.

Chattopadhyay N, Ye CP, Yamaguchi T, Kifor O, Vassilev PM, Nishimura R, Brown EM.

Glia. 1998 Dec;24(4):449-58.

PMID:
9814825
28.

The calcium-sensing receptor (CaR) permits Ca2+ to function as a versatile extracellular first messenger.

Brown EM, Chattopadhyay N, Vassilev PM, Hebert SC.

Recent Prog Horm Res. 1998;53:257-80; discussion 280-1. Review.

PMID:
9769711
29.

Calcium-sensing receptor: roles in and beyond systemic calcium homeostasis.

Chattopadhyay N, Vassilev PM, Brown EM.

Biol Chem. 1997 Aug;378(8):759-68. Review.

PMID:
9377470
30.

Targeted inactivation of alphai2 or alphai3 disrupts activation of the cardiac muscarinic K+ channel, IK+Ach, in intact cells.

Sowell MO, Ye C, Ricupero DA, Hansen S, Quinn SJ, Vassilev PM, Mortensen RM.

Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):7921-6.

31.

Calcium-sensing receptor in the rat hippocampus: a developmental study.

Chattopadhyay N, Legradi G, Bai M, Kifor O, Ye C, Vassilev PM, Brown EM, Lechan RM.

Brain Res Dev Brain Res. 1997 May 20;100(1):13-21.

PMID:
9174241
32.

Assessment of frequency-dependent alterations in the level of extracellular Ca2+ in the synaptic cleft.

Vassilev PM, Mitchel J, Vassilev M, Kanazirska M, Brown EM.

Biophys J. 1997 May;72(5):2103-16.

33.

Expression of extracellular calcium-sensing receptor by human lens epithelial cells.

Chattopadhyay N, Ye C, Singh DP, Kifor O, Vassilev PM, Shinohara T, Chylack LT Jr, Brown EM.

Biochem Biophys Res Commun. 1997 Apr 28;233(3):801-5. Erratum in: Biochem Biophys Res Commun 1997 Aug 18;237(2):481.

PMID:
9168937
34.

Cao-sensing receptor (CaR)-mediated activation of K+ channels is blunted in CaR gene-deficient mouse neurons.

Vassilev PM, Ho-Pao CL, Kanazirska MP, Ye C, Hong K, Seidman CE, Seidman JG, Brown EM.

Neuroreport. 1997 Apr 14;8(6):1411-6.

PMID:
9172145
35.

Voltage-dependent effect of Al3+ on channel activities in hippocampal neurons.

Kanazirska M, Vassilev PP, Birzon SY, Vassilev PM.

Biochem Biophys Res Commun. 1997 Mar 6;232(1):84-7.

PMID:
9125157
36.

Amyloid-beta proteins activate Ca(2+)-permeable channels through calcium-sensing receptors.

Ye C, Ho-Pao CL, Kanazirska M, Quinn S, Rogers K, Seidman CE, Seidman JG, Brown EM, Vassilev PM.

J Neurosci Res. 1997 Mar 1;47(5):547-54.

PMID:
9067864
37.

A flickery block of a K+ channel mediated by extracellular Ca2+ and other agonists of the Ca2+-sensing receptors in dispersed bovine parathyroid cells.

Vassilev PM, Kanazirska MP, Ye C, Francis J, Hong K, Brown EM.

Biochem Biophys Res Commun. 1997 Jan 23;230(3):616-23.

PMID:
9015373
38.

Deficient cation channel regulation in neurons from mice with targeted disruption of the extracellular Ca2+-sensing receptor gene.

Ye C, Ho-Pao CL, Kanazirska M, Quinn S, Seidman CE, Seidman JG, Brown EM, Vassilev PM.

Brain Res Bull. 1997;44(1):75-84.

PMID:
9288833
39.

Agonists of the Ca(2+)-sensing receptor (CaR) activate nonselective cation channels in HEK293 cells stably transfected with the human CaR.

Ye C, Rogers K, Bai M, Quinn SJ, Brown EM, Vassilev PM.

Biochem Biophys Res Commun. 1996 Sep 13;226(2):572-9.

PMID:
8806675
40.

Modulation by polycationic Ca(2+)-sensing receptor agonists of nonselective cation channels in rat hippocampal neurons.

Ye C, Kanazirska M, Quinn S, Brown EM, Vassilev PM.

Biochem Biophys Res Commun. 1996 Jul 5;224(1):271-80.

PMID:
8694826
41.

Calcium ions as extracellular messengers.

Brown EM, Vassilev PM, Hebert SC.

Cell. 1995 Dec 1;83(5):679-82. Review. No abstract available.

42.

Intracellular Ca(2+)-activated K+ channels modulated by variations in extracellular Ca2+ in dispersed bovine parathyroid cells.

Kanazirska MP, Vassilev PM, Ye CP, Francis JE, Brown EM.

Endocrinology. 1995 May;136(5):2238-43.

PMID:
7720673
43.

Cloning and expression of an inwardly rectifying ATP-regulated potassium channel.

Ho K, Nichols CG, Lederer WJ, Lytton J, Vassilev PM, Kanazirska MV, Hebert SC.

Nature. 1993 Mar 4;362(6415):31-8.

PMID:
7680431
44.

Single K+ channels in adrenal zona glomerulosa cells. II. Inhibition by angiotensin II.

Kanazirska MV, Vassilev PM, Quinn SJ, Tillotson DL, Williams GH.

Am J Physiol. 1992 Oct;263(4 Pt 1):E760-5.

PMID:
1415697
45.

K+ channels in adrenal zona glomerulosa cells. I. Characterization of distinct channel types.

Vassilev PM, Kanazirska MV, Quinn SJ, Tillotson DL, Williams GH.

Am J Physiol. 1992 Oct;263(4 Pt 1):E752-9.

PMID:
1415696
46.

ANG II blocks potassium currents in zona glomerulosa cells from rat, bovine, and human adrenals.

Brauneis U, Vassilev PM, Quinn SJ, Williams GH, Tillotson DL.

Am J Physiol. 1991 May;260(5 Pt 1):E772-9.

PMID:
2035634
47.
48.

Reconstitution of membrane molecular mechanisms in bilayer lipid membranes and patch-clamp bilayers.

Vassilev PM, Tien HT.

Subcell Biochem. 1989;14:97-143. Review. No abstract available.

PMID:
2655201
49.

Identification of an intracellular peptide segment involved in sodium channel inactivation.

Vassilev PM, Scheuer T, Catterall WA.

Science. 1988 Sep 23;241(4873):1658-61.

PMID:
2458625
50.

Ca2+ channels from brain microsomal membranes reconstituted in patch-clamped bilayers.

Vassilev PM, Kanazirska MP, Tien HT.

Biochim Biophys Acta. 1987 Feb 26;897(2):324-30.

PMID:
2434130

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