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Items: 1 to 50 of 89

1.

The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress.

Moreno Leon L, Gautier M, Allan R, Ilié M, Nottet N, Pons N, Paquet A, Lebrigand K, Truchi M, Fassy J, Magnone V, Kinnebrew G, Radovich M, Cheok MH, Barbry P, Vassaux G, Marquette CH, Ponzio G, Ivan M, Pottier N, Hofman P, Mari B, Rezzonico R.

Oncogene. 2019 Aug 15. doi: 10.1038/s41388-019-0935-y. [Epub ahead of print]

PMID:
31417181
2.

The Long Noncoding RNA DNM3OS Is a Reservoir of FibromiRs with Major Functions in Lung Fibroblast Response to TGF-β and Pulmonary Fibrosis.

Savary G, Dewaeles E, Diazzi S, Buscot M, Nottet N, Fassy J, Courcot E, Henaoui IS, Lemaire J, Martis N, Van der Hauwaert C, Pons N, Magnone V, Leroy S, Hofman V, Plantier L, Lebrigand K, Paquet A, Lino Cardenas CL, Vassaux G, Hofman P, Günther A, Crestani B, Wallaert B, Rezzonico R, Brousseau T, Glowacki F, Bellusci S, Perrais M, Broly F, Barbry P, Marquette CH, Cauffiez C, Mari B, Pottier N.

Am J Respir Crit Care Med. 2019 Jul 15;200(2):184-198. doi: 10.1164/rccm.201807-1237OC.

PMID:
30964696
3.

Tetrafunctional Block Copolymers Promote Lung Gene Transfer in Newborn Piglets.

Caballero I, Riou M, Hacquin O, Chevaleyre C, Barc C, Pezant J, Pinard A, Fassy J, Rezzonico R, Mari B, Heuzé-Vourc'h N, Pitard B, Vassaux G.

Mol Ther Nucleic Acids. 2019 Jun 7;16:186-193. doi: 10.1016/j.omtn.2019.02.016. Epub 2019 Feb 26.

4.

Iodinated Contrast Agents Perturb Iodide Uptake by the Thyroid Independently of Free Iodide.

Vassaux G, Zwarthoed C, Signetti L, Guglielmi J, Compin C, Guigonis JM, Juhel T, Humbert O, Benisvy D, Pourcher T, Cambien B.

J Nucl Med. 2018 Jan;59(1):121-126. doi: 10.2967/jnumed.117.195685. Epub 2017 Oct 19.

5.

Single-Photon Emission Computed Tomography for Preclinical Assessment of Thyroid Radioiodide Uptake Following Various Combinations of Preparative Measures.

Zwarthoed C, Chatti K, Guglielmi J, Hichri M, Compin C, Darcourt J, Vassaux G, Benisvy D, Pourcher T, Cambien B.

Thyroid. 2016 Nov;26(11):1614-1622. Epub 2016 Aug 11.

PMID:
27349131
6.

Twelfth Annual Meeting of the French Society of Cell and Gene Therapy.

Verhoeyen E, Gomez S, Galy A, Ayuso E, Midoux P, Pucéat M, Vassaux G, Cordelier P.

Hum Gene Ther. 2016 Jul;27(7):555-8. doi: 10.1089/hum.2016.29031.eve. No abstract available.

PMID:
27428658
7.

The Promise of Gene Therapy for Pancreatic Cancer.

Vassaux G, Angelova A, Baril P, Midoux P, Rommelaere J, Cordelier P.

Hum Gene Ther. 2016 Feb;27(2):127-33. doi: 10.1089/hum.2015.141. Review.

PMID:
26603492
8.

Evaluation of tetrafunctional block copolymers as synthetic vectors for lung gene transfer.

Richard-Fiardo P, Hervouet C, Marsault R, Franken PR, Cambien B, Guglielmi J, Warnez-Soulie J, Darcourt J, Pourcher T, Colombani T, Haudebourg T, Peuziat P, Pitard B, Vassaux G.

Biomaterials. 2015 Mar;45:10-7. doi: 10.1016/j.biomaterials.2014.12.051. Epub 2015 Jan 13.

PMID:
25662490
9.

Calcium homeostasis in myogenic differentiation factor 1 (MyoD)-transformed, virally-transduced, skin-derived equine myotubes.

Fernandez-Fuente M, Terracciano CM, Martin-Duque P, Brown SC, Vassaux G, Piercy RJ.

PLoS One. 2014 Aug 22;9(8):e105971. doi: 10.1371/journal.pone.0105971. eCollection 2014.

10.

⁹⁹mTcO₄--, auger-mediated thyroid stunning: dosimetric requirements and associated molecular events.

Cambien B, Franken PR, Lamit A, Mauxion T, Richard-Fiardo P, Guglielmi J, Crescence L, Mari B, Pourcher T, Darcourt J, Bardiès M, Vassaux G.

PLoS One. 2014 Mar 24;9(3):e92729. doi: 10.1371/journal.pone.0092729. eCollection 2014.

11.

Adenovirus-mediated expression of myogenic differentiation factor 1 (MyoD) in equine and human dermal fibroblasts enables their conversion to caffeine-sensitive myotubes.

Fernandez-Fuente M, Martin-Duque P, Vassaux G, Brown SC, Muntoni F, Terracciano CM, Piercy RJ.

Neuromuscul Disord. 2014 Mar;24(3):250-8. doi: 10.1016/j.nmd.2013.11.009. Epub 2013 Nov 23.

PMID:
24342283
12.

RILES, a novel method for temporal analysis of the in vivo regulation of miRNA expression.

Ezzine S, Vassaux G, Pitard B, Barteau B, Malinge JM, Midoux P, Pichon C, Baril P.

Nucleic Acids Res. 2013 Nov;41(20):e192. doi: 10.1093/nar/gkt797. Epub 2013 Sep 5.

13.

Adrenal gland infection by serotype 5 adenovirus requires coagulation factors.

Tran L, Ouisse LH, Richard-Fiardo P, Franken PR, Darcourt J, Cornilleau G, Benihoud K, Vassaux G.

PLoS One. 2013 Apr 25;8(4):e62191. doi: 10.1371/journal.pone.0062191. Print 2013.

14.

Early Treg suppression by a listeriolysin-O-expressing E. coli vaccine in heterologous prime-boost vaccination against cancer.

Dai MS, Vassaux G, Xu M, You RI, Hsieh YF, Ouisse LH, Lo KY, Sytwu HK, Chao TY.

Vaccine. 2012 Nov 6;30(48):6903-11. doi: 10.1016/j.vaccine.2012.09.001. Epub 2012 Sep 14.

PMID:
22982404
15.

The immunogenicity of the tumor-associated antigen α-fetoprotein is enhanced by a fusion with a transmembrane domain.

Tran L, Judor JP, Gauttier V, Geist M, Hoffman C, Rooke R, Vassaux G, Conchon S.

J Biomed Biotechnol. 2012;2012:878657. doi: 10.1155/2012/878657. Epub 2012 Feb 21.

16.

Normalisation to blood activity is required for the accurate quantification of Na/I symporter ectopic expression by SPECT/CT in individual subjects.

Richard-Fiardo P, Franken PR, Lamit A, Marsault R, Guglielmi J, Cambien B, Graslin F, Lindenthal S, Darcourt J, Pourcher T, Vassaux G.

PLoS One. 2012;7(3):e34086. doi: 10.1371/journal.pone.0034086. Epub 2012 Mar 21.

17.

Differential biodistribution of oncolytic poxvirus administered systemically in an autochthonous model of hepatocellular carcinoma.

Baril P, Touchefeu Y, Cany J, Cherel Y, Thorne SH, Tran L, Conchon S, Vassaux G.

J Gene Med. 2011 Dec;13(12):692-701. doi: 10.1002/jgm.1624.

PMID:
22028274
18.

In vivo positron emission tomography imaging using the sodium iodide symporter as a reporter gene.

Tran L, Dartial N, Hindorf C, Vassaux G.

Methods Mol Biol. 2012;797:89-96. doi: 10.1007/978-1-61779-340-0_7.

PMID:
21948471
19.

Oncolytic viruses in radiation oncology.

Touchefeu Y, Vassaux G, Harrington KJ.

Radiother Oncol. 2011 Jun;99(3):262-70. doi: 10.1016/j.radonc.2011.05.078. Epub 2011 Jun 23. Review.

PMID:
21704402
20.

Telomerase-driven expression of the sodium iodide symporter (NIS) for in vivo radioiodide treatment of cancer: a new broad-spectrum NIS-mediated antitumor approach.

Riesco-Eizaguirre G, De la Vieja A, Rodríguez I, Miranda S, Martín-Duque P, Vassaux G, Santisteban P.

J Clin Endocrinol Metab. 2011 Sep;96(9):E1435-43. doi: 10.1210/jc.2010-2373. Epub 2011 Jun 22.

PMID:
21697253
21.

The use of molecular imaging of gene expression by radiotracers in gene therapy.

Richard-Fiardo P, Franken PR, Harrington KJ, Vassaux G, Cambien B.

Expert Opin Biol Ther. 2011 Oct;11(10):1273-85. doi: 10.1517/14712598.2011.588596. Epub 2011 Jun 2. Review.

PMID:
21635148
22.

Immunotherapy of hepatocellular carcinoma: is there a place for regulatory T-lymphocyte depletion?

Cany J, Tran L, Gauttier V, Judor JP, Vassaux G, Ferry N, Conchon S.

Immunotherapy. 2011 Apr;3(4 Suppl):32-4. doi: 10.2217/imt.11.29. Review.

PMID:
21524167
23.

AFP-specific immunotherapy impairs growth of autochthonous hepatocellular carcinoma in mice.

Cany J, Barteau B, Tran L, Gauttier V, Archambeaud I, Couty JP, Turlin B, Pitard B, Vassaux G, Ferry N, Conchon S.

J Hepatol. 2011 Jan;54(1):115-21. doi: 10.1016/j.jhep.2010.06.027. Epub 2010 Aug 26.

PMID:
20961645
24.

Review article: gene therapy, recent developments and future prospects in gastrointestinal oncology.

Touchefeu Y, Harrington KJ, Galmiche JP, Vassaux G.

Aliment Pharmacol Ther. 2010 Oct;32(8):953-68. doi: 10.1111/j.1365-2036.2010.04424.x. Epub 2010 Aug 15. Review.

25.

Therapeutic effect of sodium iodide symporter gene therapy combined with external beam radiotherapy and targeted drugs that inhibit DNA repair.

Hingorani M, White CL, Zaidi S, Pandha HS, Melcher AA, Bhide SA, Nutting CM, Syrigos KN, Vile RG, Vassaux G, Harrington KJ.

Mol Ther. 2010 Sep;18(9):1599-605. doi: 10.1038/mt.2010.120. Epub 2010 Jun 29.

26.

Delivery of Na/I symporter gene into skeletal muscle using nanobubbles and ultrasound: visualization of gene expression by PET.

Watanabe Y, Horie S, Funaki Y, Kikuchi Y, Yamazaki H, Ishii K, Mori S, Vassaux G, Kodama T.

J Nucl Med. 2010 Jun;51(6):951-8. doi: 10.2967/jnumed.109.074443. Epub 2010 May 19.

27.

The biology of the sodium iodide symporter and its potential for targeted gene delivery.

Hingorani M, Spitzweg C, Vassaux G, Newbold K, Melcher A, Pandha H, Vile R, Harrington K.

Curr Cancer Drug Targets. 2010 Mar;10(2):242-67. Review.

28.

Assessment of the Na/I symporter as a reporter gene to visualize oncolytic adenovirus propagation in peritoneal tumours.

Merron A, Baril P, Martin-Duque P, de la Vieja A, Tran L, Briat A, Harrington KJ, McNeish IA, Vassaux G.

Eur J Nucl Med Mol Imaging. 2010 Jul;37(7):1377-85. doi: 10.1007/s00259-009-1379-3. Epub 2010 Feb 6.

PMID:
20140612
29.

Targeted radionuclide therapy using a Wnt-targeted replicating adenovirus encoding the Na/I symporter.

Peerlinck I, Merron A, Baril P, Conchon S, Martin-Duque P, Hindorf C, Burnet J, Quintanilla M, Hingorani M, Iggo R, Lemoine NR, Harrington K, Vassaux G.

Clin Cancer Res. 2009 Nov 1;15(21):6595-601. doi: 10.1158/1078-0432.CCR-09-0262. Epub 2009 Oct 27.

30.

Visualization of gene expression in the live subject using the Na/I symporter as a reporter gene: applications in biotherapy.

Baril P, Martin-Duque P, Vassaux G.

Br J Pharmacol. 2010 Feb;159(4):761-71. doi: 10.1111/j.1476-5381.2009.00412.x. Epub 2009 Oct 8. Review.

31.

Development of an Escherichia coli expressing listeriolysin-O vaccine against Wilms tumor gene 1-expressing tumors.

Dai MS, Nitcheu-Tefit J, Alcock S, Ramirez-Jimenez F, Chao TY, Baril P, Rocha M, Brett SJ, Stauss HJ, Vassaux G.

J Immunother. 2009 Oct;32(8):845-55. doi: 10.1097/CJI.0b013e3181aee259.

PMID:
19752749
32.

In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery.

Coughlan L, Vallath S, Saha A, Flak M, McNeish IA, Vassaux G, Marshall JF, Hart IR, Thomas GJ.

J Virol. 2009 Jul;83(13):6416-28. doi: 10.1128/JVI.00445-09. Epub 2009 Apr 15.

33.

Cancer-specific transgene expression mediated by systemic injection of nanoparticles.

Chisholm EJ, Vassaux G, Martin-Duque P, Chevre R, Lambert O, Pitard B, Merron A, Weeks M, Burnet J, Peerlinck I, Dai MS, Alusi G, Mather SJ, Bolton K, Uchegbu IF, Schatzlein AG, Baril P.

Cancer Res. 2009 Mar 15;69(6):2655-62. doi: 10.1158/0008-5472.CAN-08-2657. Epub 2009 Mar 3.

34.

Inhibition of repair of radiation-induced DNA damage enhances gene expression from replication-defective adenoviral vectors.

Hingorani M, White CL, Merron A, Peerlinck I, Gore ME, Slade A, Scott SD, Nutting CM, Pandha HS, Melcher AA, Vile RG, Vassaux G, Harrington KJ.

Cancer Res. 2008 Dec 1;68(23):9771-8. doi: 10.1158/0008-5472.CAN-08-1911.

35.

Low-intensity ultrasound and microbubbles enhance the antitumor effect of cisplatin.

Watanabe Y, Aoi A, Horie S, Tomita N, Mori S, Morikawa H, Matsumura Y, Vassaux G, Kodama T.

Cancer Sci. 2008 Dec;99(12):2525-31. doi: 10.1111/j.1349-7006.2008.00989.x. Epub 2008 Nov 17.

36.

Therapeutic potential of replication-selective oncolytic adenoviruses on cells from familial and sporadic desmoid tumors.

Peerlinck I, Amini-Nik S, Phillips RK, Iggo R, Lemoine NR, Tejpar S, Vassaux G.

Clin Cancer Res. 2008 Oct 1;14(19):6187-92. doi: 10.1158/1078-0432.CCR-08-0410.

37.

Exploiting synergies between radiation and oncolytic viruses.

Harrington KJ, Melcher A, Vassaux G, Pandha HS, Vile RG.

Curr Opin Mol Ther. 2008 Aug;10(4):362-70. Review.

PMID:
18683101
38.

Radiation-mediated up-regulation of gene expression from replication-defective adenoviral vectors: implications for sodium iodide symporter gene therapy.

Hingorani M, White CL, Zaidi S, Merron A, Peerlinck I, Gore ME, Nutting CM, Pandha HS, Melcher AA, Vile RG, Vassaux G, Harrington KJ.

Clin Cancer Res. 2008 Aug 1;14(15):4915-24. doi: 10.1158/1078-0432.CCR-07-4049.

39.

Targeting sodium/iodide symporter gene expression for estrogen-regulated imaging and therapy in breast cancer.

Montiel-Equihua CA, Martín-Duque P, de la Vieja A, Quintanilla M, Burnet J, Vassaux G, Lemoine NR.

Cancer Gene Ther. 2008 Jul;15(7):465-73. doi: 10.1038/cgt.2008.6. Epub 2008 Apr 18.

PMID:
18421306
40.

A new transgenic mouse line to image chemically induced p53 activation in vivo.

Briat A, Vassaux G.

Cancer Sci. 2008 Apr;99(4):683-8. doi: 10.1111/j.1349-7006.2008.00742.x.

41.

Uveal vs. cutaneous melanoma. Origins and causes of the differences.

Belmar-Lopez C, Mancheno-Corvo P, Saornil MA, Baril P, Vassaux G, Quintanilla M, Martin-Duque P.

Clin Transl Oncol. 2008 Mar;10(3):137-42. Review.

42.

Herpes simplex virus thymidine kinase-mediated suicide gene therapy using nano/microbubbles and ultrasound.

Aoi A, Watanabe Y, Mori S, Takahashi M, Vassaux G, Kodama T.

Ultrasound Med Biol. 2008 Mar;34(3):425-34. Epub 2007 Dec 21.

PMID:
18096302
43.

Gene therapy in head and neck cancer: a review.

Chisholm E, Bapat U, Chisholm C, Alusi G, Vassaux G.

Postgrad Med J. 2007 Dec;83(986):731-7. Review.

44.

Non-invasive genetic imaging for molecular and cell therapies of cancer.

Belmar C, So PW, Vassaux G, Moleiro-Sanemeterio V, Martín-Duque P.

Clin Transl Oncol. 2007 Nov;9(11):703-14. Review.

PMID:
18055325
45.

SPECT/CT imaging of oncolytic adenovirus propagation in tumours in vivo using the Na/I symporter as a reporter gene.

Merron A, Peerlinck I, Martin-Duque P, Burnet J, Quintanilla M, Mather S, Hingorani M, Harrington K, Iggo R, Vassaux G.

Gene Ther. 2007 Dec;14(24):1731-8. Epub 2007 Oct 25.

PMID:
17960161
46.

Listeriolysin O expressed in a bacterial vaccine suppresses CD4+CD25high regulatory T cell function in vivo.

Nitcheu-Tefit J, Dai MS, Critchley-Thorne RJ, Ramirez-Jimenez F, Xu M, Conchon S, Ferry N, Stauss HJ, Vassaux G.

J Immunol. 2007 Aug 1;179(3):1532-41.

47.

Modulation of telomerase promoter tumor selectivity in the context of oncolytic adenoviruses.

Bilsland AE, Merron A, Vassaux G, Keith WN.

Cancer Res. 2007 Feb 1;67(3):1299-307.

48.

A non-invasive tissue-specific molecular delivery method of cancer gene therapy.

Kodama T, Aoi A, Vassaux G, Mori S, Morikawa H, Koshiyama KC, Yano T, Fujikawa S, Tomita Y.

Minim Invasive Ther Allied Technol. 2006;15(4):226-9.

PMID:
16966136
49.

Assessment of endostatin gene therapy for familial adenomatous polyposis-related desmoid tumors.

Martinico SC, Jezzard S, Sturt NJ, Michils G, Tejpar S, Phillips RK, Vassaux G.

Cancer Res. 2006 Aug 15;66(16):8233-40.

50.

Preclinical applications of imaging for cancer gene therapy.

Briat A, Vassaux G.

Expert Rev Mol Med. 2006 Jul 14;8(16):1-19. Review.

PMID:
16842637

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