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Items: 1 to 50 of 58

1.

Apical-Basal Polarity Signaling Components, Lgl1 and aPKCs, Control Glutamatergic Synapse Number and Function.

Scott J, Thakar S, Mao Y, Qin H, Hejran H, Lee SY, Yu T, Klezovitch O, Cheng H, Mu Y, Ghosh S, Vasioukhin V, Zou Y.

iScience. 2019 Oct 25;20:25-41. doi: 10.1016/j.isci.2019.09.005. Epub 2019 Sep 9.

2.

Recent advances in prostate cancer research: large-scale genomic analyses reveal novel driver mutations and DNA repair defects.

Frank S, Nelson P, Vasioukhin V.

F1000Res. 2018 Aug 2;7. pii: F1000 Faculty Rev-1173. doi: 10.12688/f1000research.14499.1. eCollection 2018. Review.

3.

Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration of hematopoietic stem cells.

Dash BP, Schnöder TM, Kathner C, Mohr J, Weinert S, Herzog C, Godavarthy PS, Zanetti C, Perner F, Braun-Dullaeus R, Hartleben B, Huber TB, Walz G, Naumann M, Ellis S, Vasioukhin V, Kähne T, Krause DS, Heidel FH.

J Cancer Res Clin Oncol. 2018 Oct;144(10):1933-1944. doi: 10.1007/s00432-018-2724-3. Epub 2018 Aug 6.

PMID:
30083817
4.

Erratum: ETS Related Gene mediated Androgen Receptor Aggregation and Endoplasmic Reticulum Stress in Prostate Cancer Development.

Sreenath TL, Macalindong SS, Mikhalkevich N, Sharad S, Mohamed A, Young D, Borbiev T, Xavier C, Gupta R, Jamal M, Babcock K, Tan SH, Nevalainen MT, Dobi A, Petrovics G, Sesterhenn IA, Rosner IL, Bieberich CJ, Nelson P, Vasioukhin V, Srivastava S.

Sci Rep. 2017 Sep 6;7(1):10693. doi: 10.1038/s41598-017-09612-4.

5.

Inhibition of ERG Activity in Patient-derived Prostate Cancer Xenografts by YK-4-279.

Winters B, Brown L, Coleman I, Nguyen H, Minas TZ, Kollath L, Vasioukhin V, Nelson P, Corey E, Üren A, Morrissey C.

Anticancer Res. 2017 Jul;37(7):3385-3396.

PMID:
28668826
6.

Llgl1 Connects Cell Polarity with Cell-Cell Adhesion in Embryonic Neural Stem Cells.

Jossin Y, Lee M, Klezovitch O, Kon E, Cossard A, Lien WH, Fernandez TE, Cooper JA, Vasioukhin V.

Dev Cell. 2017 Jun 5;41(5):481-495.e5. doi: 10.1016/j.devcel.2017.05.002. Epub 2017 May 25.

7.

Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells.

Beattie R, Postiglione MP, Burnett LE, Laukoter S, Streicher C, Pauler FM, Xiao G, Klezovitch O, Vasioukhin V, Ghashghaei TH, Hippenmeyer S.

Neuron. 2017 May 3;94(3):517-533.e3. doi: 10.1016/j.neuron.2017.04.012.

8.

ETS Related Gene mediated Androgen Receptor Aggregation and Endoplasmic Reticulum Stress in Prostate Cancer Development.

Sreenath TL, Macalindong SS, Mikhalkevich N, Sharad S, Mohamed A, Young D, Borbiev T, Xavier C, Gupta R, Jamal M, Babcock K, Tan SH, Nevalainen MT, Dobi A, Petrovics G, Sesterhenn IA, Rosner IL, Bieberich CJ, Nelson P, Vasioukhin V, Srivastava S.

Sci Rep. 2017 Apr 24;7(1):1109. doi: 10.1038/s41598-017-01187-4. Erratum in: Sci Rep. 2017 Sep 6;7(1):10693.

9.

DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2.

Kwan J, Sczaniecka A, Heidary Arash E, Nguyen L, Chen CC, Ratkovic S, Klezovitch O, Attisano L, McNeill H, Emili A, Vasioukhin V.

Genes Dev. 2016 Dec 15;30(24):2696-2709. doi: 10.1101/gad.284539.116.

10.

αE-catenin inhibits a Src-YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway.

Li P, Silvis MR, Honaker Y, Lien WH, Arron ST, Vasioukhin V.

Genes Dev. 2016 Apr 1;30(7):798-811. doi: 10.1101/gad.274951.115. Epub 2016 Mar 24.

11.

Cadherin signaling: keeping cells in touch.

Klezovitch O, Vasioukhin V.

F1000Res. 2015 Aug 12;4(F1000 Faculty Rev):550. doi: 10.12688/f1000research.6445.1. eCollection 2015. Review.

12.

ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors.

Nguyen LT, Tretiakova MS, Silvis MR, Lucas J, Klezovitch O, Coleman I, Bolouri H, Kutyavin VI, Morrissey C, True LD, Nelson PS, Vasioukhin V.

Cancer Cell. 2015 Jun 8;27(6):797-808. doi: 10.1016/j.ccell.2015.05.005.

13.

Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.

Wang SH, Celic I, Choi SY, Riccomagno M, Wang Q, Sun LO, Mitchell SP, Vasioukhin V, Huganir RL, Kolodkin AL.

J Neurosci. 2014 Sep 17;34(38):12745-61. doi: 10.1523/JNEUROSCI.1280-14.2014.

14.

Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis.

Tang X, Mahajan SS, Nguyen LT, Béliveau F, Leduc R, Simon JA, Vasioukhin V.

Oncotarget. 2014 Mar 15;5(5):1352-62.

15.

Your gut is right to turn left.

Klezovitch O, Vasioukhin V.

Dev Cell. 2013 Sep 30;26(6):553-4. doi: 10.1016/j.devcel.2013.08.018.

16.

Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis.

Nechiporuk T, Klezovitch O, Nguyen L, Vasioukhin V.

Dev Biol. 2013 May 15;377(2):375-84. doi: 10.1016/j.ydbio.2013.02.019. Epub 2013 Mar 4.

17.

The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML.

Heidel FH, Bullinger L, Arreba-Tutusaus P, Wang Z, Gaebel J, Hirt C, Niederwieser D, Lane SW, Döhner K, Vasioukhin V, Fischer T, Armstrong SA.

J Exp Med. 2013 Jan 14;210(1):15-22. doi: 10.1084/jem.20120596. Epub 2012 Dec 31.

18.

Adherens junctions and cancer.

Vasioukhin V.

Subcell Biochem. 2012;60:379-414. doi: 10.1007/978-94-007-4186-7_16. Review.

PMID:
22674080
19.

Loss of Llgl1 in retinal neuroepithelia reveals links between apical domain size, Notch activity and neurogenesis.

Clark BS, Cui S, Miesfeld JB, Klezovitch O, Vasioukhin V, Link BA.

Development. 2012 May;139(9):1599-610. doi: 10.1242/dev.078097.

20.

α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1.

Silvis MR, Kreger BT, Lien WH, Klezovitch O, Rudakova GM, Camargo FD, Lantz DM, Seykora JT, Vasioukhin V.

Sci Signal. 2011 May 24;4(174):ra33. doi: 10.1126/scisignal.2001823.

21.

Mammalian Llgl2 is necessary for proper branching morphogenesis during placental development.

Sripathy S, Lee M, Vasioukhin V.

Mol Cell Biol. 2011 Jul;31(14):2920-33. doi: 10.1128/MCB.05431-11. Epub 2011 May 23.

22.

Yap1 acts downstream of α-catenin to control epidermal proliferation.

Schlegelmilch K, Mohseni M, Kirak O, Pruszak J, Rodriguez JR, Zhou D, Kreger BT, Vasioukhin V, Avruch J, Brummelkamp TR, Camargo FD.

Cell. 2011 Mar 4;144(5):782-95. doi: 10.1016/j.cell.2011.02.031.

23.

Mechanisms of prostate cancer initiation and progression.

Knudsen BS, Vasioukhin V.

Adv Cancer Res. 2010;109:1-50. doi: 10.1016/B978-0-12-380890-5.00001-6. Review.

PMID:
21070913
24.

Ets family protein, erg expression in developing and adult mouse tissues by a highly specific monoclonal antibody.

Mohamed AA, Tan SH, Mikhalkevich N, Ponniah S, Vasioukhin V, Bieberich CJ, Sesterhenn IA, Dobi A, Srivastava S, Sreenath TL.

J Cancer. 2010 Oct 25;1:197-208.

25.

Discs large 5 is required for polarization of citron kinase in mitotic neural precursors.

Chang Y, Klezovitch O, Walikonis RS, Vasioukhin V, LoTurco JJ.

Cell Cycle. 2010 May 15;9(10):1990-7. Epub 2010 May 15.

26.

Adhesive and signaling functions of cadherins and catenins in vertebrate development.

Stepniak E, Radice GL, Vasioukhin V.

Cold Spring Harb Perspect Biol. 2009 Nov;1(5):a002949. doi: 10.1101/cshperspect.a002949. Review.

27.

Hepsin cooperates with MYC in the progression of adenocarcinoma in a prostate cancer mouse model.

Nandana S, Ellwood-Yen K, Sawyers C, Wills M, Weidow B, Case T, Vasioukhin V, Matusik R.

Prostate. 2010 May 1;70(6):591-600. doi: 10.1002/pros.21093.

28.

Alpha-E-catenin binds to dynamitin and regulates dynactin-mediated intracellular traffic.

Lien WH, Gelfand VI, Vasioukhin V.

J Cell Biol. 2008 Dec 15;183(6):989-97. doi: 10.1083/jcb.200805041.

29.

Identification and characterization of small-molecule inhibitors of hepsin.

Chevillet JR, Park GJ, Bedalov A, Simon JA, Vasioukhin VI.

Mol Cancer Ther. 2008 Oct;7(10):3343-51. doi: 10.1158/1535-7163.MCT-08-0446.

30.

Dissecting the role of cadherin-catenin proteins in mammalian epidermis.

Lien WH, Stepniak E, Vasioukhin V.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15225-6. doi: 10.1073/pnas.0808458105. Epub 2008 Oct 1. No abstract available.

31.

alphaE-catenin is not a significant regulator of beta-catenin signaling in the developing mammalian brain.

Lien WH, Klezovitch O, Null M, Vasioukhin V.

J Cell Sci. 2008 May 1;121(Pt 9):1357-62. doi: 10.1242/jcs.020537. Epub 2008 Apr 8.

32.

Cell polarity and cancer--cell and tissue polarity as a non-canonical tumor suppressor.

Lee M, Vasioukhin V.

J Cell Sci. 2008 Apr 15;121(Pt 8):1141-50. doi: 10.1242/jcs.016634.

33.

A causal role for ERG in neoplastic transformation of prostate epithelium.

Klezovitch O, Risk M, Coleman I, Lucas JM, Null M, True LD, Nelson PS, Vasioukhin V.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2105-10. doi: 10.1073/pnas.0711711105. Epub 2008 Feb 1.

34.

Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice.

Nechiporuk T, Fernandez TE, Vasioukhin V.

Dev Cell. 2007 Sep;13(3):338-50.

35.

Cadherin-catenin proteins in vertebrate development.

Lien WH, Klezovitch O, Vasioukhin V.

Curr Opin Cell Biol. 2006 Oct;18(5):499-506. Epub 2006 Jul 21. Review.

PMID:
16859905
36.

Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine.

Haegebarth A, Bie W, Yang R, Crawford SE, Vasioukhin V, Fuchs E, Tyner AL.

Mol Cell Biol. 2006 Jul;26(13):4949-57.

37.

alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway.

Lien WH, Klezovitch O, Fernandez TE, Delrow J, Vasioukhin V.

Science. 2006 Mar 17;311(5767):1609-12.

38.

Lethal giant puzzle of Lgl.

Vasioukhin V.

Dev Neurosci. 2006;28(1-2):13-24. Review.

PMID:
16508300
39.
40.

Hepsin paradox reveals unexpected complexity of metastatic process.

Vasioukhin V.

Cell Cycle. 2004 Nov;3(11):1394-7. Epub 2004 Nov 28.

PMID:
15539945
41.

Hepsin promotes prostate cancer progression and metastasis.

Klezovitch O, Chevillet J, Mirosevich J, Roberts RL, Matusik RJ, Vasioukhin V.

Cancer Cell. 2004 Aug;6(2):185-95.

PMID:
15324701
42.

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice.

Klezovitch O, Fernandez TE, Tapscott SJ, Vasioukhin V.

Genes Dev. 2004 Mar 1;18(5):559-71.

43.

Biogenesis and function of mouse mammary epithelium depends on the presence of functional alpha-catenin.

Nemade RV, Bierie B, Nozawa M, Bry C, Smith GH, Vasioukhin V, Fuchs E, Hennighausen L.

Mech Dev. 2004 Jan;121(1):91-9.

45.

Desmoplakin is essential in epidermal sheet formation.

Vasioukhin V, Bowers E, Bauer C, Degenstein L, Fuchs E.

Nat Cell Biol. 2001 Dec;3(12):1076-85.

PMID:
11781569
46.

Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin.

Vasioukhin V, Bauer C, Degenstein L, Wise B, Fuchs E.

Cell. 2001 Feb 23;104(4):605-17.

47.

Actin dynamics and cell-cell adhesion in epithelia.

Vasioukhin V, Fuchs E.

Curr Opin Cell Biol. 2001 Feb;13(1):76-84. Review.

PMID:
11163137
48.

Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability.

Derry JJ, Richard S, Valderrama Carvajal H, Ye X, Vasioukhin V, Cochrane AW, Chen T, Tyner AL.

Mol Cell Biol. 2000 Aug;20(16):6114-26.

49.

The origin and mechanism of circulating DNA.

Stroun M, Maurice P, Vasioukhin V, Lyautey J, Lederrey C, Lefort F, Rossier A, Chen XQ, Anker P.

Ann N Y Acad Sci. 2000 Apr;906:161-8. No abstract available.

PMID:
10818614
50.

Plasma DNA K-ras mutations in patients with gastrointestinal malignancies.

Mulcahy HE, Lyautey J, Lederrey C, Chen XQ, Lefort F, Vasioukhin V, Anker P, Alstead EM, Farthing MJ, Stroun M.

Ann N Y Acad Sci. 2000 Apr;906:25-8. No abstract available.

PMID:
10818591

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