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Sustained release of targeted cardiac therapy with a replenishable implanted epicardial reservoir.

Whyte W, Roche ET, Varela CE, Mendez K, Islam S, O'Neill H, Weafer F, Shirazi RN, Weaver JC, Vasilyev NV, McHugh PE, Murphy B, Duffy GP, Walsh CJ, Mooney DJ.

Nat Biomed Eng. 2018 Jun;2(6):416-428. doi: 10.1038/s41551-018-0247-5. Epub 2018 Jun 11.


Temporal enhancement of 2D color Doppler echocardiography sequences by fragment-based frame reordering and refinement.

Terentjev AB, Perrin DP, Settlemier SH, Zurakowski D, Smirnov PO, Del Nido PJ, Shturts IV, Vasilyev NV.

Int J Comput Assist Radiol Surg. 2019 Apr;14(4):577-586. doi: 10.1007/s11548-019-01926-0. Epub 2019 Feb 23.


An intraoperative test device for aortic valve repair.

Berra IG, Hammer PE, Berra S, Irusta AO, Chang Ryu S, Perrin DP, Vasilyev NV, Cornelis CJ, Delucis PG, Del Nido PJ.

J Thorac Cardiovasc Surg. 2019 Jan;157(1):126-132. doi: 10.1016/j.jtcvs.2018.07.113. Epub 2018 Oct 24.


Antibody-modified conduits for highly selective cytokine elimination from blood.

McAlvin JB, Wylie RG, Ramchander K, Nguyen MT, Lok CK, Moroi M, Shomorony A, Vasilyev NV, Armstrong P, Yang J, Lieber AM, Okonkwo OS, Karnik R, Kohane DS.

JCI Insight. 2018 Jul 12;3(13). pii: 121133. doi: 10.1172/jci.insight.121133.


Towards Alternative Approaches for Coupling of a Soft Robotic Sleeve to the Heart.

Horvath MA, Varela CE, Dolan EB, Whyte W, Monahan DS, Payne CJ, Wamala IA, Vasilyev NV, Pigula FA, Mooney DJ, Walsh CJ, Duffy GP, Roche ET.

Ann Biomed Eng. 2018 Oct;46(10):1534-1547. doi: 10.1007/s10439-018-2046-2. Epub 2018 May 15.


Efficient workflow for automatic segmentation of the right heart based on 2D echocardiography.

Danilov VV, Skirnevskiy IP, Gerget OM, Shelomentcev EE, Kolpashchikov DY, Vasilyev NV.

Int J Cardiovasc Imaging. 2018 Jul;34(7):1041-1055. doi: 10.1007/s10554-018-1314-4. Epub 2018 Feb 10.


A leaflet plication clip is an effective surgical template for mitral valve foldoplasty.

Wamala I, Saeed M, Ghelani SJ, Gauvreau K, Hammer PE, Vasilyev NV, Del Nido PJ.

Eur J Cardiothorac Surg. 2018 May 1;53(5):939-944. doi: 10.1093/ejcts/ezx423.


An Implantable Extracardiac Soft Robotic Device for the Failing Heart: Mechanical Coupling and Synchronization.

Payne CJ, Wamala I, Abah C, Thalhofer T, Saeed M, Bautista-Salinas D, Horvath MA, Vasilyev NV, Roche ET, Pigula FA, Walsh CJ.

Soft Robot. 2017 Sep;4(3):241-250. doi: 10.1089/soro.2016.0076. Epub 2017 May 30.


Tough adhesives for diverse wet surfaces.

Li J, Celiz AD, Yang J, Yang Q, Wamala I, Whyte W, Seo BR, Vasilyev NV, Vlassak JJ, Suo Z, Mooney DJ.

Science. 2017 Jul 28;357(6349):378-381. doi: 10.1126/science.aah6362.


An Intracardiac Soft Robotic Device for Augmentation of Blood Ejection from the Failing Right Ventricle.

Horvath MA, Wamala I, Rytkin E, Doyle E, Payne CJ, Thalhofer T, Berra I, Solovyeva A, Saeed M, Hendren S, Roche ET, Del Nido PJ, Walsh CJ, Vasilyev NV.

Ann Biomed Eng. 2017 Sep;45(9):2222-2233. doi: 10.1007/s10439-017-1855-z. Epub 2017 May 16.


Soft robotic sleeve supports heart function.

Roche ET, Horvath MA, Wamala I, Alazmani A, Song SE, Whyte W, Machaidze Z, Payne CJ, Weaver JC, Fishbein G, Kuebler J, Vasilyev NV, Mooney DJ, Pigula FA, Walsh CJ.

Sci Transl Med. 2017 Jan 18;9(373). pii: eaaf3925. doi: 10.1126/scitranslmed.aaf3925.


A Growth-Accommodating Implant for Paediatric Applications.

Feins EN, Lee Y, O'Cearbhaill ED, Vasilyev NV, Shimada S, Friehs I, Perrin D, Hammer PE, Yamauchi H, Marx G, Gosline A, Arabagi V, Karp JM, Del Nido PJ.

Nat Biomed Eng. 2017;1:818-825. doi: 10.1038/s41551-017-0142-5. Epub 2017 Oct 10.


Management of Systemic Right Ventricular Failure in Patients With Congenitally Corrected Transposition of the Great Arteries.

Filippov AA, Del Nido PJ, Vasilyev NV.

Circulation. 2016 Oct 25;134(17):1293-1302. Review.


Cardioscopic Tool-delivery Instrument for Beating-heart Surgery.

Ataollahi A, Berra I, Vasilyev NV, Machaidze Z, Dupont PE.

IEEE ASME Trans Mechatron. 2016 Feb;21(1):584-590. Epub 2015 Oct 26.


A light-reflecting balloon catheter for atraumatic tissue defect repair.

Roche ET, Fabozzo A, Lee Y, Polygerinos P, Friehs I, Schuster L, Whyte W, Casar Berazaluce AM, Bueno A, Lang N, Pereira MJ, Feins E, Wasserman S, O'Cearbhaill ED, Vasilyev NV, Mooney DJ, Karp JM, Del Nido PJ, Walsh CJ.

Sci Transl Med. 2015 Sep 23;7(306):306ra149. doi: 10.1126/scitranslmed.aaa2406. Epub 2015 Sep 23.


Concentric Tube Robot Design and Optimization Based on Task and Anatomical Constraints.

Bergeles C, Gosline AH, Vasilyev NV, Codd PJ, Del Nido PJ, Dupont PE.

IEEE Trans Robot. 2015 Feb 3;31(1):67-84.


Comparison of biomaterial delivery vehicles for improving acute retention of stem cells in the infarcted heart.

Roche ET, Hastings CL, Lewin SA, Shvartsman D, Brudno Y, Vasilyev NV, O'Brien FJ, Walsh CJ, Duffy GP, Mooney DJ.

Biomaterials. 2014 Aug;35(25):6850-6858. doi: 10.1016/j.biomaterials.2014.04.114. Epub 2014 May 23.


A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects.

Lang N, Pereira MJ, Lee Y, Friehs I, Vasilyev NV, Feins EN, Ablasser K, O'Cearbhaill ED, Xu C, Fabozzo A, Padera R, Wasserman S, Freudenthal F, Ferreira LS, Langer R, Karp JM, del Nido PJ.

Sci Transl Med. 2014 Jan 8;6(218):218ra6. doi: 10.1126/scitranslmed.3006557.


A bioinspired soft actuated material.

Roche ET, Wohlfarth R, Overvelde JT, Vasilyev NV, Pigula FA, Mooney DJ, Bertoldi K, Walsh CJ.

Adv Mater. 2014 Feb 26;26(8):1200-6. doi: 10.1002/adma.201304018. Epub 2013 Nov 8.


Repair of posterior mitral valve prolapse with a novel leaflet plication clip in an animal model.

Feins EN, Yamauchi H, Marx GR, Freudenthal FP, Liu H, Del Nido PJ, Vasilyev NV.

J Thorac Cardiovasc Surg. 2014 Feb;147(2):783-90; discussion 790-1. doi: 10.1016/j.jtcvs.2013.09.044. Epub 2013 Nov 8.


Creation of nonischemic functional mitral regurgitation by annular dilatation and nonplanar modification in a chronic in vivo swine model.

Yamauchi H, Feins EN, Vasilyev NV, Shimada S, Zurakowski D, Del Nido PJ.

Circulation. 2013 Sep 10;128(11 Suppl 1):S263-70. doi: 10.1161/CIRCULATIONAHA.112.000396.


Percutaneous steerable robotic tool delivery platform and metal microelectromechanical systems device for tissue manipulation and approximation: closure of patent foramen ovale in an animal model.

Vasilyev NV, Gosline AH, Butler E, Lang N, Codd PJ, Yamauchi H, Feins EN, Folk CR, Cohen AL, Chen R, Zurakowski D, del Nido PJ, Dupont PE.

Circ Cardiovasc Interv. 2013 Aug;6(4):468-75. doi: 10.1161/CIRCINTERVENTIONS.112.000324. Epub 2013 Jul 30.


Percutaneous intracardiac beating-heart surgery using metal MEMS tissue approximation tools.

Gosline AH, Vasilyev NV, Butler EJ, Folk C, Cohen A, Chen R, Lang N, Del Nido PJ, Dupont PE.

Int J Rob Res. 2012 Aug 1;31(9):1081-1093.


Enabling 3D Ultrasound Procedure Guidance through Enhanced Visualization.

Brattain LJ, Vasilyev NV, Howe RD.

Inf Process Comput Assist Interv (2012). 2012 Jun;7330:115-124. doi: 10.1007/978-3-642-30618-1_12.


Temporal enhancement of 3D echocardiography by frame reordering.

Perrin DP, Vasilyev NV, Marx GR, del Nido PJ.

JACC Cardiovasc Imaging. 2012 Mar;5(3):300-4. doi: 10.1016/j.jcmg.2011.10.006.


Robotics and imaging in congenital heart surgery.

Vasilyev NV, Dupont PE, del Nido PJ.

Future Cardiol. 2012 Mar;8(2):285-96. doi: 10.2217/fca.12.20. Review.


Right ventricular papillary muscle approximation as a novel technique of valve repair for functional tricuspid regurgitation in an ex vivo porcine model.

Yamauchi H, Vasilyev NV, Marx GR, Loyola H, Padala M, Yoganathan AP, del Nido PJ.

J Thorac Cardiovasc Surg. 2012 Jul;144(1):235-42. doi: 10.1016/j.jtcvs.2012.01.028. Epub 2012 Feb 16.


In vitro characterization of bicuspid aortic valve hemodynamics using particle image velocimetry.

Saikrishnan N, Yap CH, Milligan NC, Vasilyev NV, Yoganathan AP.

Ann Biomed Eng. 2012 Aug;40(8):1760-75. doi: 10.1007/s10439-012-0527-2. Epub 2012 Feb 9. Erratum in: Ann Biomed Eng. 2012 Aug;40(8):1776.


Detection of Curved Robots using 3D Ultrasound.

Ren H, Vasilyev NV, Dupont PE.

Rep U S. 2011 Sep 25;2011:2083-2089.


Metal MEMS Tools for Beating-heart Tissue Approximation.

Butler EJ, Folk C, Cohen A, Vasilyev NV, Chen R, Del Nido PJ, Dupont PE.

IEEE Int Conf Robot Autom. 2011 May 9;2011:411-416.


Metal MEMS Tools for Beating-heart Tissue Removal.

Gosline AH, Vasilyev NV, Veeramani A, Wu M, Schmitz G, Chen R, Arabagi V, Del Nido PJ, Dupont PE.

IEEE Int Conf Robot Autom. 2012. doi: 10.1109/ICRA.2012.6225210.


On the Design of an Interactive, Patient-Specific Surgical Simulator for Mitral Valve Repair.

Tenenholtz NA, Hammer PE, Schneider RJ, Vasilyev NV, Howe RD.

Rep U S. 2011 Dec 31;2011:1327-1332.


Mitral annulus segmentation from four-dimensional ultrasound using a valve state predictor and constrained optical flow.

Schneider RJ, Perrin DP, Vasilyev NV, Marx GR, del Nido PJ, Howe RD.

Med Image Anal. 2012 Feb;16(2):497-504. doi: 10.1016/ Epub 2011 Dec 4.


Real-time image-based rigid registration of three-dimensional ultrasound.

Schneider RJ, Perrin DP, Vasilyev NV, Marx GR, Del Nido PJ, Howe RD.

Med Image Anal. 2012 Feb;16(2):402-14. doi: 10.1016/ Epub 2011 Nov 15.


A novel cardioport for beating-heart, image-guided intracardiac surgery.

Vasilyev NV, Kawata M, DiBiasio CM, Durand KV, Hopkins J, Traina ZJ, Slocum AH, del Nido PJ.

J Thorac Cardiovasc Surg. 2011 Dec;142(6):1545-51. doi: 10.1016/j.jtcvs.2011.07.041. Epub 2011 Sep 8.


Creation of a tricuspid valve regurgitation model from tricuspid annular dilatation using the cardioport video-assisted imaging system.

Walter EM, Vasilyev NV, Sill B, Padala M, Jimenez J, Yoganathan AP, Hetzer R, del Nido PJ.

J Heart Valve Dis. 2011 Mar;20(2):184-8. Erratum in: J Heart Valve Dis. 2011 May;20(3):281. Delmo Walter, Eva Maria [corrected to Walter, Eva Maria Delmo].


Force Tracking with Feed-Forward Motion Estimation for Beating Heart Surgery.

Yuen SG, Perrin DP, Vasilyev NV, Del Nido PJ, Howe RD.

IEEE Trans Robot. 2010 Aug 16;26(5):888-896. doi: 10.1109/TRO.2010.2053734.


Robotic tissue tracking for beating heart mitral valve surgery.

Yuen SG, Vasilyev NV, del Nido PJ, Howe RD.

Med Image Anal. 2013 Dec;17(8):1236-42. doi: 10.1016/ Epub 2010 Jul 6.


Mitral annulus segmentation from 3D ultrasound using graph cuts.

Schneider RJ, Perrin DP, Vasilyev NV, Marx GR, del Nido PJ, Howe RD.

IEEE Trans Med Imaging. 2010 Sep;29(9):1676-87. doi: 10.1109/TMI.2010.2050595. Epub 2010 Jun 17.


Robotic Force Stabilization for Beating Heart Intracardiac Surgery.

Yuen SG, Yip MC, Vasilyev NV, Perrin DP, Del Nido PJ, Howe RD.

Med Image Comput Comput Assist Interv. 2009 Oct 1;5761(2009):26-33.


Beating-heart mitral valve suture annuloplasty under real-time three-dimensional echocardiography guidance: an ex vivo study.

Kawata M, Vasilyev NV, Perrin DP, del Nido PJ.

Interact Cardiovasc Thorac Surg. 2010 Jul;11(1):6-9. doi: 10.1510/icvts.2010.233320. Epub 2010 Apr 15.


Image guided surgical interventions.

Perrin DP, Vasilyev NV, Novotny P, Stoll J, Howe RD, Dupont PE, Salgo IS, del Nido PJ.

Curr Probl Surg. 2009 Sep;46(9):730-66. doi: 10.1067/j.cpsurg.2009.04.001. Review. No abstract available.


In brief.

Perrin DP, Vasilyev NV, Novotny P, Stoll J, Howe RD, Dupont PE, Salgo IS, Del Nido PJ.

Curr Probl Surg. 2009 Sep;46(9):723-7. No abstract available.


Evaluation of a new hybrid technique for closure of muscular ventricular septal defects in a long-term setting.

Kozlik-Feldmann R, Lang N, Lehner A, Sigler M, Schmitz C, Sodian R, Freudenthal F, Dalla-Pozza R, Vasilyev NV, del Nido PJ, Netz H.

J Thorac Cardiovasc Surg. 2009 Aug;138(2):365-73. doi: 10.1016/j.jtcvs.2009.02.014. Epub 2009 Apr 29.


Mitral Annulus Segmentation from Three-Dimensional Ultrasound.

Schneider RJ, Perrin DP, Vasilyev NV, Marx GR, Del Nido PJ, Howe RD.

Proc IEEE Int Symp Biomed Imaging. 2009:779-782.


Robotic force stabilization for beating heart intracardiac surgery.

Yuen SG, Yip MC, Vasilyev NV, Perrin DP, del Nido PJ, Howe RD.

Med Image Comput Comput Assist Interv. 2009;12(Pt 1):26-33.


Cleft closure and undersizing annuloplasty improve mitral repair in atrioventricular canal defects.

Padala M, Vasilyev NV, Owen JW Jr, Jimenez JH, Dasi LP, del Nido PJ, Yoganathan AP.

J Thorac Cardiovasc Surg. 2008 Nov;136(5):1243-9. doi: 10.1016/j.jtcvs.2008.05.043. Epub 2008 Sep 14.


3D ultrasound-guided motion compensation system for beating heart mitral valve repair.

Yuen SG, Kesner SB, Vasilyev NV, Del Nido PJ, Howe RD.

Med Image Comput Comput Assist Interv. 2008;11(Pt 1):711-9.


Stereoscopic vision display technology in real-time three-dimensional echocardiography-guided intracardiac beating-heart surgery.

Vasilyev NV, Novotny PM, Martinez JF, Loyola H, Salgo IS, Howe RD, del Nido PJ.

J Thorac Cardiovasc Surg. 2008 Jun;135(6):1334-41. doi: 10.1016/j.jtcvs.2007.12.045. Epub 2008 May 2.


Patch closure of muscular ventricular septal defects with a new hybrid therapy in a pig model.

Kozlik-Feldmann R, Lang N, Aumann R, Lehner A, Rassoulian D, Sodian R, Schmitz C, Hinterseer M, Hinkel R, Thein E, Freudenthal F, Vasilyev NV, del Nido PJ, Netz H.

J Am Coll Cardiol. 2008 Apr 22;51(16):1597-603. doi: 10.1016/j.jacc.2007.10.068. Erratum in: J Am Coll Cardiol. 2008 Jun 3;51(22): 2197. Vasylev, Nikolay V [corrected to Vasilyev, Nikolay V].

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