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Items: 1 to 50 of 211

1.

Genetics and functions of the retinoic acid pathway, with special emphasis on the eye.

Thompson B, Katsanis N, Apostolopoulos N, Thompson DC, Nebert DW, Vasiliou V.

Hum Genomics. 2019 Dec 3;13(1):61. doi: 10.1186/s40246-019-0248-9. Review.

2.

Molecular Pathway Analysis Indicates a Distinct Metabolic Phenotype in Women With Right-Sided Colon Cancer.

Sun Y, Mironova V, Chen Y, Lundh EPF, Zhang Q, Cai Y, Vasiliou V, Zhang Y, Garcia-Milian R, Khan SA, Johnson CH.

Transl Oncol. 2019 Nov 21;13(1):42-56. doi: 10.1016/j.tranon.2019.09.004. [Epub ahead of print]

3.

Prevalence and significance of race and ethnicity subgroup analyses in Cochrane intervention reviews.

Liu P, Ross JS, Ioannidis JP, Dhruva SS, Vasiliou V, Wallach JD.

Clin Trials. 2019 Nov 10:1740774519887148. doi: 10.1177/1740774519887148. [Epub ahead of print] No abstract available.

PMID:
31709809
4.

Age-treatment subgroup analyses in Cochrane intervention reviews: a meta-epidemiological study.

Liu P, Ioannidis JPA, Ross JS, Dhruva SS, Luxkaranayagam AT, Vasiliou V, Wallach JD.

BMC Med. 2019 Oct 21;17(1):188. doi: 10.1186/s12916-019-1420-8.

5.

Glutathione deficiency-elicited reprogramming of hepatic metabolism protects against alcohol-induced steatosis.

Chen Y, Manna SK, Golla S, Krausz KW, Cai Y, Garcia-Milian R, Chakraborty T, Chakraborty J, Chatterjee R, Thompson DC, Gonzalez FJ, Vasiliou V.

Free Radic Biol Med. 2019 Nov 1;143:127-139. doi: 10.1016/j.freeradbiomed.2019.07.025. Epub 2019 Jul 24.

PMID:
31351176
6.

Determining the endocrine disruption potential of industrial chemicals using an integrative approach: Public databases, in vitro exposure, and modeling receptor interactions.

Alofe O, Kisanga E, Inayat-Hussain SH, Fukumura M, Garcia-Milian R, Perera L, Vasiliou V, Whirledge S.

Environ Int. 2019 Oct;131:104969. doi: 10.1016/j.envint.2019.104969. Epub 2019 Jul 13.

7.

1,4-Dioxane as an emerging water contaminant: State of the science and evaluation of research needs.

Godri Pollitt KJ, Kim JH, Peccia J, Elimelech M, Zhang Y, Charkoftaki G, Hodges B, Zucker I, Huang H, Deziel NC, Murphy K, Ishii M, Johnson CH, Boissevain A, O'Keefe E, Anastas PT, Orlicky D, Thompson DC, Vasiliou V.

Sci Total Environ. 2019 Nov 10;690:853-866. doi: 10.1016/j.scitotenv.2019.06.443. Epub 2019 Jun 28. Review.

PMID:
31302550
8.

Psychological Inflexibility in Pain Scale: Greek adaptation, psychometric properties, and invariance testing across three pain samples.

Vasiliou VS, Michaelides MP, Kasinopoulos O, Karekla M.

Psychol Assess. 2019 Jul;31(7):895-904. doi: 10.1037/pas0000705. Epub 2019 Mar 21.

PMID:
30896210
9.

Expression, purification and crystallization of the novel Xenopus tropicalis ALDH16B1, a homologue of human ALDH16A1.

Pantouris G, Dioletis E, Chen Y, Thompson DC, Vasiliou V, Lolis EJ.

Chem Biol Interact. 2019 May 1;304:168-172. doi: 10.1016/j.cbi.2019.03.009. Epub 2019 Mar 17.

PMID:
30894314
10.

Ethanol sensitizes skeletal muscle to ammonia-induced molecular perturbations.

Kant S, Davuluri G, Alchirazi KA, Welch N, Heit C, Kumar A, Gangadhariah M, Kim A, McMullen MR, Willard B, Luse DS, Nagy LE, Vasiliou V, Marini AM, Weiner ID, Dasarathy S.

J Biol Chem. 2019 May 3;294(18):7231-7244. doi: 10.1074/jbc.RA118.005411. Epub 2019 Mar 14.

PMID:
30872403
11.

Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells.

Charkoftaki G, Thompson DC, Golla JP, Garcia-Milian R, Lam TT, Engel J, Vasiliou V.

Chem Biol Interact. 2019 May 1;304:88-96. doi: 10.1016/j.cbi.2019.02.030. Epub 2019 Mar 6. No abstract available.

PMID:
30851239
12.

Hepatic metabolic adaptation in a murine model of glutathione deficiency.

Chen Y, Golla S, Garcia-Milian R, Thompson DC, Gonzalez FJ, Vasiliou V.

Chem Biol Interact. 2019 Apr 25;303:1-6. doi: 10.1016/j.cbi.2019.02.015. Epub 2019 Feb 20.

13.

Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an "evolutionary bloom".

Charkoftaki G, Wang Y, McAndrews M, Bruford EA, Thompson DC, Vasiliou V, Nebert DW.

Hum Genomics. 2019 Feb 19;13(1):11. doi: 10.1186/s40246-019-0191-9. Review.

14.

Ethanol induces skin hyperpigmentation in mice with aldehyde dehydrogenase 2 deficiency.

Matsumoto A, Ito S, Wakamatsu K, Ichiba M, Vasiliou V, Akao C, Song BJ, Fujita M.

Chem Biol Interact. 2019 Apr 1;302:61-66. doi: 10.1016/j.cbi.2019.01.035. Epub 2019 Feb 2.

PMID:
30721697
15.

Evaluation of potential carcinogenicity of organic chemicals in synthetic turf crumb rubber.

Perkins AN, Inayat-Hussain SH, Deziel NC, Johnson CH, Ferguson SS, Garcia-Milian R, Thompson DC, Vasiliou V.

Environ Res. 2019 Feb;169:163-172. doi: 10.1016/j.envres.2018.10.018. Epub 2018 Oct 24.

16.

Engineered Animal Models Designed for Investigating Ethanol Metabolism, Toxicity and Cancer.

Marshall S, Chen Y, Singh S, Berrios-Carcamo P, Heit C, Apostolopoulos N, Golla JP, Thompson DC, Vasiliou V.

Adv Exp Med Biol. 2018;1032:203-221. doi: 10.1007/978-3-319-98788-0_14. Review.

17.

Glutathione and Transsulfuration in Alcohol-Associated Tissue Injury and Carcinogenesis.

Chen Y, Han M, Matsumoto A, Wang Y, Thompson DC, Vasiliou V.

Adv Exp Med Biol. 2018;1032:37-53. doi: 10.1007/978-3-319-98788-0_3. Review.

18.

Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation.

Lian G, Gnanaprakasam JR, Wang T, Wu R, Chen X, Liu L, Shen Y, Yang M, Yang J, Chen Y, Vasiliou V, Cassel TA, Green DR, Liu Y, Fan TW, Wang R.

Elife. 2018 Sep 10;7. pii: e36158. doi: 10.7554/eLife.36158.

19.

Prioritization of reproductive toxicants in unconventional oil and gas operations using a multi-country regulatory data-driven hazard assessment.

Inayat-Hussain SH, Fukumura M, Muiz Aziz A, Jin CM, Jin LW, Garcia-Milian R, Vasiliou V, Deziel NC.

Environ Int. 2018 Aug;117:348-358. doi: 10.1016/j.envint.2018.05.010. Epub 2018 May 21.

PMID:
29793188
20.

Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.

Yang SM, Martinez NJ, Yasgar A, Danchik C, Johansson C, Wang Y, Baljinnyam B, Wang AQ, Xu X, Shah P, Cheff D, Wang XS, Roth J, Lal-Nag M, Dunford JE, Oppermann U, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ.

J Med Chem. 2018 Jun 14;61(11):4883-4903. doi: 10.1021/acs.jmedchem.8b00270. Epub 2018 May 31.

21.

Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity.

Yasgar A, Titus SA, Wang Y, Danchik C, Yang SM, Vasiliou V, Jadhav A, Maloney DJ, Simeonov A, Martinez NJ.

PLoS One. 2018 May 15;13(5):e0197292. doi: 10.1371/journal.pone.0197292. eCollection 2018.

22.

Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level.

Charkoftaki G, Rattray NJW, Andrén PE, Caprioli RM, Castellino S, Duncan MW, Goodwin RJA, Schey KL, Shahidi-Latham SK, Veselkov KA, Johnson CH, Vasiliou V.

Hum Genomics. 2018 Feb 27;12(1):10. doi: 10.1186/s40246-018-0142-x. No abstract available.

23.

Beyond genomics: understanding exposotypes through metabolomics.

Rattray NJW, Deziel NC, Wallach JD, Khan SA, Vasiliou V, Ioannidis JPA, Johnson CH.

Hum Genomics. 2018 Jan 26;12(1):4. doi: 10.1186/s40246-018-0134-x. Review.

24.

Yale school of public health symposium on lifetime exposures and human health: the exposome; summary and future reflections.

Johnson CH, Athersuch TJ, Collman GW, Dhungana S, Grant DF, Jones DP, Patel CJ, Vasiliou V.

Hum Genomics. 2017 Dec 8;11(1):32. doi: 10.1186/s40246-017-0128-0.

25.

Nitrogen mustard-induced corneal injury involves the sphingomyelin-ceramide pathway.

Charkoftaki G, Jester JV, Thompson DC, Vasiliou V.

Ocul Surf. 2018 Jan;16(1):154-162. doi: 10.1016/j.jtos.2017.11.004. Epub 2017 Nov 10.

PMID:
29129753
26.

Aldehyde dehydrogenase 1B1: a novel immunohistological marker for colorectal cancer.

Matsumoto A, Arcaroli J, Chen Y, Gasparetto M, Neumeister V, Thompson DC, Singh S, Smith C, Messersmith W, Vasiliou V.

Br J Cancer. 2017 Nov 7;117(10):1537-1543. doi: 10.1038/bjc.2017.304. Epub 2017 Sep 7.

27.

The impact of experiential avoidance on the relations between illness representations, pain catastrophising and pain interference in chronic pain.

Karademas EC, Karekla M, Flouri M, Vasiliou VS, Kasinopoulos O, Papacostas SS.

Psychol Health. 2017 Dec;32(12):1469-1484. doi: 10.1080/08870446.2017.1346193. Epub 2017 Jul 3.

PMID:
28671480
28.

Environmental influences in the etiology of colorectal cancer: the premise of metabolomics.

Rattray NJW, Charkoftaki G, Rattray Z, Hansen JE, Vasiliou V, Johnson CH.

Curr Pharmacol Rep. 2017 Jun;3(3):114-125. doi: 10.1007/s40495-017-0088-z. Epub 2017 Apr 7.

29.

Glutathione Primes T Cell Metabolism for Inflammation.

Mak TW, Grusdat M, Duncan GS, Dostert C, Nonnenmacher Y, Cox M, Binsfeld C, Hao Z, Brüstle A, Itsumi M, Jäger C, Chen Y, Pinkenburg O, Camara B, Ollert M, Bindslev-Jensen C, Vasiliou V, Gorrini C, Lang PA, Lohoff M, Harris IS, Hiller K, Brenner D.

Immunity. 2017 Jun 20;46(6):1089-1090. doi: 10.1016/j.immuni.2017.06.009. No abstract available.

30.

Glutathione Primes T Cell Metabolism for Inflammation.

Mak TW, Grusdat M, Duncan GS, Dostert C, Nonnenmacher Y, Cox M, Binsfeld C, Hao Z, Brüstle A, Itsumi M, Jäger C, Chen Y, Pinkenburg O, Camara B, Ollert M, Bindslev-Jensen C, Vasiliou V, Gorrini C, Lang PA, Lohoff M, Harris IS, Hiller K, Brenner D.

Immunity. 2017 Apr 18;46(4):675-689. doi: 10.1016/j.immuni.2017.03.019. Erratum in: Immunity. 2017 Jun 20;46(6):1089-1090.

31.

Construct validity of the G-CPAQ and its mediating role in pain interference and adjustment.

Vasiliou VS, Karekla M, Michaelides MP, Kasinopoulos O.

Psychol Assess. 2018 Feb;30(2):220-230. doi: 10.1037/pas0000467. Epub 2017 Apr 3.

PMID:
28368172
32.

Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1.

Gasparetto M, Pei S, Minhajuddin M, Khan N, Pollyea DA, Myers JR, Ashton JM, Becker MW, Vasiliou V, Humphries KR, Jordan CT, Smith CA.

Haematologica. 2017 Jun;102(6):1054-1065. doi: 10.3324/haematol.2016.159053. Epub 2017 Mar 9.

33.

Aromatase inhibitors induced autoimmune disorders in patients with breast cancer: A review.

Zarkavelis G, Kollas A, Kampletsas E, Vasiliou V, Kaltsonoudis E, Drosos A, Khaled H, Pavlidis N.

J Adv Res. 2016 Sep;7(5):719-726. doi: 10.1016/j.jare.2016.04.001. Epub 2016 Apr 23. Review.

34.

Transcriptomic analysis and plasma metabolomics in Aldh16a1-null mice reveals a potential role of ALDH16A1 in renal function.

Charkoftaki G, Chen Y, Han M, Sandoval M, Yu X, Zhao H, Orlicky DJ, Thompson DC, Vasiliou V.

Chem Biol Interact. 2017 Oct 1;276:15-22. doi: 10.1016/j.cbi.2017.02.013. Epub 2017 Feb 28.

35.

Racemic Salsolinol and its Enantiomers Act as Agonists of the μ-Opioid Receptor by Activating the Gi Protein-Adenylate Cyclase Pathway.

Berríos-Cárcamo P, Quintanilla ME, Herrera-Marschitz M, Vasiliou V, Zapata-Torres G, Rivera-Meza M.

Front Behav Neurosci. 2017 Jan 23;10:253. doi: 10.3389/fnbeh.2016.00253. eCollection 2016.

36.

A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity.

Yasgar A, Titus SA, Wang Y, Danchik C, Yang SM, Vasiliou V, Jadhav A, Maloney DJ, Simeonov A, Martinez NJ.

PLoS One. 2017 Jan 27;12(1):e0170937. doi: 10.1371/journal.pone.0170937. eCollection 2017. Erratum in: PLoS One. 2018 May 15;13(5):e0197292.

37.

Corneal haze phenotype in Aldh3a1-null mice: In vivo confocal microscopy and tissue imaging mass spectrometry.

Chen Y, Jester JV, Anderson DM, Marchitti SA, Schey KL, Thompson DC, Vasiliou V.

Chem Biol Interact. 2017 Oct 1;276:9-14. doi: 10.1016/j.cbi.2016.12.017. Epub 2016 Dec 27.

PMID:
28038895
38.

Catalase deletion promotes prediabetic phenotype in mice.

Heit C, Marshall S, Singh S, Yu X, Charkoftaki G, Zhao H, Orlicky DJ, Fritz KS, Thompson DC, Vasiliou V.

Free Radic Biol Med. 2017 Feb;103:48-56. doi: 10.1016/j.freeradbiomed.2016.12.011. Epub 2016 Dec 8.

39.

Assessing the Learning Environment for Medical Students: An Evaluation of a Novel Survey Instrument in Four Medical Schools.

Pololi LH, Evans AT, Nickell L, Reboli AC, Coplit LD, Stuber ML, Vasiliou V, Civian JT, Brennan RT.

Acad Psychiatry. 2017 Jun;41(3):354-359. doi: 10.1007/s40596-016-0620-1. Epub 2016 Nov 10.

PMID:
27834037
40.

Roles of defective ALDH2 polymorphism on liver protection and cancer development.

Matsumoto A, Thompson DC, Chen Y, Kitagawa K, Vasiliou V.

Environ Health Prev Med. 2016 Nov;21(6):395-402. Epub 2016 Oct 6. Review.

41.

Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2.

Keysar SB, Le PN, Miller B, Jackson BC, Eagles JR, Nieto C, Kim J, Tang B, Glogowska MJ, Morton JJ, Padilla-Just N, Gomez K, Warnock E, Reisinger J, Arcaroli JJ, Messersmith WA, Wakefield LM, Gao D, Tan AC, Serracino H, Vasiliou V, Roop DR, Wang XJ, Jimeno A.

J Natl Cancer Inst. 2016 Sep 15;109(1). doi: 10.1093/jnci/djw189. Print 2017 Jan.

42.

Quantification of Neural Ethanol and Acetaldehyde Using Headspace GC-MS.

Heit C, Eriksson P, Thompson DC, Charkoftaki G, Fritz KS, Vasiliou V.

Alcohol Clin Exp Res. 2016 Sep;40(9):1825-31. doi: 10.1111/acer.13156. Epub 2016 Aug 8.

43.

Chronic Glutathione Depletion Confers Protection against Alcohol-induced Steatosis: Implication for Redox Activation of AMP-activated Protein Kinase Pathway.

Chen Y, Singh S, Matsumoto A, Manna SK, Abdelmegeed MA, Golla S, Murphy RC, Dong H, Song BJ, Gonzalez FJ, Thompson DC, Vasiliou V.

Sci Rep. 2016 Jul 12;6:29743. doi: 10.1038/srep29743.

44.

Letter to the editor for "Update of the human and mouse Fanconi anemia genes".

Nebert DW, Dong H, Bruford EA, Thompson DC, Joenje H, Vasiliou V.

Hum Genomics. 2016 Jul 4;10(1):25. doi: 10.1186/s40246-016-0081-3. No abstract available.

45.

Heme oxygenase 1 protects ethanol-administered liver tissue in Aldh2 knockout mice.

Matsumoto A, Thompson D, Chen Y, Vasiliou V, Kawamoto T, Ichiba M.

Alcohol. 2016 May;52:49-54. doi: 10.1016/j.alcohol.2016.02.004. Epub 2016 Mar 4.

PMID:
27139237
46.

ALDH3A1 Plays a Functional Role in Maintenance of Corneal Epithelial Homeostasis.

Koppaka V, Chen Y, Mehta G, Orlicky DJ, Thompson DC, Jester JV, Vasiliou V.

PLoS One. 2016 Jan 11;11(1):e0146433. doi: 10.1371/journal.pone.0146433. eCollection 2016.

47.

Update of the human and mouse Fanconi anemia genes.

Dong H, Nebert DW, Bruford EA, Thompson DC, Joenje H, Vasiliou V.

Hum Genomics. 2015 Nov 24;9:32. doi: 10.1186/s40246-015-0054-y. Review.

48.

Aldehyde Dehydrogenase 1B1 as a Modulator of Pancreatic Adenocarcinoma.

Singh S, Arcaroli JJ, Orlicky DJ, Chen Y, Messersmith WA, Bagby S, Purkey A, Quackenbush KS, Thompson DC, Vasiliou V.

Pancreas. 2016 Jan;45(1):117-22. doi: 10.1097/MPA.0000000000000542.

49.

Dead enzymes in the aldehyde dehydrogenase gene family: role in drug metabolism and toxicology.

Jackson BC, Thompson DC, Charkoftaki G, Vasiliou V.

Expert Opin Drug Metab Toxicol. 2015;11(12):1839-47. doi: 10.1517/17425255.2016.1108406. Epub 2015 Nov 11. Review.

50.

Mentoring Faculty: A US National Survey of Its Adequacy and Linkage to Culture in Academic Health Centers.

Pololi LH, Evans AT, Civian JT, Vasiliou V, Coplit LD, Gillum LH, Gibbs BK, Brennan RT.

J Contin Educ Health Prof. 2015 Summer;35(3):176-84. doi: 10.1002/chp.21294.

PMID:
26378423

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