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Items: 37


Iron-regulated expression of alginate production, mucoid phenotype, and biofilm formation by Pseudomonas aeruginosa.

Wiens JR, Vasil AI, Schurr MJ, Vasil ML.

MBio. 2014 Feb 4;5(1):e01010-13. doi: 10.1128/mBio.01010-13.


The complex interplay of iron, biofilm formation, and mucoidy affecting antimicrobial resistance of Pseudomonas aeruginosa.

Oglesby-Sherrouse AG, Djapgne L, Nguyen AT, Vasil AI, Vasil ML.

Pathog Dis. 2014 Apr;70(3):307-20. doi: 10.1111/2049-632X.12132. Epub 2014 Feb 10.


Recruitment of a phospholipase C/sphingomyelinase into non-lamellar lipid droplets during hydrolysis of lipid bilayers.

Ibarguren M, Sot J, Montes LR, Vasil AI, Vasil ML, Goñi FM, Alonso A.

Chem Phys Lipids. 2013 Jan;166:12-7. doi: 10.1016/j.chemphyslip.2012.12.001. Epub 2012 Dec 17.


Imaging the early stages of phospholipase C/sphingomyelinase activity on vesicles containing coexisting ordered-disordered and gel-fluid domains.

Ibarguren M, López DJ, Montes LR, Sot J, Vasil AI, Vasil ML, Goñi FM, Alonso A.

J Lipid Res. 2011 Apr;52(4):635-45. doi: 10.1194/jlr.M012591. Epub 2011 Jan 20.


Multiple phospholipid substrates of phospholipase C/sphingomyelinase HR2 from Pseudomonas aeruginosa.

López DJ, Collado MI, Ibarguren M, Vasil AI, Vasil ML, Goñi FM, Alonso A.

Chem Phys Lipids. 2011 Jan;164(1):78-82. doi: 10.1016/j.chemphyslip.2010.11.001. Epub 2010 Nov 10.


End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa.

Ibarguren M, Bomans PH, Frederik PM, Stonehouse M, Vasil AI, Vasil ML, Alonso A, Goñi FM.

Biochim Biophys Acta. 2010 Jan;1798(1):59-64. doi: 10.1016/j.bbamem.2009.10.017. Epub 2009 Nov 3.


A complex extracellular sphingomyelinase of Pseudomonas aeruginosa inhibits angiogenesis by selective cytotoxicity to endothelial cells.

Vasil ML, Stonehouse MJ, Vasil AI, Wadsworth SJ, Goldfine H, Bolcome RE 3rd, Chan J.

PLoS Pathog. 2009 May;5(5):e1000420. doi: 10.1371/journal.ppat.1000420. Epub 2009 May 8.


Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides.

Jiang Z, Vasil AI, Hale J, Hancock RE, Vasil ML, Hodges RS.

Adv Exp Med Biol. 2009;611:561-2. No abstract available.


Effects of hydrophobicity on the antifungal activity of alpha-helical antimicrobial peptides.

Jiang Z, Kullberg BJ, van der Lee H, Vasil AI, Hale JD, Mant CT, Hancock RE, Vasil ML, Netea MG, Hodges RS.

Chem Biol Drug Des. 2008 Dec;72(6):483-95. doi: 10.1111/j.1747-0285.2008.00728.x.


Pseudomonas aeruginosa twitching motility-mediated chemotaxis towards phospholipids and fatty acids: specificity and metabolic requirements.

Miller RM, Tomaras AP, Barker AP, Voelker DR, Chan ED, Vasil AI, Vasil ML.

J Bacteriol. 2008 Jun;190(11):4038-49. doi: 10.1128/JB.00129-08. Epub 2008 Apr 4.


Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides.

Chen Y, Guarnieri MT, Vasil AI, Vasil ML, Mant CT, Hodges RS.

Antimicrob Agents Chemother. 2007 Apr;51(4):1398-406. Epub 2006 Dec 11.


Comparison of biophysical and biologic properties of alpha-helical enantiomeric antimicrobial peptides.

Chen Y, Vasil AI, Rehaume L, Mant CT, Burns JL, Vasil ML, Hancock RE, Hodges RS.

Chem Biol Drug Des. 2006 Feb;67(2):162-73.


A novel extracellular phospholipase C of Pseudomonas aeruginosa is required for phospholipid chemotaxis.

Barker AP, Vasil AI, Filloux A, Ball G, Wilderman PJ, Vasil ML.

Mol Microbiol. 2004 Aug;53(4):1089-98.


Purification, characterization, and identification of a sphingomyelin synthase from Pseudomonas aeruginosa. PlcH is a multifunctional enzyme.

Luberto C, Stonehouse MJ, Collins EA, Marchesini N, El-Bawab S, Vasil AI, Vasil ML, Hannun YA.

J Biol Chem. 2003 Aug 29;278(35):32733-43. Epub 2003 Jun 10.


A novel class of microbial phosphocholine-specific phospholipases C.

Stonehouse MJ, Cota-Gomez A, Parker SK, Martin WE, Hankin JA, Murphy RC, Chen W, Lim KB, Hackett M, Vasil AI, Vasil ML.

Mol Microbiol. 2002 Nov;46(3):661-76.


Pseudomonas aeruginosa synthesizes phosphatidylcholine by use of the phosphatidylcholine synthase pathway.

Wilderman PJ, Vasil AI, Martin WE, Murphy RC, Vasil ML.

J Bacteriol. 2002 Sep;184(17):4792-9.


Effects of the twin-arginine translocase on secretion of virulence factors, stress response, and pathogenesis.

Ochsner UA, Snyder A, Vasil AI, Vasil ML.

Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8312-7. Epub 2002 May 28.


Siderophore-mediated signaling regulates virulence factor production in Pseudomonasaeruginosa.

Lamont IL, Beare PA, Ochsner U, Vasil AI, Vasil ML.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):7072-7. Epub 2002 May 7.


Characterization of an endoprotease (PrpL) encoded by a PvdS-regulated gene in Pseudomonas aeruginosa.

Wilderman PJ, Vasil AI, Johnson Z, Wilson MJ, Cunliffe HE, Lamont IL, Vasil ML.

Infect Immun. 2001 Sep;69(9):5385-94.


Pseudomonas aeruginosa hemolytic phospholipase C suppresses neutrophil respiratory burst activity.

Terada LS, Johansen KA, Nowbar S, Vasil AI, Vasil ML.

Infect Immun. 1999 May;67(5):2371-6.


Pseudomonas aeruginosa fur overlaps with a gene encoding a novel outer membrane lipoprotein, OmlA.

Ochsner UA, Vasil AI, Johnson Z, Vasil ML.

J Bacteriol. 1999 Feb;181(4):1099-109.


PlcR1 and PlcR2 are putative calcium-binding proteins required for secretion of the hemolytic phospholipase C of Pseudomonas aeruginosa.

Cota-Gomez A, Vasil AI, Kadurugamuwa J, Beveridge TJ, Schweizer HP, Vasil ML.

Infect Immun. 1997 Jul;65(7):2904-13.


Phospholipase C: molecular biology and contribution to the pathogenesis of Pseudomonas aeruginosa.

Vasil ML, Graham LM, Ostroff RM, Shortridge VD, Vasil AI.

Antibiot Chemother (1971). 1991;44:34-47. Review. No abstract available.


Molecular analysis of hemolytic and phospholipase C activities of Pseudomonas cepacia.

Vasil ML, Krieg DP, Kuhns JS, Ogle JW, Shortridge VD, Ostroff RM, Vasil AI.

Infect Immun. 1990 Dec;58(12):4020-9.


Recombinant DNA approaches to the study of the regulation of virulence factors and epidemiology of Pseudomonas aeruginosa.

Vasil ML, Ogle JW, Grant CC, Vasil AI.

Antibiot Chemother (1971). 1987;39:264-78. Review. No abstract available.


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