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Items: 10

1.

A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma.

Vashisht Gopal YN, Gammon S, Prasad R, Knighton B, Pisaneschi F, Roszik J, Feng N, Johnson S, Pramanik S, Sudderth J, Sui D, Hudgens C, Fischer GM, Deng W, Reuben A, Peng W, Wang J, McQuade JL, Tetzlaff MT, Di Francesco ME, Marszalek J, Piwnica-Worms D, DeBerardinis RJ, Davies MA.

Clin Cancer Res. 2019 Nov 1;25(21):6429-6442. doi: 10.1158/1078-0432.CCR-19-0836. Epub 2019 Aug 22.

PMID:
31439581
2.

Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases.

Fischer GM, Jalali A, Kircher DA, Lee WC, McQuade JL, Haydu LE, Joon AY, Reuben A, de Macedo MP, Carapeto FCL, Yang C, Srivastava A, Ambati CR, Sreekumar A, Hudgens CW, Knighton B, Deng W, Ferguson SD, Tawbi HA, Glitza IC, Gershenwald JE, Vashisht Gopal YN, Hwu P, Huse JT, Wargo JA, Futreal PA, Putluri N, Lazar AJ, DeBerardinis RJ, Marszalek JR, Zhang J, Holmen SL, Tetzlaff MT, Davies MA.

Cancer Discov. 2019 May;9(5):628-645. doi: 10.1158/2159-8290.CD-18-1489. Epub 2019 Feb 20.

3.

Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications.

Fischer GM, Vashisht Gopal YN, McQuade JL, Peng W, DeBerardinis RJ, Davies MA.

Pigment Cell Melanoma Res. 2018 Jan;31(1):11-30. doi: 10.1111/pcmr.12661. Epub 2017 Nov 2. Review.

4.

Counteracting oxidative phosphorylation-mediated resistance of melanomas to MAPK pathway inhibition.

McQuade JL, Vashisht Gopal Y.

Mol Cell Oncol. 2015 Jan 23;2(3):e991610. doi: 10.4161/23723556.2014.991610. eCollection 2015 Jul-Sep.

5.

Constitutive and inducible nuclear factor-kappaB in immortalized normal human bronchial epithelial and non-small cell lung cancer cell lines.

Baby J, Pickering BF, Vashisht Gopal YN, Van Dyke MW.

Cancer Lett. 2007 Sep 18;255(1):85-94. Epub 2007 May 9.

PMID:
17493745
6.

Tumour necrosis factor-alpha depletes histone deacetylase 1 protein through IKK2.

Vashisht Gopal YN, Arora TS, Van Dyke MW.

EMBO Rep. 2006 Mar;7(3):291-6. Epub 2005 Dec 23.

7.

Combinatorial determination of sequence specificity for nanomolar DNA-binding hairpin polyamides.

Vashisht Gopal YN, Van Dyke MW.

Biochemistry. 2003 Jun 10;42(22):6891-903.

PMID:
12779344
8.

Topoisomerase II antagonism and anticancer activity of coordinated derivatives of [RuCl(2)(C(6)H(6))(dmso)].

Vashisht Gopal YN, Konuru N, Kondapi AK.

Arch Biochem Biophys. 2002 May 1;401(1):53-62.

PMID:
12054487
9.

Topoisomerase II poisoning by indazole and imidazole complexes of ruthenium.

Vashisht Gopal YN, Kondapi AK.

J Biosci. 2001 Jun;26(2):271-6.

10.

Topoisomerase II poisoning and antineoplastic action by DNA-nonbinding diacetyl and dicarboxaldoxime derivatives of ferrocene.

Vashisht Gopal YN, Jayaraju D, Kondapi AK.

Arch Biochem Biophys. 2000 Apr 1;376(1):229-35.

PMID:
10729210

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