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Items: 39

1.

Rapid, Loop-Mediated Isothermal Amplification Detection of Celiac Disease Risk Alleles.

Erlichster M, Tye-Din JA, Varney MD, Skafidas E, Kwan P.

J Mol Diagn. 2018 May;20(3):307-315. doi: 10.1016/j.jmoldx.2018.01.005. Epub 2018 Feb 17.

PMID:
29458095
2.

Resolving incomplete single nucleotide polymorphism tagging of HLA-DQ2.2 for coeliac disease genotyping using digital droplet PCR.

Hardy MY, Ontiveros N, Varney MD, Tye-Din JA.

HLA. 2018 Apr;91(4):280-288. doi: 10.1111/tan.13219. Epub 2018 Feb 26.

PMID:
29364577
3.

Appropriate clinical use of human leukocyte antigen typing for coeliac disease: an Australasian perspective.

Tye-Din JA, Cameron DJ, Daveson AJ, Day AS, Dellsperger P, Hogan C, Newnham ED, Shepherd SJ, Steele RH, Wienholt L, Varney MD.

Intern Med J. 2015 Apr;45(4):441-50. doi: 10.1111/imj.12716.

4.

Higher body mass index in adults at diagnosis of the slowly progressive form of type 1 diabetes mellitus is associated with lower risk HLA genes.

Fourlanos S, Elkassaby S, Varney MD, Colman PG, Harrison LC.

Diabetes Res Clin Pract. 2014 Jun;104(3):e69-71. doi: 10.1016/j.diabres.2014.03.009. Epub 2014 Mar 18.

PMID:
24698405
5.

Receiver operating characteristic analysis of HLA, CTLA4, and insulin genotypes for type 1 diabetes.

Valdes AM, Varney MD, Erlich HA, Noble JA.

Diabetes Care. 2013 Sep;36(9):2504-7. doi: 10.2337/dc12-2284. Epub 2013 Apr 29.

6.

Common and well-documented HLA alleles: 2012 update to the CWD catalogue.

Mack SJ, Cano P, Hollenbach JA, He J, Hurley CK, Middleton D, Moraes ME, Pereira SE, Kempenich JH, Reed EF, Setterholm M, Smith AG, Tilanus MG, Torres M, Varney MD, Voorter CE, Fischer GF, Fleischhauer K, Goodridge D, Klitz W, Little AM, Maiers M, Marsh SG, Müller CR, Noreen H, Rozemuller EH, Sanchez-Mazas A, Senitzer D, Trachtenberg E, Fernandez-Vina M.

Tissue Antigens. 2013 Apr;81(4):194-203. doi: 10.1111/tan.12093.

7.

Definition of high-risk type 1 diabetes HLA-DR and HLA-DQ types using only three single nucleotide polymorphisms.

Nguyen C, Varney MD, Harrison LC, Morahan G.

Diabetes. 2013 Jun;62(6):2135-40. doi: 10.2337/db12-1398. Epub 2013 Feb 1.

8.

Methods for diagnostic HLA typing in disease association and drug hypersensitivity.

Varney MD, Castley AS, Haimila K, Saavalainen P.

Methods Mol Biol. 2012;882:27-46. doi: 10.1007/978-1-61779-842-9_3.

PMID:
22665227
9.

A community standard for immunogenomic data reporting and analysis: proposal for a STrengthening the REporting of Immunogenomic Studies statement.

Hollenbach JA, Mack SJ, Gourraud PA, Single RM, Maiers M, Middleton D, Thomson G, Marsh SG, Varney MD; Immunogenomics Data Analysis Working Group.

Tissue Antigens. 2011 Nov;78(5):333-44. doi: 10.1111/j.1399-0039.2011.01777.x.

10.

A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis.

Field J, Browning SR, Johnson LJ, Danoy P, Varney MD, Tait BD, Gandhi KS, Charlesworth JC, Heard RN; Australia and New Zealand Multiple Sclerosis Genetics Consortium, Stewart GJ, Kilpatrick TJ, Foote SJ, Bahlo M, Butzkueven H, Wiley J, Booth DR, Taylor BV, Brown MA, Rubio JP, Stankovich J.

PLoS One. 2010 Oct 26;5(10):e13454. doi: 10.1371/journal.pone.0013454.

11.

HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium.

Noble JA, Valdes AM, Varney MD, Carlson JA, Moonsamy P, Fear AL, Lane JA, Lavant E, Rappner R, Louey A, Concannon P, Mychaleckyj JC, Erlich HA; Type 1 Diabetes Genetics Consortium.

Diabetes. 2010 Nov;59(11):2972-9. doi: 10.2337/db10-0699. Epub 2010 Aug 26.

12.

Collection and processing of whole blood for transformation of peripheral blood mononuclear cells and extraction of DNA: the Type 1 Diabetes Genetics Consortium.

Rosinger S, Nutland S, Mickelson E, Varney MD, Boehm BO, Olsem GJ, Hansen JA, Nicholson I, Hilner JE, Perdue LH, Pierce JJ, Akolkar B, Nierras C, Steffes MW; T1DGC.

Clin Trials. 2010;7(1 Suppl):S65-74. doi: 10.1177/1740774510373493. Epub 2010 Jul 1.

13.

HLA genotyping in the international Type 1 Diabetes Genetics Consortium.

Mychaleckyj JC, Noble JA, Moonsamy PV, Carlson JA, Varney MD, Post J, Helmberg W, Pierce JJ, Bonella P, Fear AL, Lavant E, Louey A, Boyle S, Lane JA, Sali P, Kim S, Rappner R, Williams DT, Perdue LH, Reboussin DM, Tait BD, Akolkar B, Hilner JE, Steffes MW, Erlich HA; T1DGC.

Clin Trials. 2010;7(1 Suppl):S75-87. doi: 10.1177/1740774510373494. Epub 2010 Jul 1.

14.

HLA DPA1, DPB1 alleles and haplotypes contribute to the risk associated with type 1 diabetes: analysis of the type 1 diabetes genetics consortium families.

Varney MD, Valdes AM, Carlson JA, Noble JA, Tait BD, Bonella P, Lavant E, Fear AL, Louey A, Moonsamy P, Mychaleckyj JC, Erlich H; Type 1 Diabetes Genetics Consortium.

Diabetes. 2010 Aug;59(8):2055-62. doi: 10.2337/db09-0680. Epub 2010 Apr 27. Erratum in: Diabetes. 2011 Dec;60(12):3308-10.

15.

Differential dynamics of donor DC and non-DC peripheral blood mononuclear cell microchimerism in lung transplantation.

Van der Meulen J, Mifsud NA, Abud D, Paul E, Varney MD, Lewin SR, Cameron PU, Kotsimbos TC.

Clin Immunol. 2009 Nov;133(2):179-83. doi: 10.1016/j.clim.2009.07.012. Epub 2009 Aug 19.

PMID:
19695959
16.

HLA-DRB1 associations with disease susceptibility and clinical course in Australians with multiple sclerosis.

Stankovich J, Butzkueven H, Marriott M, Chapman C, Tubridy N, Tait BD, Varney MD, Taylor BV, Foote SJ; ANZgene Consortium, Kilpatrick TJ, Rubio JP.

Tissue Antigens. 2009 Jul;74(1):17-21. doi: 10.1111/j.1399-0039.2009.01262.x. Epub 2009 Apr 21.

PMID:
19392788
17.

Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in Australians.

Rubio JP, Stankovich J, Field J, Tubridy N, Marriott M, Chapman C, Bahlo M, Perera D, Johnson LJ, Tait BD, Varney MD, Speed TP, Taylor BV, Foote SJ, Butzkueven H, Kilpatrick TJ.

Genes Immun. 2008 Oct;9(7):624-30. doi: 10.1038/gene.2008.59. Epub 2008 Jul 24.

PMID:
18650830
18.

The rising incidence of type 1 diabetes is accounted for by cases with lower-risk human leukocyte antigen genotypes.

Fourlanos S, Varney MD, Tait BD, Morahan G, Honeyman MC, Colman PG, Harrison LC.

Diabetes Care. 2008 Aug;31(8):1546-9. doi: 10.2337/dc08-0239. Epub 2008 May 16.

19.

SNP mapping and candidate gene sequencing in the class I region of the HLA complex: searching for multiple sclerosis susceptibility genes in Tasmanians.

Burfoot RK, Jensen CJ, Field J, Stankovich J, Varney MD, Johnson LJ, Butzkueven H, Booth D, Bahlo M, Tait BD, Taylor BV, Speed TP, Heard R, Stewart GJ, Foote SJ, Kilpatrick TJ, Rubio JP.

Tissue Antigens. 2008 Jan;71(1):42-50. Epub 2007 Oct 30.

PMID:
17971048
20.

Clinical, laboratory and genetic markers associated with erosions and remission in patients with early inflammatory arthritis: a prospective cohort study.

Stockman A, Tait BD, Wolfe R, Brand CA, Rowley MJ, Varney MD, Buchbinder R, Muirden KD.

Rheumatol Int. 2006 Apr;26(6):500-9. Epub 2005 Sep 7.

PMID:
16151812
21.
22.

Polymorphism in the regulatory regions of the HLA-DPB1 gene.

Varney MD, Gavrilidis A, Tait BD.

Hum Immunol. 1999 Oct;60(10):955-61.

PMID:
10566595
23.

HLA-DPB1 alleles in house dust mite allergic patients.

O'Brien RM, Tait BD, Varney MD, Thomas WR.

Eur J Immunogenet. 1999 Aug;26(4):281-4.

PMID:
10457892
24.

Matching for HLA DPA1 and DPB1 alleles in unrelated bone marrow transplantation.

Varney MD, Lester S, McCluskey J, Gao X, Tait BD.

Hum Immunol. 1999 Jun;60(6):532-8.

PMID:
10408803
25.

A novel strategy for unambiguous DPB1 typing.

Varney MD, Tait BD.

Eur J Immunogenet. 1998 Oct;25(5):371-4.

PMID:
9805660
26.

Protein structure-based design, synthesis, and biological evaluation of 5-thia-2,6-diamino-4(3H)-oxopyrimidines: potent inhibitors of glycinamide ribonucleotide transformylase with potent cell growth inhibition.

Varney MD, Palmer CL, Romines WH 3rd, Boritzki T, Margosiak SA, Almassy R, Janson CA, Bartlett C, Howland EJ, Ferre R.

J Med Chem. 1997 Aug 1;40(16):2502-24.

PMID:
9258357
27.

Structure-based design of substituted diphenyl sulfones and sulfoxides as lipophilic inhibitors of thymidylate synthase.

Jones TR, Webber SE, Varney MD, Reddy MR, Lewis KK, Kathardekar V, Mazdiyasni H, Deal J, Nguyen D, Welsh KM, Webber S, Johnston A, Matthews DA, Smith WW, Janson CA, Bacquet RJ, Howland EF, Booth CL, Herrmann SM, Ward RW, White J, Bartlett CA, Morse CA.

J Med Chem. 1997 Feb 28;40(5):677-83.

PMID:
9057854
28.

Structure-based design of lipophilic quinazoline inhibitors of thymidylate synthase.

Jones TR, Varney MD, Webber SE, Lewis KK, Marzoni GP, Palmer CL, Kathardekar V, Welsh KM, Webber S, Matthews DA, Appelt K, Smith WW, Janson CA, Villafranca JE, Bacquet RJ, Howland EF, Booth CL, Herrmann SM, Ward RW, White J, Moomaw EW, Bartlett CA, Morse CA.

J Med Chem. 1996 Feb 16;39(4):904-17.

PMID:
8632414
29.
30.

Identification of DRB1*0422--implications for serological epitopes.

Varney MD, Kanaan C, Tait BD.

Tissue Antigens. 1996 Feb;47(2):150-2. No abstract available.

PMID:
8851731
31.

HLA-DRB1*0401 is associated with susceptibility to insulin-dependent diabetes mellitus independently of the DQB1 locus.

Tait BD, Drummond BP, Varney MD, Harrison LC.

Eur J Immunogenet. 1995 Aug;22(4):289-97.

PMID:
7495781
32.

Synthesis and biological evaluation of novel 2,6-diaminobenz[cd]indole inhibitors of thymidylate synthase using the protein structure as a guide.

Varney MD, Palmer CL, Deal JG, Webber S, Welsh KM, Bartlett CA, Morse CA, Smith WW, Janson CA.

J Med Chem. 1995 May 26;38(11):1892-903.

PMID:
7783121
33.

Molecular typing and haplotypic associations of HLA-B*44 subtypes.

Varney MD, Boyle AJ, Tait BD.

Eur J Immunogenet. 1995 Apr;22(2):215-20.

PMID:
7605780
34.

HLA antigens and age at diagnosis of insulin-dependent diabetes mellitus.

Tait BD, Harrison LC, Drummond BP, Stewart V, Varney MD, Honeyman MC.

Hum Immunol. 1995 Feb;42(2):116-22.

PMID:
7744614
35.

Crystal-structure-based design and synthesis of novel C-terminal inhibitors of HIV protease.

Varney MD, Appelt K, Kalish V, Reddy MR, Tatlock J, Palmer CL, Romines WH, Wu BW, Musick L.

J Med Chem. 1994 Jul 22;37(15):2274-84.

PMID:
8057276
36.

Calculation of relative differences in the binding free energies of HIV1 protease inhibitors: a thermodynamic cycle perturbation approach.

Reddy MR, Varney MD, Kalish V, Viswanadhan VN, Appelt K.

J Med Chem. 1994 Apr 15;37(8):1145-52.

PMID:
8164256
37.

Application of the three-dimensional structures of protein target molecules in structure-based drug design.

Greer J, Erickson JW, Baldwin JJ, Varney MD.

J Med Chem. 1994 Apr 15;37(8):1035-54. Review. No abstract available.

PMID:
8164249
38.

The presence of high-titer HLA antibodies in cardiac transplant recipients.

Varney MD, Tait BD, Cochrane AD, Smith JA, Benson E, Esmore DS.

Transplantation. 1992 Dec;54(6):1123-5. No abstract available.

PMID:
1465784
39.

Crystal-structure-based design and synthesis of benz[cd]indole-containing inhibitors of thymidylate synthase.

Varney MD, Marzoni GP, Palmer CL, Deal JG, Webber S, Welsh KM, Bacquet RJ, Bartlett CA, Morse CA, Booth CL, et al.

J Med Chem. 1992 Feb 21;35(4):663-76.

PMID:
1542093

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