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Items: 14

1.

A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme A production.

Chung CC, Ohwaki K, Schneeweis JE, Stec E, Varnerin JP, Goudreau PN, Chang A, Cassaday J, Yang L, Yamakawa T, Kornienko O, Hodder P, Inglese J, Ferrer M, Strulovici B, Kusunoki J, Tota MR, Takagi T.

Assay Drug Dev Technol. 2008 Jun;6(3):361-74. doi: 10.1089/adt.2007.105.

PMID:
18452391
2.

3-Aryl-4-hydroxyquinolin-2(1H)-one derivatives as type I fatty acid synthase inhibitors.

Rivkin A, Kim YR, Goulet MT, Bays N, Hill AD, Kariv I, Krauss S, Ginanni N, Strack PR, Kohl NE, Chung CC, Varnerin JP, Goudreau PN, Chang A, Tota MR, Munoz B.

Bioorg Med Chem Lett. 2006 Sep 1;16(17):4620-3. Epub 2006 Jun 19.

PMID:
16784844
3.

Crystal structure of human phosphodiesterase 3B: atomic basis for substrate and inhibitor specificity.

Scapin G, Patel SB, Chung C, Varnerin JP, Edmondson SD, Mastracchio A, Parmee ER, Singh SB, Becker JW, Van der Ploeg LH, Tota MR.

Biochemistry. 2004 May 25;43(20):6091-100.

PMID:
15147193
4.

Expression, refolding, and purification of recombinant human phosphodiesterase 3B: definition of the N-terminus of the catalytic core.

Varnerin JP, Chung CC, Patel SB, Scapin G, Parmee ER, Morin NR, MacNeil DJ, Cully DF, Van der Ploeg LH, Tota MR.

Protein Expr Purif. 2004 Jun;35(2):225-36.

PMID:
15135397
5.

Crystallization and preliminary X-ray diffraction analysis of the catalytic domain of recombinant human phosphodiesterase 3B.

Patel SB, Varnerin JP, Tota MR, Edmondson SD, Parmee ER, Becker JW, Scapin G.

Acta Crystallogr D Biol Crystallogr. 2004 Jan;60(Pt 1):169-71. Epub 2003 Dec 18.

PMID:
14684919
6.

Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors.

Edmondson SD, Mastracchio A, He J, Chung CC, Forrest MJ, Hofsess S, MacIntyre E, Metzger J, O'Connor N, Patel K, Tong X, Tota MR, Van der Ploeg LH, Varnerin JP, Fisher MH, Wyvratt MJ, Weber AE, Parmee ER.

Bioorg Med Chem Lett. 2003 Nov 17;13(22):3983-7.

PMID:
14592490
7.

The role of tryptophan 1072 in human PDE3B inhibitor binding.

Chung C, Varnerin JP, Morin NR, MacNeil DJ, Singh SB, Patel S, Scapin G, Van der Ploeg LH, Tota MR.

Biochem Biophys Res Commun. 2003 Aug 8;307(4):1045-50.

PMID:
12878217
8.

Mass spectrometric mapping of disulfide bonds in recombinant human interleukin-13.

Tsarbopoulos A, Varnerin J, Cannon-Carlson S, Wylie D, Pramanik B, Tang J, Nagabhushan TL.

J Mass Spectrom. 2000 Mar;35(3):446-53.

PMID:
10767776
9.

Production of leptin in Escherichia coli: a comparison of methods.

Varnerin JP, Smith T, Rosenblum CI, Vongs A, Murphy BA, Nunes C, Mellin TN, King JJ, Burgess BW, Junker B, Chou M, Hey P, Frazier E, MacIntyre DE, Van der Ploeg LH, Tota MR.

Protein Expr Purif. 1998 Dec;14(3):335-42.

PMID:
9882567
10.

A rapid, quantitative functional assay for measuring leptin.

Rosenblum CI, Vongs A, Tota MR, Varnerin JP, Frazier E, Cully DF, Morsy MA, Van der Ploeg LH.

Mol Cell Endocrinol. 1998 Aug 25;143(1-2):117-23.

PMID:
9806356
11.

Expression, purification, and characterization of recombinant human interleukin-13 from NS-O cells.

Cannon-Carlson S, Varnerin J, Tsarbopoulos A, Jenh CH, Cox MA, Chou CC, Connelly N, Zavodny P, Tang JC.

Protein Expr Purif. 1998 Mar;12(2):239-48.

PMID:
9518466
12.

Localization of leptin binding domain in the leptin receptor.

Fong TM, Huang RR, Tota MR, Mao C, Smith T, Varnerin J, Karpitskiy VV, Krause JE, Van der Ploeg LH.

Mol Pharmacol. 1998 Feb;53(2):234-40.

PMID:
9463481
13.

Independent and additive effects of central POMC and leptin pathways on murine obesity.

Boston BA, Blaydon KM, Varnerin J, Cone RD.

Science. 1997 Nov 28;278(5343):1641-4.

14.

Resolution of recombinant human interleukin 10 from variants by recycling free flow focusing.

Bondoc LL Jr, Varnerin JP, Tang JC.

Anal Biochem. 1997 Mar 15;246(2):234-8.

PMID:
9073361

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