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Items: 1 to 50 of 313

1.

Analysis of the role of thrombomodulin in all-trans retinoic acid treatment of coagulation disorders in cancer patients.

Ghaffari H, Varner JD, Petzold LR.

Theor Biol Med Model. 2019 Feb 14;16(1):3. doi: 10.1186/s12976-019-0099-z.

2.

Allometry of the pyrophytic Aristida in fire-maintained longleaf pine-wiregrass ecosystems.

Shearman TM, Varner JM, Robertson K, Hiers JK.

Am J Bot. 2019 Jan;106(1):18-28. doi: 10.1002/ajb2.1215. Epub 2019 Jan 10.

PMID:
30629749
3.

Linking ecosystem function and hydrologic regime to inform restoration of a forested peatland.

Schulte ML, McLaughlin DL, Wurster FC, Balentine K, Speiran GK, Aust WM, Stewart RD, Varner JM, Jones CN.

J Environ Manage. 2019 Mar 1;233:342-351. doi: 10.1016/j.jenvman.2018.12.042. Epub 2018 Dec 31.

PMID:
30590264
4.

Retinoic acid and 6-formylindolo(3,2-b)carbazole (FICZ) combination therapy reveals putative targets for enhancing response in non-APL AML.

Bunaciu RP, MacDonald RJ, Jensen HA, Gao F, Wang X, Johnson L, Varner JD, Yen A.

Leuk Lymphoma. 2018 Dec 20:1-12. doi: 10.1080/10428194.2018.1543880. [Epub ahead of print]

PMID:
30570341
5.

Integrin CD11b activation drives anti-tumor innate immunity.

Schmid MC, Khan SQ, Kaneda MM, Pathria P, Shepard R, Louis TL, Anand S, Woo G, Leem C, Faridi MH, Geraghty T, Rajagopalan A, Gupta S, Ahmed M, Vazquez-Padron RI, Cheresh DA, Gupta V, Varner JA.

Nat Commun. 2018 Dec 19;9(1):5379. doi: 10.1038/s41467-018-07387-4.

6.

Multi-scale computational study of the Warburg effect, reverse Warburg effect and glutamine addiction in solid tumors.

Shan M, Dai D, Vudem A, Varner JD, Stroock AD.

PLoS Comput Biol. 2018 Dec 7;14(12):e1006584. doi: 10.1371/journal.pcbi.1006584. eCollection 2018 Dec.

7.

Correction to: Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings : A Midwest Pediatric Nephrology Consortium (MWPNC) study.

Pelletier JH, Kumar KR, Engen R, Bensimhon A, Varner JD, Rheault MN, Srivastava T, Straatmann C, Silva C, Davis TK, Wenderfer SE, Gibson K, Selewski D, Barcia J, Weng P, Licht C, Jawa N, Kallash M, Foreman JW, Wigfall DR, Chua AN, Chambers E, Hornik CP, Brewer ED, Nagaraj SK, Greenbaum LA, Gbadegesin RA.

Pediatr Nephrol. 2019 Mar;34(3):539. doi: 10.1007/s00467-018-4103-3.

PMID:
30443740
8.

Genetic Testing for Steroid-Resistant-Nephrotic Syndrome in an Outbred Population.

Varner JD, Chryst-Stangl M, Esezobor CI, Solarin A, Wu G, Lane B, Hall G, Abeyagunawardena A, Matory A, Hunley TE, Lin JJ, Howell D, Gbadegesin R.

Front Pediatr. 2018 Oct 22;6:307. doi: 10.3389/fped.2018.00307. eCollection 2018.

9.

Genetic Basis of Health Disparity in Childhood Nephrotic Syndrome.

Varner JD, Matory A, Gbadegesin RA.

Am J Kidney Dis. 2018 Nov;72(5S1):S22-S25. doi: 10.1053/j.ajkd.2018.06.022.

PMID:
30343718
10.

Dynamic Optimization with Particle Swarms (DOPS): a meta-heuristic for parameter estimation in biochemical models.

Sagar A, LeCover R, Shoemaker C, Varner J.

BMC Syst Biol. 2018 Oct 12;12(1):87. doi: 10.1186/s12918-018-0610-x.

11.

Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings.

Pelletier JH, Kumar KR, Engen R, Bensimhon A, Varner JD, Rheault MN, Srivastava T, Straatmann C, Silva C, Davis TK, Wenderfer SE, Gibson K, Selewski D, Barcia J, Weng P, Licht C, Jawa N, Kallash M, Foreman JW, Wigfall DR, Chua AN, Chambers E, Hornik CP, Brewer ED, Nagaraj SK, Greenbaum LA, Gbadegesin RA.

Pediatr Nephrol. 2018 Oct;33(10):1773-1780. doi: 10.1007/s00467-018-3994-3. Epub 2018 Jul 7. Erratum in: Pediatr Nephrol. 2019 Mar;34(3):539.

PMID:
29982878
12.

Sequence Specific Modeling of E. coli Cell-Free Protein Synthesis.

Vilkhovoy M, Horvath N, Shih CH, Wayman JA, Calhoun K, Swartz J, Varner JD.

ACS Synth Biol. 2018 Aug 17;7(8):1844-1857. doi: 10.1021/acssynbio.7b00465. Epub 2018 Jul 16.

PMID:
29944340
13.

Src family kinase inhibitor bosutinib enhances retinoic acid-induced differentiation of HL-60 leukemia cells.

MacDonald RJ, Bunaciu RP, Ip V, Dai D, Tran D, Varner JD, Yen A.

Leuk Lymphoma. 2018 Dec;59(12):2941-2951. doi: 10.1080/10428194.2018.1452213. Epub 2018 Mar 23.

PMID:
29569971
14.

Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment.

Bunaciu RP, MacDonald RJ, Gao F, Johnson LM, Varner JD, Wang X, Nataraj S, Guzman ML, Yen A.

Oncotarget. 2017 Dec 23;9(3):4134-4149. doi: 10.18632/oncotarget.23642. eCollection 2018 Jan 9.

15.

Reduced order modeling and analysis of the human complement system.

Sagar A, Dai W, Minot M, LeCover R, Varner JD.

PLoS One. 2017 Nov 20;12(11):e0187373. doi: 10.1371/journal.pone.0187373. eCollection 2017.

16.

An Effective Model of the Retinoic Acid Induced HL-60 Differentiation Program.

Tasseff R, Jensen HA, Congleton J, Dai D, Rogers KV, Sagar A, Bunaciu RP, Yen A, Varner JD.

Sci Rep. 2017 Oct 30;7(1):14327. doi: 10.1038/s41598-017-14523-5.

17.

PI3Kγ Activates Integrin α4 and Promotes Immune Suppressive Myeloid Cell Polarization during Tumor Progression.

Foubert P, Kaneda MM, Varner JA.

Cancer Immunol Res. 2017 Nov;5(11):957-968. doi: 10.1158/2326-6066.CIR-17-0143. Epub 2017 Sep 28.

18.

Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.

Sato-Kaneko F, Yao S, Ahmadi A, Zhang SS, Hosoya T, Kaneda MM, Varner JA, Pu M, Messer KS, Guiducci C, Coffman RL, Kitaura K, Matsutani T, Suzuki R, Carson DA, Hayashi T, Cohen EE.

JCI Insight. 2017 Sep 21;2(18). pii: 93397. doi: 10.1172/jci.insight.93397. eCollection 2017 Sep 21.

19.

Gut microbial communities of American pikas (Ochotona princeps): Evidence for phylosymbiosis and adaptations to novel diets.

Kohl KD, Varner J, Wilkening JL, Dearing MD.

J Anim Ecol. 2018 Mar;87(2):323-330. doi: 10.1111/1365-2656.12692. Epub 2017 Jun 26.

PMID:
28502120
20.

JuPOETs: a constrained multiobjective optimization approach to estimate biochemical model ensembles in the Julia programming language.

Bassen DM, Vilkhovoy M, Minot M, Butcher JT, Varner JD.

BMC Syst Biol. 2017 Jan 25;11(1):10. doi: 10.1186/s12918-016-0380-2.

21.

Population Heterogeneity in the Epithelial to Mesenchymal Transition Is Controlled by NFAT and Phosphorylated Sp1.

Gould R, Bassen DM, Chakrabarti A, Varner JD, Butcher J.

PLoS Comput Biol. 2016 Dec 27;12(12):e1005251. doi: 10.1371/journal.pcbi.1005251. eCollection 2016 Dec.

22.

Corrigendum: PI3Kγ is a molecular switch that controls immune suppression.

Kaneda MM, Messer KS, Ralainirina N, Li H, Leem CJ, Gorjestani S, Woo G, Nguyen AV, Figueiredo CC, Foubert P, Schmid MC, Pink M, Winkler DG, Rausch M, Palombella VJ, Kutok J, McGovern K, Frazer KA, Wu X, Karin M, Sasik R, Cohen EE, Varner JA.

Nature. 2017 Feb 2;542(7639):124. doi: 10.1038/nature21026. Epub 2016 Dec 14. No abstract available.

PMID:
27974794
23.

PI3Kγ is a molecular switch that controls immune suppression.

Kaneda MM, Messer KS, Ralainirina N, Li H, Leem CJ, Gorjestani S, Woo G, Nguyen AV, Figueiredo CC, Foubert P, Schmid MC, Pink M, Winkler DG, Rausch M, Palombella VJ, Kutok J, McGovern K, Frazer KA, Wu X, Karin M, Sasik R, Cohen EE, Varner JA.

Nature. 2016 Nov 17;539(7629):437-442. doi: 10.1038/nature19834. Epub 2016 Sep 19. Erratum in: Nature. 2017 Feb 2;542(7639):124.

24.

Acupuncture for Menopausal Hot Flashes.

Varner J.

Ann Intern Med. 2016 Sep 20;165(6):450. doi: 10.7326/L16-0198. No abstract available.

PMID:
27653712
25.

Differential Contributions of Intrinsic and Extrinsic Pathways to Thrombin Generation in Adult, Maternal and Cord Plasma Samples.

Rice NT, Szlam F, Varner JD, Bernstein PS, Szlam AD, Tanaka KA.

PLoS One. 2016 May 19;11(5):e0154127. doi: 10.1371/journal.pone.0154127. eCollection 2016.

26.

Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.

Kaneda MM, Cappello P, Nguyen AV, Ralainirina N, Hardamon CR, Foubert P, Schmid MC, Sun P, Mose E, Bouvet M, Lowy AM, Valasek MA, Sasik R, Novelli F, Hirsch E, Varner JA.

Cancer Discov. 2016 Aug;6(8):870-85. doi: 10.1158/2159-8290.CD-15-1346. Epub 2016 May 13.

27.

Plastic pikas: Behavioural flexibility in low-elevation pikas (Ochotona princeps).

Varner J, Horns JJ, Lambert MS, Westberg E, Ruff JS, Wolfenberger K, Beever EA, Dearing MD.

Behav Processes. 2016 Apr;125:63-71. doi: 10.1016/j.beproc.2016.01.009. Epub 2016 Feb 3.

PMID:
26851456
28.

When can we measure stress noninvasively? Postdeposition effects on a fecal stress metric confound a multiregional assessment.

Wilkening JL, Ray C, Varner J.

Ecol Evol. 2016 Jan 9;6(2):502-13. doi: 10.1002/ece3.1857. eCollection 2016 Jan.

29.

Prevalence of Monogenic Causes in Pediatric Patients with Nephrolithiasis or Nephrocalcinosis.

Braun DA, Lawson JA, Gee HY, Halbritter J, Shril S, Tan W, Stein D, Wassner AJ, Ferguson MA, Gucev Z, Fisher B, Spaneas L, Varner J, Sayer JA, Milosevic D, Baum M, Tasic V, Hildebrandt F.

Clin J Am Soc Nephrol. 2016 Apr 7;11(4):664-72. doi: 10.2215/CJN.07540715. Epub 2016 Jan 19.

30.

Bruton Tyrosine Kinase-Dependent Immune Cell Cross-talk Drives Pancreas Cancer.

Gunderson AJ, Kaneda MM, Tsujikawa T, Nguyen AV, Affara NI, Ruffell B, Gorjestani S, Liudahl SM, Truitt M, Olson P, Kim G, Hanahan D, Tempero MA, Sheppard B, Irving B, Chang BY, Varner JA, Coussens LM.

Cancer Discov. 2016 Mar;6(3):270-85. doi: 10.1158/2159-8290.CD-15-0827. Epub 2015 Dec 29. Erratum in: Cancer Discov. 2016 Jul;6(7):802.

31.

Induced myelomonocytic differentiation in leukemia cells is accompanied by noncanonical transcription factor expression.

Jensen HA, Yourish HB, Bunaciu RP, Varner JD, Yen A.

FEBS Open Bio. 2015 Sep 28;5:789-800. doi: 10.1016/j.fob.2015.09.008. eCollection 2015.

32.

Allowing and Using Foods of Low Nutritional Value in Elementary School Classrooms: The Implications of Teachers' Beliefs.

Lambert LG, Chang Y, Varner J, Monroe A.

J Nutr Educ Behav. 2016 Feb;48(2):86-92.e1. doi: 10.1016/j.jneb.2015.08.022. Epub 2015 Oct 23.

PMID:
26472631
33.

6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells.

Bunaciu RP, Jensen HA, MacDonald RJ, LaTocha DH, Varner JD, Yen A.

PLoS One. 2015 Aug 19;10(8):e0135668. doi: 10.1371/journal.pone.0135668. eCollection 2015.

34.

Lessons in Medical Record Abstraction from the Prostate, Lung, Colorectal, and Ovarian (PLCO) National Screening Trial.

Bazzi L, Lamerato LE, Varner J, Shambaugh VL, Cordes JE, Ragard LR, Marcus PM.

Rev Recent Clin Trials. 2015;10(3):200-5. Review.

PMID:
26238207
35.

Generating Effective Models and Parameters for RNA Genetic Circuits.

Hu CY, Varner JD, Lucks JB.

ACS Synth Biol. 2015 Aug 21;4(8):914-26. doi: 10.1021/acssynbio.5b00077. Epub 2015 Jul 2.

36.

Integrin α4 Enhances Metastasis and May Be Associated with Poor Prognosis in MYCN-low Neuroblastoma.

Young SA, McCabe KE, Bartakova A, Delaney J, Pizzo DP, Newbury RO, Varner JA, Schlaepfer DD, Stupack DG.

PLoS One. 2015 May 14;10(5):e0120815. doi: 10.1371/journal.pone.0120815. eCollection 2015.

37.

GW5074 and PP2 kinase inhibitors implicate nontraditional c-Raf and Lyn function as drivers of retinoic acid-induced maturation.

Jensen HA, Bunaciu RP, Varner JD, Yen A.

Cell Signal. 2015 Aug;27(8):1666-75. doi: 10.1016/j.cellsig.2015.03.014. Epub 2015 Mar 26.

38.

Relating sub-surface ice features to physiological stress in a climate sensitive mammal, the American pika (Ochotona princeps).

Wilkening JL, Ray C, Varner J.

PLoS One. 2015 Mar 24;10(3):e0119327. doi: 10.1371/journal.pone.0119327. eCollection 2015.

39.

Clarifying the role of fire in the deciduous forests of eastern North America: reply to Matlack.

Stambaugh MC, Varner JM, Noss RF, Dey DC, Christensen NL, Baldwin RF, Guyette RP, Hanberry BB, Harper CA, Lindblom SG, Waldrop TA.

Conserv Biol. 2015 Jun;29(3):942-6. doi: 10.1111/cobi.12473. Epub 2015 Feb 20. No abstract available.

PMID:
25704587
40.

The importance of biologically relevant microclimates in habitat suitability assessments.

Varner J, Dearing MD.

PLoS One. 2014 Aug 12;9(8):e104648. doi: 10.1371/journal.pone.0104648. eCollection 2014.

41.

Altered community flammability in Florida's Apalachicola ravines and implications for the persistence of the endangered conifer Torreya taxifolia.

Mola JM, Varner JM, Jules ES, Spector T.

PLoS One. 2014 Aug 1;9(8):e103933. doi: 10.1371/journal.pone.0103933. eCollection 2014.

42.

Retinoic acid therapy resistance progresses from unilineage to bilineage in HL-60 leukemic blasts.

Jensen HA, Bunaciu RP, Ibabao CN, Myers R, Varner JD, Yen A.

PLoS One. 2014 Jun 12;9(6):e98929. doi: 10.1371/journal.pone.0098929. eCollection 2014.

43.

Long-term effects of fire severity on oak-conifer dynamics in the southern Cascades.

Cocking MI, Varner JM, Knapp EE.

Ecol Appl. 2014 Jan;24(1):94-107.

PMID:
24640537
44.

Toward a mechanism for eastern North American forest mesophication: differential litter drying across 17 species.

Kreye JK, Varner JM, Hiers JK, Mola J.

Ecol Appl. 2013 Dec;23(8):1976-86.

PMID:
24555322
45.

Ubiquibodies, synthetic E3 ubiquitin ligases endowed with unnatural substrate specificity for targeted protein silencing.

Portnoff AD, Stephens EA, Varner JD, DeLisa MP.

J Biol Chem. 2014 Mar 14;289(11):7844-55. doi: 10.1074/jbc.M113.544825. Epub 2014 Jan 28.

46.

Unexpected redwood mortality from synergies between wildfire and an emerging infectious disease.

Metz MR, Varner JM, Frangioso KM, Meentemeyer RK, Rizzo DM.

Ecology. 2013 Oct;94(10):2152-9.

PMID:
24358700
47.

PI3Kα activates integrin α4β1 to establish a metastatic niche in lymph nodes.

Garmy-Susini B, Avraamides CJ, Desgrosellier JS, Schmid MC, Foubert P, Ellies LG, Lowy AM, Blair SL, Vandenberg SR, Datnow B, Wang HY, Cheresh DA, Varner J.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):9042-7. doi: 10.1073/pnas.1219603110. Epub 2013 May 13.

48.

PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth.

Schmid MC, Franco I, Kang SW, Hirsch E, Quilliam LA, Varner JA.

PLoS One. 2013;8(4):e60226. doi: 10.1371/journal.pone.0060226. Epub 2013 Apr 2.

49.

Physicochemical regulation of endothelial sprouting in a 3D microfluidic angiogenesis model.

Verbridge SS, Chakrabarti A, DelNero P, Kwee B, Varner JD, Stroock AD, Fischbach C.

J Biomed Mater Res A. 2013 Oct;101(10):2948-56. doi: 10.1002/jbm.a.34587. Epub 2013 Apr 5.

50.

The Src-family kinase inhibitor PP2 rescues inducible differentiation events in emergent retinoic acid-resistant myeloblastic leukemia cells.

Jensen HA, Styskal LE, Tasseff R, Bunaciu RP, Congleton J, Varner JD, Yen A.

PLoS One. 2013;8(3):e58621. doi: 10.1371/journal.pone.0058621. Epub 2013 Mar 15.

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