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Items: 1 to 50 of 667

1.

PBPK models for evaluating membrane transporter mediated DDIs: Current capabilities, case studies, future opportunities and recommendations.

Taskar K, Pilla Reddy V, Howard B, Posada MM, Varma M, Zheng M, Ullah M, Emami Riedmaier A, Umehara KI, Snoeys J, Nakakariya M, Chu X, Beneton M, Chen Y, Huth F, Narayanan R, Mukherjee D, Dixit V, Sugiyama Y, Neuhoff S.

Clin Pharmacol Ther. 2019 Oct 19. doi: 10.1002/cpt.1693. [Epub ahead of print] Review.

PMID:
31628859
2.

Pathological upgrading in prostate cancer treated with surgery in the United Kingdom: trends and risk factors from the British Association of Urological Surgeons Radical Prostatectomy Registry.

Bullock N, Simpkin A, Fowler S, Varma M, Kynaston H, Narahari K.

BMC Urol. 2019 Oct 17;19(1):94. doi: 10.1186/s12894-019-0526-9.

PMID:
31623595
3.

EAU-EANM-ESTRO-ESUR-SIOG Prostate Cancer Guideline Panel Consensus Statements for Deferred Treatment with Curative Intent for Localised Prostate Cancer from an International Collaborative Study (DETECTIVE Study).

Lam TBL, MacLennan S, Willemse PM, Mason MD, Plass K, Shepherd R, Baanders R, Bangma CH, Bjartell A, Bossi A, Briers E, Briganti A, Buddingh KT, Catto JWF, Colecchia M, Cox BW, Cumberbatch MG, Davies J, Davis NF, De Santis M, Dell'Oglio P, Deschamps A, Donaldson JF, Egawa S, Fankhauser CD, Fanti S, Fossati N, Gandaglia G, Gillessen S, Grivas N, Gross T, Grummet JP, Henry AM, Ingels A, Irani J, Lardas M, Liew M, Lin DW, Moris L, Omar MI, Pang KH, Paterson CC, Renard-Penna R, Ribal MJ, Roobol MJ, Rouprêt M, Rouvière O, Sancho Pardo G, Richenberg J, Schoots IG, Sedelaar JPM, Stricker P, Tilki D, Vahr Lauridsen S, van den Bergh RCN, Van den Broeck T, van der Kwast TH, van der Poel HG, van Leenders GJLH, Varma M, Violette PD, Wallis CJD, Wiegel T, Wilkinson K, Zattoni F, N'Dow JMO, Van Poppel H, Cornford P, Mottet N.

Eur Urol. 2019 Oct 3. pii: S0302-2838(19)30740-7. doi: 10.1016/j.eururo.2019.09.020. [Epub ahead of print] Review.

PMID:
31587989
4.

Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial.

Hausenloy DJ, Kharbanda RK, Møller UK, Ramlall M, Aarøe J, Butler R, Bulluck H, Clayton T, Dana A, Dodd M, Engstrom T, Evans R, Lassen JF, Christensen EF, Garcia-Ruiz JM, Gorog DA, Hjort J, Houghton RF, Ibanez B, Knight R, Lippert FK, Lønborg JT, Maeng M, Milasinovic D, More R, Nicholas JM, Jensen LO, Perkins A, Radovanovic N, Rakhit RD, Ravkilde J, Ryding AD, Schmidt MR, Riddervold IS, Sørensen HT, Stankovic G, Varma M, Webb I, Terkelsen CJ, Greenwood JP, Yellon DM, Bøtker HE; CONDI-2/ERIC-PPCI Investigators.

Lancet. 2019 Sep 6. pii: S0140-6736(19)32039-2. doi: 10.1016/S0140-6736(19)32039-2. [Epub ahead of print]

6.

Physiologically-Based Pharmacokinetic Modeling Approach to Predict Rifampin-Mediated Intestinal P-Glycoprotein Induction.

Yamazaki S, Costales C, Lazzaro S, Eatemadpour S, Kimoto E, Varma MV.

CPT Pharmacometrics Syst Pharmacol. 2019 Sep;8(9):634-642. doi: 10.1002/psp4.12458. Epub 2019 Sep 5.

7.

Anomalous origin of the right coronary artery from the left Valsalva sinus in a patient presenting with syncope, ventricular tachycardia, and electrocardiographic early repolarization pattern.

Majewski J, Shelton R, Varma M, Davis G.

Kardiol Pol. 2019 Sep 23;77(9):883-885. doi: 10.33963/KP.14909. Epub 2019 Jul 25. No abstract available.

8.

DNA Translocation through Hybrid Bilayer Nanopores.

Balasubramanian R, Pal S, Joshi H, Rao A, Naik A, Varma M, Chakraborty B, Maiti PK.

J Phys Chem C Nanomater Interfaces. 2019 May 9;123(18):11908-11916. doi: 10.1021/acs.jpcc.9b00399. Epub 2019 Apr 23.

PMID:
31316684
9.

Controversial issues in Gleason and International Society of Urological Pathology (ISUP) prostate cancer grading: proposed recommendations for international implementation.

Srigley JR, Delahunt B, Samaratunga H, Billis A, Cheng L, Clouston D, Evans A, Furusato B, Kench J, Leite K, MacLennan G, Moch H, Pan CC, Rioux-Leclercq N, Ro J, Shanks J, Shen S, Tsuzuki T, Varma M, Wheeler T, Yaxley J, Egevad L.

Pathology. 2019 Aug;51(5):463-473. doi: 10.1016/j.pathol.2019.05.001. Epub 2019 Jul 3. Review.

PMID:
31279442
10.

Addendum to the Acknowledgements: Validity of Online Screening for Autism: Crowdsourcing Study Comparing Paid and Unpaid Diagnostic Tasks.

Washington P, Kalantarian H, Tariq Q, Schwartz J, Dunlap K, Chrisman B, Varma M, Ning M, Kline A, Stockham N, Paskov K, Voss C, Haber N, Wall DP.

J Med Internet Res. 2019 Jun 27;21(6):e14950. doi: 10.2196/14950.

11.

Cancer Overdiagnosis: Pathologists in the Dock.

Shah V, Scott-Coombes D, Varma M.

Arch Pathol Lab Med. 2019 Jul;143(7):781. doi: 10.5858/arpa.2018-0494-LE. No abstract available.

PMID:
31225994
12.

Is the UICC/AJCC pT2 Staging Category for Clear Cell Renal Cell Carcinoma Meaningful?

Delahunt B, Dagher J, Egevad L, Yaxley J, Varma M, Samaratunga H.

Am J Surg Pathol. 2019 Sep;43(9):1249-1252. doi: 10.1097/PAS.0000000000001308.

PMID:
31219816
13.

Null model exhibiting synchronized dynamics in uncoupled oscillators.

Chakrabortty T, Suman A, Gupta A, Singh V, Varma M.

Phys Rev E. 2019 May;99(5-1):052410. doi: 10.1103/PhysRevE.99.052410.

PMID:
31212412
14.

Data Set for the Reporting of Carcinoma of the Renal Pelvis and Ureter-Nephroureterectomy and Ureterectomy Specimens: Recommendations From the International Collaboration on Cancer Reporting (ICCR).

Samaratunga H, Judge M, Delahunt B, Srigley J, Brimo F, Comperat E, Koch M, Lopez-Beltran A, Reuter V, Shanks J, Tsuzuki T, van der Kwast T, Varma M, Grignon D.

Am J Surg Pathol. 2019 Oct;43(10):e1-e12. doi: 10.1097/PAS.0000000000001305.

PMID:
31192862
15.

Increasing Medical Student Interest in Nephrology.

Sozio SM, Pivert KA, Shah HH, Chakkera HA, Asmar AR, Varma MR, Morrow BD, Patel AB, Leight K, Parker MG.

Am J Nephrol. 2019;50(1):4-10. doi: 10.1159/000501058. Epub 2019 Jun 11.

16.

Measuring reliability and validity of "Stressometer®": A computer-based mass screening and assessment tool for evaluation of stress level and sources of stressors.

Vohra S, Kelling AS, Varma MM, Prakash A, Khurana D.

Indian J Psychiatry. 2019 May-Jun;61(3):295-299. doi: 10.4103/psychiatry.IndianJPsychiatry_429_18.

17.

Validity of Online Screening for Autism: Crowdsourcing Study Comparing Paid and Unpaid Diagnostic Tasks.

Washington P, Kalantarian H, Tariq Q, Schwartz J, Dunlap K, Chrisman B, Varma M, Ning M, Kline A, Stockham N, Paskov K, Voss C, Haber N, Wall DP.

J Med Internet Res. 2019 May 23;21(5):e13668. doi: 10.2196/13668. Erratum in: J Med Internet Res. 2019 Jun 27;21(6):e14950.

18.

Dataset for the reporting of prostate carcinoma in radical prostatectomy specimens: updated recommendations from the International Collaboration on Cancer Reporting.

Kench JG, Judge M, Delahunt B, Humphrey PA, Kristiansen G, Oxley J, Rasiah K, Takahashi H, Trpkov K, Varma M, Wheeler TM, Zhou M, Srigley JR, Egevad L.

Virchows Arch. 2019 Sep;475(3):263-277. doi: 10.1007/s00428-019-02574-0. Epub 2019 May 16. Review.

PMID:
31098802
19.

Grading Noninvasive Bladder Cancer: World Health Organisation 1973 or 2004 May Be the Wrong Question.

Varma M, Delahunt B, van der Kwast T.

Eur Urol. 2019 Oct;76(4):413-415. doi: 10.1016/j.eururo.2019.05.001. Epub 2019 May 10.

PMID:
31080126
20.

Resistance Trend, Antibiotic Utilization and Mortality in Patients with E. coli Bacteraemia.

Najmi A, Karimi F, Kunhikatta V, Varma M, Nair S.

Open Access Maced J Med Sci. 2019 Apr 14;7(7):1119-1123. doi: 10.3889/oamjms.2019.223. eCollection 2019 Apr 15.

21.

Dataset for reporting of carcinoma of the urethra (in urethrectomy specimens): recommendations from the International Collaboration on Cancer Reporting (ICCR).

Shanks JH, Srigley JR, Brimo F, Comperat E, Delahunt B, Koch M, Lopez-Beltran A, Reuter VE, Samaratunga H, Tsuzuki T, van der Kwast T, Varma M, Grignon D.

Histopathology. 2019 Oct;75(4):453-467. doi: 10.1111/his.13877. Epub 2019 Jul 2. Review.

PMID:
31009090
22.

Percentage grade 4 tumour predicts outcome for clear cell renal cell carcinoma.

Dagher J, Delahunt B, Rioux-Leclercq N, Egevad L, Varma M, Samaratunga H.

Pathology. 2019 Jun;51(4):349-352. doi: 10.1016/j.pathol.2019.01.004. Epub 2019 Apr 12.

PMID:
30987774
23.

Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: "SLC-Phenotyping" Using Primary Human Hepatocytes.

Bi YA, Costales C, Mathialagan S, West M, Eatemadpour S, Lazzaro S, Tylaska L, Scialis R, Zhang H, Umland J, Kimoto E, Tess DA, Feng B, Tremaine LM, Varma MVS, Rodrigues AD.

J Pharmacol Exp Ther. 2019 Jul;370(1):72-83. doi: 10.1124/jpet.119.257600. Epub 2019 Apr 11.

PMID:
30975793
24.

Advanced Practice Professionals and an Outpatient Clinic: Improving Longitudinal Care in an Interventional Radiology Practice.

Crum EA, Varma MK.

Semin Intervent Radiol. 2019 Mar;36(1):13-16. doi: 10.1055/s-0039-1683357. Epub 2019 Mar 29. Review.

PMID:
30936610
25.

Interventional Radiology Private Practice Patterns.

Peck S, Van Erp J, Watabe J, Costantino M, Varma MK.

Semin Intervent Radiol. 2019 Mar;36(1):3-9. doi: 10.1055/s-0039-1683356. Epub 2019 Mar 29. Review.

PMID:
30936608
26.

Clopidogrel as a Perpetrator of Drug-Drug Interactions: A Challenge for Quantitative Predictions?

Varma MVS, Bi YA, Lazzaro S, West M.

Clin Pharmacol Ther. 2019 Jun;105(6):1295-1299. doi: 10.1002/cpt.1398. Epub 2019 Mar 30. No abstract available.

PMID:
30927478
27.

Effect of Hepatic Organic Anion-Transporting Polypeptide 1B Inhibition and Chronic Kidney Disease on the Pharmacokinetics of a Liver-Targeted Glucokinase Activator: A Model-Based Evaluation.

Bergman A, Bi YA, Mathialagan S, Litchfield J, Kazierad DJ, Pfefferkorn JA, Varma MVS.

Clin Pharmacol Ther. 2019 Oct;106(4):792-802. doi: 10.1002/cpt.1419. Epub 2019 Apr 8.

PMID:
30919935
28.

Opportunistic infection at the start of antiretroviral therapy and baseline CD4+ count less than 50 cells/mm3 are associated with poor immunological recovery.

Tilak A, Shenoy S, Varma M, Kamath A, Tripathy A, Sori R, Saravu K.

J Basic Clin Physiol Pharmacol. 2019 Mar 22;30(2):163-171. doi: 10.1515/jbcpp-2018-0105.

PMID:
30901314
29.

Coalitional Game Theory Facilitates Identification of Non-Coding Variants Associated With Autism.

Sun MW, Gupta A, Varma M, Paskov KM, Jung JY, Stockham NT, Wall DP.

Biomed Inform Insights. 2019 Mar 8;11:1178222619832859. doi: 10.1177/1178222619832859. eCollection 2019.

30.

Context-Specific Requirement of Forty-Four Two-Component Loci in Pseudomonas aeruginosa Swarming.

Kollaran AM, Joge S, Kotian HS, Badal D, Prakash D, Mishra A, Varma M, Singh V.

iScience. 2019 Mar 29;13:305-317. doi: 10.1016/j.isci.2019.02.028. Epub 2019 Mar 1.

31.

Outgroup Machine Learning Approach Identifies Single Nucleotide Variants in Noncoding DNA Associated with Autism Spectrum Disorder.

Varma M, Paskov KM, Jung JY, Sierra Chrisman B, Stockham NT, Washington PY, Wall DP.

Pac Symp Biocomput. 2019;24:260-271.

32.

Mechanistic Evaluation of the Complex Drug-Drug Interactions of Maraviroc: Contribution of Cytochrome P450 3A, P-Glycoprotein and Organic Anion Transporting Polypeptide 1B1.

Kimoto E, Vourvahis M, Scialis RJ, Eng H, Rodrigues AD, Varma MVS.

Drug Metab Dispos. 2019 May;47(5):493-503. doi: 10.1124/dmd.118.085241. Epub 2019 Mar 12.

PMID:
30862625
33.

Reversible defect engineering in graphene grain boundaries.

Balasubramanian K, Biswas T, Ghosh P, Suran S, Mishra A, Mishra R, Sachan R, Jain M, Varma M, Pratap R, Raghavan S.

Nat Commun. 2019 Mar 6;10(1):1090. doi: 10.1038/s41467-019-09000-8.

34.

Intraductal carcinoma of the prostate: a critical re-appraisal.

Varma M, Delahunt B, Egevad L, Samaratunga H, Kristiansen G.

Virchows Arch. 2019 May;474(5):525-534. doi: 10.1007/s00428-019-02544-6. Epub 2019 Mar 1. Review.

35.

Posterior reversible encephalopathy syndrome due to hypercalcaemia: a rare cause.

Bolanthakodi N, Vidyasagar S, Varma M, Holla A.

BMJ Case Rep. 2019 Feb 11;12(2). pii: bcr-2017-223415. doi: 10.1136/bcr-2017-223415.

PMID:
30755423
36.

Disseminated Nocardia asiatica infection in an immunocompromised individual: A rare entity needs careful vigilance.

Banerjee B, Gupta R, Varma M, Mukhopadhyay C, Shaw T.

J Infect Public Health. 2019 Mar - Apr;12(2):167-170. doi: 10.1016/j.jiph.2018.12.008. Epub 2019 Jan 28. Review.

37.

Should we rename low risk cancers?

Esserman LJ, Varma M.

BMJ. 2019 Jan 23;364:k4699. doi: 10.1136/bmj.k4699. No abstract available.

PMID:
30674473
38.

Ionic Pyridinium-Oxazole Dyads: Design, Synthesis, and Application in Mitochondrial Imaging.

Shaikh AC, Varma ME, Mule RD, Banerjee S, Kulkarni PP, Patil NT.

J Org Chem. 2019 Feb 15;84(4):1766-1777. doi: 10.1021/acs.joc.8b02528. Epub 2019 Jan 29.

PMID:
30638382
39.

Handling and reporting of pelvic lymphadenectomy specimens in prostate and bladder cancer: a web-based survey by the European Network of Uropathology.

Prendeville S, Berney DM, Bubendorf L, Compérat E, Egevad L, Hes O, Kristiansen G, Oxley J, van Leenders GJLH, Varma M, van der Kwast T.

Histopathology. 2019 May;74(6):844-852. doi: 10.1111/his.13818. Epub 2019 Apr 1.

PMID:
30604878
40.

Dataset for the reporting of prostate carcinoma in core needle biopsy and transurethral resection and enucleation specimens: recommendations from the International Collaboration on Cancer Reporting (ICCR).

Egevad L, Judge M, Delahunt B, Humphrey PA, Kristiansen G, Oxley J, Rasiah K, Takahashi H, Trpkov K, Varma M, Wheeler TM, Zhou M, Srigley JR, Kench JG.

Pathology. 2019 Jan;51(1):11-20. doi: 10.1016/j.pathol.2018.10.003. Epub 2018 Nov 23.

PMID:
30477882
41.

Murine Norovirus Infection Induces TH1 Inflammatory Responses to Dietary Antigens.

Bouziat R, Biering SB, Kouame E, Sangani KA, Kang S, Ernest JD, Varma M, Brown JJ, Urbanek K, Dermody TS, Ng A, Hinterleitner R, Hwang S, Jabri B.

Cell Host Microbe. 2018 Nov 14;24(5):677-688.e5. doi: 10.1016/j.chom.2018.10.004. Epub 2018 Nov 1.

PMID:
30392830
42.

Invasive nontyphoidal Salmonella disease in southern India: a 5-year experience from a tertiary care hospital

Patra S, Mukim Y, Varma M, Mukhopadhyay C, Kalwaje Eshwara V.

Turk J Med Sci. 2018 Oct 31;48(5):1030-1035. doi: 10.3906/sag-1804-90.

PMID:
30384571
43.

Antigen discovery and specification of immunodominance hierarchies for MHCII-restricted epitopes.

Graham DB, Luo C, O'Connell DJ, Lefkovith A, Brown EM, Yassour M, Varma M, Abelin JG, Conway KL, Jasso GJ, Matar CG, Carr SA, Xavier RJ.

Nat Med. 2018 Nov;24(11):1762-1772. doi: 10.1038/s41591-018-0203-7. Epub 2018 Oct 22.

44.

TNM clinical staging of prostate cancer: issues and solutions.

Varma M, Cochlin D, Delahunt B, Kynaston H, Rees J, Rous B, Narahari K.

BJU Int. 2019 Mar;123(3):382-384. doi: 10.1111/bju.14589. Epub 2018 Oct 31. No abstract available.

PMID:
30315677
45.

Low risk cancer: recalibrate rather than just rename?

Varma M.

BMJ. 2018 Oct 9;363:k4211. doi: 10.1136/bmj.k4211. No abstract available.

PMID:
30301723
46.

Gleason Grading: There Is No Substitute for Judgment.

Varma M.

Am J Surg Pathol. 2019 Feb;43(2):290-291. doi: 10.1097/PAS.0000000000001175. No abstract available.

PMID:
30300147
47.

Assessment of Pyrexia and Associated Sickness Behavior in Patients with Chronic Periodontitis.

Pal M, Kumar S, Varma M, Gopalkrishna P, Bhat S.

Neuroimmunomodulation. 2018;25(3):138-145. doi: 10.1159/000492471. Epub 2018 Sep 10.

PMID:
30199858
48.

Consolidation mFOLFOX6 Chemotherapy After Chemoradiotherapy Improves Survival in Patients With Locally Advanced Rectal Cancer: Final Results of a Multicenter Phase II Trial.

Marco MR, Zhou L, Patil S, Marcet JE, Varma MG, Oommen S, Cataldo PA, Hunt SR, Kumar A, Herzig DO, Fichera A, Polite BN, Hyman NH, Ternent CA, Stamos MJ, Pigazzi A, Dietz D, Yakunina Y, Pelossof R, Garcia-Aguilar J; Timing of Rectal Cancer Response to Chemoradiation Consortium.

Dis Colon Rectum. 2018 Oct;61(10):1146-1155. doi: 10.1097/DCR.0000000000001207.

49.

Scalable Nanogap Sensors for Non-Redox Enzyme Assays.

Su X, Tayebi N, Credo GM, Wu K, Elibol OH, Liu DJ, Daniels JS, Li H, Hall DA, Varma M.

ACS Sens. 2018 Sep 28;3(9):1773-1781. doi: 10.1021/acssensors.8b00500. Epub 2018 Sep 11.

PMID:
30156096
50.

ABC transportome inventory of human pathogenic yeast Candida glabrata: Phylogenetic and expression analysis.

Kumari S, Kumar M, Khandelwal NK, Kumari P, Varma M, Vishwakarma P, Shahi G, Sharma S, Lynn AM, Prasad R, Gaur NA.

PLoS One. 2018 Aug 28;13(8):e0202993. doi: 10.1371/journal.pone.0202993. eCollection 2018.

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