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Development of novel economical methodologies for zymographic analysis of purified xylano-pectinolytic enzymes using agrowaste based substrates.

Agrawal S, Kaur A, Varghese LM, Mahajan R.

Biotechnol Prog. 2019 Sep 18:e2913. doi: 10.1002/btpr.2913. [Epub ahead of print]


Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Labuhn M, Perkins K, Matzk S, Varghese L, Garnett C, Papaemmanuil E, Metzner M, Kennedy A, Amstislavskiy V, Risch T, Bhayadia R, Samulowski D, Hernandez DC, Stoilova B, Iotchkova V, Oppermann U, Scheer C, Yoshida K, Schwarzer A, Taub JW, Crispino JD, Weiss MJ, Hayashi Y, Taga T, Ito E, Ogawa S, Reinhardt D, Yaspo ML, Campbell PJ, Roberts I, Constantinescu SN, Vyas P, Heckl D, Klusmann JH.

Cancer Cell. 2019 Sep 16;36(3):340. doi: 10.1016/j.ccell.2019.08.014. No abstract available.


Fast flow rate processes for purification of alkaline xylanase isoforms from Bacillus pumilus AJK and their biochemical characterization for industrial application purposes.

Singh A, Sharma D, Varghese LM, Mahajan R.

Biotechnol Prog. 2019 Aug 30:e2898. doi: 10.1002/btpr.2898. [Epub ahead of print]


Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Labuhn M, Perkins K, Matzk S, Varghese L, Garnett C, Papaemmanuil E, Metzner M, Kennedy A, Amstislavskiy V, Risch T, Bhayadia R, Samulowski D, Hernandez DC, Stoilova B, Iotchkova V, Oppermann U, Scheer C, Yoshida K, Schwarzer A, Taub JW, Crispino JD, Weiss MJ, Hayashi Y, Taga T, Ito E, Ogawa S, Reinhardt D, Yaspo ML, Campbell PJ, Roberts I, Constantinescu SN, Vyas P, Heckl D, Klusmann JH.

Cancer Cell. 2019 Aug 12;36(2):123-138.e10. doi: 10.1016/j.ccell.2019.06.007. Epub 2019 Jul 11. Erratum in: Cancer Cell. 2019 Sep 16;36(3):340.


Public Health Impact and Cost-Effectiveness of Non-live Adjuvanted Recombinant Zoster Vaccine in Canadian Adults.

McGirr A, Van Oorschot D, Widenmaier R, Stokes M, Ganz ML, Jung H, Varghese L, Curran D.

Appl Health Econ Health Policy. 2019 Oct;17(5):723-732. doi: 10.1007/s40258-019-00491-6.


A novel and cost-effective methodology for enhanced production of industrially valuable alkaline xylano-pectinolytic enzymes cocktail in short solid-state fermentation cycle.

Agrawal S, Varghese LM, Mahajan R.

Biotechnol Prog. 2019 Jun 19:e2872. doi: 10.1002/btpr.2872. [Epub ahead of print]


The role of the thrombopoietin receptor MPL in myeloproliferative neoplasms: recent findings and potential therapeutic applications.

Vainchenker W, Plo I, Marty C, Varghese LN, Constantinescu SN.

Expert Rev Hematol. 2019 Jun;12(6):437-448. doi: 10.1080/17474086.2019.1617129. Epub 2019 May 22.


Simultaneous production of industrially important alkaline xylanase-pectinase enzymes by a bacterium at low cost under solid-state fermentation conditions.

Kaur A, Varghese LM, Mahajan R.

Biotechnol Appl Biochem. 2019 Jul;66(4):574-585. doi: 10.1002/bab.1757. Epub 2019 May 7.


Comment on: 'Clinical and Economic Impact of a Potential Switch from 13-Valent to 10-Valent Pneumococcal Conjugate Infant Vaccination in Canada', Wilson et al., 22 June 2018.

McGirr A, Iqbal SM, Olbrecht J, Varghese L.

Infect Dis Ther. 2018 Dec;7(4):535-538. doi: 10.1007/s40121-018-0220-3. Epub 2018 Nov 8. No abstract available.


Cost Effectiveness of Quadrivalent Influenza Vaccines Compared with Trivalent Influenza Vaccines in Young Children and Older Adults in Korea.

Kim YK, Song JY, Jang H, Kim TH, Koo H, Varghese L, Han E.

Pharmacoeconomics. 2018 Dec;36(12):1475-1490. doi: 10.1007/s40273-018-0715-5.


Cost-effectiveness of the recombinant zoster vaccine in the German population aged ≥60 years old.

Van Oorschot D, Anastassopoulou A, Poulsen Nautrup B, Varghese L, von Krempelhuber A, Neine M, Lorenc S, Curran D.

Hum Vaccin Immunother. 2019;15(1):34-44. doi: 10.1080/21645515.2018.1509645. Epub 2018 Sep 6.


Sinonasal organising haematoma - a little known entity.

Varghese L, Mukhopadhyay S, Mehan R, Kurien R, Thomas M, Rupa V.

Braz J Otorhinolaryngol. 2018 Jul 17. pii: S1808-8694(18)30428-2. doi: 10.1016/j.bjorl.2018.05.013. [Epub ahead of print]


Cost-effectiveness of an Adjuvanted Recombinant Zoster Vaccine in older adults in the United States.

Curran D, Patterson B, Varghese L, Van Oorschot D, Buck P, Carrico J, Hicks K, Lee B, Yawn B.

Vaccine. 2018 Aug 9;36(33):5037-5045. doi: 10.1016/j.vaccine.2018.07.005. Epub 2018 Jul 14.


Identifying factors that influence the '6-hour target' in the Emergency Department by applying Regression Analysis.

Borhan F, Borhan N, Ahmed S, Varghese L, O'Connor E.

Ir Med J. 2018 Feb 9;111(2):699.


Deep head and neck infections: outcome following empirical therapy with early generation antibiotics.

Varghese L, Mathews SS, Antony Jude Prakash J, Rupa V.

Trop Doct. 2018 Jul;48(3):179-182. doi: 10.1177/0049475518774472. Epub 2018 May 14.


The Potential Public Health Impact of Herpes Zoster Vaccination of People Aged ≥ 50 Years in Japan: Results of a Markov Model Analysis.

Watanabe D, Mizukami A, Holl K, Curran D, Van Oorschot D, Varghese L, Shiragami M.

Dermatol Ther (Heidelb). 2018 Jun;8(2):269-284. doi: 10.1007/s13555-018-0236-3. Epub 2018 Apr 21.


Retraction notice to: Sensitization of squamous cell carcinoma to cisplatin induced killing by natural agents.

Ali S, Varghese L, Pereira L, Tulunay-Ugur OE, Kucuk O, Carey TE, Wolf GT, Sarkar FH.

Cancer Lett. 2018 Jun 1;423:154. doi: 10.1016/j.canlet.2018.03.018.


Cooperative and FRET-Assisted Brightness Enhancement in Oligo(phenylene ethynylene): Quantum Dot Organic-Inorganic Nanohybrids.

Gopi A, Sajitha M, Haridas R, Varghese L, Yoosaf K.

Chem Asian J. 2018 Jun 4;13(11):1492-1499. doi: 10.1002/asia.201800328. Epub 2018 May 9.


A dairy worker with fever and an abnormal echocardiogram.

Ghosh GC, Varghese L, Thomson VS.

Heart Asia. 2017 Jul 11;9(2):e010915. doi: 10.1136/heartasia-2017-010915. eCollection 2017.


Radiation dose from percutaneous transluminal coronary angioplasty procedure performed using a flat detector for different clinical angiographic projections.

Varghese A, Livingstone RS, Varghese L, Dey S, Jose J, Thomson VS, George OK, George PV.

J Radiol Prot. 2018 Jun;38(2):511-524. doi: 10.1088/1361-6498/aaab71. Epub 2018 Jan 30.


Treatment of Advanced Carcinoma of the Larynx and Hypopharynx with Laser Followed by External Radiotherapy.

Varghese L, Mathew J, John S, Job A.

Iran J Otorhinolaryngol. 2017 Sep;29(94):247-253.


Assessment of the potential public health impact of Herpes Zoster vaccination in Germany.

Curran D, Van Oorschot D, Varghese L, Oostvogels L, Mrkvan T, Colindres R, von Krempelhuber A, Anastassopoulou A.

Hum Vaccin Immunother. 2017 Oct 3;13(10):2213-2221. doi: 10.1080/21645515.2017.1345399. Epub 2017 Jul 14.


A Statistical Methodology to determine factors affecting Patient Experience Time Targets in the Emergency Department.

Borhan F, Ahmed S, Varghese L, O'Connor E.

Ir Med J. 2017 Jan 11;110(1):506. No abstract available.


Cost-effective screening and isolation of xylano-cellulolytic positive microbes from termite gut and termitarium.

Varghese LM, Agrawal S, Sharma D, Mandhan RP, Mahajan R.

3 Biotech. 2017 Jun;7(2):108. doi: 10.1007/s13205-017-0733-6. Epub 2017 May 31.


Epidemiology and Clinical Features of Human Coronaviruses in the Pediatric Population.

Varghese L, Zachariah P, Vargas C, LaRussa P, Demmer RT, Furuya YE, Whittier S, Reed C, Stockwell MS, Saiman L.

J Pediatric Infect Dis Soc. 2018 May 15;7(2):151-158. doi: 10.1093/jpids/pix027.


Bi-directional audiovisual influences on temporal modulation discrimination.

Varghese L, Mathias SR, Bensussen S, Chou K, Goldberg HR, Sun Y, Sekuler R, Shinn-Cunningham BG.

J Acoust Soc Am. 2017 Apr;141(4):2474. doi: 10.1121/1.4979470.


The Thrombopoietin Receptor: Structural Basis of Traffic and Activation by Ligand, Mutations, Agonists, and Mutated Calreticulin.

Varghese LN, Defour JP, Pecquet C, Constantinescu SN.

Front Endocrinol (Lausanne). 2017 Mar 31;8:59. doi: 10.3389/fendo.2017.00059. eCollection 2017. Review.


The temporal impact of aging on the burden of herpes zoster.

Varghese L, Standaert B, Olivieri A, Curran D.

BMC Geriatr. 2017 Jan 23;17(1):30. doi: 10.1186/s12877-017-0420-9.


Contraindication of live vaccines in immunocompromised patients: an estimate of the number of affected people in the USA and the UK.

Varghese L, Curran D, Bunge E, Vroling H, van Kessel F, Guignard A, Casabona G, Olivieri A.

Public Health. 2017 Jan;142:46-49. doi: 10.1016/j.puhe.2016.10.013. Epub 2016 Nov 18. No abstract available.


An incomplete trafficking defect to the cell-surface leads to paradoxical thrombocytosis for human and murine MPL P106L.

Favale F, Messaoudi K, Varghese LN, Boukour S, Pecquet C, Gryshkova V, Defour JP, Albu RI, Bluteau O, Ballerini P, Leverger G, Plo I, Debili N, Raslova H, Favier R, Constantinescu SN, Vainchenker W.

Blood. 2016 Dec 29;128(26):3146-3158. doi: 10.1182/blood-2016-06-722058. Epub 2016 Nov 10.


Response to Wu et al. - Cost-effectiveness analysis of infant pneumococcal vaccination in Malaysia and Hong Kong.

Varghese L, Mungall B, Zhang XH, Hoet B.

Hum Vaccin Immunother. 2016 Oct 2;12(10):2675-2680. doi: 10.1080/21645515.2016.1192738. Epub 2016 Jul 26.


Posaconazole: an emerging therapeutic option for invasive rhino-orbito-cerebral mucormycosis.

Manesh A, John AO, Mathew B, Varghese L, Rupa V, Zachariah A, Varghese GM.

Mycoses. 2016 Dec;59(12):765-772. doi: 10.1111/myc.12529. Epub 2016 Jul 22.


Radiation doses and estimated risk from angiographic projections during coronary angiography performed using novel flat detector.

Varghese A, Livingstone RS, Varghese L, Kumar P, Srinath SC, George OK, George PV.

J Appl Clin Med Phys. 2016 May 8;17(3):433-441. doi: 10.1120/jacmp.v17i3.5926.


Elusive treatment for human rhinosporidiosis.

Janardhanan J, Patole S, Varghese L, Rupa V, Tirkey AJ, Varghese GM.

Int J Infect Dis. 2016 Jul;48:3-4. doi: 10.1016/j.ijid.2016.04.013. Epub 2016 Apr 21.


Dysregulation of Norepinephrine Release in the Absence of Functional Synaptotagmin 7.

Shih AM, Varghese L, Bittar A, Park SH, Chung JM, Shin OH.

J Cell Biochem. 2016 Jun;117(6):1446-53. doi: 10.1002/jcb.25436. Epub 2015 Nov 30.


Integrated analysis of oral tongue squamous cell carcinoma identifies key variants and pathways linked to risk habits, HPV, clinical parameters and tumor recurrence.

Krishnan N, Gupta S, Palve V, Varghese L, Pattnaik S, Jain P, Khyriem C, Hariharan A, Dhas K, Nair J, Pareek M, Prasad V, Siddappa G, Suresh A, Kekatpure V, Kuriakose M, Panda B.

F1000Res. 2015 Nov 5;4:1215. doi: 10.12688/f1000research.7302.1. eCollection 2015.


Nasal Angioleiomyoma: An Unusual Cause of Epistaxis.

Varghese L, Mathew S, Vijayakumar K.

Oman Med J. 2015 Jul;30(4):303-5. doi: 10.5001/omj.2015.60.


Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop.

Tanzer MC, Tripaydonis A, Webb AI, Young SN, Varghese LN, Hall C, Alexander WS, Hildebrand JM, Silke J, Murphy JM.

Biochem J. 2015 Oct 15;471(2):255-65. doi: 10.1042/BJ20150678. Epub 2015 Aug 17.


Evidence against attentional state modulating scalp-recorded auditory brainstem steady-state responses.

Varghese L, Bharadwaj HM, Shinn-Cunningham BG.

Brain Res. 2015 Nov 11;1626:146-64. doi: 10.1016/j.brainres.2015.06.038. Epub 2015 Jul 14. Review.


Vitamin D deficiency in postmenopausal women with pelvic floor disorders.

Navaneethan PR, Kekre A, Jacob KS, Varghese L.

J Midlife Health. 2015 Apr-Jun;6(2):66-9. doi: 10.4103/0976-7800.158948.


Bowel vaginoplasty in children and young women: an institutional experience with 55 patients.

Kisku S, Varghese L, Kekre A, Sen S, Karl S, Mathai J, Thomas RJ, Kishore R.

Int Urogynecol J. 2015 Oct;26(10):1441-8. doi: 10.1007/s00192-015-2728-3. Epub 2015 May 12.


Clinical effectiveness of a sedation protocol minimizing benzodiazepine infusions and favoring early dexmedetomidine: a before-after study.

Skrupky LP, Drewry AM, Wessman B, Field RR, Fagley RE, Varghese L, Lieu A, Olatunde J, Micek ST, Kollef MH, Boyle WA.

Crit Care. 2015 Apr 2;19:136. doi: 10.1186/s13054-015-0874-0.


Nasal conidiobolomycosis: a successful treatment option for localized disease.

Cherian LM, Varghese L, Panchatcharam BS, Parmar HV, Varghese GM.

J Postgrad Med. 2015 Apr-Jun;61(2):143-4. doi: 10.4103/0022-3859.153112. No abstract available.


Symptoms, prevalence, and risk factors of overactive bladder in women in south India.

Selvaraj J, Kekre AN, Varghese L, Jacob KS.

Int J Gynaecol Obstet. 2015 Jun;129(3):274-5. doi: 10.1016/j.ijgo.2014.12.006. Epub 2015 Feb 24. No abstract available.


Septic arthritis of the temporomandibular joint caused by Aspergillus flavus infection as a complication of otitis externa.

Varghese L, Chacko R, Varghese GM, Job A.

Ear Nose Throat J. 2015 Mar;94(3):E24-6.


Pentraxin 3 mediates neurogenesis and angiogenesis after cerebral ischaemia.

Rodriguez-Grande B, Varghese L, Molina-Holgado F, Rajkovic O, Garlanda C, Denes A, Pinteaux E.

J Neuroinflammation. 2015 Jan 24;12:15. doi: 10.1186/s12974-014-0227-y.


Reconfigurable radio-frequency arbitrary waveforms synthesized in a silicon photonic chip.

Wang J, Shen H, Fan L, Wu R, Niu B, Varghese LT, Xuan Y, Leaird DE, Wang X, Gan F, Weiner AM, Qi M.

Nat Commun. 2015 Jan 12;6:5957. doi: 10.1038/ncomms6957.


Comparison of steady-state visual and somatosensory evoked potentials for brain-computer interface control.

Smith DJ, Varghese LA, Stepp CE, Guenther FH.

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:1234-7. doi: 10.1109/EMBC.2014.6943820.


Bandwidth scaling of a phase-modulated continuous-wave comb through four-wave mixing in a silicon nano-waveguide.

Liu Y, Metcalf AJ, Company VT, Wu R, Fan L, Varghese LT, Qi M, Weiner AM.

Opt Lett. 2014 Nov 15;39(22):6478-81. doi: 10.1364/OL.39.006478.


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