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Items: 1 to 50 of 63

1.

Validation of a drooling questionnaire in Indian children with cerebral palsy.

Job A, Naina P, Syed KA, Thomas M, John M, Varghese AM.

Int J Pediatr Otorhinolaryngol. 2018 Sep;112:55-60. doi: 10.1016/j.ijporl.2018.06.029. Epub 2018 Jun 19.

PMID:
30055740
2.

Nanoliposomal irinotecan with fluorouracil for the treatment of advanced pancreatic cancer, a single institution experience.

Glassman DC, Palmaira RL, Covington CM, Desai AM, Ku GY, Li J, Harding JJ, Varghese AM, O'Reilly EM, Yu KH.

BMC Cancer. 2018 Jun 27;18(1):693. doi: 10.1186/s12885-018-4605-1.

3.

Allergic Rhinitis in Relation to Food Allergies: Pointers to future research.

Al-Abri R, Al-Amri AS, Al-Dhahli Z, Varghese AM.

Sultan Qaboos Univ Med J. 2018 Feb;18(1):e30-e33. doi: 10.18295/squmj.2018.18.01.005. Epub 2018 Apr 4.

4.

Clinical Study on Middle Ear Diseases in Children with Orofacial Clefts.

Kalaiarasi R, Syed KA, Vijayakumar C, Varghese AM, John M.

Cureus. 2018 Feb 8;10(2):e2175. doi: 10.7759/cureus.2175.

5.

A First-in-Human Phase 1 Study of LY3023414, an Oral PI3K/mTOR Dual Inhibitor, in Patients with Advanced Cancer.

Bendell JC, Varghese AM, Hyman DM, Bauer TM, Pant S, Callies S, Lin J, Martinez R, Wickremsinhe E, Fink A, Wacheck V, Moore KN.

Clin Cancer Res. 2018 Jul 15;24(14):3253-3262. doi: 10.1158/1078-0432.CCR-17-3421. Epub 2018 Apr 10.

PMID:
29636360
6.

Capillary leak syndrome in Daboia russelii bite-a complication associated with poor outcome.

Kendre PP, Jose MP, Varghese AM, Menon JC, Joseph JK.

Trans R Soc Trop Med Hyg. 2018 Feb 1;112(2):88-93. doi: 10.1093/trstmh/try026.

PMID:
29584906
7.

Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms.

Lowery MA, Wong W, Jordan EJ, Lee JW, Kemel Y, Vijai J, Mandelker D, Zehir A, Capanu M, Salo-Mullen E, Arnold AG, Yu KH, Varghese AM, Kelsen DP, Brenner R, Kaufmann E, Ravichandran V, Mukherjee S, Berger MF, Hyman DM, Klimstra DS, Abou-Alfa GK, Tjan C, Covington C, Maynard H, Allen PJ, Askan G, Leach SD, Iacobuzio-Donahue CA, Robson ME, Offit K, Stadler ZK, O'Reilly EM.

J Natl Cancer Inst. 2018 Feb 28. doi: 10.1093/jnci/djy024. [Epub ahead of print]

PMID:
29506128
8.

Radiological Evaluation of Cochlear Orientation and Its Implications in Cochlear Implantation.

Kiran AS, Varghese AM, Irodi A, Lepcha A, Mathew J, Jeyaseelan V.

Indian J Otolaryngol Head Neck Surg. 2018 Mar;70(1):1-9. doi: 10.1007/s12070-017-1173-7. Epub 2017 Jul 24.

PMID:
29456935
9.

Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations.

Hu ZI, Shia J, Stadler ZK, Varghese AM, Capanu M, Salo-Mullen E, Lowery MA, Diaz LA Jr, Mandelker D, Yu KH, Zervoudakis A, Kelsen DP, Iacobuzio-Donahue CA, Klimstra DS, Saltz LB, Sahin IH, O'Reilly EM.

Clin Cancer Res. 2018 Mar 15;24(6):1326-1336. doi: 10.1158/1078-0432.CCR-17-3099. Epub 2018 Jan 24.

PMID:
29367431
10.

Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.

Yaeger R, Chatila WK, Lipsyc MD, Hechtman JF, Cercek A, Sanchez-Vega F, Jayakumaran G, Middha S, Zehir A, Donoghue MTA, You D, Viale A, Kemeny N, Segal NH, Stadler ZK, Varghese AM, Kundra R, Gao J, Syed A, Hyman DM, Vakiani E, Rosen N, Taylor BS, Ladanyi M, Berger MF, Solit DB, Shia J, Saltz L, Schultz N.

Cancer Cell. 2018 Jan 8;33(1):125-136.e3. doi: 10.1016/j.ccell.2017.12.004.

PMID:
29316426
11.

First-in-Class ERK1/2 Inhibitor Ulixertinib (BVD-523) in Patients with MAPK Mutant Advanced Solid Tumors: Results of a Phase I Dose-Escalation and Expansion Study.

Sullivan RJ, Infante JR, Janku F, Wong DJL, Sosman JA, Keedy V, Patel MR, Shapiro GI, Mier JW, Tolcher AW, Wang-Gillam A, Sznol M, Flaherty K, Buchbinder E, Carvajal RD, Varghese AM, Lacouture ME, Ribas A, Patel SP, DeCrescenzo GA, Emery CM, Groover AL, Saha S, Varterasian M, Welsch DJ, Hyman DM, Li BT.

Cancer Discov. 2018 Feb;8(2):184-195. doi: 10.1158/2159-8290.CD-17-1119. Epub 2017 Dec 15.

PMID:
29247021
12.

Chimeric antigen receptor (CAR) T and other T cell strategies for pancreas adenocarcinoma.

Varghese AM.

Chin Clin Oncol. 2017 Dec;6(6):66. doi: 10.21037/cco.2017.09.04. Epub 2017 Oct 24.

13.

Clinical and molecular characterization of patients with cancer of unknown primary in the modern era.

Varghese AM, Arora A, Capanu M, Camacho N, Won HH, Zehir A, Gao J, Chakravarty D, Schultz N, Klimstra DS, Ladanyi M, Hyman DM, Solit DB, Berger MF, Saltz LB.

Ann Oncol. 2017 Dec 1;28(12):3015-3021. doi: 10.1093/annonc/mdx545.

PMID:
29045506
14.

It is Always Darkest Before Dawn.

Al Balushi M, Varghese AM, Al Azri F, Al Abri R.

Oman Med J. 2017 Sep;32(5):440-441. doi: 10.5001/omj.2017.83. No abstract available.

15.

Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Zehir A, Benayed R, Shah RH, Syed A, Middha S, Kim HR, Srinivasan P, Gao J, Chakravarty D, Devlin SM, Hellmann MD, Barron DA, Schram AM, Hameed M, Dogan S, Ross DS, Hechtman JF, DeLair DF, Yao J, Mandelker DL, Cheng DT, Chandramohan R, Mohanty AS, Ptashkin RN, Jayakumaran G, Prasad M, Syed MH, Rema AB, Liu ZY, Nafa K, Borsu L, Sadowska J, Casanova J, Bacares R, Kiecka IJ, Razumova A, Son JB, Stewart L, Baldi T, Mullaney KA, Al-Ahmadie H, Vakiani E, Abeshouse AA, Penson AV, Jonsson P, Camacho N, Chang MT, Won HH, Gross BE, Kundra R, Heins ZJ, Chen HW, Phillips S, Zhang H, Wang J, Ochoa A, Wills J, Eubank M, Thomas SB, Gardos SM, Reales DN, Galle J, Durany R, Cambria R, Abida W, Cercek A, Feldman DR, Gounder MM, Hakimi AA, Harding JJ, Iyer G, Janjigian YY, Jordan EJ, Kelly CM, Lowery MA, Morris LGT, Omuro AM, Raj N, Razavi P, Shoushtari AN, Shukla N, Soumerai TE, Varghese AM, Yaeger R, Coleman J, Bochner B, Riely GJ, Saltz LB, Scher HI, Sabbatini PJ, Robson ME, Klimstra DS, Taylor BS, Baselga J, Schultz N, Hyman DM, Arcila ME, Solit DB, Ladanyi M, Berger MF.

Nat Med. 2017 Aug 4;23(8):1004. doi: 10.1038/nm0817-1004c. No abstract available.

PMID:
28777785
16.

Highly selective SYK inhibitor, GSK143, abrogates survival signals in chronic lymphocytic leukaemia.

Varghese AM, Rawstron A, Newton D, Tooze RM, Munir T, Dickson M, Doody GM, Hillmen P.

Br J Haematol. 2018 Sep;182(6):927-930. doi: 10.1111/bjh.14884. Epub 2017 Aug 2. No abstract available.

PMID:
28770560
17.

Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype.

Lowery MA, Jordan EJ, Basturk O, Ptashkin RN, Zehir A, Berger MF, Leach T, Herbst B, Askan G, Maynard H, Glassman D, Covington C, Schultz N, Abou-Alfa GK, Harding JJ, Klimstra DS, Hechtman JF, Hyman DM, Allen PJ, Jarnagin WR, Balachandran VP, Varghese AM, Schattner MA, Yu KH, Saltz LB, Solit DB, Iacobuzio-Donahue CA, Leach SD, O'Reilly EM.

Clin Cancer Res. 2017 Oct 15;23(20):6094-6100. doi: 10.1158/1078-0432.CCR-17-0899. Epub 2017 Jul 28.

PMID:
28754816
18.

Congenital Vallecular Cyst: ARare and Potentially Lethal Condition.

Mallick SA, Qureshi TN, Varghese AM, Busaidi MMA.

J Coll Physicians Surg Pak. 2017 Jun;27(6):376-377. doi: 2641.

PMID:
28689530
19.

Is this the Right Direction for Dengue Fever Research in India?

Daniel SM, Varghese AM.

J Assoc Physicians India. 2017 May;65(5):110. No abstract available.

PMID:
28598067
20.

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Zehir A, Benayed R, Shah RH, Syed A, Middha S, Kim HR, Srinivasan P, Gao J, Chakravarty D, Devlin SM, Hellmann MD, Barron DA, Schram AM, Hameed M, Dogan S, Ross DS, Hechtman JF, DeLair DF, Yao J, Mandelker DL, Cheng DT, Chandramohan R, Mohanty AS, Ptashkin RN, Jayakumaran G, Prasad M, Syed MH, Rema AB, Liu ZY, Nafa K, Borsu L, Sadowska J, Casanova J, Bacares R, Kiecka IJ, Razumova A, Son JB, Stewart L, Baldi T, Mullaney KA, Al-Ahmadie H, Vakiani E, Abeshouse AA, Penson AV, Jonsson P, Camacho N, Chang MT, Won HH, Gross BE, Kundra R, Heins ZJ, Chen HW, Phillips S, Zhang H, Wang J, Ochoa A, Wills J, Eubank M, Thomas SB, Gardos SM, Reales DN, Galle J, Durany R, Cambria R, Abida W, Cercek A, Feldman DR, Gounder MM, Hakimi AA, Harding JJ, Iyer G, Janjigian YY, Jordan EJ, Kelly CM, Lowery MA, Morris LGT, Omuro AM, Raj N, Razavi P, Shoushtari AN, Shukla N, Soumerai TE, Varghese AM, Yaeger R, Coleman J, Bochner B, Riely GJ, Saltz LB, Scher HI, Sabbatini PJ, Robson ME, Klimstra DS, Taylor BS, Baselga J, Schultz N, Hyman DM, Arcila ME, Solit DB, Ladanyi M, Berger MF.

Nat Med. 2017 Jun;23(6):703-713. doi: 10.1038/nm.4333. Epub 2017 May 8. Erratum in: Nat Med. 2017 Aug 4;23 (8):1004.

21.

CAR T-cell therapy for pancreatic cancer.

DeSelm CJ, Tano ZE, Varghese AM, Adusumilli PS.

J Surg Oncol. 2017 Jul;116(1):63-74. doi: 10.1002/jso.24627. Epub 2017 Mar 27. Review.

22.

Eradication of minimal residual disease improves overall and progression-free survival in patients with chronic lymphocytic leukaemia, evidence from NCRN CLL207: a phase II trial assessing alemtuzumab consolidation.

Varghese AM, Howard DR, Pocock C, Rawstron AC, Follows G, McCarthy H, Dearden C, Fegan C, Milligan D, Smith AF, Gregory W, Hillmen P; NCRI CLL Sub-Group.

Br J Haematol. 2017 Feb;176(4):573-582. doi: 10.1111/bjh.14342. Epub 2016 Dec 29.

23.

Brain-Derived Neurotrophic Factor Facilitates Functional Recovery from ALS-Cerebral Spinal Fluid-Induced Neurodegenerative Changes in the NSC-34 Motor Neuron Cell Line.

Shruthi S, Sumitha R, Varghese AM, Ashok S, Chandrasekhar Sagar BK, Sathyaprabha TN, Nalini A, Kramer BW, Raju TR, Vijayalakshmi K, Alladi PA.

Neurodegener Dis. 2017;17(1):44-58. Epub 2016 Sep 13.

PMID:
27617773
24.

Endoscopic Repair of CSF Fistulae: A Ten Year Experience.

Alexander A, Mathew J, Varghese AM, Ganesan S.

J Clin Diagn Res. 2016 Aug;10(8):MC01-4. doi: 10.7860/JCDR/2016/18903.8390. Epub 2016 Aug 1.

25.

Current management and future directions in metastatic pancreatic adenocarcinoma.

Varghese AM, Lowery MA, Yu KH, O'Reilly EM.

Cancer. 2016 Dec 15;122(24):3765-3775. doi: 10.1002/cncr.30342. Epub 2016 Sep 20. Review.

26.

A phase I trial of the Hedgehog inhibitor, sonidegib (LDE225), in combination with etoposide and cisplatin for the initial treatment of extensive stage small cell lung cancer.

Pietanza MC, Litvak AM, Varghese AM, Krug LM, Fleisher M, Teitcher JB, Holodny AI, Sima CS, Woo KM, Ng KK, Won HH, Berger MF, Kris MG, Rudin CM.

Lung Cancer. 2016 Sep;99:23-30. doi: 10.1016/j.lungcan.2016.04.014. Epub 2016 Apr 26.

27.

Congenital midnasal stenosis - A novel technique for management.

Syed KA, Raja K, Kolethekkat AA, Varghese AM, Al Abri R, Kurien M.

Int J Pediatr Otorhinolaryngol. 2016 Aug;87:117-20. doi: 10.1016/j.ijporl.2016.06.014. Epub 2016 Jun 7.

PMID:
27368456
28.

"Post intubation Laryngeal injuries in a pediatric intensive care unit of tertiary hospital in India: A Fibreoptic endoscopic study".

Bharti B, Syed KA, Ebenezer K, Varghese AM, Kurien M.

Int J Pediatr Otorhinolaryngol. 2016 Jun;85:84-90. doi: 10.1016/j.ijporl.2016.03.025. Epub 2016 Mar 28.

PMID:
27240502
29.

Difficult Laryngeal Exposure in Microlaryngoscopy: Can it be Predicted Preoperatively?

Paul RR, Varghese AM, Mathew J, Chandrasekharan R, Amalanathan S, Asif SK, Kurien M.

Indian J Otolaryngol Head Neck Surg. 2016 Mar;68(1):65-70. doi: 10.1007/s12070-015-0913-9. Epub 2015 Sep 21.

30.

Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels.

Stadler ZK, Battaglin F, Middha S, Hechtman JF, Tran C, Cercek A, Yaeger R, Segal NH, Varghese AM, Reidy-Lagunes DL, Kemeny NE, Salo-Mullen EE, Ashraf A, Weiser MR, Garcia-Aguilar J, Robson ME, Offit K, Arcila ME, Berger MF, Shia J, Solit DB, Saltz LB.

J Clin Oncol. 2016 Jun 20;34(18):2141-7. doi: 10.1200/JCO.2015.65.1067. Epub 2016 Mar 28.

31.

ACE grading-A proposed endoscopic grading system for adenoids and its clinical correlation.

Varghese AM, Naina P, Cheng AT, Asif SK, Kurien M.

Int J Pediatr Otorhinolaryngol. 2016 Apr;83:155-9. doi: 10.1016/j.ijporl.2016.02.002. Epub 2016 Feb 21.

PMID:
26968070
32.

Endoscopic Repair of CSF Rhinorrhea: An Institutional Experience.

Mishra SK, Mathew GA, Paul RR, Asif SK, John M, Varghese AM, Kurien M.

Iran J Otorhinolaryngol. 2016 Jan;28(84):39-43.

33.

Cerebrospinal Fluid from Sporadic Amyotrophic Lateral Sclerosis Patients Induces Mitochondrial and Lysosomal Dysfunction.

Sharma A, Varghese AM, Vijaylakshmi K, Sumitha R, Prasanna VK, Shruthi S, Chandrasekhar Sagar BK, Datta KK, Gowda H, Nalini A, Alladi PA, Christopher R, Sathyaprabha TN, Raju TR, Srinivas Bharath MM.

Neurochem Res. 2016 May;41(5):965-84. doi: 10.1007/s11064-015-1779-7. Epub 2015 Dec 8.

PMID:
26646005
34.

A Randomized Controlled Trial Comparing Intranasal Midazolam and Chloral Hydrate for Procedural Sedation in Children.

Stephen MC, Mathew J, Varghese AM, Kurien M, Mathew GA.

Otolaryngol Head Neck Surg. 2015 Dec;153(6):1042-50. doi: 10.1177/0194599815599381. Epub 2015 Aug 18.

PMID:
26286872
35.

Genomic Profiling of Cancers of Unknown Primary Site: The Next Steps.

Varghese AM, Saltz LB.

JAMA Oncol. 2015 Jul;1(4):541-2. doi: 10.1001/jamaoncol.2015.0939. No abstract available.

PMID:
26181267
36.

First draft genome sequence of a member of the genus mangrovibacter, isolated from an aquaculture farm in India.

Joseph TC, Varghese AM, Baby A, Reghunathan D, Murugadas V, Lalitha KV.

Genome Announc. 2014 Nov 20;2(6). pii: e01209-14. doi: 10.1128/genomeA.01209-14.

37.

Draft Genome Sequence of the Halophilic and Highly Halotolerant Gammaproteobacteria Strain MFB021.

Joseph TC, Baby A, Reghunathan D, Varghese AM, Murugadas V, Lalitha KV.

Genome Announc. 2014 Nov 20;2(6). pii: e01156-14. doi: 10.1128/genomeA.01156-14.

38.

Advancing clinical oncology through genome biology and technology.

Varghese AM, Berger MF.

Genome Biol. 2014 Aug 7;15(8):427. doi: 10.1186/s13059-014-0427-x.

39.

IgG4-related disease with sinonasal involvement: A case series.

Prabhu SM, Yadav V, Irodi A, Mani S, Varghese AM.

Indian J Radiol Imaging. 2014 Apr;24(2):117-20. doi: 10.4103/0971-3026.134384.

40.

A rare case of bilateral nasolabial cysts in a postpartum lady.

Chandrasekharan R, Varghese AM, Mathew J, Ashish G.

Indian J Dent Res. 2014 Mar-Apr;25(2):225-7. doi: 10.4103/0970-9290.135929.

41.

Root canal treatment of a maxillary second premolar with two palatal roots: A case report.

George GK, Varghese AM, Devadathan A.

J Conserv Dent. 2014 May;17(3):290-2. doi: 10.4103/0972-0707.131807.

42.

Role of VEGF and VEGFR2 Receptor in Reversal of ALS-CSF Induced Degeneration of NSC-34 Motor Neuron Cell Line.

Vijayalakshmi K, Ostwal P, Sumitha R, Shruthi S, Varghese AM, Mishra P, Manohari SG, Sagar BC, Sathyaprabha TN, Nalini A, Raju TR, Alladi PA.

Mol Neurobiol. 2015;51(3):995-1007. doi: 10.1007/s12035-014-8757-y. Epub 2014 Jun 1.

PMID:
24880751
43.

Small-cell lung cancers in patients who never smoked cigarettes.

Varghese AM, Zakowski MF, Yu HA, Won HH, Riely GJ, Krug LM, Kris MG, Rekhtman N, Ladanyi M, Wang L, Berger MF, Pietanza MC.

J Thorac Oncol. 2014 Jun;9(6):892-6. doi: 10.1097/JTO.0000000000000142.

44.

Emergency ventilation with a Chevalier Jackson's metal tracheostomy tube.

Syed KA, Paul RR, Varghese AM, Joseph NA.

Int J Pediatr Otorhinolaryngol. 2014 May;78(5):888-90. doi: 10.1016/j.ijporl.2014.03.004. Epub 2014 Mar 13.

PMID:
24680941
45.

Chitotriosidase - a putative biomarker for sporadic amyotrophic lateral sclerosis.

Varghese AM, Sharma A, Mishra P, Vijayalakshmi K, Harsha HC, Sathyaprabha TN, Bharath SM, Nalini A, Alladi PA, Raju TR.

Clin Proteomics. 2013 Dec 2;10(1):19. doi: 10.1186/1559-0275-10-19.

46.

Dacryocystectomy: an uncommon indication--a case report.

Varghese CM, Varghese AM, Syed KA, Paul RR.

Int J Pediatr Otorhinolaryngol. 2014 Jan;78(1):139-41. doi: 10.1016/j.ijporl.2013.10.046. Epub 2013 Nov 7.

PMID:
24268316
47.

ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: an analysis of 1,683 patients with non-small cell lung cancer.

Gainor JF, Varghese AM, Ou SH, Kabraji S, Awad MM, Katayama R, Pawlak A, Mino-Kenudson M, Yeap BY, Riely GJ, Iafrate AJ, Arcila ME, Ladanyi M, Engelman JA, Dias-Santagata D, Shaw AT.

Clin Cancer Res. 2013 Aug 1;19(15):4273-81. doi: 10.1158/1078-0432.CCR-13-0318. Epub 2013 May 31.

48.

Bilateral simultaneous cochlear implantation in children: report of a case and review of literature.

Varghese AM, Mathew J, Alexander A, Thenmozhi K, Evangelin GL, Kurien M.

Indian J Otolaryngol Head Neck Surg. 2012 Mar;64(1):95-6. doi: 10.1007/s12070-011-0219-5. Epub 2011 Apr 12.

49.

Lungs don't forget: Comparison of the KRAS and EGFR mutation profile and survival of collegiate smokers and never smokers with advanced lung cancers.

Varghese AM, Sima CS, Chaft JE, Johnson ML, Riely GJ, Ladanyi M, Kris MG.

J Thorac Oncol. 2013 Jan;8(1):123-5. doi: 10.1097/JTO.0b013e31827914ea.

50.

Response to erlotinib in patients with EGFR mutant advanced non-small cell lung cancers with a squamous or squamous-like component.

Paik PK, Varghese AM, Sima CS, Moreira AL, Ladanyi M, Kris MG, Rekhtman N.

Mol Cancer Ther. 2012 Nov;11(11):2535-40. doi: 10.1158/1535-7163.MCT-12-0163. Epub 2012 Aug 14.

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