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Items: 33

1.

Plasma YKL-40 in the spectrum of neurodegenerative dementia.

Villar-Piqué A, Schmitz M, Hermann P, Goebel S, Bunck T, Varges D, Ferrer I, Riggert J, Llorens F, Zerr I.

J Neuroinflammation. 2019 Jul 12;16(1):145. doi: 10.1186/s12974-019-1531-3.

2.

Cerebrospinal Fluid Total and Phosphorylated α-Synuclein in Patients with Creutzfeldt-Jakob Disease and Synucleinopathy.

Schmitz M, Villar-Piqué A, Llorens F, Gmitterová K, Hermann P, Varges D, Zafar S, Lingor P, Vanderstichele H, Demeyer L, Stoops E, Trojanowski JQ, Lee VM, Zerr I.

Mol Neurobiol. 2019 May;56(5):3476-3483. doi: 10.1007/s12035-018-1313-4. Epub 2018 Aug 22.

PMID:
30136097
3.

Cerebrospinal fluid markers analysis in the differential diagnosis of dementia with Lewy bodies and Parkinson's disease dementia.

Gmitterová K, Gawinecka J, Llorens F, Varges D, Valkovič P, Zerr I.

Eur Arch Psychiatry Clin Neurosci. 2018 Aug 6. doi: 10.1007/s00406-018-0928-9. [Epub ahead of print]

PMID:
30083957
4.

Cerebrospinal fluid neurofilament light levels in neurodegenerative dementia: Evaluation of diagnostic accuracy in the differential diagnosis of prion diseases.

Zerr I, Schmitz M, Karch A, Villar-Piqué A, Kanata E, Golanska E, Díaz-Lucena D, Karsanidou A, Hermann P, Knipper T, Goebel S, Varges D, Sklaviadis T, Sikorska B, Liberski PP, Santana I, Ferrer I, Zetterberg H, Blennow K, Calero O, Calero M, Ladogana A, Sánchez-Valle R, Baldeiras I, Llorens F.

Alzheimers Dement. 2018 Jun;14(6):751-763. doi: 10.1016/j.jalz.2017.12.008. Epub 2018 Feb 3.

PMID:
29391125
5.

Neuropsychological Symptoms in Sporadic Creutzfeldt-Jakob Disease Patients in Germany.

Krasnianski A, Bohling GT, Heinemann U, Varges D, Meissner B, Schulz-Schaeffer WJ, Reif A, Zerr I.

J Alzheimers Dis. 2017;59(1):329-337. doi: 10.3233/JAD-161129.

PMID:
28598840
6.

Evaluation of α-synuclein as a novel cerebrospinal fluid biomarker in different forms of prion diseases.

Llorens F, Kruse N, Schmitz M, Gotzmann N, Golanska E, Thüne K, Zejneli O, Kanata E, Knipper T, Cramm M, Lange P, Zafar S, Sikorska B, Liberski PP, Mitrova E, Varges D, Schmidt C, Sklaviadis T, Mollenhauer B, Zerr I.

Alzheimers Dement. 2017 Jun;13(6):710-719. doi: 10.1016/j.jalz.2016.09.013. Epub 2016 Nov 18.

PMID:
27870938
7.

Doxycycline in early CJD: a double-blinded randomised phase II and observational study.

Varges D, Manthey H, Heinemann U, Ponto C, Schmitz M, Schulz-Schaeffer WJ, Krasnianski A, Breithaupt M, Fincke F, Kramer K, Friede T, Zerr I.

J Neurol Neurosurg Psychiatry. 2017 Feb;88(2):119-125. doi: 10.1136/jnnp-2016-313541. Epub 2016 Nov 2.

8.

Cerebrospinal α-synuclein in α-synuclein aggregation disorders: tau/α-synuclein ratio as potential biomarker for dementia with Lewy bodies.

Llorens F, Schmitz M, Varges D, Kruse N, Gotzmann N, Gmitterová K, Mollenhauer B, Zerr I.

J Neurol. 2016 Nov;263(11):2271-2277. Epub 2016 Aug 20.

PMID:
27544498
9.

Application of an in vitro-amplification assay as a novel pre-screening test for compounds inhibiting the aggregation of prion protein scrapie.

Schmitz M, Cramm M, Llorens F, Candelise N, Müller-Cramm D, Varges D, Schulz-Schaeffer WJ, Zafar S, Zerr I.

Sci Rep. 2016 Jul 7;6:28711. doi: 10.1038/srep28711.

10.

Comparative analysis of cerebrospinal fluid biomarkers in the differential diagnosis of neurodegenerative dementia.

Llorens F, Schmitz M, Karch A, Cramm M, Lange P, Gherib K, Varges D, Schmidt C, Zerr I, Stoeck K.

Alzheimers Dement. 2016 May;12(5):577-89. doi: 10.1016/j.jalz.2015.10.009. Epub 2015 Dec 21.

PMID:
26718584
11.

Increased albumin CSF/serum ratio in dementia with Lewy bodies.

Llorens F, Schmitz M, Gloeckner SF, Kaerst L, Hermann P, Schmidt C, Varges D, Zerr I.

J Neurol Sci. 2015 Nov 15;358(1-2):398-403. doi: 10.1016/j.jns.2015.10.011. Epub 2015 Oct 23.

PMID:
26476775
12.

Clinical findings and diagnosis in genetic prion diseases in Germany.

Krasnianski A, Heinemann U, Ponto C, Kortt J, Kallenberg K, Varges D, Schulz-Schaeffer WJ, Kretzschmar HA, Zerr I.

Eur J Epidemiol. 2016 Feb;31(2):187-96. doi: 10.1007/s10654-015-0049-y. Epub 2015 Jun 16.

PMID:
26076917
13.

Stability and Reproducibility Underscore Utility of RT-QuIC for Diagnosis of Creutzfeldt-Jakob Disease.

Cramm M, Schmitz M, Karch A, Mitrova E, Kuhn F, Schroeder B, Raeber A, Varges D, Kim YS, Satoh K, Collins S, Zerr I.

Mol Neurobiol. 2016 Apr;53(3):1896-1904. doi: 10.1007/s12035-015-9133-2. Epub 2015 Apr 1.

14.

Characteristic CSF prion seeding efficiency in humans with prion diseases.

Cramm M, Schmitz M, Karch A, Zafar S, Varges D, Mitrova E, Schroeder B, Raeber A, Kuhn F, Zerr I.

Mol Neurobiol. 2015 Feb;51(1):396-405. doi: 10.1007/s12035-014-8709-6. Epub 2014 May 9.

15.

A proposal of new diagnostic pathway for fatal familial insomnia.

Krasnianski A, Sanchez Juan P, Ponto C, Bartl M, Heinemann U, Varges D, Schulz-Schaeffer WJ, Kretzschmar HA, Zerr I.

J Neurol Neurosurg Psychiatry. 2014 Jun;85(6):654-9. doi: 10.1136/jnnp-2013-305978. Epub 2013 Nov 18.

16.

Spongiform encephalopathy in siblings with no evidence of protease-resistant prion protein or a mutation in the prion protein gene.

Varges D, Schulz-Schaeffer WJ, Wemheuer WM, Damman I, Schmitz M, Cramm M, Kallenberg K, Shirneshan K, Elkenani M, Markwort S, Faist M, Kohlhase J, Windl O, Zerr I.

J Neurol. 2013 Jul;260(7):1871-9. doi: 10.1007/s00415-013-6897-z. Epub 2013 Apr 2.

PMID:
23546304
17.

Low-abundant cerebrospinal fluid proteome alterations in dementia with Lewy bodies.

Dieks JK, Gawinecka J, Asif AR, Varges D, Gmitterova K, Streich JH, Dihazi H, Heinemann U, Zerr I.

J Alzheimers Dis. 2013;34(2):387-97. doi: 10.3233/JAD-121810.

PMID:
23254635
18.

Genetic prion disease with codon 196 PRNP mutation: clinical and pathological findings.

Schelzke G, Eigenbrod S, Romero C, Varges D, Breithaupt M, Taratuto AL, Kretzschmar HA, Zerr I.

Neurobiol Aging. 2011 Apr;32(4):756.e1-9. doi: 10.1016/j.neurobiolaging.2010.11.023. Epub 2011 Jan 12.

PMID:
21232818
19.

Amyloid-β 1-42 levels are modified by apolipoprotein E ε4 in Creutzfeldt-Jakob disease in a similar manner as in Alzheimer's disease.

Varges D, Jung K, Gawinecka J, Heinemann U, Schmitz M, von Ahsen N, Krasnianski A, Armstrong VW, Zerr I.

J Alzheimers Dis. 2011;23(4):717-26. doi: 10.3233/JAD-2010-101527.

PMID:
21157024
20.

Codon 129 polymorphism and the E200K mutation do not affect the cellular prion protein isoform composition in the cerebrospinal fluid from patients with Creutzfeldt-Jakob disease.

Schmitz M, Schlomm M, Hasan B, Beekes M, Mitrova E, Korth C, Breil A, Carimalo J, Gawinecka J, Varges D, Zerr I.

Eur J Neurosci. 2010 Jun;31(11):2024-31. doi: 10.1111/j.1460-9568.2010.07224.x. Epub 2010 May 31.

PMID:
20529115
21.

8-OHdG in cerebrospinal fluid as a marker of oxidative stress in various neurodegenerative diseases.

Gmitterová K, Heinemann U, Gawinecka J, Varges D, Ciesielczyk B, Valkovic P, Benetin J, Zerr I.

Neurodegener Dis. 2009;6(5-6):263-9. doi: 10.1159/000237221. Epub 2009 Dec 3.

PMID:
19955696
22.

Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease.

Zerr I, Kallenberg K, Summers DM, Romero C, Taratuto A, Heinemann U, Breithaupt M, Varges D, Meissner B, Ladogana A, Schuur M, Haik S, Collins SJ, Jansen GH, Stokin GB, Pimentel J, Hewer E, Collie D, Smith P, Roberts H, Brandel JP, van Duijn C, Pocchiari M, Begue C, Cras P, Will RG, Sanchez-Juan P.

Brain. 2009 Oct;132(Pt 10):2659-68. doi: 10.1093/brain/awp191. Epub 2009 Sep 22. Erratum in: Brain. 2012 Apr;135(Pt 4):1335.

23.

Movement disturbances in the differential diagnosis of Creutzfeldt-Jakob disease.

Edler J, Mollenhauer B, Heinemann U, Varges D, Werner C, Zerr I, Schulz-Schaeffer WJ.

Mov Disord. 2009 Feb 15;24(3):350-6. doi: 10.1002/mds.22253.

PMID:
19053051
24.

MRI in the classical MM1 and the atypical MV2 subtypes of sporadic CJD: an inter-observer agreement study.

Krasnianski A, Kallenberg K, Collie DA, Meissner B, Schulz-Schaeffer WJ, Heinemann U, Varges D, Summers DM, Kretzschmar HA, Talbot T, Will RG, Zerr I.

Eur J Neurol. 2008 Aug;15(8):762-71. doi: 10.1111/j.1468-1331.2008.02209.x.

PMID:
18684308
25.

Isolated cortical signal increase on MR imaging as a frequent lesion pattern in sporadic Creutzfeldt-Jakob disease.

Meissner B, Kallenberg K, Sanchez-Juan P, Krasnianski A, Heinemann U, Varges D, Knauth M, Zerr I.

AJNR Am J Neuroradiol. 2008 Sep;29(8):1519-24. doi: 10.3174/ajnr.A1122. Epub 2008 Jul 3.

26.

Fatal familial insomnia: Clinical features and early identification.

Krasnianski A, Bartl M, Sanchez Juan PJ, Heinemann U, Meissner B, Varges D, Schulze-Sturm U, Kretzschmar HA, Schulz-Schaeffer WJ, Zerr I.

Ann Neurol. 2008 May;63(5):658-61. doi: 10.1002/ana.21358.

PMID:
18360821
27.

[Post-traumatic hypertrophic degeneration of the olivary nucleus with MRI detection of hyperperfusion].

Pilgram SM, Varges D, Knauth M.

Rofo. 2008 Jan;180(1):61-3. Epub 2007 Oct 29. German. No abstract available.

PMID:
17968775
28.

Creutzfeldt-Jakob disease in Germany: a prospective 12-year surveillance.

Heinemann U, Krasnianski A, Meissner B, Varges D, Kallenberg K, Schulz-Schaeffer WJ, Steinhoff BJ, Grasbon-Frodl EM, Kretzschmar HA, Zerr I.

Brain. 2007 May;130(Pt 5):1350-9.

PMID:
17472986
29.

Brain-derived proteins in the CSF: do they correlate with brain pathology in CJD?

Boesenberg-Grosse C, Schulz-Schaeffer WJ, Bodemer M, Ciesielczyk B, Meissner B, Krasnianski A, Bartl M, Heinemann U, Varges D, Eigenbrod S, Kretzschmar HA, Green A, Zerr I.

BMC Neurol. 2006 Sep 21;6:35.

30.

Clinical features and diagnosis of the MM2 cortical subtype of sporadic Creutzfeldt-Jakob disease.

Krasnianski A, Meissner B, Schulz-Schaeffer W, Kallenberg K, Bartl M, Heinemann U, Varges D, Kretzschmar HA, Zerr I.

Arch Neurol. 2006 Jun;63(6):876-80.

PMID:
16769870
31.

Clinical findings and diagnostic tests in the MV2 subtype of sporadic CJD.

Krasnianski A, Schulz-Schaeffer WJ, Kallenberg K, Meissner B, Collie DA, Roeber S, Bartl M, Heinemann U, Varges D, Kretzschmar HA, Zerr I.

Brain. 2006 Sep;129(Pt 9):2288-96. Epub 2006 May 23.

PMID:
16720682
32.

Sporadic Creutzfeldt-Jakob disease: clinical and diagnostic characteristics of the rare VV1 type.

Meissner B, Westner IM, Kallenberg K, Krasnianski A, Bartl M, Varges D, Bösenberg C, Kretzschmar HA, Knauth M, Schulz-Schaeffer WJ, Zerr I.

Neurology. 2005 Nov 22;65(10):1544-50. Epub 2005 Oct 12.

PMID:
16221949
33.

Clinical course in young patients with sporadic Creutzfeldt-Jakob disease.

Boesenberg C, Schulz-Schaeffer WJ, Meissner B, Kallenberg K, Bartl M, Heinemann U, Krasnianski A, Stoeck K, Varges D, Windl O, Kretzschmar HA, Zerr I.

Ann Neurol. 2005 Oct;58(4):533-43.

PMID:
16037975

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